To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS00387

General information about the entry

Entry name [info] PPASE
Accession [info] PS00387
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED; 01-NOV-1997 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00325

Name and characterization of the entry

Description [info] Inorganic pyrophosphatase signature.
Pattern [info]
D-[SGDN]-D-[PE]-[LIVMF]-D-[LIVMGAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 239 in 238 different sequences
Number of true positive hits 128 in 128 different sequences
Number of 'unknown' hits 1
Number of false positive hits 110 in 109 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 53.78 %
Recall (true positives / (true positives + false negatives)) 94.12 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] magnesium at position 1
Site [info] magnesium at position 3
Site [info] magnesium at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
128 sequences

IPYR1_ARATH (Q93V56    ), IPYR1_CHLRE (Q93Y52    ), IPYR1_PSESM (Q889M7    ), 
IPYR2_ARATH (P21216    ), IPYR2_CHLRE (Q949J1    ), IPYR2_HUMAN (Q9H2U2    ), 
IPYR2_MOUSE (Q91VM9    ), IPYR2_PSESM (Q87WD6    ), IPYR2_SCHPO (P87118    ), 
IPYR2_YEAST (P28239    ), IPYR3_ARATH (O82793    ), IPYR4_ARATH (Q9LFF9    ), 
IPYR5_ARATH (O82597    ), IPYR6_ARATH (Q9LXC9    ), IPYR_AERPE  (Q9YBA5    ), 
IPYR_AGRFC  (Q8UC37    ), IPYR_AQUAE  (O67501    ), IPYR_AQUPY  (Q8GQS5    ), 
IPYR_ASHGO  (Q757J8    ), IPYR_BACHD  (Q9KCG7    ), IPYR_BACP3  (P19514    ), 
IPYR_BARBK  (P51064    ), IPYR_BOVIN  (P37980    ), IPYR_BRUME  (P65744    ), 
IPYR_BRUSU  (P65745    ), IPYR_BUCAI  (P57190    ), IPYR_BUCAP  (Q8KA31    ), 
IPYR_BUCBP  (P59417    ), IPYR_CAEEL  (Q18680    ), IPYR_CAMJE  (Q9PHM9    ), 
IPYR_CANAL  (P83777    ), IPYR_CANGA  (Q6FRB7    ), IPYR_CHLCV  (Q821T4    ), 
IPYR_CHLMU  (Q9PLF1    ), IPYR_CHLT2  (B0B8Z8    ), IPYR_CHLTA  (Q3KKS0    ), 
IPYR_CHLTB  (B0BAM7    ), IPYR_CHLTR  (O84777    ), IPYR_COREF  (Q8FMF8    ), 
IPYR_CORGL  (Q8NM79    ), IPYR_DEBHA  (Q6BWA5    ), IPYR_DICDI  (Q54PV8    ), 
IPYR_DROME  (O77460    ), IPYR_ECO57  (P0A7B0    ), IPYR_ECOL6  (Q8FAG0    ), 
IPYR_ECOLI  (P0A7A9    ), IPYR_EMENI  (Q5B912    ), IPYR_ENCCU  (Q8SR69    ), 
IPYR_GEOSE  (O05724    ), IPYR_HAEDU  (Q7VPC0    ), IPYR_HAEIN  (P44529    ), 
IPYR_HALSA  (Q9HSF3    ), IPYR_HELPJ  (Q9ZLL5    ), IPYR_HELPY  (P56153    ), 
IPYR_HORVV  (O23979    ), IPYR_HUMAN  (Q15181    ), IPYR_KLULA  (P13998    ), 
IPYR_LEGPN  (O34955    ), IPYR_LEIXX  (Q6ACP7    ), IPYR_MACFA  (Q4R543    ), 
IPYR_MAIZE  (O48556    ), IPYR_METAC  (Q8TMI3    ), IPYR_METKA  (Q8TVE2    ), 
IPYR_METMA  (Q8PWY5    ), IPYR_METTH  (O26363    ), IPYR_MOUSE  (Q9D819    ), 
IPYR_MYCBO  (P65747    ), IPYR_MYCGE  (P47593    ), IPYR_MYCLE  (O69540    ), 
IPYR_MYCPE  (Q8EVW9    ), IPYR_MYCPN  (P75250    ), IPYR_MYCPU  (Q98Q96    ), 
IPYR_MYCTO  (P9WI54    ), IPYR_MYCTU  (P9WI55    ), IPYR_NANEQ  (Q74MY6    ), 
IPYR_NEIMA  (Q9JVG3    ), IPYR_NEIMB  (Q9K0G4    ), IPYR_NEUCR  (Q6MVH7    ), 
IPYR_NOSS1  (P80562    ), IPYR_ORYSI  (A2X8Q3    ), IPYR_ORYSJ  (Q0DYB1    ), 
IPYR_PASMU  (P57918    ), IPYR_PICPA  (O13505    ), IPYR_PICTO  (Q6KZB3    ), 
IPYR_PLAF7  (O77392    ), IPYR_PONAB  (Q5R8T6    ), IPYR_PSEAE  (Q9HWZ6    ), 
IPYR_PSEAO  (P58733    ), IPYR_PSEPK  (Q88QF6    ), IPYR_PYRAB  (Q9UY24    ), 
IPYR_PYRFU  (Q8U438    ), IPYR_PYRHO  (O59570    ), IPYR_RALSO  (Q8XWX1    ), 
IPYR_RHILO  (Q98ER2    ), IPYR_RHIME  (Q92LH1    ), IPYR_RHORT  (Q9RGQ1    ), 
IPYR_RICBR  (Q1RIN6    ), IPYR_RICCN  (Q92H74    ), IPYR_RICFE  (Q4UKW0    ), 
IPYR_RICPR  (Q9ZCW5    ), IPYR_RICTY  (Q68WE9    ), IPYR_SALTI  (P65749    ), 
IPYR_SALTY  (P65748    ), IPYR_SCHPO  (P19117    ), IPYR_SOLTU  (Q43187    ), 
IPYR_STRCO  (Q9X8I9    ), IPYR_SULAC  (P50308    ), IPYR_SULSO  (Q97W51    ), 
IPYR_SULTO  (Q974Y8    ), IPYR_SYNY3  (P80507    ), IPYR_THEAC  (P37981    ), 
IPYR_THEEB  (Q8DHR2    ), IPYR_THEKO  (Q5JIY3    ), IPYR_THELN  (P77992    ), 
IPYR_THET8  (P38576    ), IPYR_THEVO  (Q979E6    ), IPYR_UREPA  (Q9PQH6    ), 
IPYR_VIBCH  (Q9KP34    ), IPYR_VIBPA  (Q87SW1    ), IPYR_VIBVU  (Q8DE89    ), 
IPYR_VIBVY  (Q7MPD2    ), IPYR_WIGBR  (Q8D274    ), IPYR_XYLFA  (P65750    ), 
IPYR_XYLFT  (P65751    ), IPYR_YARLI  (Q6C1T4    ), IPYR_YEAST  (P00817    ), 
IPYR_YERPE  (Q8ZB98    ), IPYR_ZYGBA  (Q9C0T9    )
» more

