Entry: PS00477

General information about the entry

Entry name [info] ALPHA_2_MACROGLOBULIN
Accession [info] PS00477
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); MAY-1991 (DATA UPDATE); OCT-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00440

Name and characterization of the entry

Description [info] Alpha-2-macroglobulin family thiolester region signature.
Pattern [info]

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_11 which contains 549'832 sequence entries.

Total number of hits 47 in 47 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 89.36 %
Recall (true positives / (true positives + false negatives)) 87.50 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] thiolester at position 4
Site [info] thiolester at position 7
Version [info] 1

Cross-references [info]

True positive sequences
42 sequences

A1I3_RAT    (P14046), A1M_RAT     (Q63041), A2MG_BOVIN  (Q7SIH1), 
A2MG_HUMAN  (P01023), A2MG_PONAB  (Q5R4N8), A2MG_RAT    (P06238), 
A2ML1_HUMAN (A8K2U0), A2MP_MOUSE  (Q6GQT1), A2M_HOMAM   (P20737), 
A2M_MOUSE   (Q61838), A2M_OCTVU   (P30800), A2M_PACLE   (P20738), 
CD109_HUMAN (Q6YHK3), CD109_MOUSE (Q8R422), CO3_BOVIN   (Q2UVX4), 
CO3_CAVPO   (P12387), CO3_EPTBU   (P98094), CO3_HUMAN   (P01024), 
CO3_LETCA   (Q00685), CO3_MOUSE   (P01027), CO3_NAJNA   (Q01833), 
CO3_ONCMY   (P98093), CO3_PIG     (P01025), CO3_RABIT   (P12247), 
CO3_RAT     (P01026), CO4A_HUMAN  (P0C0L4), CO4B_HUMAN  (P0C0L5), 
CO4B_MOUSE  (P01029), CO4_BOVIN   (P01030), CO4_RAT     (P08649), 
CPMD8_HUMAN (Q8IZJ3), MUG1_MOUSE  (P28665), MUG1_RAT    (Q03626), 
MUG2_MOUSE  (P28666), MUG2_RAT    (Q6IE52), OVOS_ANAPL  (P20739), 
OVOS_MOUSE  (Q3UU35), PZP_HUMAN   (P20742), VCO31_AUSSU (Q0ZZJ6), 
VCO3_CROAD  (J3S836), VCO3_NAJKA  (Q91132), VCO3_OPHHA  (I2C090)
» more

False negative sequences
6 sequences

CO5_HUMAN   (P01031), CO5_MOUSE   (P06684), OVOS1_HUMAN (Q6IE37), 
» more

'Partial' sequences
5 sequences

CO3_XENLA   (P23667), CO4_CAVPO   (P19069), CO5_BOVIN   (P12082), 
CO5_PIG     (P01032), CO5_RAT     (P08650)
» more

False positive sequences
5 sequences

GALT5_HUMAN (Q7Z7M9), GALT5_MOUSE (Q8C102), GALT5_RAT   (O88422), 
» more

[Detailed view]
14 PDB

2A73; 2B39; 2HR0; 2I07; 2ICF; 2WII; 2WIN; 2XWB; 2XWJ; 3G6J; 3L5N; 4FXG; 4FXK; 4XAM
» more

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