Entry: PS00387

General information about the entry

Entry name [info] PPASE
Accession [info] PS00387
Entry type [info] PATTERN
Date [info] NOV-1990 (CREATED); NOV-1997 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00325

Name and characterization of the entry

Description [info] Inorganic pyrophosphatase signature.
Pattern [info]
D-[SGDN]-D-[PE]-[LIVMF]-D-[LIVMGAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_08 which contains 551'987 sequence entries.


Total number of hits 239 in 238 different sequences
Number of true positive hits 128 in 128 different sequences
Number of 'unknown' hits 1
Number of false positive hits 110 in 109 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 53.78 %
Recall (true positives / (true positives + false negatives)) 94.12 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] magnesium at position 1
Site [info] magnesium at position 3
Site [info] magnesium at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
128 sequences

IPYR1_ARATH (Q93V56    ), IPYR1_CHLRE (Q93Y52    ), IPYR1_PSESM (Q889M7    ), 
IPYR2_ARATH (P21216    ), IPYR2_CHLRE (Q949J1    ), IPYR2_HUMAN (Q9H2U2    ), 
IPYR2_MOUSE (Q91VM9    ), IPYR2_PSESM (Q87WD6    ), IPYR2_SCHPO (P87118    ), 
IPYR2_YEAST (P28239    ), IPYR3_ARATH (O82793    ), IPYR4_ARATH (Q9LFF9    ), 
IPYR5_ARATH (O82597    ), IPYR6_ARATH (Q9LXC9    ), IPYR_AERPE  (Q9YBA5    ), 
IPYR_AGRFC  (Q8UC37    ), IPYR_AQUAE  (O67501    ), IPYR_AQUPY  (Q8GQS5    ), 
IPYR_ASHGO  (Q757J8    ), IPYR_BACHD  (Q9KCG7    ), IPYR_BACP3  (P19514    ), 
IPYR_BARBK  (P51064    ), IPYR_BOVIN  (P37980    ), IPYR_BRUME  (P65744    ), 
IPYR_BRUSU  (P65745    ), IPYR_BUCAI  (P57190    ), IPYR_BUCAP  (Q8KA31    ), 
IPYR_BUCBP  (P59417    ), IPYR_CAEEL  (Q18680    ), IPYR_CAMJE  (Q9PHM9    ), 
IPYR_CANAL  (P83777    ), IPYR_CANGA  (Q6FRB7    ), IPYR_CHLCV  (Q821T4    ), 
IPYR_CHLMU  (Q9PLF1    ), IPYR_CHLT2  (B0B8Z8    ), IPYR_CHLTA  (Q3KKS0    ), 
IPYR_CHLTB  (B0BAM7    ), IPYR_CHLTR  (O84777    ), IPYR_COREF  (Q8FMF8    ), 
IPYR_CORGL  (Q8NM79    ), IPYR_DEBHA  (Q6BWA5    ), IPYR_DICDI  (Q54PV8    ), 
IPYR_DROME  (O77460    ), IPYR_ECO57  (P0A7B0    ), IPYR_ECOL6  (Q8FAG0    ), 
IPYR_ECOLI  (P0A7A9    ), IPYR_EMENI  (Q5B912    ), IPYR_ENCCU  (Q8SR69    ), 
IPYR_GEOSE  (O05724    ), IPYR_HAEDU  (Q7VPC0    ), IPYR_HAEIN  (P44529    ), 
IPYR_HALSA  (Q9HSF3    ), IPYR_HELPJ  (Q9ZLL5    ), IPYR_HELPY  (P56153    ), 
IPYR_HORVD  (O23979    ), IPYR_HUMAN  (Q15181    ), IPYR_KLULA  (P13998    ), 
IPYR_LEGPN  (O34955    ), IPYR_LEIXX  (Q6ACP7    ), IPYR_MACFA  (Q4R543    ), 
IPYR_MAIZE  (O48556    ), IPYR_METAC  (Q8TMI3    ), IPYR_METKA  (Q8TVE2    ), 
IPYR_METMA  (Q8PWY5    ), IPYR_METTH  (O26363    ), IPYR_MOUSE  (Q9D819    ), 
IPYR_MYCBO  (P65747    ), IPYR_MYCGE  (P47593    ), IPYR_MYCLE  (O69540    ), 
IPYR_MYCPE  (Q8EVW9    ), IPYR_MYCPN  (P75250    ), IPYR_MYCPU  (Q98Q96    ), 
IPYR_MYCTO  (P9WI54    ), IPYR_MYCTU  (P9WI55    ), IPYR_NANEQ  (Q74MY6    ), 
IPYR_NEIMA  (Q9JVG3    ), IPYR_NEIMB  (Q9K0G4    ), IPYR_NEUCR  (Q6MVH7    ), 
IPYR_NOSS1  (P80562    ), IPYR_ORYSI  (A2X8Q3    ), IPYR_ORYSJ  (Q0DYB1    ), 
IPYR_PASMU  (P57918    ), IPYR_PICPA  (O13505    ), IPYR_PICTO  (Q6KZB3    ), 
IPYR_PLAF7  (O77392    ), IPYR_PONAB  (Q5R8T6    ), IPYR_PSEAE  (Q9HWZ6    ), 
IPYR_PSEAO  (P58733    ), IPYR_PSEPK  (Q88QF6    ), IPYR_PYRAB  (Q9UY24    ), 
IPYR_PYRFU  (Q8U438    ), IPYR_PYRHO  (O59570    ), IPYR_RALSO  (Q8XWX1    ), 
IPYR_RHILO  (Q98ER2    ), IPYR_RHIME  (Q92LH1    ), IPYR_RHORT  (Q9RGQ1    ), 
IPYR_RICBR  (Q1RIN6    ), IPYR_RICCN  (Q92H74    ), IPYR_RICFE  (Q4UKW0    ), 
IPYR_RICPR  (Q9ZCW5    ), IPYR_RICTY  (Q68WE9    ), IPYR_SALTI  (P65749    ), 
IPYR_SALTY  (P65748    ), IPYR_SCHPO  (P19117    ), IPYR_SOLTU  (Q43187    ), 
IPYR_STRCO  (Q9X8I9    ), IPYR_SULAC  (P50308    ), IPYR_SULSO  (Q97W51    ), 
IPYR_SULTO  (Q974Y8    ), IPYR_SYNY3  (P80507    ), IPYR_THEAC  (P37981    ), 
IPYR_THEEB  (Q8DHR2    ), IPYR_THEKO  (Q5JIY3    ), IPYR_THELN  (P77992    ), 
IPYR_THET8  (P38576    ), IPYR_THEVO  (Q979E6    ), IPYR_UREPA  (Q9PQH6    ), 
IPYR_VIBCH  (Q9KP34    ), IPYR_VIBPA  (Q87SW1    ), IPYR_VIBVU  (Q8DE89    ), 
IPYR_VIBVY  (Q7MPD2    ), IPYR_WIGBR  (Q8D274    ), IPYR_XYLFA  (P65750    ), 
IPYR_XYLFT  (P65751    ), IPYR_YARLI  (Q6C1T4    ), IPYR_YEAST  (P00817    ), 
IPYR_YERPE  (Q8ZB98    ), IPYR_ZYGBA  (Q9C0T9    )
» more

