Entry: PS00374

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General information about the entry

Entry name [info] MGMT
Accession [info] PS00374
Entry type [info] PATTERN
Date [info] NOV-1990 (CREATED); NOV-1990 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00320
Associated ProRule [info] PRU10017

Name and characterization of the entry

Description [info] Methylated-DNA--protein-cysteine methyltransferase active site.
Pattern [info]
[LIVMF]-P-C-H-R-[LIVMF](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 65 in 65 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits
Number of false positive hits 12 in 12 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 81.54 %
Recall (true positives / (true positives + false negatives)) 96.36 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

ADAB_BACSU  (P19220), ADA_ECOLI   (P06134), ADA_SALTY   (P26189), 
MGMT_CANAL  (Q5A0Y8), MGMT_CANFA  (Q6TDU1), MGMT_CANGA  (Q6FNR0), 
MGMT_CRIGR  (P26186), MGMT_HUMAN  (P16455), MGMT_KLULA  (Q6CPW2), 
MGMT_LODEL  (A5E7M8), MGMT_MIMIV  (Q5UNU9), MGMT_MOUSE  (P26187), 
MGMT_PICST  (A3LZM4), MGMT_RAT    (P24528), MGMT_YEAS7  (A6ZXD3), 
MGMT_YEAST  (P26188), OGT_ARCFU   (O27970), OGT_BACSU   (P11742), 
OGT_ECOLI   (P0AFH0), OGT_HAEIN   (P44687), OGT_METAC   (Q8TI34), 
OGT_METBF   (Q46EW4), OGT_METJA   (Q58924), OGT_METMA   (Q8PY44), 
OGT_METS5   (A4YH39), OGT_METTH   (O26715), OGT_METVM   (C9RE37), 
OGT_MYCBO   (P0A697), OGT_MYCLE   (P52982), OGT_MYCPA   (Q9ZET8), 
OGT_MYCTO   (P9WJW4), OGT_MYCTU   (P9WJW5), OGT_PYRAB   (Q9V1N7), 
OGT_PYRAE   (O93728), OGT_PYRFU   (Q8TZV2), OGT_PYRHO   (O59499), 
OGT_PYRSN   (F4HK38), OGT_SALTI   (P0A2U1), OGT_SALTY   (P0A2U0), 
OGT_SHIFL   (P0AFH1), OGT_SULAC   (Q4J9C6), OGT_SULIA   (C3N1B4), 
OGT_SULIK   (C4KKV8), OGT_SULIL   (C3MKT6), OGT_SULIM   (C3MUC6), 
OGT_SULIN   (C3NMY2), OGT_SULIY   (C3N9B4), OGT_SULSO   (Q97VW7), 
OGT_SULTO   (Q973C7), OGT_THEBM   (F0LIT8), OGT_THEGJ   (C5A3L5), 
OGT_THEKO   (O74023), OGT_THESM   (C6A382)
» More

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

ATL1_SCHPO  (Q9UTN9), OGT_METKA   (Q8TZ11)

		
UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

MGMT_BOVIN  (P29177)

		
UniProtKB/Swiss-Prot
False positive sequences
12 sequences

CC108_HUMAN (Q6ZU64), KBTBC_HUMAN (Q3ZCT8), KBTBC_MOUSE (Q9D618), 
KL40A_DANRE (B3DIV9), KL40B_DANRE (E9QJ30), KLH40_HUMAN (Q2TBA0), 
KLH40_MOUSE (Q9D783), KLH40_XENLA (Q5U504), KLH40_XENTR (Q5EB39), 
KLH41_HUMAN (O60662), KLH41_MOUSE (A2AUC9), KLH41_RAT   (Q9ER30)
» More

PDB
[Detailed view]
10 PDB

1EH6; 1MGT; 1QNT; 1SFE; 1T39; 1WRJ; 1YFH; 2G7H; 4BHB; 4BHC

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