Entry: PS00471

General information about the entry

Entry name [info] SMALL_CYTOKINES_CXC
Accession [info] PS00471
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); APR-2006 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00434

Name and characterization of the entry

Description [info] Small cytokines (intercrine/chemokine) C-x-C subfamily signature.
Pattern [info]
C-x-C-[LIVMS]-x(4,6)-[LIVMFY]-x(2)-[RKSEQNA]-x-[LIVM]-x(2)-[LIVMA]-x(5)-
[STAG]-x(2)-C-x(3)-[EQ]-[LIVM](2)-x(9,10)-C-[LV]-[DN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 65 in 65 different sequences
Number of true positive hits 65 in 65 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 16
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 80.25 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 16
Site [info] disulfide at position 21
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
65 sequences

AMC2_PIG    (P22952    ), AMC_RABIT   (P82535    ), CX116_DANRE (B0R191    ), 
CXCL2_HUMAN (P19875    ), CXCL2_MOUSE (P10889    ), CXCL2_RAT   (P30348    ), 
CXCL3_HUMAN (P19876    ), CXCL3_MOUSE (Q6W5C0    ), CXCL3_RAT   (Q10746    ), 
CXCL5_HUMAN (P42830    ), CXCL5_MOUSE (P50228    ), CXCL5_RAT   (P97885    ), 
CXCL6_BOVIN (P80221    ), CXCL6_HORSE (Q8MIN2    ), CXCL6_HUMAN (P80162    ), 
CXCL7_HUMAN (P02775    ), CXCL7_PIG   (P43030    ), CXCL9_BOVIN (A9QWP9    ), 
CXCL9_HUMAN (Q07325    ), CXCL9_MOUSE (P18340    ), CXL10_BOVIN (Q2KIQ8    ), 
CXL10_CANLF (Q5KSV9    ), CXL10_HUMAN (P02778    ), CXL10_MACMU (Q8MIZ1    ), 
CXL10_MACNE (Q865F5    ), CXL10_MOUSE (P17515    ), CXL10_RAT   (P48973    ), 
CXL11_BOVIN (A9QWQ1    ), CXL11_HUMAN (O14625    ), CXL11_MOUSE (Q9JHH5    ), 
CXL13_HUMAN (O43927    ), CXL13_MOUSE (O55038    ), CXL15_MOUSE (Q9WVL7    ), 
GRO2_RABIT  (P47854    ), GROA_BOVIN  (O46676    ), GROA_CAVPO  (O55235    ), 
GROA_CRIGR  (P09340    ), GROA_HUMAN  (P09341    ), GROA_MOUSE  (P12850    ), 
GROA_RAT    (P14095    ), GROA_SHEEP  (O46678    ), GROB_BOVIN  (O46677    ), 
GROG_BOVIN  (O46675    ), IL8_BOVIN   (P79255    ), IL8_CANLF   (P41324    ), 
IL8_CAVPO   (P49113    ), IL8_CERAT   (P46653    ), IL8_CHICK   (P08317    ), 
IL8_DASNO   (Q102R3    ), IL8_FELCA   (Q9XSX5    ), IL8_HORSE   (O62812    ), 
IL8_HUMAN   (P10145    ), IL8_MACMU   (P67813    ), IL8_MACNE   (P67814    ), 
IL8_PIG     (P26894    ), IL8_RABIT   (P19874    ), IL8_SHEEP   (P36925    ), 
IL8_TURTR   (Q7YRB5    ), PF4V_HUMAN  (P10720    ), PLF4_BOVIN  (P02777    ), 
PLF4_HUMAN  (P02776    ), PLF4_MOUSE  (Q9Z126    ), PLF4_PIG    (P30034    ), 
PLF4_RAT    (P06765    ), PLF4_SHEEP  (P30035    )
» more

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

CX111_DANRE (A0A0R4INB9), CXL14_HUMAN (O95715    ), CXL14_MOUSE (Q9WUQ5    ), 
CXL16_BOVIN (Q29RT9    ), CXL16_HUMAN (Q9H2A7    ), CXL16_MOUSE (Q8BSU2    ), 
CXL16_PIG   (Q9GKE2    ), CXL16_RAT   (Q6AXU5    ), CXL17_BOVIN (A4IFR0    ), 
CXL17_HUMAN (Q6UXB2    ), CXL17_MOUSE (Q5UW37    ), SDF1_FELCA  (O62657    ), 
SDF1_HUMAN  (P48061    ), SDF1_MOUSE  (P40224    ), SDF1_XENLA  (Q8UUJ9    ), 
SDF1_XENTR  (Q5EBF6    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

GRO1_RABIT  (P30782    ), PLF4_RABIT  (P83470    )

		
PDB
[Detailed view]
38 PDB

1F9P; 1F9Q; 1F9R; 1F9S; 1IL8; 1ILP; 1ILQ; 1MGS; 1MI2; 1MSG; 1MSH; 1NAP; 1O7Y; 1O7Z; 1O80; 1PFM; 1PFN; 1PLF; 1QE6; 1QNK; 1RHP; 1RJT; 1ROD; 1TVX; 2IL8; 2MGS; 2R3Z; 3IL8; 3N52; 4HSV; 4R9W; 4R9Y; 4RAU; 4XDX; 4ZAI; 5CBA; 5CBE; 5D14
» more

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