Entry: PS00288

General information about the entry

Entry name [info] TIMP
Accession [info] PS00288
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); JUL-1999 (DATA UPDATE); MAR-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00260

Name and characterization of the entry

Description [info] Tissue inhibitors of metalloproteinases signature.
Pattern [info]

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_04 which contains 550'960 sequence entries.

Total number of hits 33 in 33 different sequences
Number of true positive hits 33 in 33 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 89.19 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

True positive sequences
33 sequences

TIMP1_BOVIN (P20414), TIMP1_HORSE (O02722), TIMP1_HUMAN (P01033), 
TIMP1_MOUSE (P12032), TIMP1_PAPCY (P49061), TIMP1_PIG   (P35624), 
TIMP1_PONAB (Q5RC60), TIMP1_RABIT (P20614), TIMP1_RAT   (P30120), 
TIMP1_SHEEP (P50122), TIMP2_BOVIN (P16368), TIMP2_CANLF (Q9TTY1), 
TIMP2_CAVPO (Q9WUC6), TIMP2_CHICK (O42146), TIMP2_CRILO (Q60453), 
TIMP2_HUMAN (P16035), TIMP2_MOUSE (P25785), TIMP2_RABIT (Q9TRZ7), 
TIMP2_RAT   (P30121), TIMP3_BOVIN (P79121), TIMP3_CHICK (P26652), 
TIMP3_HORSE (Q9TUL9), TIMP3_HUMAN (P35625), TIMP3_MACFA (P61269), 
TIMP3_MACMU (Q5PXZ9), TIMP3_MOUSE (P39876), TIMP3_RAT   (P48032), 
TIMP3_SCYTO (Q9W6B4), TIMP3_XENLA (O73746), TIMP4_BOVIN (O97563), 
TIMP4_HUMAN (Q99727), TIMP4_MOUSE (Q9JHB3), TIMP4_RAT   (P81556)
» more

False negative sequences
4 sequences

TIMP1_CANLF (P81546), TIMP1_MACMU (Q95KL9), TIMPL_CAEEL (Q21265), 
» more

'Partial' sequences
2 sequences

TIMP3_RABIT (O97590), TIMP4_RABIT (O97591)

[Detailed view]
14 PDB

1BQQ; 1BR9; 1BUV; 1D2B; 1GXD; 1OO9; 1UEA; 2E2D; 2J0T; 2TMP; 3CKI; 3MA2; 3V96; 4ILW
» more

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