Entry: PS00338

Forthcoming changes to the profile format
General information about the entry

Entry name [info] SOMATOTROPIN_2
Accession [info] PS00338
Entry type [info] PATTERN
Date [info] APR-1990 (CREATED); APR-2006 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00239

Name and characterization of the entry

Description [info] Somatotropin, prolactin and related hormones signature 2.
Pattern [info]
C-[LIVMFY]-{PT}-x-D-[LIVMFYSTA]-x-{S}-{RK}-{A}-x-[LIVMFY]-x(2)-[LIVMFYT]-
x(2)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_08 which contains 546'238 sequence entries.


Total number of hits 212 in 212 different sequences
Number of true positive hits 194 in 194 different sequences
Number of 'unknown' hits
Number of false positive hits 18 in 18 different sequences
Number of false negative sequences 22
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 91.51 %
Recall (true positives / (true positives + false negatives)) 89.81 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 16
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
194 sequences

CSH1_BOVIN  (P09611), CSH1_HUMAN  (P0DML2), CSH2_BOVIN  (P19159), 
CSH2_HUMAN  (P0DML3), CSHL_HUMAN  (Q14406), CSH_SHEEP   (P16038), 
PLRP1_BOVIN (P05402), PLRP2_BOVIN (P12401), PLRP3_BOVIN (P12402), 
PLRP4_BOVIN (P18917), PR2C2_MOUSE (P04095), PR2C3_MOUSE (P04768), 
PR3B1_MESAU (P14059), PR3B1_MOUSE (P09586), PR3B1_RAT   (P09321), 
PR3D1_MOUSE (P18121), PR3D1_RAT   (P21702), PR3D4_RAT   (P34207), 
PR4A1_MOUSE (O35256), PR4A1_RAT   (P09320), PR7A1_MOUSE (O54830), 
PR7A2_MOUSE (O54831), PR7A2_RAT   (Q9R006), PR7C1_MOUSE (Q9CRB5), 
PR7D1_MOUSE (P04769), PR8A5_RAT   (P33579), PRL1_ONCKE  (P69130), 
PRL1_ONCTS  (P69131), PRL1_OREMO  (P09319), PRL2_ONCKE  (P09584), 
PRL2_ONCTS  (Q91364), PRL2_OREMO  (P09318), PRL_AILME   (Q8HXS1), 
PRL_ANGAN   (P33096), PRL_ANGJA   (Q7ZZV3), PRL_BALBO   (P33089), 
PRL_BOVIN   (P01239), PRL_BUFJA   (P43001), PRL_CAMDR   (P22393), 
PRL_CAPHI   (Q28318), PRL_CARAU   (P87495), PRL_CEREL   (Q6UC74), 
PRL_CHEMY   (P33090), PRL_CHICK   (P14676), PRL_CORAU   (P34181), 
PRL_CYPCA   (P09585), PRL_DICLA   (P48249), PRL_FELCA   (P46403), 
PRL_HORSE   (P12420), PRL_HUMAN   (P01236), PRL_HYPMO   (P35395), 
PRL_HYPNO   (P29235), PRL_ICTPU   (P51904), PRL_ISOMA   (Q3Y4G6), 
PRL_LOXAF   (P10765), PRL_MACMU   (P55151), PRL_MELGA   (P17572), 
PRL_MESAU   (P37884), PRL_MICMO   (Q9QZL1), PRL_MONDO   (O62819), 
PRL_MOUSE   (P06879), PRL_NEOVI   (P29234), PRL_ONCMY   (P21993), 
PRL_PAROL   (Q9YGV6), PRL_PIG     (P01238), PRL_PROAT   (P33091), 
PRL_RABIT   (Q28632), PRL_RAT     (P01237), PRL_SALSA   (P48096), 
PRL_SHEEP   (P01240), PRL_SPAAU   (O93337), PRL_TRIVU   (O62781), 
SOM2_HUMAN  (P01242), SOM2_MACMU  (Q07370), SOM2_PANTR  (P58757), 
SOMA1_ACIGU (P26773), SOMA1_CARAU (O93359), SOMA1_ONCMY (P09538), 
SOMA1_ONCNE (Q91222), SOMA1_XENLA (P12855), SOMA2_ACIGU (P26774), 
SOMA2_CARAU (O93360), SOMA2_ONCMY (P20332), SOMA2_ONCNE (Q91221), 
SOMA2_XENLA (P12856), SOMA_ACABU  (Q01282), SOMA_ACALA  (P45654), 
SOMA_AILME  (Q8HYE5), SOMA_ANAPL  (P11228), SOMA_ANGJA  (P08899), 
SOMA_BALBO  (P33092), SOMA_BALPH  (Q659Q8), SOMA_BOSGF  (Q1HFN3), 
SOMA_BOSMU  (Q864S7), SOMA_BOVIN  (P01246), SOMA_BUBBU  (O18938), 
SOMA_BUFMA  (O73849), SOMA_CALJA  (Q9GMB3), SOMA_CAMDR  (Q7YRR6), 
SOMA_CANFA  (P33711), SOMA_CAPHI  (P67931), SOMA_CAVPO  (Q9JKM4), 
SOMA_CEREL  (P56437), SOMA_CHEMY  (P34005), SOMA_CHICK  (P08998), 
SOMA_CORAU  (P45655), SOMA_CORLV  (O13188), SOMA_CRONO  (P55755), 
SOMA_CTEID  (P69158), SOMA_CYPCA  (P10298), SOMA_DELDE  (Q8MI73), 
SOMA_DICLA  (Q05163), SOMA_ESOLU  (P34744), SOMA_FELCA  (P46404), 
SOMA_GALSE  (Q9GKA1), SOMA_GIRCA  (Q7YQD2), SOMA_HETFO  (Q9W6R8), 
SOMA_HIPAM  (Q7YQB8), SOMA_HORSE  (P01245), SOMA_HUMAN  (P01241), 
SOMA_HYPMO  (P69159), SOMA_HYPNO  (P69160), SOMA_ICTPU  (P34745), 
SOMA_KATPE  (P20391), SOMA_LABRO  (Q9W6J7), SOMA_LARCR  (Q9I9M4), 
SOMA_LATCA  (Q01283), SOMA_LEPOS  (P79885), SOMA_LITCT  (P10813), 
SOMA_LOXAF  (P20392), SOMA_MACMU  (P33093), SOMA_MELGA  (P22077), 
SOMA_MESAU  (P37886), SOMA_MISMI  (Q9W6J5), SOMA_MONDO  (Q9GL60), 
SOMA_MORSA  (P48248), SOMA_MOUSE  (P06880), SOMA_NEOVI  (P19795), 
SOMA_NYCPY  (Q9GMB2), SOMA_ODOAR  (Q9I9L5), SOMA_ONCKE  (P07064), 
SOMA_ONCKI  (P10607), SOMA_ONCMA  (Q9DGG5), SOMA_ONCTS  (Q07221), 
SOMA_OREMO  (P34746), SOMA_ORENI  (P13391), SOMA_PAGMA  (P08591), 
SOMA_PANGG  (P69162), SOMA_PANPG  (P69161), SOMA_PANTR  (P58756), 
SOMA_PAROL  (P09537), SOMA_PERFV  (Q9DEV3), SOMA_PIG    (P01248), 
SOMA_PRIGL  (P34006), SOMA_PROAN  (O73848), SOMA_PSEDN  (P24363), 
SOMA_RABIT  (P46407), SOMA_RAT    (P01244), SOMA_SAIBB  (P58343), 
SOMA_SALSA  (P10814), SOMA_SCIOC  (Q9IB11), SOMA_SEBSC  (P87391), 
SOMA_SERQU  (P09539), SOMA_SHEEP  (P67930), SOMA_SIGGU  (Q9IBE5), 
SOMA_SOLSE  (P45643), SOMA_SPAAU  (P29971), SOMA_SPAEH  (O70615), 
SOMA_STRCA  (Q9PWG3), SOMA_TAKRU  (O12980), SOMA_THUAL  (P34747), 
SOMA_THUTH  (P09113), SOMA_TRITC  (Q98UF6), SOMA_TRIVU  (O62754), 
SOMA_VERVA  (O93566), SOMA_VICPA  (P37885), SOMA_VULVU  (P10766), 
SOML1_SPAAU (P54863), SOML2_SPAAU (P79894), SOML_ACITR  (O93262), 
SOML_ANGAN  (Q90216), SOML_CARAU  (P79697), SOML_CYCLU  (P45640), 
SOML_GADMO  (P21919), SOML_HIPHI  (P45641), SOML_ICTPU  (Q9I8J9), 
SOML_ONCKE  (P24405), SOML_ORYLA  (Q6E211), SOML_PAROL  (P20362), 
SOML_PROAN  (O73847), SOML_SCIOC  (Q9YGK7), SOML_SIGGU  (Q9PWG4), 
SOML_SOLSE  (P45642), SOML_TETMU  (Q9I9H4)
» More

