Entry: PS00284

Forthcoming changes to the profile format
General information about the entry

Entry name [info] SERPIN
Accession [info] PS00284
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); DEC-2004 (DATA UPDATE); SEP-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00256

Name and characterization of the entry

Description [info] Serpins signature.
Pattern [info]
[LIVMFY]-{G}-[LIVMFYAC]-[DNQ]-[RKHQS]-[PST]-F-[LIVMFY]-[LIVMFYC]-x-
[LIVMFAH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_10 which contains 546'790 sequence entries.


Total number of hits 339 in 339 different sequences
Number of true positive hits 232 in 232 different sequences
Number of 'unknown' hits
Number of false positive hits 107 in 107 different sequences
Number of false negative sequences 38
Number of 'partial' sequences 13
Precision (true positives / (true positives + false positives)) 68.44 %
Recall (true positives / (true positives + false negatives)) 85.93 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
232 sequences

A1AF_CAVPO  (P22324), A1AF_RABIT  (P23035), A1AS_CAVPO  (P22325), 
A1AT1_HORSE (P38028), A1AT1_MOUSE (P07758), A1AT2_HORSE (P38029), 
A1AT2_MOUSE (P22599), A1AT3_MOUSE (Q00896), A1AT4_HORSE (P38031), 
A1AT4_MOUSE (Q00897), A1AT5_MOUSE (Q00898), A1AT6_MOUSE (Q9DCQ7), 
A1ATR_HUMAN (P20848), A1AT_BOMMO  (P22922), A1AT_BOVIN  (P34955), 
A1AT_CALCN  (O54763), A1AT_CHLAE  (O00394), A1AT_CYPCA  (P32759), 
A1AT_HUMAN  (P01009), A1AT_MACEU  (P38027), A1AT_MUSCR  (P26595), 
A1AT_MUSSA  (Q63969), A1AT_PAPAN  (P01010), A1AT_PIG    (P50447), 
A1AT_PONAB  (Q5RCW5), A1AT_RAT    (P17475), A1AT_SHEEP  (P12725), 
A2AP_BOVIN  (P28800), A2AP_HUMAN  (P08697), A2AP_MOUSE  (Q61247), 
A76A_DROME  (Q9VVW1), AACT_HUMAN  (P01011), AACT_PONAB  (Q5R536), 
ACH1_BOMMO  (Q03383), ACH2_BOMMO  (P80034), ALLT_SPETR  (O54762), 
ALMM_TAMSI  (O54757), ALMS_SPETR  (O54761), ALMS_TAMSI  (O54758), 
ALSI_TAMSI  (O54760), ALST_TAMSI  (O54759), ANGT_CALJA  (Q9TSZ0), 
ANGT_GORGO  (Q9GLP6), ANGT_HUMAN  (P01019), ANGT_PANTR  (Q9GLN8), 
ANGT_SHEEP  (P20757), ANT3_HUMAN  (P01008), ANT3_MOUSE  (P32261), 
ANT3_PONAB  (Q5R5A3), ANT3_SHEEP  (P32262), BSZ7_HORVU  (Q43492), 
CBG_BOVIN   (E1BF81), CBG_HUMAN   (P08185), CBG_MESAU   (Q60543), 
CBG_MOUSE   (Q06770), CBG_PIG     (Q9GK37), CBG_PONAB   (Q5R9E3), 
CBG_RABIT   (P23775), CBG_RAT     (P31211), CBG_SAISC   (P50451), 
CBG_SHEEP   (P49920), CBG_URSAR   (B2D1U1), EP45_XENLA  (Q00387), 
F12AI_BOVIN (P50448), GDN_HUMAN   (P07093), GDN_MOUSE   (Q07235), 
GDN_RAT     (P07092), HEP2_HUMAN  (P05546), HEP2_MOUSE  (P49182), 
HEP2_RABIT  (P47776), HEP2_RAT    (Q64268), HP55_TAMSI  (Q09055), 
IC1_HUMAN   (P05155), IC1_MOUSE   (P97290), IC1_RABIT   (Q9TRG2), 
IC1_RAT     (Q6P734), ILEUA_MOUSE (Q9D154), ILEUA_RAT   (Q4G075), 
ILEUB_MOUSE (Q8VHP7), ILEUC_MOUSE (Q5SV42), ILEU_BOVIN  (Q1JPB0), 
ILEU_HORSE  (P05619), ILEU_HUMAN  (P30740), ILEU_PIG    (P80229), 
ILEU_XENLA  (Q52L45), ILEU_XENTR  (Q5I0S8), IPSP_BOVIN  (Q9N2I2), 
IPSP_HUMAN  (P05154), KAIN_HUMAN  (P29622), KAIN_PONAB  (Q5RCR2), 
NEUS_CHICK  (Q90935), NEUS_HUMAN  (Q99574), NEUS_MOUSE  (O35684), 
