Entry: PS00282

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General information about the entry

Entry name [info] KAZAL_1
Accession [info] PS00282
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00254

Name and characterization of the entry

Description [info] Kazal serine protease inhibitors family signature.
Pattern [info]
C-x(4)-{C}-x(2)-C-x-{A}-x(4)-Y-x(3)-C-x(2,3)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 241 in 212 different sequences
Number of true positive hits 239 in 210 different sequences
Number of 'unknown' hits
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 57
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.17 %
Recall (true positives / (true positives + false negatives)) 80.74 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 7
Site [info] disulfide at position 1
Site [info] disulfide at position 5
Site [info] disulfide at position 11
Site [info] disulfide at position 13
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
210 sequences

DPGN_DIPMA  (O96790), IAC1_BOVIN  (P01000), IACA_PIG    (P00999), 
IACS_PIG    (P26461), IBD3_HIRME  (P09865), ICHY_CAIMO  (P83039), 
IKP1_PHYSA  (P83578), IKP2_PHYSA  (P83579), IMSP6_VENPH (P86987), 
IOV7_CHICK  (P10184), IOVO_ACRVU  (P68469), IOVO_AEPAR  (P52241), 
IOVO_AFRCO  (P52258), IOVO_AIXGA  (P68144), IOVO_AIXSP  (P68145), 
IOVO_ALECH  (P68146), IOVO_ALERU  (P68147), IOVO_ALOAE  (P68148), 
IOVO_ANACA  (P68149), IOVO_ANAPL  (P68150), IOVO_ANHNO  (P05565), 
IOVO_ANSAN  (P68389), IOVO_ANSIN  (P68437), IOVO_ANSSE  (P05567), 
IOVO_ANTVI  (P68381), IOVO_AQUAU  (P68376), IOVO_ARBTO  (P05601), 
IOVO_ARGAR  (P05608), IOVO_AYTAM  (P68391), IOVO_BALPA  (P52239), 
IOVO_BAMTH  (P52259), IOVO_BONUM  (P05585), IOVO_BRACA  (P68393), 
IOVO_BUGCA  (P68383), IOVO_CALCC  (P68387), IOVO_CALGM  (P68388), 
IOVO_CALSC  (P05589), IOVO_CALSP  (P05588), IOVO_CARME  (P52242), 
IOVO_CARPF  (P52265), IOVO_CARRE  (P05616), IOVO_CASBE  (P62336), 
IOVO_CASCA  (P62337), IOVO_CATWA  (P67957), IOVO_CENUR  (P67945), 
IOVO_CERNO  (P05575), IOVO_CHACH  (P67887), IOVO_CHATO  (P67888), 
IOVO_CHECA  (P68394), IOVO_CHICK  (P01005), IOVO_CHLPI  (P68151), 
IOVO_CHRAM  (P68128), IOVO_CHRPC  (P68127), IOVO_CHRRI  (P68386), 
IOVO_CIRAE  (P05579), IOVO_COLVI  (P05591), IOVO_CORAL  (P52243), 
IOVO_CORMO  (P52244), IOVO_COSCO  (P05571), IOVO_COTDE  (P05600), 
IOVO_COTJA  (P01003), IOVO_CROAU  (P67951), IOVO_CROCS  (P52245), 
IOVO_CROMA  (P67952), IOVO_CYACY  (P68152), IOVO_CYGAT  (P68129), 
IOVO_CYGOL  (P68130), IOVO_CYRMO  (P05592), IOVO_DACNO  (P05617), 
IOVO_DENAC  (P67890), IOVO_DENAR  (P67889), IOVO_DENAU  (P67891), 
IOVO_DENBI  (P67892), IOVO_DENEY  (P05569), IOVO_DENVD  (P05570), 
IOVO_DRONO  (P05560), IOVO_EUDEL  (P05562), IOVO_FRAAF  (P05594), 
IOVO_FRACO  (P05595), IOVO_FRAER  (P05596), IOVO_FRAFR  (P05597), 
IOVO_FRAPO  (P05598), IOVO_FULAT  (P68378), IOVO_GALAS  (P52266), 