UniProtKB/Swiss-Prot
False negative sequences
8 sequences

IPYR_BRADU  (Q89WY0    ), IPYR_CAUCR  (Q9AC20    ), IPYR_CHLPN  (Q9Z6Y8    ), 
IPYR_GLUOX  (O05545    ), IPYR_LEPIC  (Q72MG4    ), IPYR_LEPIN  (Q8EZ21    ), 
IPYR_XANAC  (Q8PH18    ), IPYR_XANCP  (Q8P5M4    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

IPYR_BLAVI  (P82992    ), IPYR_CYAPA  (P80887    ), IPYR_DESVH  (P19371    ), 
IPYR_EUGGR  (P81987    ), IPYR_OCHDN  (P81988    )
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

JD1_AMOJI   (K7ZGS2    )

		
UniProtKB/Swiss-Prot
False positive sequences
109 sequences

AER3_AERHY  (Q06305    ), AER4_AERHY  (Q06303    ), AER5_AERHY  (Q06306    ), 
AERA_AERHY  (P09167    ), AFTD_MYCS2  (A0QPD4    ), AGPA_RHIME  (Q9X4Y1    ), 
AROC_ACICJ  (A5FY49    ), AUBA_HALMA  (Q5V0I9    ), AUBA_NATPD  (Q3ITR7    ), 
BYE1_PICGU  (A5DDB7    ), C42_NPVOP   (P24653    ), CBAB_COMTE  (Q44257    ), 
CPL3_ARATH  (Q8LL04    ), CSM3_ASPFU  (A4DA84    ), CSM3_NEOFI  (A1D9E6    ), 
CSM3_NEUCR  (Q7SHE8    ), CYAD_DICDI  (Q55F68    ), DCN1_YARLI  (Q6C0B6    ), 
DIG1_CAEEL  (Q09165    ), DNAJ_BORBP  (Q661A4    ), DNAJ_BORBU  (P28616    ), 
DRE2_LACTC  (C5DJL0    ), END4_GEOSL  (Q74FS7    ), ENT5_YEAST  (Q03769    ), 
FBD14_ARATH (Q9FNI9    ), FRMD3_HUMAN (A2A2Y4    ), FRMD3_PONAB (Q5R803    ), 
GDIR2_BOVIN (Q9TU03    ), GLK_BRUA1   (B2SC34    ), GLK_BRUA2   (Q2YJN9    ), 
GLK_BRUAB   (P0CB37    ), GLK_BRUME   (Q8YDC6    ), GLK_BRUSU   (Q8FV09    ), 
GLMM_SALAI  (A8M4B8    ), GLMM_SALTO  (A4XBI5    ), GSH1_VIBCH  (Q9KUG5    ), 
GYP7_DEBHA  (Q6BU76    ), HAP1_YEAS1  (B3RHD9    ), HAP1_YEAS2  (C7GQY3    ), 
HAP1_YEAS7  (A7A1D7    ), HAP1_YEAS8  (C8ZDL9    ), HAP1_YEASK  (G2WJ80    ), 
HAP1_YEAST  (P0CE41    ), HAP1_YEASX  (P0CS82    ), HETM_NOSS1  (P37693    ), 
JIP5_ASPFU  (Q4WNA1    ), KCMB3_HUMAN (Q9NPA1    ), MAK5_AJECN  (A6R9U4    ), 
MAP22_ASPTN (Q0CL94    ), MCA1_SCHPO  (O74477    ), MCL1A_DANRE (Q9PSI9    ), 