NEUS_RAT    (Q9JLD2), OVALX_CHICK (P01013), OVALY_CHICK (P01014), 
OVAL_CHICK  (P01012), OVAL_COTCO  (Q6V115), OVAL_COTJA  (P19104), 
OVAL_DRONO  (E2RVI8), OVAL_MELGA  (O73860), PAI1_BOVIN  (P13909), 
PAI1_HUMAN  (P05121), PAI1_MOUSE  (P22777), PAI1_NEOVI  (P50449), 
PAI1_PIG    (P79335), PAI1_RAT    (P20961), PAI2_HUMAN  (P05120), 
PAI2_MOUSE  (P12388), PAI2_RAT    (P29524), PEDF_BOVIN  (Q95121), 
PEDF_HUMAN  (P36955), PEDF_MOUSE  (P97298), SERA_MANSE  (P14754), 
SERP3_BOVIN (A6QQ92), SERP3_DANRE (B0UYL8), SERP3_HUMAN (A8MV23), 
SERPH_BOVIN (Q2KJH6), SERPH_CHICK (P13731), SERPH_HUMAN (P50454), 
SERPH_MOUSE (P19324), SERPH_PONAB (Q5RBS3), SERPH_RAT   (P29457), 
SPA12_MOUSE (Q7TMF5), SPA31_BOVIN (Q9TTE1), SPA32_BOVIN (A2I7M9), 
SPA33_BOVIN (Q3ZEJ6), SPA34_BOVIN (A2I7N0), SPA35_BOVIN (A2I7N1), 
SPA36_BOVIN (A2I7N2), SPA37_BOVIN (A2I7N3), SPA38_BOVIN (A6QPQ2), 
SPA3C_MOUSE (P29621), SPA3F_MOUSE (Q80X76), SPA3G_MOUSE (Q5I2A0), 
SPA3K_CAVPO (P22323), SPA3K_MOUSE (P07759), SPA3K_RAT   (P05545), 
SPA3L_RAT   (P05544), SPA3M_MOUSE (Q03734), SPA3M_RAT   (Q63556), 
SPA3N_MOUSE (Q91WP6), SPA3N_RAT   (P09006), SPA9_HUMAN  (Q86WD7), 
SPB10_BOVIN (A5PJK0), SPB10_CALJA (B0CMB0), SPB10_CALMO (B1MTC3), 
SPB10_HUMAN (P48595), SPB10_MOUSE (Q8K1K6), SPB10_OTOGA (B4USX2), 
SPB10_PAPAN (A9RA96), SPB10_RAT   (Q8K3K4), SPB10_RHIFE (B2KI30), 
SPB10_SORAR (B3RFC3), SPB11_HUMAN (Q96P15), SPB12_HUMAN (Q96P63), 
SPB12_MOUSE (Q9D7P9), SPB13_HUMAN (Q9UIV8), SPB13_MOUSE (Q8CDC0), 
SPB3_HUMAN  (P29508), SPB4_HUMAN  (P48594), SPB5_CALMO  (B1MTB7), 
SPB5_HUMAN  (P36952), SPB5_MOUSE  (P70124), SPB5_RAT    (P70564), 
SPB5_XENLA  (Q6GLQ1), SPB5_XENTR  (Q5M8J5), SPB6_BOVIN  (O02739), 
SPB6_HUMAN  (P35237), SPB6_MACFA  (Q4R3G2), SPB6_MOUSE  (Q60854), 
SPB6_PONAB  (Q5R899), SPB7_HUMAN  (O75635), SPB7_MOUSE  (Q9D695), 
SPB8_BOVIN  (Q5BIR5), SPB8_HUMAN  (P50452), SPB8_MOUSE  (O08800), 
SPB9_HUMAN  (P50453), SPI1_CWPXB  (P42927), SPI1_MYXVL  (P12393), 
SPI1_RABPU  (P42928), SPI1_VACCC  (P20531), SPI1_VACCW  (P15058), 
SPI1_VAR67  (P33829), SPI21_RAT   (P09005), SPI24_APOSY (Q60396), 
SPI2B_VACCC (P20842), SPI2_CWPXB  (P07385), SPI2_HUMAN  (O75830), 
SPI2_MOUSE  (Q9JK88), SPI2_MYXVL  (P68565), SPI2_MYXVU  (P68566), 
SPI2_RABPU  (P42926), SPI2_VACCW  (P15059), SPI2_VAR67  (P33830), 
SPI_CYACP   (Q6J201), SPZ10_ARATH (Q9SIR9), SPZ12_ORYSJ (Q5NBM0), 
SPZ1A_WHEAT (Q41593), SPZ1B_WHEAT (P93693), SPZ1C_WHEAT (Q9ST58), 
SPZ1_ARATH  (Q9SH52), SPZ1_ORYSJ  (Q94DW6), SPZ2A_WHEAT (Q9ST57), 
SPZ2B_WHEAT (P93692), SPZ2_ARATH  (Q9ZQR6), SPZ3_ARATH  (O48706), 
SPZ4_ARATH  (Q9M1T7), SPZ4_HORVU  (P06293), SPZ5_ARATH  (O04582), 
SPZ9_ORYSJ  (Q2R8P2), SPZXA_ORYSJ (Q75H81), SPZXB_ORYSJ (Q10GX0), 
SPZX_ARATH  (Q9S7T8), SPZX_HORVU  (Q40066), THBG_BOVIN  (Q9TT36), 
THBG_HUMAN  (P05543), THBG_PANTR  (P61640), THBG_PIG    (Q9TT35), 
THBG_RAT    (P35577), THBG_SHEEP  (P50450), UFAP2_PIG   (P46202), 
UFAP_PIG    (P16708), UTMP_BOVIN  (P46201), UTMP_SHEEP  (P21814), 
V044_FOWPN  (Q9J5F9), V204_FOWPN  (Q9J531), Y049_PYRAE  (Q8ZZW3), 
Y1782_THEKO (Q5JJ64), Y2246_METAC (Q8TNN7), Y2678_METMA (Q8PTN8), 
Y3388_METAC (Q8TKL5)
» More