IOVO_GALCH  (P68379), IOVO_GALVA  (P52267), IOVO_GEOCA  (P05615), 
IOVO_GRUJA  (P68380), IOVO_GRUVI  (P68382), IOVO_GUIGU  (P52246), 
IOVO_GUTPU  (P52260), IOVO_GYPCO  (P68374), IOVO_HALAL  (P52268), 
IOVO_HALIN  (P05577), IOVO_LAGLU  (P67961), IOVO_LARMA  (P68385), 
IOVO_LEIOC  (P05581), IOVO_LOPBU  (P52261), IOVO_LOPCU  (P68154), 
IOVO_LOPDI  (P67893), IOVO_LOPED  (P67953), IOVO_LOPIG  (P67894), 
IOVO_LOPIM  (P67950), IOVO_LOPLE  (P52262), IOVO_LOPNY  (P67954), 
IOVO_LOPSP  (P68153), IOVO_LOPSW  (P67955), IOVO_MEGFR  (P05580), 
IOVO_MELGA  (P68390), IOVO_MELOE  (P68436), IOVO_NECMO  (P68377), 
IOVO_NEOJU  (P68155), IOVO_NETRU  (P68392), IOVO_NOTCI  (P05561), 
IOVO_NOTPE  (P52248), IOVO_NUMME  (P68468), IOVO_NYCNY  (P05566), 
IOVO_OPIHO  (P52249), IOVO_OREPI  (P05587), IOVO_ORTVE  (P05582), 
IOVO_OXYJA  (P68131), IOVO_OXYVI  (P68132), IOVO_PAVCR  (P05609), 
IOVO_PAVMU  (P52263), IOVO_PENJC  (P67895), IOVO_PENSU  (P67896), 
IOVO_PERPE  (P05599), IOVO_PHAAL  (P67940), IOVO_PHACO  (P68470), 
IOVO_PHASU  (P05564), IOVO_PHAVE  (P68471), IOVO_PIPPP  (P05584), 
IOVO_PODST  (P52264), IOVO_POLBI  (P05607), IOVO_POLNP  (P52250), 
IOVO_POLRA  (P68375), IOVO_PTEPE  (P67943), IOVO_PUCMA  (P67956), 
IOVO_PYGAD  (P67941), IOVO_RHEAM  (P67942), IOVO_RHYFU  (P52251), 
IOVO_ROLRO  (P52252), IOVO_SARME  (P68156), IOVO_SCYNO  (P52253), 
IOVO_SPHHU  (P05563), IOVO_STRCA  (P05557), IOVO_SYREL  (P67958), 
IOVO_SYRHU  (P67959), IOVO_SYRMI  (P52269), IOVO_SYRRE  (P05605), 
IOVO_SYRSO  (P67960), IOVO_TADRA  (P68157), IOVO_TINMA  (P52254), 
IOVO_TRABL  (P67946), IOVO_TRACA  (P67947), IOVO_TRASA  (P67948), 
IOVO_TRATE  (P67949), IOVO_TURME  (P52256), IOVO_TURSY  (P05611), 
IOVO_TYMCU  (P67944), IOVO_VANSP  (P68384), IOVO_VULGR  (P20846), 
IPSG_CANFA  (P01002), IPSG_FELCA  (P08480), IPSG_MARMT  (P81482), 
IPSG_MELME  (P16226), IPSG_MUSLU  (P81481), IPSG_PANLE  (P08481), 
IPSG_UNCUN  (P81262), IPSG_VULVU  (P08479), ISK10_MOUSE (Q8CAC8), 
ISK11_MOUSE (Q09TK7), ISK12_MOUSE (Q9D256), ISK13_MOUSE (Q3UTS8), 
ISK13_RAT   (D3ZVP0), ISK14_HUMAN (Q6IE38), ISK14_RAT   (Q6IE46), 
ISK1L_CHICK (P85000), ISK1_ANGAN  (P11706), ISK1_BOVIN  (P00996), 
ISK1_CANFA  (P04542), ISK1_HORSE  (P81634), ISK1_HUMAN  (P00995), 
ISK1_MONDO  (P81635), ISK1_PIG    (P00998), ISK1_RAT    (P09655), 
ISK1_SHEEP  (P00997), ISK1_STRCA  (Q9PSM2), ISK2_HUMAN  (P20155), 
ISK2_MACFA  (P34953), ISK2_MOUSE  (Q8BMY7), ISK2_RAT    (Q6IE49), 
ISK3_MOUSE  (P09036), ISK3_RAT    (P09656), ISK4_HUMAN  (O60575), 
ISK4_MOUSE  (O35679), ISK4_PIG    (P37109), ISK5_HUMAN  (Q9NQ38), 
ISK6_BOVIN  (P01001), ISK6_HUMAN  (Q6UWN8), ISK6_MOUSE  (Q8BT20), 
ISK6_RAT    (Q6IE47), ISK7_HUMAN  (P58062), ISK7_MOUSE  (Q6IE32), 
ISK7_RAT    (Q6IE51), ISK9_HUMAN  (Q5DT21), LDTI_HIRME  (P80424), 
RECK_HUMAN  (O95980), RECK_MOUSE  (Q9Z0J1), THBI_RHOPR  (Q06684)
» More

