Entry: PS00279

General information about the entry
Entry name MACPF_1
Accession number PS00279
Entry type PATTERN
Date APR-1990 (CREATED); APR-1990 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00251
Name and characterization of the entry
DescriptionMembrane attack complex/perforin (MACPF) domain signature.
Pattern Y-x(6)-[FY]-G-T-H-[FY].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 28 hits in 28 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 28 hits in 28 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 25
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 52.83 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CO6_BOVIN   (Q29RU4), CO6_HUMAN   (P13671), CO6_PANTR   (P61134), 
CO6_PONPY   (P61135), CO6_RAT     (Q811M5), CO7_BOVIN   (Q29RQ1), 
CO7_HUMAN   (P10643), CO7_PIG     (Q9TUQ3), CO7_PONAB   (Q5RAD0), 
CO8A_HUMAN  (P07357), CO8A_MOUSE  (Q8K182), CO8A_RABIT  (P98136), 
CO8B_HUMAN  (P07358), CO8B_MOUSE  (Q8BH35), CO8B_ONCMY  (Q90X85), 
CO8B_PAROL  (Q9PVW7), CO8B_RAT    (P55314), CO9_BOVIN   (Q3MHN2), 
CO9_HORSE   (P48770), CO9_HUMAN   (P02748), CO9_MOUSE   (P06683), 
CO9_ONCMY   (P06682), CO9_RABIT   (P48747), CO9_RAT     (Q62930), 
CO9_TAKRU   (P79755), PERF_HUMAN  (P14222), PERF_MOUSE  (P10820), 
PERF_RAT    (P35763)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
CAD1_ARATH  (Q9C7N2), CO8B_RABIT  (P98137), DBC1_BOVIN  (Q5E9L2), 
DBC1_CHICK  (Q7ZZR3), DBC1_HUMAN  (O60477), DBC1_MOUSE  (Q920P3), 
DBC1_RAT    (Q925T8), FAM5B_HUMAN (Q9C0B6), FAM5B_MOUSE (Q6DFY8), 
FAM5B_PONAB (Q5RDR5), FAM5B_RAT   (Q8K1M8), FAM5C_HUMAN (Q76B58), 
FAM5C_MOUSE (Q499E0), FAM5C_RAT   (Q8K1M7), MACP1_ARATH (Q8L612), 
MACP2_ARATH (Q9STW5), MPEG1_BOVIN (Q2KJC3), MPEG1_HUMAN (Q2M385), 
MPEG1_MOUSE (A1L314), MPEG1_PONAB (Q5RBP9), MPEG1_RAT   (Q9WV57), 
NSL1_ARATH  (Q9SGN6), TX60A_ACTVL (Q76DT2), TX60A_PHYSE (P58911), 
TX60B_PHYSE (P58912)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 2QQH; 2RD7; 3NSJ; 3OJY; 3T5O; 4A5W; 4E0S;

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