UniProtKB/Swiss-Prot
False negative sequences
38 sequences

A1AT_DIDVI  (Q03044), A1AT_MERUN  (Q64118), A1AT_MESAU  (P97277), 
ANGT_MOUSE  (P11859), ANGT_RAT    (P01015), ANT3_BOVIN  (P41361), 
HMSD_HUMAN  (A8MTL9), IPSP_MOUSE  (P70458), SPA11_HUMAN (Q86U17), 
SPA11_MOUSE (Q8CIE0), SPA12_HUMAN (Q8IW75), SPA12_RAT   (Q8R4Z1), 
SPA9_MOUSE  (Q9D7D2), SPB10_CHICK (O73790), SPB11_MOUSE (Q9CQV3), 
SPI1_SWPVK  (Q08519), SPI3_LONON  (Q5MGH0), SPI3_VACCA  (Q85339), 
SPI3_VACCC  (P20532), SPI3_VACCW  (P18384), SPI3_VAR67  (P33831), 
SPZ10_ORYSJ (Q7XMK1), SPZ11_ORYSJ (Q7XMK0), SPZ2A_ORYSJ (Q53KS8), 
SPZ2B_ORYSJ (Q53KS9), SPZ5_ORYSJ  (Q53MD3), SPZ6A_ORYSJ (Q53Q31), 
SPZ6B_ORYSJ (Q53Q32), SPZ6C_ORYSJ (Q53MD1), SPZ8_ORYSJ  (Q53P09), 
THBG_MOUSE  (P61939), V010_FOWPN  (Q9J5J1), V040_FOWPN  (Q9J5G3), 
V251_FOWPN  (P14369), Y2613_METAC (Q8TMP0), YR700_MIMIV (Q7T6X8), 
ZPI_HUMAN   (Q9UK55), ZPI_RAT     (Q62975)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
13 sequences