MNMA_NOCSJ  (A1SMB0    ), MTGA_PSEF5  (Q4K4C2    ), MYLKE_DICDI (Q54PB4    ), 
NAV1_HUMAN  (Q8NEY1    ), NAV1_MOUSE  (Q8CH77    ), NHAA1_RHOJR (Q0SG15    ), 
NPR3_DEBHA  (Q6BQU8    ), OBG_MYCGA   (Q7NB30    ), OTSA_MYCSK  (A1UM30    ), 
OTSA_MYCSS  (Q1B321    ), PA24A_HORSE (O77793    ), PA24A_HUMAN (P47712    ), 
PA24A_PONAB (Q5R8A5    ), PA24A_RABIT (Q9TT38    ), PA24A_RAT   (P50393    ), 
PPN1_NEUCR  (Q9P3S1    ), PRMA_ACIAD  (Q6F9P9    ), PSF2_PHANO  (Q0UTE1    ), 
PUX8_ARATH  (F4JPR7    ), RIMO_BACFN  (Q5LCF8    ), RIMO_BACFR  (Q64TK5    ), 
RPN8_YEAST  (Q08723    ), RPOB_ALKMQ  (A6TWJ0    ), RPOC_ANADE  (Q2II85    ), 
RPOC_ANADF  (A7HCH6    ), RPOC_ANASK  (B4UDT1    ), SUMO1_ARATH (P55852    ), 
SUMO1_ORYSJ (P55857    ), SUMO2_ARATH (Q9FLP6    ), SUMO4_ARATH (Q9FKC5    ), 
SUMO7_ARATH (Q3E8A8    ), T2EA_YEAST  (P36100    ), TREA_CANAX  (P52494    ), 
TUBE2_BPT7  (P03747    ), ULAC_ECO57  (P69821    ), ULAC_ECOL6  (Q8FAJ0    ), 
ULAC_ECOLI  (P69820    ), ULAC_SALCH  (Q57GJ7    ), ULAC_SALPA  (Q5PJ64    ), 
ULAC_SALTI  (Q8Z170    ), ULAC_SALTY  (Q8ZK88    ), ULAC_SHIBS  (Q31TC6    ), 
ULAC_SHIDS  (Q328K2    ), ULAC_SHIFL  (Q83P28    ), ULAC_SHISS  (Q3YUF3    ), 
UTP10_USTMA (Q4P937    ), WASC2_MOUSE (Q6PGL7    ), XRN2_USTMA  (Q4P149    ), 
Y495_SALRD  (Q2S591    ), YCEI_ECO57  (P0A8X3    ), YCEI_ECOL6  (Q8CW58    ), 
YCEI_ECOLI  (P0A8X2    ), YCEI_SHIBS  (Q31ZB2    ), YCEI_SHIFL  (Q83LI9    ), 
YCEI_SHISS  (Q3Z360    ), YCF2_CHLSC  (A6MMG6    ), YP93_CAEEL  (Q09475    ), 
YTZ4_AGRVI  (P70796    )
» more

PDB
[Detailed view]
52 PDB

1E6A; 1E9G; 1FAJ; 1HUJ; 1HUK; 1I40; 1I6T; 1IGP; 1INO; 1IPW; 1JFD; 1M38; 1MJW; 1MJZ; 1OBW; 1QEZ; 1SXV; 1UDE; 1WCF; 1WGI; 1WGJ; 1YGZ; 1YPP; 2AU6; 2AU7; 2AU8; 2AU9; 2AUU; 2BQX; 2BQY; 2EIP; 2IHP; 2IK0; 2IK1; 2IK9; 2PRD; 2UXS; 3D53; 3EMJ; 4ECP; 4LUG; 4UM4; 4XEL; 4Z70; 4Z71; 4Z72; 4Z73; 4Z74; 5KDE; 5KDF; 5TEA; 8PRK
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission