Entry: PS00408

General information about the entry
Entry name CONNEXINS_2
Accession number PS00408
Entry type PATTERN
Date NOV-1990 (CREATED); APR-2006 (DATA UPDATE); APR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00341
Name and characterization of the entry
DescriptionConnexins signature 2.
Pattern C-x(3,4)-P-C-x(2,3)-[LIVMTA]-[DENT]-C-[FYN]-[LIVMQ]-[SA]-[KRH]-P.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_06, total number of sequence entries in that release: 540261.
  • Total number of hits in UniProtKB/Swiss-Prot: 107 hits in 107 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 107 hits in 107 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 2
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 98.17 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 1,disulfide
  • `Interesting' site in the pattern: 4,disulfide
  • `Interesting' site in the pattern: 8,disulfide
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
CX32_DANRE  (Q7T047), CX32_MICUN  (P51915), CX33_MICUN  (P51916), 
CXA10_HUMAN (Q969M2), CXA10_MOUSE (Q9WUS4), CXA1_BOVIN  (P18246), 
CXA1_CANFA  (Q6S9C0), CXA1_CHICK  (P14154), CXA1_CHLAE  (Q6TYA9), 
CXA1_DANRE  (O57474), CXA1_ERIEU  (Q6TYA8), CXA1_HUMAN  (P17302), 
CXA1_MACFA  (Q4R4S7), CXA1_MOUSE  (P23242), CXA1_PIG    (Q29101), 
CXA1_RABIT  (Q6TYA7), CXA1_RAT    (P08050), CXA1_URSAM  (A6XKM2), 
CXA1_XENLA  (P16863), CXA2_XENLA  (P16864), CXA3_BOVIN  (P41987), 
CXA3_CHICK  (P29415), CXA3_HUMAN  (Q9Y6H8), CXA3_MOUSE  (Q64448), 
CXA3_RAT    (P29414), CXA3_SHEEP  (Q9TU17), CXA4_BOVIN  (A4IFL1), 
CXA4_HUMAN  (P35212), CXA4_MOUSE  (P28235), CXA4_RAT    (Q03190), 
CXA4_XENLA  (P51914), CXA4_XENTR  (Q0V990), CXA5_BOVIN  (Q0VCR2), 
CXA5_CANFA  (P33725), CXA5_CHICK  (P18860), CXA5_HUMAN  (P36382), 
CXA5_MOUSE  (Q01231), CXA5_RAT    (P28234), CXA6_MOUSE  (Q6S5G4), 
CXA6_RAT    (P28233), CXA8_CHICK  (P36381), CXA8_HUMAN  (P48165), 
CXA8_MOUSE  (P28236), CXA8_RAT    (Q8K4Q9), CXA8_SHEEP  (P55917), 
CXA9_HUMAN  (P57773), CXB1_BOVIN  (O18968), CXB1_HORSE  (Q6WGK6), 
CXB1_HUMAN  (P08034), CXB1_MACFA  (Q60HF7), CXB1_MOUSE  (P28230), 
CXB1_RAT    (P08033), CXB1_XENLA  (P08983), CXB2_BOVIN  (A2VE67), 
CXB2_GORGO  (Q8MHW5), CXB2_HUMAN  (P29033), CXB2_HYLLA  (Q7JGL3), 
CXB2_MACMU  (Q8MIT8), CXB2_MOUSE  (Q00977), CXB2_PONPY  (Q8MIT9), 
CXB2_RAT    (P21994), CXB2_SHEEP  (P46691), CXB3_BOVIN  (Q58D78), 
CXB3_HUMAN  (O75712), CXB3_MOUSE  (P28231), CXB3_RAT    (P25305), 
CXB4_HUMAN  (Q9NTQ9), CXB4_MOUSE  (Q02738), CXB4_RAT    (P36380), 
CXB5_HUMAN  (O95377), CXB5_MOUSE  (Q02739), CXB5_RAT    (P28232), 
CXB6_BOVIN  (Q5E9Z5), CXB6_CHICK  (O93533), CXB6_HUMAN  (O95452), 
CXB6_MOUSE  (P70689), CXB7_HUMAN  (Q6PEY0), CXD2_BOVIN  (Q866T7), 
CXD2_HUMAN  (Q9UKL4), CXD2_LEUER  (P69998), CXD2_MOUSE  (O54851), 
CXD2_RAJOC  (P69999), CXD2_RAT    (O70610), CXD3_HUMAN  (Q8N144), 
CXD3_MOUSE  (Q91YD1), CXD4_HUMAN  (Q96KN9), CXD4_MACFA  (Q9N0B3), 
CXD4_MOUSE  (Q8BSD4), CXG1_BOVIN  (Q2HJ66), CXG1_CANFA  (P28228), 
CXG1_CHICK  (P18861), CXG1_CRIGR  (Q6R4A8), CXG1_DANRE  (Q92052), 
CXG1_HUMAN  (P36383), CXG1_MESAU  (Q6PYT3), CXG1_MOUSE  (P28229), 
CXG1_PIG    (A4GVD1), CXG1_RAT    (A4GG66), CXG1_XENLA  (Q7ZXS7), 
CXG1_XENTR  (Q6NZH5), CXG2_BOVIN  (Q29RK8), CXG2_HUMAN  (Q5T442), 
CXG2_MOUSE  (Q8BQU6), CXG2_RAT    (Q80XF7), CXG3_BOVIN  (A3KN25), 
CXG3_HUMAN  (Q8NFK1), CXG3_MOUSE  (Q921C1)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
CXE1_HUMAN  (A6NN92), CXE1_MOUSE  (Q9CX92)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
CXA4_PIG    (Q29559)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1XIR; 2ZW3; 3IZ1; 3IZ2;

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