Entry: PS00477

Forthcoming changes to the profile format
General information about the entry

Entry name [info] ALPHA_2_MACROGLOBULIN
Accession [info] PS00477
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); MAY-1991 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00440

Name and characterization of the entry

Description [info] Alpha-2-macroglobulin family thiolester region signature.
Pattern [info]
[PG]-x-[GS]-C-[GA]-E-[EQ]-x-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 47 in 47 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 89.36 %
Recall (true positives / (true positives + false negatives)) 87.50 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] thiolester at position 4
Site [info] thiolester at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
42 sequences

A1I3_RAT    (P14046), A1M_RAT     (Q63041), A2MG_BOVIN  (Q7SIH1), 
A2MG_HUMAN  (P01023), A2MG_PONAB  (Q5R4N8), A2MG_RAT    (P06238), 
A2ML1_HUMAN (A8K2U0), A2MP_MOUSE  (Q6GQT1), A2M_HOMAM   (P20737), 
A2M_MOUSE   (Q61838), A2M_OCTVU   (P30800), A2M_PACLE   (P20738), 
CD109_HUMAN (Q6YHK3), CD109_MOUSE (Q8R422), CO3_BOVIN   (Q2UVX4), 
CO3_CAVPO   (P12387), CO3_EPTBU   (P98094), CO3_HUMAN   (P01024), 
CO3_LAMJA   (Q00685), CO3_MOUSE   (P01027), CO3_NAJNA   (Q01833), 
CO3_ONCMY   (P98093), CO3_PIG     (P01025), CO3_RABIT   (P12247), 
CO3_RAT     (P01026), CO4A_HUMAN  (P0C0L4), CO4B_HUMAN  (P0C0L5), 
CO4B_MOUSE  (P01029), CO4_BOVIN   (P01030), CO4_RAT     (P08649), 
CPMD8_HUMAN (Q8IZJ3), MUG1_MOUSE  (P28665), MUG1_RAT    (Q03626), 
MUG2_MOUSE  (P28666), MUG2_RAT    (Q6IE52), OVOS_ANAPL  (P20739), 
OVOS_MOUSE  (Q3UU35), PZP_HUMAN   (P20742), VCO31_AUSSU (Q0ZZJ6), 
VCO3_CROAD  (J3S836), VCO3_NAJKA  (Q91132), VCO3_OPHHA  (I2C090)
» More

UniProtKB/Swiss-Prot
False negative sequences
6 sequences

CO5_HUMAN   (P01031), CO5_MOUSE   (P06684), OVOS1_HUMAN (Q6IE37), 
OVOS2_HUMAN (Q6IE36), OVOS_CHICK  (P20740), VCO32_AUSSU (A0RZC6)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

CO3_XENLA   (P23667), CO4_CAVPO   (P19069), CO5_BOVIN   (P12082), 
CO5_PIG     (P01032), CO5_RAT     (P08650)
» More

UniProtKB/Swiss-Prot
False positive sequences
5 sequences

GALT5_HUMAN (Q7Z7M9), GALT5_MOUSE (Q8C102), GALT5_RAT   (O88422), 
ISPE_CHLAB  (Q5L568), ISPE_CHLCV  (Q821X0)
» More


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission