PROSITE entry PS00303

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General information about the entry

Entry name [info]	S100_CABP
Accession [info]	PS00303
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00275

Name and characterization of the entry

Description [info]	S-100/ICaBP type calcium binding protein signature.
Pattern [info]	[LIVMFYW](2)-x(2)-[LKQ]-D-x(3)-[DN]-x(3)-[DNSG]-[FY]-x-[ES]-[FYVC]-x(2)- [LIVMFS]-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.

Total number of hits	93 in 93 different sequences
Number of true positive hits	86 in 86 different sequences
Number of 'unknown' hits	0
Number of false positive hits	7 in 7 different sequences
Number of false negative sequences	14
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	92.47 %
Recall (true positives / (true positives + false negatives))	86.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	86 sequences CML45_ARATH (Q9MBG5), FILA2_HUMAN (Q5D862), FILA2_MOUSE (Q2VIS4), FILA_HUMAN (P20930), HORN_HUMAN (Q86YZ3), HORN_MOUSE (Q8VHD8), M126_CHICK (P28318), RPTN_HUMAN (Q6XPR3), RPTN_MOUSE (P97347), S100B_BOVIN (P02638), S100B_HUMAN (P04271), S100B_MOUSE (P50114), S100B_RABIT (Q6YNR6), S100B_RAT (P04631), S100G_BOVIN (P02633), S100G_HORSE (Q865V3), S100G_HUMAN (P29377), S100G_MOUSE (P97816), S100G_PIG (P02632), S100G_RAT (P02634), S100P_HUMAN (P25815), S100Z_DANRE (Q503K9), S100Z_HUMAN (Q8WXG8), S10A1_BOVIN (P02639), S10A1_HUMAN (P23297), S10A1_MISFO (Q7LZT1), S10A1_MOUSE (P56565), S10A1_PONAB (Q5RC36), S10A1_RAT (P35467), S10A2_BOVIN (P10462), S10A2_HUMAN (P29034), S10A3_HUMAN (P33764), S10A3_MOUSE (P62818), S10A3_RAT (P62819), S10A4_BOVIN (P35466), S10A4_CANLF (Q9TV56), S10A4_HUMAN (P26447), S10A4_MOUSE (P07091), S10A4_RAT (P05942), S10A5_HUMAN (P33763), S10A5_MOUSE (P63084), S10A5_RAT (P63083), S10A6_CHICK (Q98953), S10A6_HORSE (O77691), S10A6_HUMAN (P06703), S10A6_MOUSE (P14069), S10A6_PIG (Q2EN75), S10A6_RABIT (P30801), S10A6_RAT (P05964), S10A7_BOVIN (Q28050), S10A7_HORSE (Q14ST5), S10A7_HUMAN (P31151), S10A8_BOVIN (P28782), S10A8_HUMAN (P05109), S10A8_MOUSE (P27005), S10A8_RAT (P50115), S10A9_BOVIN (P28783), S10A9_HUMAN (P06702), S10A9_MOUSE (P31725), S10A9_RABIT (P50117), S10A9_RAT (P50116), S10AA_BOVIN (P60902), S10AA_CHICK (P27003), S10AA_HUMAN (P60903), S10AA_MACMU (P62504), S10AA_MOUSE (P08207), S10AA_PIG (P04163), S10AA_RABIT (Q6SQH4), S10AA_RAT (P05943), S10AB_CHICK (P24479), S10AB_HUMAN (P31949), S10AB_MOUSE (P50543), S10AB_PIG (P31950), S10AB_RABIT (P24480), S10AB_RAT (Q6B345), S10AC_BOVIN (P79105), S10AC_HUMAN (P80511), S10AC_PIG (P80310), S10AC_RABIT (O77791), S10AG_BOVIN (Q0VCM0), S10AG_HUMAN (Q96FQ6), S10I_ICTPU (Q91061), S1A7A_HUMAN (Q86SG5), TRHY_HUMAN (Q07283), TRHY_RABIT (P37709), TRHY_SHEEP (P22793) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	14 sequences S10AA_XENLA (P27004), S10AD_BOVIN (P79342), S10AD_HUMAN (Q99584), S10AD_MOUSE (P97352), S10AE_BOVIN (Q3MHP3), S10AE_HUMAN (Q9HCY8), S10AE_MOUSE (Q9D2Q8), S115A_GORGO (A7K6Y8), S115A_MOUSE (Q6S5I3), S115A_PONAB (A7K6Y9), S1A7B_HUMAN (Q5SY68), TCHL1_BOVIN (A6QP92), TCHL1_HUMAN (Q5QJ38), TCHL1_MOUSE (Q9D3P1) » more
UniProtKB/Swiss-Prot False positive sequences	7 sequences CABP7_HUMAN (Q86V35), CABP7_MOUSE (Q91ZM8), CABP7_PAPAN (Q866X0), CABP7_RAT (Q66H96), CABP8_HUMAN (Q9BXU9), CABP8_MOUSE (Q9JJG7), CABP8_RAT (Q06BI3) » more
PDB [Detailed view]	173 PDB 1A03; 1A4P; 1B1G; 1B4C; 1BOC; 1BOD; 1BT6; 1CB1; 1CDN; 1CFP; 1CLB; 1CNP; 1D1O; 1DT7; 1E8A; 1GQM; 1HT9; 1IG5; 1IGV; 1IRJ; 1J55; 1JWD; 1K2H; 1K8U; 1K96; 1K9K; 1K9P; 1KCY; 1KQV; 1KSM; 1KSO; 1M31; 1MHO; 1MQ1; 1MR8; 1MWN; 1N65; 1NSH; 1ODB; 1OZO; 1PSB; 1PSR; 1QLK; 1QLS; 1SYM; 1UWO; 1XK4; 1XYD; 1ZFS; 2BCA; 2BCB; 2CNP; 2H61; 2JPT; 2JTT; 2K2F; 2K7O; 2KAX; 2KAY; 2KBM; 2L0P; 2L50; 2L51; 2LHL; 2LLS; 2LLT; 2LLU; 2LNK; 2LP2; 2LP3; 2LUC; 2LUX; 2M1K; 2M3W; 2M49; 2M9G; 2MAZ; 2MJW; 2MRD; 2PRU; 2PSR; 2Q91; 2RGI; 2WC8; 2WCB; 2WCE; 2WCF; 2WND; 2WOR; 2WOS; 2Y5I; 3C1V; 3CGA; 3CR2; 3CR4; 3CR5; 3CZT; 3D0Y; 3D10; 3GK1; 3GK2; 3GK4; 3HCM; 3ICB; 3IQO; 3IQQ; 3KO0; 3LK0; 3LK1; 3LLE; 3M0W; 3NSI; 3NSK; 3NSL; 3NSO; 3NXA; 3PSR; 3RLZ; 3RM1; 3ZWH; 4AQI; 4AQJ; 4CFQ; 4CFR; 4DIR; 4DRW; 4DUQ; 4ETO; 4FQO; 4FTG; 4GGF; 4HRE; 4HRG; 4HRH; 4HSZ; 4ICB; 4P2Y; 4PCW; 4PDZ; 4PE0; 4PE1; 4PE4; 4PE7; 4XJK; 4XYN; 4YBH; 5CSF; 5CSI; 5CSJ; 5CSN; 5D7F; 5DKN; 5DKQ; 5DKR; 5ER4; 5ER5; 5HLO; 5HLV; 5HYD; 5I8N; 5K89; 5LPU; 5W1F; 6DS2; 6T58; 6WN7; 6ZDY; 7NMI; 7PSP; 7PSQ; 7QUV; 7UI5; 8FJ8 » more