Entry: PS00354

General information about the entry

Entry name [info] HMGI_Y
Accession [info] PS00354
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED; 01-OCT-1993 DATA UPDATE; 05-JUL-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00306

Name and characterization of the entry

Description [info] HMG-I and HMG-Y DNA-binding domain (A+T-hook).
Pattern [info] 
[AT]-x(1,2)-[RK](2)-[GP]-R-G-R-P-[RK]-x.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_07 which contains 555'100 sequence entries.


Total number of hits 38 in 26 different sequences
Number of true positive hits 31 in 19 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 81.58 %
Recall (true positives / (true positives + false negatives)) 83.78 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 19 sequences 

AFF4_DROER  (B3NAM7    ), AFF4_DROGR  (B4JQ42    ), AFF4_DROME  (Q9VQI9    ), 

AFF4_DROMO  (B4KFE1    ), AFF4_DROPS  (Q29KG4    ), AFF4_DROVI  (B4LV24    ), 
AFF4_DROWI  (B4MUE1    ), AFF4_DROYA  (B4NXA8    ), HMGA1_CANLF (Q6URC2    ), 
HMGA1_CRIGR (Q9QXP3    ), HMGA1_HUMAN (P17096    ), HMGA1_MOUSE (P17095    ), 
HMGA1_RAT   (Q8K585    ), HMGA2_HUMAN (P52926    ), KMT2C_HUMAN (Q8NEZ4    ), 
KMT2C_MOUSE (Q8BRH4    ), MYNN_DANRE  (Q7ZVR6    ), PATZ1_HUMAN (Q9HBE1    ), 
PRH_PETCR   (P48786    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

AFF4_DROAN  (B3MLB7    ), CHIF_DROME  (Q9NK54    ), HMGA1_CHITE (Q23794    ), 

HMGA2_MOUSE (P52927    ), LI15B_CAEEL (Q27395    ), SFC3_SCHPO  (Q9UST7    )
» more

UniProtKB/Swiss-Prot
False positive sequences		 7 sequences 

BRLF1_SHV21 (Q01012    ), CE087_XENLA (Q5XG50    ), HQ1_COXBU   (Q45881    ), 

KMT2A_HUMAN (Q03164    ), KMT2A_MOUSE (P55200    ), SLX4_MAGO7  (A4R1T1    ), 
WHIB7_MYCS2 (A0QTT1    )
» more

PDB
[Detailed view]		 2 PDB

2EZD; 2EZE

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