Entry: PS00356

General information about the entry
Entry name HTH_LACI_1
Accession number PS00356
Entry type PATTERN
Date NOV-1990 (CREATED); NOV-1995 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00366
Name and characterization of the entry
DescriptionLacI-type HTH domain signature.
Pattern [LIVM]-x-[DE]-[LIVM]-A-x(2)-[STAGV]-x-V-[GSTP]-x(2)-[STAG]-[LIVMA]-x(2)- [LIVMFYAN]-[LIVMC].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 178 hits in 178 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 173 hits in 173 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 5 hits in 5 different sequences
  • Number of known missed hits: 8
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 3
  • Precision (true hits / (true hits + false positives)): 97.19 %
  • Recall (true hits / (true hits + false negatives)): 95.58 %
Comments
  • Taxonomic range: Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
ASCG_ECOLI  (P24242), CCPA_BACME  (P46828), CCPA_BACSU  (P25144), 
CCPA_STAAC  (Q5HF38), CCPA_STAAM  (P67655), CCPA_STAAN  (P99175), 
CCPA_STAAR  (Q6GFX2), CCPA_STAAS  (Q6G8J1), CCPA_STAAW  (Q8NW33), 
CCPA_STAEQ  (Q5HNH3), CCPA_STAES  (Q8CNV8), CCPA_STAXY  (Q56194), 
CCPA_STRMU  (O07329), CCPB_BACSU  (P37517), CRA_ECO57   (P0ACP3), 
CRA_ECOL6   (P0ACP2), CRA_ECOLI   (P0ACP1), CRA_SALTI   (P0A2P9), 
CRA_SALTY   (P0A2P8), CRA_SHIFL   (P0ACP4), CSCR_ECOLX  (P62604), 
CSCR_SHIFL  (P62572), CYTR_ECO57  (P0ACN9), CYTR_ECOL6  (P0ACN8), 
CYTR_ECOLI  (P0ACN7), CYTR_SHIFL  (P0ACP0), DEGA_BACSU  (P37947), 
EBGR_ECOLI  (P06846), ENDR_PAEPO  (P27871), EXUR_BACSU  (Q9JMQ1), 
GALR_ECOLI  (P03024), GALR_HAEIN  (P31766), GALR_LACCA  (O84905), 
GALR_SALTS  (E1WAQ4), GALR_SALTY  (P0CL11), GALR_STRTR  (Q9ZB11), 
GALS_ECOLI  (P25748), GALS_SALTY  (P41030), GLK_BURCA   (Q1BYA7), 
GLK_BURP1   (Q3JPP0), GLK_BURPS   (Q63RQ7), GLK_BURS3   (Q39IQ1), 
GLK_BURTA   (Q2SYA5), GLK_BURXL   (Q143F8), GNTR_ECOL6  (P0ACP6), 
GNTR_ECOLI  (P0ACP5), IDNR_ECOLI  (P39343), KDGR_BACSU  (P50844), 
LACI_ECOLI  (P03023), LACI_KLEPN  (P06220), MALI_ECOLI  (P18811), 
MALI_VIBFU  (P96158), MALR_CLOBU  (O05103), MALR_STAXY  (Q56201), 
MALR_STRCO  (P72396), MALR_STRPN  (P0A4T1), MALR_STRR6  (P0A4T2), 
MSMR_BACSU  (O34829), NFXB_PSEAE  (P32265), PEPR_LACDL  (Q48544), 
PURR_ACTP2  (A3N0H9), PURR_ACTP7  (B3H1F6), PURR_ACTPJ  (B0BP99), 
PURR_ACTSZ  (A6VNL0), PURR_ALISL  (B6EH86), PURR_CROS8  (A7MFD3), 
PURR_ECO24  (A7ZMC4), PURR_ECO27  (B7URZ9), PURR_ECO45  (B7MA12), 
PURR_ECO55  (B7L5L1), PURR_ECO57  (P0ACP8), PURR_ECO5E  (B5Z492), 
PURR_ECO7I  (B7NTX5), PURR_ECO81  (B7MVD4), PURR_ECO8A  (B7M0L5), 
PURR_ECOBW  (C4ZYC2), PURR_ECOHS  (A8A0K5), PURR_ECOK1  (A1ABJ9), 
PURR_ECOL5  (Q0THG9), PURR_ECOL6  (Q8FH72), PURR_ECOLC  (B1IQ96), 
PURR_ECOLI  (P0ACP7), PURR_ECOLU  (B7NBB1), PURR_ECOSE  (B6IB98), 
PURR_ECOSM  (B1LEM6), PURR_ECOUT  (Q1RBD7), PURR_EDWI9  (C5BE45), 