A1AT3_HORSE (P38030), A1AT_CHILA  (P38026), A2AP_STRCA  (P83168), 
ANGT1_BOTJA (Q10581), ANGT2_BOTJA (Q10582), ANGT_BOVIN  (P01017), 
ANGT_CHICK  (P67885), ANGT_COTJA  (P67886), ANGT_HORSE  (P01016), 
ANGT_THETS  (Q10757), ANT3_CHICK  (Q03352), ANT3_MESAU  (P81050), 
SPI_HALRO   (Q10997)
» More

UniProtKB/Swiss-Prot
False positive sequences
107 sequences

ARLY_BUCAI  (P57159), AROB_BUCAI  (P57604), CADH2_DANRE (Q90275), 
CFT1_CANAL  (Q5AFT3), CH60_CUPPJ  (Q46XW6), CH60_MANSM  (Q65VE4), 
CH60_PLUGE  (O66194), CH60_PSEA6  (Q15PD3), CH60_RALME  (Q1LQS4), 
CH60_SHEB5  (A3D8W9), CH60_SHEB8  (A6WJ17), CH60_SHEDO  (Q12S61), 
CH60_SHEFN  (Q07WX7), CH60_SHEON  (Q8CX48), CH60_SHEPC  (A4Y398), 
CH60_SHESA  (A0L170), CH60_SHESM  (Q0HEQ4), CH60_SHESR  (Q0HZ97), 
CH60_SHESW  (A1RNN6), CHA4_YEAST  (P43634), CIDEC_HUMAN (Q96AQ7), 
CTR3_YEAST  (Q06686), DCL4_ORYSJ  (A7LFZ6), DISP1_MOUSE (Q3TDN0), 
DLG2_HUMAN  (Q15700), EFTU_LEPBY  (P50066), ENGB_EHRCJ  (Q3YS22), 
ERA_AGRT5   (Q8UGK1), ERA_BRUME   (Q8YG75), ERA_BRUSU   (Q8G1P9), 
ETCE_VIBPA  (Q87MW9), ETCE_VIBVU  (Q8D885), ETCE_VIBVY  (Q7MM86), 
FPG_PARUW   (Q6MCT3), HIR3_YEAST  (P47171), HTS1_COCCA  (Q01886), 
ICAC_STAA8  (Q9RQP6), ICAC_STAAM  (Q931E4), ICAC_STAAN  (Q7A348), 
ICAC_STAAR  (Q6GDD5), ICAC_STAAS  (Q6G605), ICAC_STAAW  (Q79ZV2), 
KS6A3_HUMAN (P51812), KS6A3_MOUSE (P18654), KS6A6_DANRE (Q6PFQ0), 
KS6A6_HUMAN (Q9UK32), KS6A6_MOUSE (Q7TPS0), LSPA_WOLSU  (Q7M9M1), 
MSH3_BOTFB  (A6RPB6), MSH3_SCLS1  (A7EC69), MURC_WOLTR  (Q5GTG5), 
NALP9_BOVIN (Q288C4), NHAA1_CAMJ8 (A8FNW6), NHAA1_CAMJD (A7H5Z9), 
NHAA1_CAMJE (Q0P7X4), NHAA1_CAMJJ (A1W1Q6), NHAA1_CAMJR (Q5HSD9), 
NU2M_PARTE  (P15577), NU4M_MYXGL  (Q9G2W9), NU6M_CHLRE  (P10329), 
PHNW_LYSSC  (B1HPR6), PLXC1_HUMAN (O60486), PLXC1_MOUSE (Q9QZC2), 
POMT2_HUMAN (Q9UKY4), POMT2_MOUSE (Q8BGQ4), RELE4_METJA (Q58573), 
RLMKL_IDILO (Q5QX63), RLMKL_PSEA6 (Q15UB5), S35F3_MOUSE (Q1LZI2), 
SID1_CAEEL  (Q9GZC8), SPNS3_MOUSE (Q9D232), SRB8_PICST  (A3GF47), 
STSY_RAUMA  (P68174), STSY_RAUSE  (P68175), SYA_BACAH   (A0RJ00), 
SYA_BACAN   (Q81LK0), SYA_BACC1   (P61697), SYA_BACCN   (A7GT67), 
SYA_BACCR   (Q817Z0), SYA_BACCZ   (Q634F6), SYA_BACHK   (Q6HDD7), 
SYA_BACLD   (Q65GS5), SYA_BACWK   (A9VI09), SYE1_CAMC5  (A7GXI1), 
SYI_ANTLO   (Q27707), TERT_ARATH  (Q9SPU7), TOLB_CAMJE  (Q9PJ14), 
TOLB_CAMJR  (Q5HX54), TOLB_HELPH  (Q1CSE0), TOLB_HELPJ  (Q9ZK86), 
TOLB_HELPY  (O25751), TPN50_TREPA (P38369), UL79_SHV21  (Q01003), 
UNC5D_HUMAN (Q6UXZ4), UNC5D_MOUSE (Q8K1S2), UVRC_WOLTR  (Q5GSR4), 
VL3_HPV5B   (P26541), Y3085_AZOC5 (Q04855), Y3264_ARATH (P0C897), 
Y3311_PSEAE (Q9HYT3), YCF1A_MARPO (P12221), YHJN_BACSU  (O07568), 
YHS4_SCHPO  (Q874R4), YIDC_STRAW  (P59811), YIDC_STRCO  (O54569), 
YQOA_CAEEL  (Q09299), ZDHC5_DICDI (Q554E7)
» More