UniProtKB/Swiss-Prot
False negative sequences
22 sequences

PR2A1_MOUSE (Q9JHK0), PR2A1_RAT   (Q9JII3), PR2B1_MOUSE (Q9DAZ2), 
PR2B1_RAT   (Q9JKL9), PR3C1_MOUSE (Q9QUN5), PR3C1_RAT   (Q9QUL0), 
PR5A1_MOUSE (Q9JII2), PR5A1_RAT   (Q9JII4), PR6A1_MOUSE (O35257), 
PR6A1_RAT   (P24800), PR7B1_MOUSE (Q8CGZ9), PR7B1_RAT   (Q8CJ42), 
PR8A4_RAT   (P33580), PR8A6_MOUSE (Q9DAY2), PR8A7_RAT   (P33578), 
PR8A8_MOUSE (Q9DAS4), PR8A9_MOUSE (Q9CQ58), PR8A9_RAT   (Q920I0), 
PRL1_ALLMI  (P55751), PRL1_CRONO  (P55753), PRL2_ALLMI  (P55752), 
PRL2_CRONO  (P55754)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

GHR4_RAT    (P33581)

		
UniProtKB/Swiss-Prot
False positive sequences
18 sequences

ALA2_ARATH  (P98205), CD3E_PIG    (Q7YRN2), ENV_FFV     (O56861), 
ENV_HV2EH   (Q89607), ENV_HV2UC   (Q76638), ENV_SFV1    (P23073), 
ENV_SFV3L   (P27399), GRT1A_DANRE (Q6PBU5), GRTP1_HUMAN (Q5TC63), 
GRTP1_MOUSE (Q9D3N8), GRTP1_RAT   (Q4QQU7), GRTP1_XENLA (Q6GLZ0), 
GRTP1_XENTR (Q6GL87), ODB2_CAEEL  (Q23571), PP341_ARATH (Q9SUH6), 
ZFHX4_CHICK (O73590), ZFHX4_HUMAN (Q86UP3), ZFHX4_MOUSE (Q9JJN2)
» More

PDB
[Detailed view]
22 PDB

1A22; 1BP3; 1F6F; 1HGU; 1HUW; 1HWG; 1HWH; 1KF9; 1RW5; 1Z7C; 2Q98; 3D48; 3EW3; 3HHR; 3MZG; 3N06; 3N0P; 3NCB; 3NCC; 3NCE; 3NCF; 3NPZ
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission