PROSITE logo

PROSITE entry PS00374


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] MGMT
Accession [info] PS00374
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-NOV-1990 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00320
Associated ProRule [info] PRU10017

Name and characterization of the entry

Description [info] Methylated-DNA--protein-cysteine methyltransferase active site.
Pattern [info] 
[LIVMF]-P-C-H-R-[LIVMF](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 67 in 67 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 14 in 14 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 79.10 %
Recall (true positives / (true positives + false negatives)) 96.36 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 53 sequences 

ADAB_BACSU  (P19220), ADA_ECOLI   (P06134), ADA_SALTY   (P26189), 

MGMT_CANAL  (Q5A0Y8), MGMT_CANGA  (Q6FNR0), MGMT_CANLF  (Q6TDU1), 
MGMT_CRIGR  (P26186), MGMT_HUMAN  (P16455), MGMT_KLULA  (Q6CPW2), 
MGMT_LODEL  (A5E7M8), MGMT_MIMIV  (Q5UNU9), MGMT_MOUSE  (P26187), 
MGMT_PICST  (A3LZM4), MGMT_RAT(P24528), MGMT_YEAS7  (A6ZXD3), 
MGMT_YEAST  (P26188), OGT_ARCFU   (O27970), OGT_BACSU   (P11742), 
OGT_ECOLI   (P0AFH0), OGT_HAEIN   (P44687), OGT_METAC   (Q8TI34), 
OGT_METBF   (Q46EW4), OGT_METJA   (Q58924), OGT_METMA   (Q8PY44), 
OGT_METS5   (A4YH39), OGT_METTH   (O26715), OGT_METVM   (C9RE37), 
OGT_MYCBO   (P0A697), OGT_MYCLE   (P52982), OGT_MYCPA   (Q9ZET8), 
OGT_MYCTO   (P9WJW4), OGT_MYCTU   (P9WJW5), OGT_PYRAB   (Q9V1N7), 
OGT_PYRAE   (O93728), OGT_PYRFU   (Q8TZV2), OGT_PYRHO   (O59499), 
OGT_PYRSN   (F4HK38), OGT_SACS2   (Q97VW7), OGT_SALTI   (P0A2U1), 
OGT_SALTY   (P0A2U0), OGT_SHIFL   (P0AFH1), OGT_SULAC   (Q4J9C6), 
OGT_SULIA   (C3N1B4), OGT_SULIK   (C4KKV8), OGT_SULIL   (C3MKT6), 
OGT_SULIM   (C3MUC6), OGT_SULIN   (C3NMY2), OGT_SULIY   (C3N9B4), 
OGT_SULTO   (Q973C7), OGT_THEBM   (F0LIT8), OGT_THEGJ   (C5A3L5), 
OGT_THEKO   (O74023), OGT_THESM   (C6A382)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

ATL1_SCHPO  (Q9UTN9), OGT_METKA   (Q8TZ11)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			1 sequence
			


			
MGMT_BOVIN  (P29177)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			14 sequences
			


			
CFA65_HUMAN (Q6ZU64), KBTBC_HUMAN (Q3ZCT8), KBTBC_MOUSE (Q9D618), 

			
KL40A_DANRE (B3DIV9), KL40B_DANRE (E9QJ30), KL41A_DANRE (E9QIN8), 
KL41B_DANRE (F1QEG2), KLH40_HUMAN (Q2TBA0), KLH40_MOUSE (Q9D783), 
KLH40_XENLA (Q5U504), KLH40_XENTR (Q5EB39), KLH41_HUMAN (O60662), 
KLH41_MOUSE (A2AUC9), KLH41_RAT   (Q9ER30)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			26 PDB
			


			1EH6; 1EH7; 1EH8; 1MGT; 1QNT; 1SFE; 1T39; 1WRJ; 1YFH; 2G7H; 4BHB; 4BHC; 
			
				4WX9; 4WXC; 4WXD; 4ZYE; 4ZYG; 6GA0; 7DKN; 7DQR; 7DQT; 8AES; 8RGG; 8RGH; 
				8RTY; 8RU2
			
			

			» more