Entry: PS00471

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General information about the entry

Entry name [info] SMALL_CYTOKINES_CXC
Accession [info] PS00471
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); APR-2006 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00434

Name and characterization of the entry

Description [info] Small cytokines (intercrine/chemokine) C-x-C subfamily signature.
Pattern [info]
C-x-C-[LIVMS]-x(4,6)-[LIVMFY]-x(2)-[RKSEQNA]-x-[LIVM]-x(2)-[LIVMA]-x(5)-
[STAG]-x(2)-C-x(3)-[EQ]-[LIVM](2)-x(9,10)-C-[LV]-[DN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 64 in 64 different sequences
Number of true positive hits 64 in 64 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 15
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 81.01 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 16
Site [info] disulfide at position 21
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

AMC2_PIG    (P22952), AMC_RABIT   (P82535), CXCL2_HUMAN (P19875), 
CXCL2_MOUSE (P10889), CXCL2_RAT   (P30348), CXCL3_HUMAN (P19876), 
CXCL3_MOUSE (Q6W5C0), CXCL3_RAT   (Q10746), CXCL5_HUMAN (P42830), 
CXCL5_MOUSE (P50228), CXCL5_RAT   (P97885), CXCL6_BOVIN (P80221), 
CXCL6_HORSE (Q8MIN2), CXCL6_HUMAN (P80162), CXCL7_HUMAN (P02775), 
CXCL7_PIG   (P43030), CXCL9_BOVIN (A9QWP9), CXCL9_HUMAN (Q07325), 
CXCL9_MOUSE (P18340), CXL10_BOVIN (Q2KIQ8), CXL10_CANFA (Q5KSV9), 
CXL10_HUMAN (P02778), CXL10_MACMU (Q8MIZ1), CXL10_MACNE (Q865F5), 
CXL10_MOUSE (P17515), CXL10_RAT   (P48973), CXL11_BOVIN (A9QWQ1), 
CXL11_HUMAN (O14625), CXL11_MOUSE (Q9JHH5), CXL13_HUMAN (O43927), 
CXL13_MOUSE (O55038), CXL15_MOUSE (Q9WVL7), GRO2_RABIT  (P47854), 
GROA_BOVIN  (O46676), GROA_CAVPO  (O55235), GROA_CRIGR  (P09340), 
GROA_HUMAN  (P09341), GROA_MOUSE  (P12850), GROA_RAT    (P14095), 
GROA_SHEEP  (O46678), GROB_BOVIN  (O46677), GROG_BOVIN  (O46675), 
IL8_BOVIN   (P79255), IL8_CANFA   (P41324), IL8_CAVPO   (P49113), 
IL8_CERAT   (P46653), IL8_CHICK   (P08317), IL8_DASNO   (Q102R3), 
IL8_FELCA   (Q9XSX5), IL8_HORSE   (O62812), IL8_HUMAN   (P10145), 
IL8_MACMU   (P67813), IL8_MACNE   (P67814), IL8_PIG     (P26894), 
IL8_RABIT   (P19874), IL8_SHEEP   (P36925), IL8_TURTR   (Q7YRB5), 
PF4V_HUMAN  (P10720), PLF4_BOVIN  (P02777), PLF4_HUMAN  (P02776), 
PLF4_MOUSE  (Q9Z126), PLF4_PIG    (P30034), PLF4_RAT    (P06765), 
PLF4_SHEEP  (P30035)
» More

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

CXL14_HUMAN (O95715), CXL14_MOUSE (Q9WUQ5), CXL16_BOVIN (Q29RT9), 
CXL16_HUMAN (Q9H2A7), CXL16_MOUSE (Q8BSU2), CXL16_PIG   (Q9GKE2), 
CXL16_RAT   (Q6AXU5), SDF1_FELCA  (O62657), SDF1_HUMAN  (P48061), 
SDF1_MOUSE  (P40224), SDF1_XENLA  (Q8UUJ9), SDF1_XENTR  (Q5EBF6), 
VCC1_BOVIN  (A4IFR0), VCC1_HUMAN  (Q6UXB2), VCC1_MOUSE  (Q5UW37)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

GRO1_RABIT  (P30782), PLF4_RABIT  (P83470)

		

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