Entry: PS00318

General information about the entry

Entry name [info] HMG_COA_REDUCTASE_2
Accession [info] PS00318
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-1990 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00064

Name and characterization of the entry

Description [info] Hydroxymethylglutaryl-coenzyme A reductases signature 2.
Pattern [info]
[LIVM]-G-x-[LIVM]-G-G-[AG]-T.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_08 which contains 551'987 sequence entries.


Total number of hits 81 in 81 different sequences
Number of true positive hits 56 in 56 different sequences
Number of 'unknown' hits 0
Number of false positive hits 25 in 25 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 69.14 %
Recall (true positives / (true positives + false negatives)) 96.55 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
56 sequences

HMDH1_ARATH (P14891    ), HMDH1_DICDI (P34135    ), HMDH1_GOSHI (O64966    ), 
HMDH1_HEVBR (P29057    ), HMDH1_ORYSI (A2X8W3    ), HMDH1_ORYSJ (Q0DY59    ), 
HMDH1_SOLTU (P48020    ), HMDH1_YEAST (P12683    ), HMDH2_ARATH (P43256    ), 
HMDH2_CAPAN (Q9XEL8    ), HMDH2_DICDI (P34136    ), HMDH2_GOSHI (O64967    ), 
HMDH2_HEVBR (P29058    ), HMDH2_SOLLC (P48022    ), HMDH2_SOLTU (Q41437    ), 
HMDH2_YEAST (P12684    ), HMDH3_HEVBR (Q00583    ), HMDH3_ORYSJ (Q9XHL5    ), 
HMDH3_SOLTU (Q41438    ), HMDH_AERPE  (Q9YAS4    ), HMDH_AGRIP  (O76819    ), 
HMDH_ARCFU  (O28538    ), HMDH_ASPTE  (Q9Y7D2    ), HMDH_ASPTN  (Q0C8L9    ), 
HMDH_BLAGE  (P54960    ), HMDH_BOVIN  (A7Z064    ), HMDH_CAMAC  (P48021    ), 
HMDH_CATRO  (Q03163    ), HMDH_CRIGR  (P00347    ), HMDH_CYBJA  (O74164    ), 
HMDH_DROME  (P14773    ), HMDH_GIBF5  (S0DQM8    ), HMDH_GIBFU  (P0CT44    ), 
HMDH_HALS3  (B0R6J9    ), HMDH_HALVD  (Q59468    ), HMDH_HUMAN  (P04035    ), 
HMDH_MAIZE  (O24594    ), HMDH_MESAU  (P09610    ), HMDH_METJA  (Q58116    ), 
HMDH_MOUSE  (Q01237    ), HMDH_NICSY  (Q01559    ), HMDH_PHYB8  (Q12649    ), 
HMDH_PIG    (Q1W675    ), HMDH_PONAB  (Q5R6N3    ), HMDH_PYRAB  (Q9V1R3    ), 
HMDH_PYRHO  (O59469    ), HMDH_RABIT  (Q29512    ), HMDH_RAT    (P51639    ), 
HMDH_SCHMA  (P16237    ), HMDH_SCHPO  (Q10283    ), HMDH_STRPU  (P16393    ), 
HMDH_SULSO  (O08424    ), HMDH_XENLA  (P20715    ), MLCD_PENCI  (Q8J0F4    ), 
MOKG_MONPI  (Q3S2U3    ), MVAA_PSEMV  (P13702    )
» more

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

HMDH_BORBU  (O51628    ), HMDH_METTH  (O26662    )

		
UniProtKB/Swiss-Prot
False positive sequences
25 sequences

AMIC_STRPN  (P0A4M7    ), AMIC_STRR6  (P0A4M8    ), ARO1_SCLS1  (A7F7H0    ), 
ARO1_SCLSC  (Q5XNP0    ), C3390_DROME (Q7KT91    ), CDX4_HUMAN  (O14627    ), 
CND1_MOUSE  (Q8K2Z4    ), DHOM_METGL  (P37143    ), DHOM_PSEAE  (P29365    ), 
DHON_METGL  (P37144    ), GBA2_HUMAN  (Q9HCG7    ), GBA2_MOUSE  (Q69ZF3    ), 
GBA2_RAT    (Q5M868    ), INIB_MYCTO  (P9WJ96    ), INIB_MYCTU  (P9WJ97    ), 
MSRA_LACSA  (Q9SEC2    ), MURC_ERYLH  (Q2NCY9    ), NU4C_SYNPW  (A5GP41    ), 
SECY_METJA  (Q60175    ), SIGJ_DICDI  (Q6TMJ3    ), SYYM_ARATH  (Q9M876    ), 
SYY_MESFL   (Q6F0M8    ), SYY_STRAW   (Q829F2    ), THIM_DESDA  (B8J4C1    ), 
Y3023_ACIAD (P70736    )
» more

PDB
[Detailed view]
33 PDB

1DQ8; 1DQ9; 1DQA; 1HW8; 1HW9; 1HWI; 1HWJ; 1HWK; 1HWL; 1QAX; 1QAY; 1R31; 1R7I; 1T02; 2Q1L; 2Q6B; 2Q6C; 2R4F; 3BGL; 3CCT; 3CCW; 3CCZ; 3CD0; 3CD5; 3CD7; 3CDA; 3CDB; 4I4B; 4I56; 4I64; 4I6A; 4I6W; 4I6Y
» more

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