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Entry: PS00338

General information about the entry

Entry name [info] SOMATOTROPIN_2
Accession [info] PS00338
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00239

Name and characterization of the entry

Description [info] Somatotropin, prolactin and related hormones signature 2.
Pattern [info]
C-[LIVMFY]-{PT}-x-D-[LIVMFYSTA]-x-{S}-{RK}-{A}-x-[LIVMFY]-x(2)-[LIVMFYT]-
x(2)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 213 in 213 different sequences
Number of true positive hits 195 in 195 different sequences
Number of 'unknown' hits 0
Number of false positive hits 18 in 18 different sequences
Number of false negative sequences 22
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 91.55 %
Recall (true positives / (true positives + false negatives)) 89.86 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 16
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
195 sequences

CSH1_BOVIN  (P09611    ), CSH1_HUMAN  (P0DML2    ), CSH2_BOVIN  (P19159    ), 
CSH2_HUMAN  (P0DML3    ), CSHL_HUMAN  (Q14406    ), CSH_SHEEP   (P16038    ), 
PLRP1_BOVIN (P05402    ), PLRP2_BOVIN (P12401    ), PLRP3_BOVIN (P12402    ), 
PLRP4_BOVIN (P18917    ), PR2C2_MOUSE (P04095    ), PR2C3_MOUSE (P04768    ), 
PR2C5_MOUSE (Q9JLV9    ), PR3B1_MESAU (P14059    ), PR3B1_MOUSE (P09586    ), 
PR3B1_RAT   (P09321    ), PR3D1_MOUSE (P18121    ), PR3D1_RAT   (P21702    ), 
PR3D4_RAT   (P34207    ), PR4A1_MOUSE (O35256    ), PR4A1_RAT   (P09320    ), 
PR7A1_MOUSE (O54830    ), PR7A2_MOUSE (O54831    ), PR7A2_RAT   (Q9R006    ), 
PR7C1_MOUSE (Q9CRB5    ), PR7D1_MOUSE (P04769    ), PR8A5_RAT   (P33579    ), 
PRL1_ONCKE  (P69130    ), PRL1_ONCTS  (P69131    ), PRL1_OREMO  (P09319    ), 
PRL2_ONCKE  (P09584    ), PRL2_ONCTS  (Q91364    ), PRL2_OREMO  (P09318    ), 
PRL_AILME   (Q8HXS1    ), PRL_ANGAN   (P33096    ), PRL_ANGJA   (Q7ZZV3    ), 
PRL_BALBO   (P33089    ), PRL_BOVIN   (P01239    ), PRL_BUFJA   (P43001    ), 
PRL_CAMDR   (P22393    ), PRL_CAPHI   (Q28318    ), PRL_CARAU   (P87495    ), 
PRL_CEREL   (Q6UC74    ), PRL_CHEMY   (P33090    ), PRL_CHICK   (P14676    ), 
PRL_CORAU   (P34181    ), PRL_CYPCA   (P09585    ), PRL_DICLA   (P48249    ), 
PRL_FELCA   (P46403    ), PRL_HORSE   (P12420    ), PRL_HUMAN   (P01236    ), 
PRL_HYPMO   (P35395    ), PRL_HYPNO   (P29235    ), PRL_ICTPU   (P51904    ), 
PRL_ISOMA   (Q3Y4G6    ), PRL_LOXAF   (P10765    ), PRL_MACMU   (P55151    ), 
PRL_MELGA   (P17572    ), PRL_MESAU   (P37884    ), PRL_MICMO   (Q9QZL1    ), 
PRL_MONDO   (O62819    ), PRL_MOUSE   (P06879    ), PRL_NEOVI   (P29234    ), 
PRL_ONCMY   (P21993    ), PRL_PAROL   (Q9YGV6    ), PRL_PIG     (P01238    ), 
PRL_PROAT   (P33091    ), PRL_RABIT   (Q28632    ), PRL_RAT     (P01237    ), 
PRL_SALSA   (P48096    ), PRL_SHEEP   (P01240    ), PRL_SPAAU   (O93337    ), 
PRL_TRIVU   (O62781    ), SOM2_HUMAN  (P01242    ), SOM2_MACMU  (Q07370    ), 
SOM2_PANTR  (P58757    ), SOMA1_ACIGU (P26773    ), SOMA1_CARAU (O93359    ), 