UniProtKB/Swiss-Prot
False negative sequences
57 sequences

CALT_CAVPO  (P22074), ESM1_DROME  (O97176), ESM1_DROSI  (B4QW11), 
FSTA_DANRE  (Q9YHV4), FSTL1_HUMAN (Q12841), FSTL1_MOUSE (Q62356), 
FSTL1_PONAB (Q5R9Y1), FSTL1_RAT   (Q62632), FSTL3_BOVIN (Q1LZB9), 
FSTL3_HUMAN (O95633), FSTL3_MOUSE (Q9EQC7), FSTL3_RAT   (Q99PW7), 
FSTL4_HUMAN (Q6MZW2), FSTL4_MOUSE (Q5STE3), FSTL5_HUMAN (Q8N475), 
FSTL5_MOUSE (Q8BFR2), FST_BOVIN   (P50291), FST_BUBBU   (A5YT95), 
FST_CHICK   (Q90844), FST_HORSE   (O62650), FST_HUMAN   (P19883), 
FST_MOUSE   (P47931), FST_PIG     (P10669), FST_RAT     (P21674), 
FST_SHEEP   (P31514), FST_XENLA   (P31515), HTR1B_DANRE (A9JRB3), 
HTRA1_BOVIN (F1N152), HTRA1_RAT   (Q9QZK5), HTRA1_XENLA (A6YFB5), 
HTRA1_XENTR (A4IHA1), HTRA3_HUMAN (P83110), HTRA3_MOUSE (Q9D236), 
HTRA3_RAT   (D3ZA76), HTRA4_BOVIN (E1BJW1), HTRA4_HUMAN (P83105), 
IELA_ANESU  (P16895), IGFBP_CUPSA (G4V4G1), IPK2_CENMR  (P84755), 
MCPI_MELCP  (P82968), SPIKL_MOUSE (Q8CEK3), TU11_LOPAL  (P0DKM9), 
TU91_GEMLI  (P0DKT5), TU91_IOTCI  (P0DKM8), TU91_LOPOL  (P0DKM7), 
TU92_GEMSO  (P0DKT2), TU92_IOTCI  (P0DKT4), TU92_POLAB  (P0DKT1), 
TU93_GEMSP  (P0DKT3), VASOT_HYBBI (P84843), WFKN1_HUMAN (Q96NZ8), 
WFKN1_MOUSE (Q8R0S6), WFKN1_RAT   (P0C5J5), WFKN2_BOVIN (Q08E66), 
WFKN2_HUMAN (Q8TEU8), WFKN2_MOUSE (Q7TQN3), WFKN_DANRE  (Q6NUX0)
» More

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

MADD_CAEEL  (O02626), TUL1_YEAST  (P36096)

		
PDB
[Detailed view]
67 PDB

1AN1; 1BUS; 1CGI; 1CGJ; 1CHO; 1CSO; 1CT0; 1CT2; 1CT4; 1DS2; 1DS3; 1HJA; 1HPT; 1IY5; 1IY6; 1KMA; 1LDT; 1M8B; 1M8C; 1OMT; 1OMU; 1OVO; 1PCE; 1PPF; 1R0R; 1SGD; 1SGE; 1SGN; 1SGP; 1SGQ; 1SGR; 1SGY; 1TBQ; 1TBR; 1TGS; 1TUR; 1TUS; 1UVF; 1UVG; 1Y1C; 1YU6; 1Z7K; 2BUS; 2GKR; 2GKT; 2GKV; 2JXD; 2KMO; 2KMP; 2KMQ; 2KMR; 2LEO; 2NU0; 2NU1; 2NU2; 2NU3; 2NU4; 2OVO; 2SGD; 2SGE; 2SGF; 2SGP; 2SGQ; 3OVO; 3SGB; 3SGQ; 4OVO
» More

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