PDB
[Detailed view]
127 PDB

1A7C; 1ANT; 1AS4; 1ATH; 1ATT; 1ATU; 1AZX; 1B3K; 1BR8; 1BY7; 1C5G; 1C8O; 1D5S; 1DB2; 1DVM; 1DVN; 1DZG; 1DZH; 1E03; 1E04; 1E05; 1EZX; 1F0C; 1HLE; 1HP7; 1IMV; 1JJO; 1JMJ; 1JMO; 1JRR; 1JTI; 1JVQ; 1K9O; 1KCT; 1LJ5; 1LK6; 1LQ8; 1M93; 1NQ9; 1OC0; 1OO8; 1OPH; 1OVA; 1OYH; 1PSI; 1QLP; 1QMN; 1R1L; 1SEK; 1SR5; 1T1F; 1TB6; 1UHG; 1WZ9; 1XQG; 1XQJ; 1XU8; 1YXA; 2ACH; 2ANT; 2ARQ; 2ARR; 2B4X; 2B5T; 2BEH; 2CEO; 2D26; 2GD4; 2HI9; 2HIJ; 2OAY; 2OL2; 2QUG; 2R9Y; 2RIV; 2RIW; 2V95; 2VDX; 2VDY; 2WXW; 2X0B; 2XN3; 2XN5; 2XN6; 2XN7; 2ZNH; 2ZV6; 3B9F; 3CAA; 3CVM; 3CWL; 3CWM; 3DRM; 3DRU; 3DY0; 3EOX; 3EVJ; 3F02; 3F5N; 3FGQ; 3KCG; 3LE2; 3LW2; 3NDD; 3NDF; 3NE4; 3PB1; 3Q02; 3Q03; 3R4L; 3T1P; 3UT3; 3VVJ; 4AQH; 4BB2; 4CAA; 4DY0; 4DY7; 4EB1; 4G8O; 4G8R; 4GA7; 4IC0; 7API; 8API; 9API; 9PAI
» More

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