Entry: PS00387

General information about the entry

Entry name [info] PPASE
Accession [info] PS00387
Entry type [info] PATTERN
Date [info] NOV-1990 (CREATED); NOV-1997 (DATA UPDATE); MAR-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00325

Name and characterization of the entry

Description [info] Inorganic pyrophosphatase signature.
Pattern [info]
D-[SGDN]-D-[PE]-[LIVMF]-D-[LIVMGAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_05 which contains 548'454 sequence entries.


Total number of hits 238 in 237 different sequences
Number of true positive hits 128 in 128 different sequences
Number of 'unknown' hits
Number of false positive hits 110 in 109 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 53.78 %
Recall (true positives / (true positives + false negatives)) 94.12 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] magnesium at position 1
Site [info] magnesium at position 3
Site [info] magnesium at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
128 sequences

IPYR1_ARATH (Q93V56), IPYR1_CHLRE (Q93Y52), IPYR1_PSESM (Q889M7), 
IPYR2_ARATH (P21216), IPYR2_CHLRE (Q949J1), IPYR2_HUMAN (Q9H2U2), 
IPYR2_MOUSE (Q91VM9), IPYR2_PSESM (Q87WD6), IPYR2_SCHPO (P87118), 
IPYR2_YEAST (P28239), IPYR3_ARATH (O82793), IPYR4_ARATH (Q9LFF9), 
IPYR5_ARATH (O82597), IPYR6_ARATH (Q9LXC9), IPYR_AERPE  (Q9YBA5), 
IPYR_AGRT5  (Q8UC37), IPYR_AQUAE  (O67501), IPYR_AQUPY  (Q8GQS5), 
IPYR_ASHGO  (Q757J8), IPYR_BACHD  (Q9KCG7), IPYR_BACP3  (P19514), 
IPYR_BARBK  (P51064), IPYR_BOVIN  (P37980), IPYR_BRUME  (P65744), 
IPYR_BRUSU  (P65745), IPYR_BUCAI  (P57190), IPYR_BUCAP  (Q8KA31), 
IPYR_BUCBP  (P59417), IPYR_CAEEL  (Q18680), IPYR_CAMJE  (Q9PHM9), 
IPYR_CANAL  (P83777), IPYR_CANGA  (Q6FRB7), IPYR_CHLCV  (Q821T4), 
IPYR_CHLMU  (Q9PLF1), IPYR_CHLT2  (B0B8Z8), IPYR_CHLTA  (Q3KKS0), 
IPYR_CHLTB  (B0BAM7), IPYR_CHLTR  (O84777), IPYR_COREF  (Q8FMF8), 
IPYR_CORGL  (Q8NM79), IPYR_DEBHA  (Q6BWA5), IPYR_DICDI  (Q54PV8), 
IPYR_DROME  (O77460), IPYR_ECO57  (P0A7B0), IPYR_ECOL6  (Q8FAG0), 
IPYR_ECOLI  (P0A7A9), IPYR_EMENI  (Q5B912), IPYR_ENCCU  (Q8SR69), 
IPYR_GEOSE  (O05724), IPYR_HAEDU  (Q7VPC0), IPYR_HAEIN  (P44529), 
IPYR_HALSA  (Q9HSF3), IPYR_HELPJ  (Q9ZLL5), IPYR_HELPY  (P56153), 
IPYR_HORVD  (O23979), IPYR_HUMAN  (Q15181), IPYR_KLULA  (P13998), 
IPYR_LEGPN  (O34955), IPYR_LEIXX  (Q6ACP7), IPYR_MACFA  (Q4R543), 
IPYR_MAIZE  (O48556), IPYR_METAC  (Q8TMI3), IPYR_METKA  (Q8TVE2), 
IPYR_METMA  (Q8PWY5), IPYR_METTH  (O26363), IPYR_MOUSE  (Q9D819), 
IPYR_MYCBO  (P65747), IPYR_MYCGE  (P47593), IPYR_MYCLE  (O69540), 
IPYR_MYCPE  (Q8EVW9), IPYR_MYCPN  (P75250), IPYR_MYCPU  (Q98Q96), 
IPYR_MYCTO  (P9WI54), IPYR_MYCTU  (P9WI55), IPYR_NANEQ  (Q74MY6), 
IPYR_NEIMA  (Q9JVG3), IPYR_NEIMB  (Q9K0G4), IPYR_NEUCR  (Q6MVH7), 
IPYR_NOSS1  (P80562), IPYR_ORYSI  (A2X8Q3), IPYR_ORYSJ  (Q0DYB1), 
IPYR_PASMU  (P57918), IPYR_PICPA  (O13505), IPYR_PICTO  (Q6KZB3), 
IPYR_PLAF7  (O77392), IPYR_PONAB  (Q5R8T6), IPYR_PSEAE  (Q9HWZ6), 
IPYR_PSEAO  (P58733), IPYR_PSEPK  (Q88QF6), IPYR_PYRAB  (Q9UY24), 
IPYR_PYRFU  (Q8U438), IPYR_PYRHO  (O59570), IPYR_RALSO  (Q8XWX1), 
IPYR_RHILO  (Q98ER2), IPYR_RHIME  (Q92LH1), IPYR_RHORT  (Q9RGQ1), 
IPYR_RICBR  (Q1RIN6), IPYR_RICCN  (Q92H74), IPYR_RICFE  (Q4UKW0), 
IPYR_RICPR  (Q9ZCW5), IPYR_RICTY  (Q68WE9), IPYR_SALTI  (P65749), 
IPYR_SALTY  (P65748), IPYR_SCHPO  (P19117), IPYR_SOLTU  (Q43187), 
IPYR_STRCO  (Q9X8I9), IPYR_SULAC  (P50308), IPYR_SULSO  (Q97W51), 
IPYR_SULTO  (Q974Y8), IPYR_SYNY3  (P80507), IPYR_THEAC  (P37981), 
IPYR_THEEB  (Q8DHR2), IPYR_THEKO  (Q5JIY3), IPYR_THELN  (P77992), 
IPYR_THET8  (P38576), IPYR_THEVO  (Q979E6), IPYR_UREPA  (Q9PQH6), 
IPYR_VIBCH  (Q9KP34), IPYR_VIBPA  (Q87SW1), IPYR_VIBVU  (Q8DE89), 
IPYR_VIBVY  (Q7MPD2), IPYR_WIGBR  (Q8D274), IPYR_XYLFA  (P65750), 
IPYR_XYLFT  (P65751), IPYR_YARLI  (Q6C1T4), IPYR_YEAST  (P00817), 
IPYR_YERPE  (Q8ZB98), IPYR_ZYGBA  (Q9C0T9)
» More

UniProtKB/Swiss-Prot
False negative sequences
8 sequences

IPYR_BRADU  (Q89WY0), IPYR_CAUCR  (Q9AC20), IPYR_CHLPN  (Q9Z6Y8), 
IPYR_GLUOX  (O05545), IPYR_LEPIC  (Q72MG4), IPYR_LEPIN  (Q8EZ21), 
IPYR_XANAC  (Q8PH18), IPYR_XANCP  (Q8P5M4)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

IPYR_BLAVI  (P82992), IPYR_CYAPA  (P80887), IPYR_DESVH  (P19371), 
IPYR_EUGGR  (P81987), IPYR_OCHDN  (P81988)
» More

UniProtKB/Swiss-Prot
False positive sequences
109 sequences

AER3_AERHY  (Q06305), AER4_AERHY  (Q06303), AER5_AERHY  (Q06306), 
AERA_AERHY  (P09167), AFTD_MYCS2  (A0QPD4), AGPA_RHIME  (Q9X4Y1), 
AROC_ACICJ  (A5FY49), AUBA_HALMA  (Q5V0I9), AUBA_NATPD  (Q3ITR7), 
BYE1_PICGU  (A5DDB7), C42_NPVOP   (P24653), CBAB_COMTE  (Q44257), 
CPL3_ARATH  (Q8LL04), CSM3_ASPFU  (A4DA84), CSM3_NEOFI  (A1D9E6), 
CSM3_NEUCR  (Q7SHE8), CYAD_DICDI  (Q55F68), DCN1_YARLI  (Q6C0B6), 
DIG1_CAEEL  (Q09165), DNAJ_BORBU  (P28616), DNAJ_BORGA  (Q661A4), 
DRE2_LACTC  (C5DJL0), END4_GEOSL  (Q74FS7), ENT5_YEAST  (Q03769), 
FAM21_MOUSE (Q6PGL7), FBD14_ARATH (Q9FNI9), FRMD3_HUMAN (A2A2Y4), 
FRMD3_PONAB (Q5R803), GDIR2_BOVIN (Q9TU03), GLK_BRUA1   (B2SC34), 
GLK_BRUA2   (Q2YJN9), GLK_BRUAB   (P0CB37), GLK_BRUME   (Q8YDC6), 
GLK_BRUSU   (Q8FV09), GLMM_SALAI  (A8M4B8), GLMM_SALTO  (A4XBI5), 
GSH1_VIBCH  (Q9KUG5), GYP7_DEBHA  (Q6BU76), HAP1_YEAS1  (B3RHD9), 
HAP1_YEAS2  (C7GQY3), HAP1_YEAS7  (A7A1D7), HAP1_YEAS8  (C8ZDL9), 
HAP1_YEASK  (G2WJ80), HAP1_YEAST  (P0CE41), HAP1_YEASX  (P0CS82), 
HETM_NOSS1  (P37693), JIP5_ASPFU  (Q4WNA1), KCMB3_HUMAN (Q9NPA1), 
MAK5_AJECN  (A6R9U4), MAP22_ASPTN (Q0CL94), MCA1_SCHPO  (O74477), 
MCL1A_DANRE (Q9PSI9), MNMA_NOCSJ  (A1SMB0), MTGA_PSEF5  (Q4K4C2), 
MYLKE_DICDI (Q54PB4), NAV1_HUMAN  (Q8NEY1), NAV1_MOUSE  (Q8CH77), 
NHAA1_RHOJR (Q0SG15), NPR3_DEBHA  (Q6BQU8), OBG_MYCGA   (Q7NB30), 
OTSA_MYCSK  (A1UM30), OTSA_MYCSS  (Q1B321), PA24A_HORSE (O77793), 
PA24A_HUMAN (P47712), PA24A_PONAB (Q5R8A5), PA24A_RABIT (Q9TT38), 
PA24A_RAT   (P50393), PPN1_NEUCR  (Q9P3S1), PRMA_ACIAD  (Q6F9P9), 
PSF2_PHANO  (Q0UTE1), PUX8_ARATH  (F4JPR7), RIMO_BACFN  (Q5LCF8), 
RIMO_BACFR  (Q64TK5), RPN8_YEAST  (Q08723), RPOB_ALKMQ  (A6TWJ0), 
RPOC_ANADE  (Q2II85), RPOC_ANADF  (A7HCH6), RPOC_ANASK  (B4UDT1), 
SUMO1_ARATH (P55852), SUMO1_ORYSJ (P55857), SUMO2_ARATH (Q9FLP6), 
SUMO4_ARATH (Q9FKC5), SUMO7_ARATH (Q3E8A8), T2EA_YEAST  (P36100), 
TREA_CANAX  (P52494), TUBE2_BPT7  (P03747), ULAC_ECO57  (P69821), 
ULAC_ECOL6  (Q8FAJ0), ULAC_ECOLI  (P69820), ULAC_SALCH  (Q57GJ7), 
ULAC_SALPA  (Q5PJ64), ULAC_SALTI  (Q8Z170), ULAC_SALTY  (Q8ZK88), 
ULAC_SHIBS  (Q31TC6), ULAC_SHIDS  (Q328K2), ULAC_SHIFL  (Q83P28), 
ULAC_SHISS  (Q3YUF3), UTP10_USTMA (Q4P937), XRN2_USTMA  (Q4P149), 
Y495_SALRD  (Q2S591), YCEI_ECO57  (P0A8X3), YCEI_ECOL6  (Q8CW58), 
YCEI_ECOLI  (P0A8X2), YCEI_SHIBS  (Q31ZB2), YCEI_SHIFL  (Q83LI9), 
YCEI_SHISS  (Q3Z360), YCF2_CHLSC  (A6MMG6), YP93_CAEEL  (Q09475), 
YTZ4_AGRVI  (P70796)
» More

PDB
[Detailed view]
44 PDB

1E6A; 1E9G; 1FAJ; 1HUJ; 1HUK; 1I40; 1I6T; 1IGP; 1INO; 1IPW; 1JFD; 1M38; 1MJW; 1MJZ; 1OBW; 1QEZ; 1SXV; 1UDE; 1WCF; 1WGI; 1WGJ; 1YGZ; 1YPP; 2AU6; 2AU7; 2AU8; 2AU9; 2AUU; 2BQX; 2BQY; 2EIP; 2IHP; 2IK0; 2IK1; 2IK9; 2PRD; 2UXS; 3D53; 3EMJ; 4ECP; 4LUG; 4UM4; 4XEL; 8PRK
» More

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