Entry: PS00471

General information about the entry

Entry name [info] SMALL_CYTOKINES_CXC
Accession [info] PS00471
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); APR-2006 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00434

Name and characterization of the entry

Description [info] Small cytokines (intercrine/chemokine) C-x-C subfamily signature.
Pattern [info]
C-x-C-[LIVMS]-x(4,6)-[LIVMFY]-x(2)-[RKSEQNA]-x-[LIVM]-x(2)-[LIVMA]-x(5)-
[STAG]-x(2)-C-x(3)-[EQ]-[LIVM](2)-x(9,10)-C-[LV]-[DN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 64 in 64 different sequences
Number of true positive hits 64 in 64 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 81.01 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 16
Site [info] disulfide at position 21
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

AMC2_PIG    (P22952), AMC_RABIT   (P82535), CXCL2_HUMAN (P19875), 
CXCL2_MOUSE (P10889), CXCL2_RAT   (P30348), CXCL3_HUMAN (P19876), 
CXCL3_MOUSE (Q6W5C0), CXCL3_RAT   (Q10746), CXCL5_HUMAN (P42830), 
CXCL5_MOUSE (P50228), CXCL5_RAT   (P97885), CXCL6_BOVIN (P80221), 
CXCL6_HORSE (Q8MIN2), CXCL6_HUMAN (P80162), CXCL7_HUMAN (P02775), 
CXCL7_PIG   (P43030), CXCL9_BOVIN (A9QWP9), CXCL9_HUMAN (Q07325), 
CXCL9_MOUSE (P18340), CXL10_BOVIN (Q2KIQ8), CXL10_CANFA (Q5KSV9), 
CXL10_HUMAN (P02778), CXL10_MACMU (Q8MIZ1), CXL10_MACNE (Q865F5), 
CXL10_MOUSE (P17515), CXL10_RAT   (P48973), CXL11_BOVIN (A9QWQ1), 
CXL11_HUMAN (O14625), CXL11_MOUSE (Q9JHH5), CXL13_HUMAN (O43927), 
CXL13_MOUSE (O55038), CXL15_MOUSE (Q9WVL7), GRO2_RABIT  (P47854), 
GROA_BOVIN  (O46676), GROA_CAVPO  (O55235), GROA_CRIGR  (P09340), 
GROA_HUMAN  (P09341), GROA_MOUSE  (P12850), GROA_RAT    (P14095), 
GROA_SHEEP  (O46678), GROB_BOVIN  (O46677), GROG_BOVIN  (O46675), 
IL8_BOVIN   (P79255), IL8_CANFA   (P41324), IL8_CAVPO   (P49113), 
IL8_CERAT   (P46653), IL8_CHICK   (P08317), IL8_DASNO   (Q102R3), 
IL8_FELCA   (Q9XSX5), IL8_HORSE   (O62812), IL8_HUMAN   (P10145), 
IL8_MACMU   (P67813), IL8_MACNE   (P67814), IL8_PIG     (P26894), 
IL8_RABIT   (P19874), IL8_SHEEP   (P36925), IL8_TURTR   (Q7YRB5), 
PF4V_HUMAN  (P10720), PLF4_BOVIN  (P02777), PLF4_HUMAN  (P02776), 
PLF4_MOUSE  (Q9Z126), PLF4_PIG    (P30034), PLF4_RAT    (P06765), 
PLF4_SHEEP  (P30035)
» More

UniProtKB/Swiss-Prot
False negative sequences
15 sequences

CXL14_HUMAN (O95715), CXL14_MOUSE (Q9WUQ5), CXL16_BOVIN (Q29RT9), 
CXL16_HUMAN (Q9H2A7), CXL16_MOUSE (Q8BSU2), CXL16_PIG   (Q9GKE2), 
CXL16_RAT   (Q6AXU5), SDF1_FELCA  (O62657), SDF1_HUMAN  (P48061), 
SDF1_MOUSE  (P40224), SDF1_XENLA  (Q8UUJ9), SDF1_XENTR  (Q5EBF6), 
VCC1_BOVIN  (A4IFR0), VCC1_HUMAN  (Q6UXB2), VCC1_MOUSE  (Q5UW37)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

GRO1_RABIT  (P30782), PLF4_RABIT  (P83470)

		
PDB
[Detailed view]
30 PDB

1F9P; 1F9Q; 1F9R; 1F9S; 1IL8; 1ILP; 1ILQ; 1MGS; 1MI2; 1MSG; 1MSH; 1NAP; 1O7Y; 1O7Z; 1O80; 1PFM; 1PFN; 1PLF; 1QE6; 1QNK; 1RHP; 1RJT; 1ROD; 1TVX; 2IL8; 2MGS; 2R3Z; 3IL8; 3N52; 4HSV
» More

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