Entry: PS00288

General information about the entry

Entry name [info] TIMP
Accession [info] PS00288
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); JUL-1999 (DATA UPDATE); APR-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00260

Name and characterization of the entry

Description [info] Tissue inhibitors of metalloproteinases signature.
Pattern [info]

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_06 which contains 548'586 sequence entries.

Total number of hits 33 in 33 different sequences
Number of true positive hits 33 in 33 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 4
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 89.19 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

True positive sequences
33 sequences

TIMP1_BOVIN (P20414), TIMP1_HORSE (O02722), TIMP1_HUMAN (P01033), 
TIMP1_MOUSE (P12032), TIMP1_PAPCY (P49061), TIMP1_PIG   (P35624), 
TIMP1_PONAB (Q5RC60), TIMP1_RABIT (P20614), TIMP1_RAT   (P30120), 
TIMP1_SHEEP (P50122), TIMP2_BOVIN (P16368), TIMP2_CANFA (Q9TTY1), 
TIMP2_CAVPO (Q9WUC6), TIMP2_CHICK (O42146), TIMP2_CRILO (Q60453), 
TIMP2_HUMAN (P16035), TIMP2_MOUSE (P25785), TIMP2_RABIT (Q9TRZ7), 
TIMP2_RAT   (P30121), TIMP3_BOVIN (P79121), TIMP3_CHICK (P26652), 
TIMP3_HORSE (Q9TUL9), TIMP3_HUMAN (P35625), TIMP3_MACFA (P61269), 
TIMP3_MACMU (Q5PXZ9), TIMP3_MOUSE (P39876), TIMP3_RAT   (P48032), 
TIMP3_SCYTO (Q9W6B4), TIMP3_XENLA (O73746), TIMP4_BOVIN (O97563), 
TIMP4_HUMAN (Q99727), TIMP4_MOUSE (Q9JHB3), TIMP4_RAT   (P81556)
» More

False negative sequences
4 sequences

TIMP1_CANFA (P81546), TIMP1_MACMU (Q95KL9), TIMPL_CAEEL (Q21265), 
» More

'Partial' sequences
2 sequences

TIMP3_RABIT (O97590), TIMP4_RABIT (O97591)

[Detailed view]
14 PDB

1BQQ; 1BR9; 1BUV; 1D2B; 1GXD; 1OO9; 1UEA; 2E2D; 2J0T; 2TMP; 3CKI; 3MA2; 3V96; 4ILW
» More

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