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	Entry: PS00374

General information about the entry
Entry name	MGMT
Accession number	PS00374
Entry type	PATTERN
Date	NOV-1990 (CREATED); NOV-1990 (DATA UPDATE); APR-2013 (INFO UPDATE).
PROSITE Documentation	PDOC00320
Associated ProRule	PRU10017
Name and characterization of the entry
Description	Methylated-DNA--protein-cysteine methyltransferase active site.
Pattern	[LIVMF]-P-C-H-R-[LIVMF](2).
Numerical results
UniProtKB/Swiss-Prot release number: 2013_06, total number of sequence entries in that release: 540261. Total number of hits in UniProtKB/Swiss-Prot: 61 hits in 61 different sequences Number of hits on proteins that are known to belong to the set under consideration: 52 hits in 52 different sequences Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences Number of false hits (on unrelated proteins): 9 hits in 9 different sequences Number of known missed hits: 2 Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1 Precision (true hits / (true hits + false positives)): 85.25 % Recall (true hits / (true hits + false negatives)): 96.30 %
Comments
Taxonomic range: Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses Maximum known number of repetitions of the pattern in a single protein: 1 `Interesting' site in the pattern: 3,active_site VERSION: 1
Cross-references
UniProtKB/Swiss-Prot	True positive hits: ADAB_BACSU (P19220), ADA_ECOLI (P06134), ADA_SALTY (P26189), MGMT_CANAL (Q5A0Y8), MGMT_CANFA (Q6TDU1), MGMT_CANGA (Q6FNR0), MGMT_CRIGR (P26186), MGMT_HUMAN (P16455), MGMT_KLULA (Q6CPW2), MGMT_LODEL (A5E7M8), MGMT_MIMIV (Q5UNU9), MGMT_MOUSE (P26187), MGMT_PICST (A3LZM4), MGMT_RAT (P24528), MGMT_YEAS7 (A6ZXD3), MGMT_YEAST (P26188), OGT_ARCFU (O27970), OGT_BACSU (P11742), OGT_ECOLI (P0AFH0), OGT_HAEIN (P44687), OGT_METAC (Q8TI34), OGT_METBF (Q46EW4), OGT_METJA (Q58924), OGT_METMA (Q8PY44), OGT_METS5 (A4YH39), OGT_METTH (O26715), OGT_METVM (C9RE37), OGT_MYCBO (P0A697), OGT_MYCLE (P52982), OGT_MYCPA (Q9ZET8), OGT_MYCTU (P0A696), OGT_PYRAB (Q9V1N7), OGT_PYRAE (O93728), OGT_PYRFU (Q8TZV2), OGT_PYRHO (O59499), OGT_PYRKO (O74023), OGT_PYRSN (F4HK38), OGT_SALTI (P0A2U1), OGT_SALTY (P0A2U0), OGT_SHIFL (P0AFH1), OGT_SULAC (Q4J9C6), OGT_SULIA (C3N1B4), OGT_SULIK (C4KKV8), OGT_SULIL (C3MKT6), OGT_SULIM (C3MUC6), OGT_SULIN (C3NMY2), OGT_SULIY (C3N9B4), OGT_SULSO (Q97VW7), OGT_SULTO (Q973C7), OGT_THEBM (F0LIT8), OGT_THEGJ (C5A3L5), OGT_THESM (C6A382) False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): ATL1_SCHPO (Q9UTN9), OGT_METKA (Q8TZ11) `Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences): MGMT_BOVIN (P29177) False positive hits (sequences which do not belong to the set under consideration): CC108_HUMAN (Q6ZU64), KBTBC_HUMAN (Q3ZCT8), KBTBC_MOUSE (Q9D618), KLH40_HUMAN (Q2TBA0), KLH40_MOUSE (Q9D783), KLH40_XENLA (Q5U504), KLH40_XENTR (Q5EB39), KLH41_HUMAN (O60662), KLH41_RAT (Q9ER30) Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
PDB [Detailed view]	1EH6; 1MGT; 1QNT; 1SFE; 1T39; 1WRJ; 1YFH; 2G7H;

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