UniProtKB/Swiss-Prot
False negative sequences
8 sequences

IPYR_BRADU  (Q89WY0    ), IPYR_CAUCR  (Q9AC20    ), IPYR_CHLPN  (Q9Z6Y8    ), 
IPYR_GLUOX  (O05545    ), IPYR_LEPIC  (Q72MG4    ), IPYR_LEPIN  (Q8EZ21    ), 
IPYR_XANAC  (Q8PH18    ), IPYR_XANCP  (Q8P5M4    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

IPYR_BLAVI  (P82992    ), IPYR_CYAPA  (P80887    ), IPYR_DESVH  (P19371    ), 
IPYR_EUGGR  (P81987    ), IPYR_OCHDN  (P81988    )
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

JD1_AMOJI   (K7ZGS2    )

		
UniProtKB/Swiss-Prot
False positive sequences
109 sequences

AER3_AERHY  (Q06305    ), AER4_AERHY  (Q06303    ), AER5_AERHY  (Q06306    ), 
AERA_AERHY  (P09167    ), AFTD_MYCS2  (A0QPD4    ), AGPA_RHIME  (Q9X4Y1    ), 
AROC_ACICJ  (A5FY49    ), AUBA_HALMA  (Q5V0I9    ), AUBA_NATPD  (Q3ITR7    ), 
BYE1_PICGU  (A5DDB7    ), C42_NPVOP   (P24653    ), CBAB_COMTE  (Q44257    ), 
CPL3_ARATH  (Q8LL04    ), CSM3_ASPFU  (A4DA84    ), CSM3_NEOFI  (A1D9E6    ), 
CSM3_NEUCR  (Q7SHE8    ), CYAD_DICDI  (Q55F68    ), DCN1_YARLI  (Q6C0B6    ), 
DIG1_CAEEL  (Q09165    ), DNAJ_BORBP  (Q661A4    ), DNAJ_BORBU  (P28616    ), 
DRE2_LACTC  (C5DJL0    ), END4_GEOSL  (Q74FS7    ), ENT5_YEAST  (Q03769    ), 
FAM21_MOUSE (Q6PGL7    ), FBD14_ARATH (Q9FNI9    ), FRMD3_HUMAN (A2A2Y4    ), 
FRMD3_PONAB (Q5R803    ), GDIR2_BOVIN (Q9TU03    ), GLK_BRUA1   (B2SC34    ), 
GLK_BRUA2   (Q2YJN9    ), GLK_BRUAB   (P0CB37    ), GLK_BRUME   (Q8YDC6    ), 
GLK_BRUSU   (Q8FV09    ), GLMM_SALAI  (A8M4B8    ), GLMM_SALTO  (A4XBI5    ), 
GSH1_VIBCH  (Q9KUG5    ), GYP7_DEBHA  (Q6BU76    ), HAP1_YEAS1  (B3RHD9    ), 
HAP1_YEAS2  (C7GQY3    ), HAP1_YEAS7  (A7A1D7    ), HAP1_YEAS8  (C8ZDL9    ), 
HAP1_YEASK  (G2WJ80    ), HAP1_YEAST  (P0CE41    ), HAP1_YEASX  (P0CS82    ), 
HETM_NOSS1  (P37693    ), JIP5_ASPFU  (Q4WNA1    ), KCMB3_HUMAN (Q9NPA1    ), 
MAK5_AJECN  (A6R9U4    ), MAP22_ASPTN (Q0CL94    ), MCA1_SCHPO  (O74477    ), 
MCL1A_DANRE (Q9PSI9    ), MNMA_NOCSJ  (A1SMB0    ), MTGA_PSEF5  (Q4K4C2    ), 
MYLKE_DICDI (Q54PB4    ), NAV1_HUMAN  (Q8NEY1    ), NAV1_MOUSE  (Q8CH77    ), 
NHAA1_RHOJR (Q0SG15    ), NPR3_DEBHA  (Q6BQU8    ), OBG_MYCGA   (Q7NB30    ), 
OTSA_MYCSK  (A1UM30    ), OTSA_MYCSS  (Q1B321    ), PA24A_HORSE (O77793    ), 
PA24A_HUMAN (P47712    ), PA24A_PONAB (Q5R8A5    ), PA24A_RABIT (Q9TT38    ), 
PA24A_RAT   (P50393    ), PPN1_NEUCR  (Q9P3S1    ), PRMA_ACIAD  (Q6F9P9    ), 
PSF2_PHANO  (Q0UTE1    ), PUX8_ARATH  (F4JPR7    ), RIMO_BACFN  (Q5LCF8    ), 
RIMO_BACFR  (Q64TK5    ), RPN8_YEAST  (Q08723    ), RPOB_ALKMQ  (A6TWJ0    ), 
RPOC_ANADE  (Q2II85    ), RPOC_ANADF  (A7HCH6    ), RPOC_ANASK  (B4UDT1    ), 
SUMO1_ARATH (P55852    ), SUMO1_ORYSJ (P55857    ), SUMO2_ARATH (Q9FLP6    ), 
SUMO4_ARATH (Q9FKC5    ), SUMO7_ARATH (Q3E8A8    ), T2EA_YEAST  (P36100    ), 
TREA_CANAX  (P52494    ), TUBE2_BPT7  (P03747    ), ULAC_ECO57  (P69821    ), 
ULAC_ECOL6  (Q8FAJ0    ), ULAC_ECOLI  (P69820    ), ULAC_SALCH  (Q57GJ7    ), 
ULAC_SALPA  (Q5PJ64    ), ULAC_SALTI  (Q8Z170    ), ULAC_SALTY  (Q8ZK88    ), 
ULAC_SHIBS  (Q31TC6    ), ULAC_SHIDS  (Q328K2    ), ULAC_SHIFL  (Q83P28    ), 
ULAC_SHISS  (Q3YUF3    ), UTP10_USTMA (Q4P937    ), XRN2_USTMA  (Q4P149    ), 
Y495_SALRD  (Q2S591    ), YCEI_ECO57  (P0A8X3    ), YCEI_ECOL6  (Q8CW58    ), 
YCEI_ECOLI  (P0A8X2    ), YCEI_SHIBS  (Q31ZB2    ), YCEI_SHIFL  (Q83LI9    ), 
YCEI_SHISS  (Q3Z360    ), YCF2_CHLSC  (A6MMG6    ), YP93_CAEEL  (Q09475    ), 
YTZ4_AGRVI  (P70796    )
» more

PDB
[Detailed view]
49 PDB

1E6A; 1E9G; 1FAJ; 1HUJ; 1HUK; 1I40; 1I6T; 1IGP; 1INO; 1IPW; 1JFD; 1M38; 1MJW; 1MJZ; 1OBW; 1QEZ; 1SXV; 1UDE; 1WCF; 1WGI; 1WGJ; 1YGZ; 1YPP; 2AU6; 2AU7; 2AU8; 2AU9; 2AUU; 2BQX; 2BQY; 2EIP; 2IHP; 2IK0; 2IK1; 2IK9; 2PRD; 2UXS; 3D53; 3EMJ; 4ECP; 4LUG; 4UM4; 4XEL; 4Z70; 4Z71; 4Z72; 4Z73; 4Z74; 8PRK
» more

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