PURR_ERWCT  (Q6D5W3), PURR_ERWT9  (B2VEM5), PURR_ESCF3  (B7LQA9), 
PURR_HAEDU  (Q7VL44), PURR_HAEI8  (Q4QL70), PURR_HAEIE  (A5UCM9), 
PURR_HAEIG  (A5UIZ0), PURR_HAEIN  (P46456), PURR_HAEPS  (B8F4D0), 
PURR_HAES1  (Q0I4B4), PURR_HAES2  (B0UUN7), PURR_KLEP3  (B5XWL8), 
PURR_KLEP7  (A6TA06), PURR_MANSM  (Q65TP0), PURR_PASMU  (Q9CN88), 
PURR_PECCP  (C6DK36), PURR_PHOLL  (Q7N3V8), PURR_PHOPR  (Q6LQB9), 
PURR_PROMH  (B4EWM9), PURR_SALA4  (B5F6L7), PURR_SALAR  (A9MEJ1), 
PURR_SALCH  (Q57PK6), PURR_SALDC  (B5FIH3), PURR_SALEP  (B5QV29), 
PURR_SALG2  (B5RAM9), PURR_SALHS  (B4TH70), PURR_SALNS  (B4T567), 
PURR_SALPA  (Q5PH15), PURR_SALPB  (A9N0Y2), PURR_SALPC  (C0Q5V2), 
PURR_SALPK  (B5BKD9), PURR_SALSV  (B4TUY8), PURR_SALTI  (Q8Z6P1), 
PURR_SALTY  (O68446), PURR_SERP5  (A8GDV6), PURR_SHIB3  (B2U2G3), 
PURR_SHIBS  (Q321B7), PURR_SHIDS  (Q32FB3), PURR_SHIF8  (Q0T4B4), 
PURR_SHIFL  (P0ACP9), PURR_SHISS  (Q3Z213), PURR_VIBC3  (A5F7H0), 
PURR_VIBCH  (Q9KRC1), PURR_VIBCM  (C3LN44), PURR_VIBF1  (Q5E4H9), 
PURR_VIBFM  (B5FF00), PURR_VIBHB  (A7N1L2), PURR_VIBPA  (Q87QW9), 
PURR_VIBSL  (B7VMG4), PURR_VIBVU  (Q8DAQ5), PURR_VIBVY  (Q7MJ57), 
PURR_YERE8  (A1JP52), PURR_YERP3  (A7FHK2), PURR_YERPA  (Q1C774), 
PURR_YERPB  (B2K5I4), PURR_YERPE  (Q7CIS2), PURR_YERPG  (A9QZB3), 
PURR_YERPN  (Q1CIL0), PURR_YERPP  (A4TIQ4), PURR_YERPS  (Q66A32), 
PURR_YERPY  (B1JJ59), RBSR_BACHD  (Q9K6K2), RBSR_BACSU  (P36944), 
RBSR_ECO57  (P0ACQ2), RBSR_ECOL6  (P0ACQ1), RBSR_ECOLI  (P0ACQ0), 
RBSR_HAEIN  (P44329), RBSR_PASMU  (Q9CPA2), RBSR_SHIFL  (P0ACQ3), 
RBTR_ENTAE  (P07760), REG1_STRLI  (P72469), REGA_CLOAB  (P58258), 
REGA_CLOSA  (Q45831), SACR_LACLL  (Q04939), SCRR_KLEPN  (P37076), 
SCRR_PEDPE  (P43472), SCRR_SALTM  (P37077), SCRR_STAXY  (P74892), 
SCRR_STRMU  (Q54430), SCRR_VIBAL  (P24508), TRER_ECOLI  (P36673), 
TRER_SALTY  (P36674), YAML_STRLM  (P23823), YCJW_ECOLI  (P77615), 
YKVZ_BACSU  (O31690), YVDE_BACSU  (O06987)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
AGLR_RHIME  (Q9Z3R4), CELR_THEFU  (O87590), GANR_BACSU  (O07008), 
LACR_LACHE  (Q7WTB0), NTDR_BACSU  (O07567), RAFR_ECOLX  (P21867), 
RBSR_LACLA  (Q9CF41), Y4158_STRCO (Q05954)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
LACI_RHIRD  (Q01936), OPNR_AGRRH  (P27872), YAML_STRVL  (P23822)
False positive hits (sequences which do not belong to the set under consideration):
MDH_BACTN   (Q8A0W0), RPOB_GRAFK  (A0M3Y9), S29A3_BOVIN (A1A4N1), 
Y1018_STRA3 (P67251), Y983_STRA5  (P67252)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1BDH; 1BDI; 1CJG; 1EFA; 1JFS; 1JFT; 1JH9; 1JWL; 1L1M; 1LBG; 1LCC; 1LCD; 1LQC; 1OSL; 1PNR; 1PRU; 1PRV; 1QP0; 1QP4; 1QP7; 1QPZ; 1QQA; 1QQB; 1RZR; 1UXC; 1UXD; 1VPW; 1WET; 1Z04; 1ZAY; 1ZVV; 2BJC; 2HSG; 2JCG; 2KEI; 2KEJ; 2KEK; 2LCV; 2PE5; 2PUA; 2PUB; 2PUC; 2PUD; 2PUE; 2PUF; 2PUG; 3OQM; 3OQN; 3OQO;

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