SOMA1_ONCMY (P09538    ), SOMA1_ONCNE (Q91222    ), SOMA1_XENLA (P12855    ), 
SOMA2_ACIGU (P26774    ), SOMA2_CARAU (O93360    ), SOMA2_ONCMY (P20332    ), 
SOMA2_ONCNE (Q91221    ), SOMA2_XENLA (P12856    ), SOMA_ACABU  (Q01282    ), 
SOMA_ACALA  (P45654    ), SOMA_AILME  (Q8HYE5    ), SOMA_ANAPL  (P11228    ), 
SOMA_ANGJA  (P08899    ), SOMA_BALBO  (P33092    ), SOMA_BALPH  (Q659Q8    ), 
SOMA_BOSGF  (Q1HFN3    ), SOMA_BOSMU  (Q864S7    ), SOMA_BOVIN  (P01246    ), 
SOMA_BUBBU  (O18938    ), SOMA_CALJA  (Q9GMB3    ), SOMA_CAMDR  (Q7YRR6    ), 
SOMA_CANLF  (P33711    ), SOMA_CAPHI  (P67931    ), SOMA_CAVPO  (Q9JKM4    ), 
SOMA_CEREL  (P56437    ), SOMA_CHEMY  (P34005    ), SOMA_CHICK  (P08998    ), 
SOMA_CORAU  (P45655    ), SOMA_CORLV  (O13188    ), SOMA_CRONO  (P55755    ), 
SOMA_CTEID  (P69158    ), SOMA_CYPCA  (P10298    ), SOMA_DELDE  (Q8MI73    ), 
SOMA_DICLA  (Q05163    ), SOMA_ESOLU  (P34744    ), SOMA_FELCA  (P46404    ), 
SOMA_GALSE  (Q9GKA1    ), SOMA_GIRCA  (Q7YQD2    ), SOMA_HETFO  (Q9W6R8    ), 
SOMA_HIPAM  (Q7YQB8    ), SOMA_HORSE  (P01245    ), SOMA_HUMAN  (P01241    ), 
SOMA_HYPMO  (P69159    ), SOMA_HYPNO  (P69160    ), SOMA_ICTPU  (P34745    ), 
SOMA_KATPE  (P20391    ), SOMA_LABRO  (Q9W6J7    ), SOMA_LARCR  (Q9I9M4    ), 
SOMA_LATCA  (Q01283    ), SOMA_LEPOS  (P79885    ), SOMA_LITCT  (P10813    ), 
SOMA_LOXAF  (P20392    ), SOMA_MACMU  (P33093    ), SOMA_MELGA  (P22077    ), 
SOMA_MESAU  (P37886    ), SOMA_MISMI  (Q9W6J5    ), SOMA_MONDO  (Q9GL60    ), 
SOMA_MORSA  (P48248    ), SOMA_MOUSE  (P06880    ), SOMA_NEOVI  (P19795    ), 
SOMA_NYCPY  (Q9GMB2    ), SOMA_ODOAR  (Q9I9L5    ), SOMA_ONCKE  (P07064    ), 
SOMA_ONCKI  (P10607    ), SOMA_ONCMA  (Q9DGG5    ), SOMA_ONCTS  (Q07221    ), 
SOMA_OREMO  (P34746    ), SOMA_ORENI  (P13391    ), SOMA_PAGMA  (P08591    ), 
SOMA_PANGG  (P69162    ), SOMA_PANPG  (P69161    ), SOMA_PANTR  (P58756    ), 
SOMA_PAROL  (P09537    ), SOMA_PERFV  (Q9DEV3    ), SOMA_PIG    (P01248    ), 
SOMA_PRIGL  (P34006    ), SOMA_PROAN  (O73848    ), SOMA_PSEDN  (P24363    ), 
SOMA_RABIT  (P46407    ), SOMA_RAT    (P01244    ), SOMA_RHIMB  (O73849    ), 
SOMA_SAIBB  (P58343    ), SOMA_SALSA  (P10814    ), SOMA_SCIOC  (Q9IB11    ), 
SOMA_SEBSC  (P87391    ), SOMA_SERQU  (P09539    ), SOMA_SHEEP  (P67930    ), 
SOMA_SIGGU  (Q9IBE5    ), SOMA_SOLSE  (P45643    ), SOMA_SPAAU  (P29971    ), 
SOMA_SPAEH  (O70615    ), SOMA_STRCA  (Q9PWG3    ), SOMA_TAKRU  (O12980    ), 
SOMA_THUAL  (P34747    ), SOMA_THUTH  (P09113    ), SOMA_TRITC  (Q98UF6    ), 
SOMA_TRIVU  (O62754    ), SOMA_VERVA  (O93566    ), SOMA_VICPA  (P37885    ), 
SOMA_VULVU  (P10766    ), SOML1_SPAAU (P54863    ), SOML2_SPAAU (P79894    ), 
SOML_ACITR  (O93262    ), SOML_ANGAN  (Q90216    ), SOML_CARAU  (P79697    ), 
SOML_CYCLU  (P45640    ), SOML_GADMO  (P21919    ), SOML_HIPHI  (P45641    ), 
SOML_ICTPU  (Q9I8J9    ), SOML_ONCKE  (P24405    ), SOML_ORYLA  (Q6E211    ), 
SOML_PAROL  (P20362    ), SOML_PROAN  (O73847    ), SOML_SCIOC  (Q9YGK7    ), 
SOML_SIGGU  (Q9PWG4    ), SOML_SOLSE  (P45642    ), SOML_TETMU  (Q9I9H4    )
» more

