Entry: PS00477

General information about the entry

Entry name [info] ALPHA_2_MACROGLOBULIN
Accession [info] PS00477
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); MAY-1991 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00440

Name and characterization of the entry

Description [info] Alpha-2-macroglobulin family thiolester region signature.
Pattern [info]
[PG]-x-[GS]-C-[GA]-E-[EQ]-x-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 47 in 47 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 89.36 %
Recall (true positives / (true positives + false negatives)) 87.50 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] thiolester at position 4
Site [info] thiolester at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
42 sequences

A1I3_RAT    (P14046    ), A1M_RAT     (Q63041    ), A2MG_BOVIN  (Q7SIH1    ), 
A2MG_HUMAN  (P01023    ), A2MG_MOUSE  (Q6GQT1    ), A2MG_PONAB  (Q5R4N8    ), 
A2MG_RAT    (P06238    ), A2ML1_HUMAN (A8K2U0    ), A2M_HOMAM   (P20737    ), 
A2M_OCTVU   (P30800    ), A2M_PACLE   (P20738    ), CD109_HUMAN (Q6YHK3    ), 
CD109_MOUSE (Q8R422    ), CO3_BOVIN   (Q2UVX4    ), CO3_CAVPO   (P12387    ), 
CO3_EPTBU   (P98094    ), CO3_HUMAN   (P01024    ), CO3_LETCA   (Q00685    ), 
CO3_MOUSE   (P01027    ), CO3_NAJNA   (Q01833    ), CO3_ONCMY   (P98093    ), 
CO3_PIG     (P01025    ), CO3_RABIT   (P12247    ), CO3_RAT     (P01026    ), 
CO4A_HUMAN  (P0C0L4    ), CO4B_HUMAN  (P0C0L5    ), CO4B_MOUSE  (P01029    ), 
CO4_BOVIN   (P01030    ), CO4_RAT     (P08649    ), CPMD8_HUMAN (Q8IZJ3    ), 
MUG1_MOUSE  (P28665    ), MUG1_RAT    (Q03626    ), MUG2_MOUSE  (P28666    ), 
MUG2_RAT    (Q6IE52    ), OVOS_ANAPL  (P20739    ), OVOS_MOUSE  (Q3UU35    ), 
PZP_HUMAN   (P20742    ), PZP_MOUSE   (Q61838    ), VCO31_AUSSU (Q0ZZJ6    ), 
VCO3_CROAD  (J3S836    ), VCO3_NAJKA  (Q91132    ), VCO3_OPHHA  (I2C090    )
» more

UniProtKB/Swiss-Prot
False negative sequences
6 sequences

CO5_HUMAN   (P01031    ), CO5_MOUSE   (P06684    ), OVOS1_HUMAN (Q6IE37    ), 
OVOS2_HUMAN (Q6IE36    ), OVOS_CHICK  (P20740    ), VCO32_AUSSU (A0RZC6    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

CO3_XENLA   (P23667    ), CO4_CAVPO   (P19069    ), CO5_BOVIN   (P12082    ), 
CO5_PIG     (P01032    ), CO5_RAT     (P08650    )
» more

UniProtKB/Swiss-Prot
False positive sequences
5 sequences

GALT5_HUMAN (Q7Z7M9    ), GALT5_MOUSE (Q8C102    ), GALT5_RAT   (O88422    ), 
ISPE_CHLAB  (Q5L568    ), ISPE_CHLCV  (Q821X0    )
» more

PDB
[Detailed view]
13 PDB

2A73; 2B39; 2I07; 2ICF; 2WII; 2WIN; 2XWB; 2XWJ; 3G6J; 3L5N; 4FXG; 4FXK; 4XAM
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission