Entry: PS00354

General information about the entry
Entry name HMGI_Y
Accession number PS00354
Entry type PATTERN
Date NOV-1990 (CREATED); OCT-1993 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00306
Name and characterization of the entry
DescriptionHMG-I and HMG-Y DNA-binding domain (A+T-hook).
Pattern [AT]-x(1,2)-[RK](2)-[GP]-R-G-R-P-[RK]-x.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 38 hits in 26 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 31 hits in 19 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 7 hits in 7 different sequences
  • Number of known missed hits: 6
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 81.58 %
  • Recall (true hits / (true hits + false negatives)): 83.78 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 3
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
AFF4_DROER  (B3NAM7), AFF4_DROGR  (B4JQ42), AFF4_DROME  (Q9VQI9), 
AFF4_DROMO  (B4KFE1), AFF4_DROPS  (Q29KG4), AFF4_DROVI  (B4LV24), 
AFF4_DROWI  (B4MUE1), AFF4_DROYA  (B4NXA8), HMGA1_CANFA (Q6URC2), 
HMGA1_CRIGR (Q9QXP3), HMGA1_HUMAN (P17096), HMGA1_MOUSE (P17095), 
HMGA1_RAT   (Q8K585), HMGA2_HUMAN (P52926), MLL3_HUMAN  (Q8NEZ4), 
MLL3_MOUSE  (Q8BRH4), MYNN_DANRE  (Q7ZVR6), PATZ1_HUMAN (Q9HBE1), 
PRH_PETCR   (P48786)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
AFF4_DROAN  (B3MLB7), CHIF_DROME  (Q9NK54), HMGA1_CHITE (Q23794), 
HMGA2_MOUSE (P52927), LI15B_CAEEL (Q27395), SFC3_SCHPO  (Q9UST7)
False positive hits (sequences which do not belong to the set under consideration):
BRLF1_SHV21 (Q01012), CE087_XENLA (Q5XG50), HQ1_COXBU   (Q45881), 
MLL1_HUMAN  (Q03164), MLL1_MOUSE  (P55200), SLX4_MAGO7  (A4R1T1), 
WHIB7_MYCS2 (A0QTT1)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 2EZD; 2EZE;

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