Entry: PS00269

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General information about the entry

Entry name [info] DEFENSIN
Accession [info] PS00269
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); OCT-1993 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00242

Name and characterization of the entry

Description [info] Mammalian defensins signature.
Pattern [info]
C-x-C-x(3,5)-C-x(7)-G-x-C-x(9)-C-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_08 which contains 546'238 sequence entries.


Total number of hits 60 in 60 different sequences
Number of true positive hits 59 in 59 different sequences
Number of 'unknown' hits
Number of false positive hits 1
Number of false negative sequences 11
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 98.33 %
Recall (true positives / (true positives + false negatives)) 84.29 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 5
Site [info] disulfide at position 9
Site [info] disulfide at position 11
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
59 sequences

DEF1A_CAVPO (P11478), DEF1B_CAVPO (Q64365), DEF1_HUMAN  (P59665), 
DEF1_MACMU  (P60030), DEF1_MESAU  (P81465), DEF1_PANTR  (Q5G863), 
DEF1_PAPHA  (P84757), DEF1_RABIT  (P07469), DEF1_RAT    (Q62716), 
DEF2_CAVPO  (P49112), DEF2_MACMU  (P82317), DEF2_MESAU  (P81466), 
DEF2_RABIT  (P07468), DEF2_RAT    (Q62715), DEF3A_RAT   (Q62713), 
DEF3B_RAT   (Q9Z1F1), DEF3_HUMAN  (P59666), DEF3_MACMU  (P60031), 
DEF3_MESAU  (P81467), DEF3_PAPHA  (P84758), DEF3_RABIT  (P01376), 
DEF4_HUMAN  (P12838), DEF4_MACMU  (P82319), DEF4_MESAU  (P81468), 
DEF4_PANTR  (Q5G862), DEF4_PAPHA  (P86724), DEF4_RABIT  (P01377), 
DEF4_RAT    (Q62714), DEF5_HUMAN  (Q01523), DEF5_PANTR  (Q5G861), 
DEF5_RABIT  (P07467), DEF5_RAT    (P82106), DEF6_HUMAN  (Q01524), 
DEF6_MACMU  (P82320), DEF6_PANTR  (Q5G860), DEF6_RABIT  (P07466), 
DEF7_RABIT  (P80223), DEF8_MACMU  (P60032), DEFA1_MOUSE (P11477), 
DEFA1_ORNAN (P0C8A1), DEFA2_MOUSE (P28309), DEFA2_ORNAN (P0C8A2), 
DEFA3_MOUSE (P28310), DEFA3_ORNAN (P0C8A3), DEFA5_MOUSE (P28312), 
DEFA6_MOUSE (P50704), DEFA7_MOUSE (P50705), DEFA8_MOUSE (P50706), 
DEFA9_MOUSE (P50707), DFA10_MOUSE (P50708), DFA11_MOUSE (P50709), 
DFA13_MOUSE (P50711), DFA14_MOUSE (P50712), DFA15_MOUSE (P50713), 
DFA16_MOUSE (P50714), DFA17_MOUSE (Q64016), DFA23_MOUSE (Q5G866), 
DFA24_MOUSE (Q5G865), DFA26_MOUSE (Q3L180)
» More

UniProtKB/Swiss-Prot
False negative sequences
11 sequences

BTDA_PAPAN  (B6ULW4), BTDB_PAPAN  (B6ULW5), BTDC_PAPAN  (B6ULW6), 
BTDD_PAPAN  (B6ULW7), DEF7_PANTR  (Q5G859), DEFA4_MOUSE (P28311), 
DEFA4_ORNAN (P0C8A4), RK1_RABIT   (P81655), RTD1A_MACMU (P82270), 
RTD1B_MACMU (P82271), RTD3_MACMU  (Q9GLR2)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

BTDA_PAPHA  (P86722), BTDB_PAPHA  (P86723)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

KRUC_SHEEP  (P26372)

		
PDB
[Detailed view]
29 PDB

1DFN; 1ZMM; 1ZMP; 1ZMQ; 2KHT; 2LXZ; 2PM1; 2PM4; 2PM5; 3GNY; 3H6C; 3HJ2; 3HJD; 3I5W; 3LO1; 3LO2; 3LO4; 3LO6; 3LO9; 3LOE; 3LVX; 3QTE; 4E82; 4E83; 4E86; 4LB1; 4LB7; 4LBB; 4LBF
» More

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