UniProtKB/Swiss-Prot
False negative sequences
22 sequences

PR2A1_MOUSE (Q9JHK0    ), PR2A1_RAT   (Q9JII3    ), PR2B1_MOUSE (Q9DAZ2    ), 
PR2B1_RAT   (Q9JKL9    ), PR3C1_MOUSE (Q9QUN5    ), PR3C1_RAT   (Q9QUL0    ), 
PR5A1_MOUSE (Q9JII2    ), PR5A1_RAT   (Q9JII4    ), PR6A1_MOUSE (O35257    ), 
PR6A1_RAT   (P24800    ), PR7B1_MOUSE (Q8CGZ9    ), PR7B1_RAT   (Q8CJ42    ), 
PR8A4_RAT   (P33580    ), PR8A6_MOUSE (Q9DAY2    ), PR8A7_RAT   (P33578    ), 
PR8A8_MOUSE (Q9DAS4    ), PR8A9_MOUSE (Q9CQ58    ), PR8A9_RAT   (Q920I0    ), 
PRL1_ALLMI  (P55751    ), PRL1_CRONO  (P55753    ), PRL2_ALLMI  (P55752    ), 
PRL2_CRONO  (P55754    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

GHR4_RAT    (P33581    )

		
UniProtKB/Swiss-Prot
False positive sequences
18 sequences

ALA2_ARATH  (P98205    ), CD3E_PIG    (Q7YRN2    ), ENV_FFV     (O56861    ), 
ENV_HV2EH   (Q89607    ), ENV_HV2UC   (Q76638    ), ENV_SFV1    (P23073    ), 
ENV_SFV3L   (P27399    ), GRT1A_DANRE (Q6PBU5    ), GRTP1_HUMAN (Q5TC63    ), 
GRTP1_MOUSE (Q9D3N8    ), GRTP1_RAT   (Q4QQU7    ), GRTP1_XENLA (Q6GLZ0    ), 
GRTP1_XENTR (Q6GL87    ), ODB2_CAEEL  (Q23571    ), PP341_ARATH (Q9SUH6    ), 
ZFHX4_CHICK (O73590    ), ZFHX4_HUMAN (Q86UP3    ), ZFHX4_MOUSE (Q9JJN2    )
» more

PDB
[Detailed view]
22 PDB

1A22; 1BP3; 1F6F; 1HGU; 1HUW; 1HWG; 1HWH; 1KF9; 1RW5; 1Z7C; 2Q98; 3D48; 3EW3; 3HHR; 3MZG; 3N06; 3N0P; 3NCB; 3NCC; 3NCE; 3NCF; 3NPZ
» more

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