Entry: PS00477

General information about the entry

Entry name [info] ALPHA_2_MACROGLOBULIN
Accession [info] PS00477
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); MAY-1991 (DATA UPDATE); APR-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00440

Name and characterization of the entry

Description [info] Alpha-2-macroglobulin family thiolester region signature.
Pattern [info]

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_06 which contains 548'586 sequence entries.

Total number of hits 47 in 47 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 89.36 %
Recall (true positives / (true positives + false negatives)) 87.50 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] thiolester at position 4
Site [info] thiolester at position 7
Version [info] 1

Cross-references [info]

True positive sequences
42 sequences

A1I3_RAT    (P14046), A1M_RAT     (Q63041), A2MG_BOVIN  (Q7SIH1), 
A2MG_HUMAN  (P01023), A2MG_PONAB  (Q5R4N8), A2MG_RAT    (P06238), 
A2ML1_HUMAN (A8K2U0), A2MP_MOUSE  (Q6GQT1), A2M_HOMAM   (P20737), 
A2M_MOUSE   (Q61838), A2M_OCTVU   (P30800), A2M_PACLE   (P20738), 
CD109_HUMAN (Q6YHK3), CD109_MOUSE (Q8R422), CO3_BOVIN   (Q2UVX4), 
CO3_CAVPO   (P12387), CO3_EPTBU   (P98094), CO3_HUMAN   (P01024), 
CO3_LETCA   (Q00685), CO3_MOUSE   (P01027), CO3_NAJNA   (Q01833), 
CO3_ONCMY   (P98093), CO3_PIG     (P01025), CO3_RABIT   (P12247), 
CO3_RAT     (P01026), CO4A_HUMAN  (P0C0L4), CO4B_HUMAN  (P0C0L5), 
CO4B_MOUSE  (P01029), CO4_BOVIN   (P01030), CO4_RAT     (P08649), 
CPMD8_HUMAN (Q8IZJ3), MUG1_MOUSE  (P28665), MUG1_RAT    (Q03626), 
MUG2_MOUSE  (P28666), MUG2_RAT    (Q6IE52), OVOS_ANAPL  (P20739), 
OVOS_MOUSE  (Q3UU35), PZP_HUMAN   (P20742), VCO31_AUSSU (Q0ZZJ6), 
VCO3_CROAD  (J3S836), VCO3_NAJKA  (Q91132), VCO3_OPHHA  (I2C090)
» More

False negative sequences
6 sequences

CO5_HUMAN   (P01031), CO5_MOUSE   (P06684), OVOS1_HUMAN (Q6IE37), 
» More

'Partial' sequences
5 sequences

CO3_XENLA   (P23667), CO4_CAVPO   (P19069), CO5_BOVIN   (P12082), 
CO5_PIG     (P01032), CO5_RAT     (P08650)
» More

False positive sequences
5 sequences

GALT5_HUMAN (Q7Z7M9), GALT5_MOUSE (Q8C102), GALT5_RAT   (O88422), 
» More

[Detailed view]
13 PDB

2A73; 2B39; 2HR0; 2I07; 2ICF; 2WII; 2WIN; 2XWB; 2XWJ; 3G6J; 3L5N; 4FXG; 4FXK
» More

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