Entry: PS00279

General information about the entry

Entry name [info] MACPF_1
Accession [info] PS00279
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-1990 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00251

Name and characterization of the entry

Description [info] Membrane attack complex/perforin (MACPF) domain signature.
Pattern [info]
Y-x(6)-[FY]-G-T-H-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 29 in 29 different sequences
Number of true positive hits 29 in 29 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 25
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 53.70 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
29 sequences

CO6_BOVIN   (Q29RU4    ), CO6_HUMAN   (P13671    ), CO6_PANTR   (P61134    ), 
CO6_PONPY   (P61135    ), CO6_RAT     (Q811M5    ), CO7_BOVIN   (Q29RQ1    ), 
CO7_HUMAN   (P10643    ), CO7_PIG     (Q9TUQ3    ), CO7_PONAB   (Q5RAD0    ), 
CO8A_HUMAN  (P07357    ), CO8A_MOUSE  (Q8K182    ), CO8A_RABIT  (P98136    ), 
CO8B_HUMAN  (P07358    ), CO8B_MOUSE  (Q8BH35    ), CO8B_ONCMY  (Q90X85    ), 
CO8B_PAROL  (Q9PVW7    ), CO8B_RAT    (P55314    ), CO9_BOVIN   (Q3MHN2    ), 
CO9_HORSE   (P48770    ), CO9_HUMAN   (P02748    ), CO9_MOUSE   (P06683    ), 
CO9_ONCMY   (P06682    ), CO9_RABIT   (P48747    ), CO9_RAT     (Q62930    ), 
CO9_TAKRU   (P79755    ), PERF_HUMAN  (P14222    ), PERF_MOUSE  (P10820    ), 
PERF_RAT    (P35763    ), PV21_POMCA  (P0C8G6    )
» more

UniProtKB/Swiss-Prot
False negative sequences
25 sequences

BRNP1_BOVIN (Q5E9L2    ), BRNP1_CHICK (Q7ZZR3    ), BRNP1_HUMAN (O60477    ), 
BRNP1_MOUSE (Q920P3    ), BRNP1_RAT   (Q925T8    ), BRNP2_HUMAN (Q9C0B6    ), 
BRNP2_MOUSE (Q6DFY8    ), BRNP2_PONAB (Q5RDR5    ), BRNP2_RAT   (Q8K1M8    ), 
BRNP3_HUMAN (Q76B58    ), BRNP3_MOUSE (Q499E0    ), BRNP3_RAT   (Q8K1M7    ), 
CAD1_ARATH  (Q9C7N2    ), CO8B_RABIT  (P98137    ), MACP1_ARATH (Q8L612    ), 
MACP2_ARATH (Q9STW5    ), MPEG1_BOVIN (Q2KJC3    ), MPEG1_HUMAN (Q2M385    ), 
MPEG1_MOUSE (A1L314    ), MPEG1_PONAB (Q5RBP9    ), MPEG1_RAT   (Q9WV57    ), 
NSL1_ARATH  (Q9SGN6    ), TX60A_ACTVL (Q76DT2    ), TX60A_PHYSE (P58911    ), 
TX60B_PHYSE (P58912    )
» more

PDB
[Detailed view]
8 PDB

2QQH; 2RD7; 3NSJ; 3OJY; 3T5O; 4A5W; 4E0S; 5FMW

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission