Entry: PS00478

Forthcoming changes to the profile format
General information about the entry

Entry name [info] LIM_DOMAIN_1
Accession [info] PS00478
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); DEC-2004 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00382

Name and characterization of the entry

Description [info] LIM zinc-binding domain signature.
Pattern [info]
C-x(2)-C-x(15,21)-[FYWHPCR]-H-x(2)-[CH]-x(2)-C-x(2)-C-x(3)-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 765 in 380 different sequences
Number of true positive hits 764 in 379 different sequences
Number of 'unknown' hits
Number of false positive hits 1
Number of false negative sequences 7
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.87 %
Recall (true positives / (true positives + false negatives)) 99.09 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Site [info] zinc at position 1
Site [info] zinc at position 3
Site [info] zinc at position 6
Site [info] zinc at position 8
Site [info] zinc at position 10
Site [info] zinc at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
379 sequences

ABLM1_HUMAN (O14639), ABLM1_MOUSE (Q8K4G5), ABLM2_HUMAN (Q6H8Q1), 
ABLM2_MOUSE (Q8BL65), ABLM2_RAT   (Q6KC51), ABLM3_HUMAN (O94929), 
ABLM3_MOUSE (Q69ZX8), AJUBA_BOVIN (E1BKA3), AJUBA_DROME (Q9VY77), 
AJUBA_HUMAN (Q96IF1), AJUBA_MOUSE (Q91XC0), AJUBA_RAT   (Q5U2Z2), 
APTE_DROME  (P29673), AWH_DROME   (Q8IRC7), CRIP1_BOVIN (Q56K04), 
CRIP1_HUMAN (P50238), CRIP1_MOUSE (P63254), CRIP1_RAT   (P63255), 
CRIP2_BOVIN (Q0VFX8), CRIP2_HUMAN (P52943), CRIP2_MOUSE (Q9DCT8), 
CRIP2_PONAB (Q5R7Y1), CRIP2_RAT   (P36201), CRIP3_HUMAN (Q6Q6R5), 
CRIP3_MOUSE (Q6Q6R3), CSRP1_BOVIN (Q3MHY1), CSRP1_CHICK (P67966), 
CSRP1_COTJA (P67967), CSRP1_HUMAN (P21291), CSRP1_MOUSE (P97315), 
CSRP1_PONAB (Q5RCT4), CSRP1_RAT   (P47875), CSRP2_BOVIN (Q32LE9), 
CSRP2_CHICK (P50460), CSRP2_COTJA (Q05158), CSRP2_HUMAN (Q16527), 
CSRP2_MOUSE (P97314), CSRP2_RAT   (Q62908), CSRP3_BOVIN (Q4U0T9), 
CSRP3_HUMAN (P50461), CSRP3_MOUSE (P50462), CSRP3_RAT   (P50463), 
DA1_ARATH   (P0C7Q8), DAR1_ARATH  (Q8W4F0), DAR2_ARATH  (Q0WSN2), 
DAR4_ARATH  (Q9FKN7), DAR5_ARATH  (Q84WJ0), DAR6_ARATH  (Q9FJX8), 
DAR7_ARATH  (Q9FJX9), ESN_DROME   (Q9U1I1), ESN_DROPS   (Q292U5), 
FBLI1_BOVIN (Q1JQB5), FBLI1_HUMAN (Q8WUP2), FBLI1_MOUSE (Q71FD7), 
FBLI1_PONAB (Q5REN1), FHL1_HUMAN  (Q13642), FHL1_MOUSE  (P97447), 
FHL1_RAT    (Q9WUH4), FHL2_BOVIN  (Q2KI95), FHL2_HUMAN  (Q14192), 
FHL2_MOUSE  (O70433), FHL2_RAT    (O35115), FHL3_BOVIN  (Q3ZBI6), 
FHL3_HUMAN  (Q13643), FHL3_MOUSE  (Q9R059), FHL5_BOVIN  (Q2YDK0), 
FHL5_HUMAN  (Q5TD97), FHL5_MACFA  (Q4R7A4), FHL5_MOUSE  (Q9WTX7), 
FHL5_RAT    (Q6AXT1), HM14_CAEEL  (P20271), ISL1_CHICK  (P50211), 
ISL1_DANRE  (P53405), ISL1_HUMAN  (P61371), ISL1_MESAU  (P61373), 
ISL1_MOUSE  (P61372), ISL1_RAT    (P61374), ISL2A_DANRE (P53406), 
ISL2A_ONCTS (P53408), ISL2B_DANRE (P53407), ISL2B_ONCTS (P50212), 
ISL2_CHICK  (P53410), ISL2_HUMAN  (Q96A47), ISL2_MOUSE  (Q9CXV0), 
ISL2_RAT    (P50480), ISL3_ONCTS  (P53409), LASP1_BOVIN (Q3B7M5), 
LASP1_DROME (Q8I7C3), LASP1_HUMAN (Q14847), LASP1_MOUSE (Q61792), 
LASP1_PONAB (Q5R5W0), LASP1_RABIT (O77506), LASP1_RAT   (Q99MZ8), 
LDB3_HUMAN  (O75112), LDB3_MOUSE  (Q9JKS4), LHX1_CHICK  (P53411), 
LHX1_DANRE  (Q90476), LHX1_HUMAN  (P48742), LHX1_MESAU  (P63008), 
LHX1_MOUSE  (P63006), LHX1_PANTR  (Q5IS44), LHX1_RAT    (P63007), 
LHX1_SAIBB  (Q5IS89), LHX1_XENLA  (P29674), LHX2_HUMAN  (P50458), 
LHX2_MOUSE  (Q9Z0S2), LHX2_RAT    (P36198), LHX3_CHICK  (P53412), 
LHX3_DANRE  (Q90421), LHX3_HUMAN  (Q9UBR4), LHX3_MOUSE  (P50481), 
LHX3_PIG    (O97581), LHX3_XENLA  (P36200), LHX4_HUMAN  (Q969G2), 
LHX4_MOUSE  (P53776), LHX5_DANRE  (P52889), LHX5_HUMAN  (Q9H2C1), 
LHX5_MOUSE  (P61375), LHX5_RAT    (P61376), LHX5_XENLA  (P37137), 
LHX6_HUMAN  (Q9UPM6), LHX6_MOUSE  (Q9R1R0), LHX8_HUMAN  (Q68G74), 
LHX8_MOUSE  (O35652), LHX9_ASTFA  (A2I8Z7), LHX9_BOVIN  (A0JNI8), 
LHX9_CHICK  (Q90881), LHX9_DANRE  (Q1LWV4), LHX9_GLARU  (A2PZF9), 
LHX9_HUMAN  (Q9NQ69), LHX9_MOUSE  (Q9WUH2), LHX9_RAT    (Q80W90), 
LHX9_XENLA  (Q68EY3), LIM3L_HUMAN (P0CW20), LIMA1_HUMAN (Q9UHB6), 
LIMA1_MOUSE (Q9ERG0), LIMA1_PIG   (B0KYV5), LIMA_DICDI  (Q54QR1), 
LIMB_DICDI  (Q54NW4), LIMC1_HUMAN (Q9UPQ0), LIMC1_MOUSE (Q3UH68), 
LIMC1_XENLA (Q3KQW7), LIMCH_DICDI (Q55GV9), LIMC_DICDI  (Q9BIW5), 
LIMD1_BOVIN (G5E5X0), LIMD1_HUMAN (Q9UGP4), LIMD1_MOUSE (Q9QXD8), 
LIMD1_RAT   (B5DEH0), LIMD1_XENLA (Q06BR1), LIMD1_XENTR (B7ZUL2), 
LIMD2_BOVIN (Q1LZA7), LIMD2_HUMAN (Q9BT23), LIMD2_MOUSE (Q8BGB5), 
LIMD2_RAT   (Q4KM31), LIMD_DICDI  (Q9BIW4), LIME_DICDI  (O60952), 
LIMF_DICDI  (Q86I44), LIMG_DICDI  (Q55DS4), LIMK1_CHICK (Q8QFP8), 
LIMK1_DROME (Q8IR79), LIMK1_HUMAN (P53667), LIMK1_MOUSE (P53668), 
LIMK1_RAT   (P53669), LIMK1_XENLA (O42565), LIMK2_BOVIN (Q32L23), 
LIMK2_CHICK (P53666), LIMK2_HUMAN (P53671), LIMK2_MOUSE (O54785), 
LIMK2_RAT   (P53670), LIMKA_DICDI (Q54L00), LIMKB_DICDI (P0CD62), 
LIMS1_HUMAN (P48059), LIMS1_MOUSE (Q99JW4), LIMS2_BOVIN (Q2KJ33), 
LIMS2_HUMAN (Q7Z4I7), LIMS2_MOUSE (Q91XD2), LIMS3_HUMAN (P0CW19), 
LIN11_CAEEL (P20154), LMCD1_BOVIN (Q17QE2), LMCD1_HUMAN (Q9NZU5), 
LMCD1_MOUSE (Q8VEE1), LMCD1_PIG   (Q5PXT2), LMO3_BOVIN  (Q2KIA3), 
LMO3_DANRE  (Q503U0), LMO3_HUMAN  (Q8TAP4), LMO3_MOUSE  (Q8BZL8), 
LMO3_PONAB  (Q5RBW7), LMO3_RAT    (Q99MB5), LMO3_XENLA  (Q9YH16), 
LMO41_XENTR (Q5FVB2), LMO42_XENTR (Q6DJ06), LMO4A_XENLA (Q8AW92), 
LMO4B_XENLA (Q801P0), LMO4_BOVIN  (Q3SWZ8), LMO4_HUMAN  (P61968), 
LMO4_MOUSE  (P61969), LMO7_HUMAN  (Q8WWI1), LMX1A_HUMAN (Q8TE12), 
LMX1A_MESAU (Q04650), LMX1A_MOUSE (Q9JKU8), LMX1B_CHICK (P53413), 
LMX1B_HUMAN (O60663), LMX1B_MESAU (Q60564), LMX1B_MOUSE (O88609), 
LMX1B_XENLA (Q8UVR3), LNEBL_MOUSE (Q9DC07), LPP_CHICK   (Q5F464), 
LPP_HUMAN   (Q93052), LPP_MOUSE   (Q8BFW7), LPP_RAT     (Q5XI07), 
LPXN_HUMAN  (O60711), LPXN_MOUSE  (Q99N69), LPXN_RABIT  (Q9N261), 
LRG1_YEAST  (P35688), MCA2B_DANRE (F1RA39), MCA3A_DANRE (F1QH17), 
MCA3B_DANRE (F1QWK4), MEC3_CAEBR  (P34764), MEC3_CAEEL  (P09088), 
MEC3_CAERE  (P34765), MICA1_BOVIN (F1MH07), MICA1_DANRE (E7F9T0), 
MICA1_HUMAN (Q8TDZ2), MICA1_MOUSE (Q8VDP3), MICA1_RAT   (D3ZBP4), 
MICA2_BOVIN (F1MF74), MICA2_HUMAN (O94851), MICA2_MOUSE (Q8BML1), 
MICA2_RAT   (D4A1F2), MICA2_XENTR (F6QZ15), MICA3_BOVIN (G3MWR8), 
MICA3_HUMAN (Q7RTP6), MICA3_MOUSE (Q8CJ19), MILK1_BOVIN (E1BBG2), 
MILK1_HUMAN (Q8N3F8), MILK1_MOUSE (Q8BGT6), MILK1_RAT   (D3ZQL6), 
MILK2_HUMAN (Q8IY33), MILK2_MOUSE (Q3TN34), MILK2_RAT   (D3ZEN0), 
MLP1_DROME  (P53777), MLP2_DROME  (Q24400), NRAP_HUMAN  (Q86VF7), 
NRAP_MOUSE  (Q80XB4), PAXB_DICDI  (Q8MML5), PAXI_CHICK  (P49024), 
PAXI_HUMAN  (P49023), PAXI_MOUSE  (Q8VI36), PAXI_PONAB  (Q5R7I1), 
PAXI_RAT    (Q66H76), PDLI1_BOVIN (Q5E9E1), PDLI1_HUMAN (O00151), 
PDLI1_MOUSE (O70400), PDLI1_RAT   (P52944), PDLI2_BOVIN (Q3T0C8), 
PDLI2_HUMAN (Q96JY6), PDLI2_MACFA (Q9GKU1), PDLI2_MOUSE (Q8R1G6), 
PDLI2_RAT   (Q6AYD6), PDLI3_BOVIN (Q3SYZ8), PDLI3_CHICK (Q9PU47), 
PDLI3_HUMAN (Q53GG5), PDLI3_MOUSE (O70209), PDLI3_PIG   (Q6QGC0), 
PDLI3_RAT   (Q66HS7), PDLI3_XENLA (Q6GLJ6), PDLI4_BOVIN (Q3T005), 
PDLI4_CHICK (Q9PW72), PDLI4_HUMAN (P50479), PDLI4_MOUSE (P70271), 
PDLI4_RAT   (P36202), PDLI5_HUMAN (Q96HC4), PDLI5_MOUSE (Q8CI51), 
PDLI5_RAT   (Q62920), PDLI7_BOVIN (Q3SX40), PDLI7_CHICK (Q679P3), 
PDLI7_DANRE (Q6P7E4), PDLI7_HUMAN (Q9NR12), PDLI7_MOUSE (Q3TJD7), 
PDLI7_RAT   (Q9Z1Z9), PDLI7_XENLA (Q6INU3), PIN2_CAEEL  (Q19157), 
PRI1A_XENLA (Q90Z06), PRI1B_XENLA (Q90WV2), PRIC1_AEDAE (Q174I2), 
PRIC1_ANOGA (Q7QJT4), PRIC1_DROME (A1Z6W3), PRIC1_DROPS (Q292U2), 
PRIC1_HUMAN (Q96MT3), PRIC1_MOUSE (Q3U5C7), PRIC1_RAT   (Q71QF9), 
PRIC1_XENTR (Q28FG2), PRIC2_HUMAN (Q7Z3G6), PRIC2_MOUSE (Q80Y24), 
PRIC3_HUMAN (O43900), PRIC3_MOUSE (Q80VL3), PRIC4_HUMAN (Q2TBC4), 
PXL1_CAEEL  (Q09476), PXL1_YEAST  (P36166), RBTN1_BOVIN (Q0P5B3), 
RBTN1_DANRE (Q8JFQ2), RBTN1_HUMAN (P25800), RBTN1_MOUSE (Q924W9), 
RBTN1_XENLA (Q3B8H4), RBTN2_BOVIN (Q1LZ94), RBTN2_DANRE (Q9PTJ3), 
RBTN2_HUMAN (P25791), RBTN2_MOUSE (P25801), RBTN2_XENLA (Q90XH3), 
RBTN2_XENTR (Q5M8V8), RGA1_SCHPO  (O43052), RGA1_YEAST  (P39083), 
RGA2_YEAST  (Q06407), RGA3_SCHPO  (O14014), RGA4_SCHPO  (O74360), 
SCEL_HUMAN  (O95171), SCEL_MOUSE  (Q9EQG3), SF3_HELAN   (P29675), 
TES_AOTNA   (Q07DW1), TES_ATEAB   (Q00PK1), TES_ATEGE   (Q09YL5), 
TES_BOVIN   (Q2YDE9), TES_CALJA   (Q2QLG8), TES_CALMO   (Q2QLC3), 
TES_CANFA   (A0M8U6), TES_CHICK   (Q90YH9), TES_CHLAE   (Q2IBA3), 
TES_COLGU   (Q07DZ4), TES_DASNO   (Q07E51), TES_EULMM   (Q2IBH0), 
TES_FELCA   (A0M8S5), TES_HORSE   (Q2QLB2), TES_HUMAN   (Q9UGI8), 
TES_LOXAF   (Q108U9), TES_MICMU   (Q2QL92), TES_MONDO   (Q2QLA1), 
TES_MOUSE   (P47226), TES_MUNMU   (Q09YK3), TES_MUNRE   (Q07DX3), 
TES_MUSPF   (Q07E27), TES_NEONE   (Q07E40), TES_NOMLE   (Q07DY3), 
TES_OTOGA   (Q2QLH9), TES_PANTR   (Q2QLF4), TES_PAPAN   (A0M8R4), 
TES_PIG     (Q2QLE3), TES_PONAB   (Q5RC52), TES_RABIT   (Q09YN8), 
TES_RAT     (Q2LAP6), TES_RHIFE   (Q2IBC3), TES_SAIBB   (Q09YI0), 
TES_SHEEP   (Q09YJ2), TES_XENLA   (Q7ZXE9), TES_XENTR   (Q6DIR5), 
TGFI1_BOVIN (Q3MHZ4), TGFI1_HUMAN (O43294), TGFI1_MOUSE (Q62219), 
TGFI1_RAT   (Q99PD6), TGFI1_XENLA (Q2TCH4), TRIP6_BOVIN (Q3SX26), 
TRIP6_HUMAN (Q15654), TRIP6_MOUSE (Q9Z1Y4), TTX3_CAEEL  (G5EE86), 
UNC97_CAEEL (P50464), WTIP_DANRE  (A8DZE6), WTIP_HUMAN  (A6NIX2), 
WTIP_MOUSE  (Q7TQJ8), WTIP_XENLA  (A9LS46), XIRP2_MOUSE (Q4U4S6), 
Y6787_DICDI (Q55BI0), YOCC_SCHPO  (O74398), ZASP_DROME  (A1ZA47), 
ZN185_HUMAN (O15231), ZN185_MOUSE (Q62394), ZYX_CHICK   (Q04584), 
ZYX_HUMAN   (Q15942), ZYX_MOUSE   (Q62523), ZYX_XENLA   (A5H447), 
ZYX_XENTR   (Q0VA45)
» More

UniProtKB/Swiss-Prot
False negative sequences
7 sequences

ADCE_DICDI  (Q55GN8), LASP1_CAEEL (P34416), LHX3_HALRO  (Q25132), 
MICAL_DROME (Q86BA1), Y2098_DICDI (Q55A66), YD266_YEAST (Q05580), 
YJ01_SCHPO  (Q76PD2)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

LASP1_PIG   (P80171)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

YEMC_SCHPO  (O14033)

		
PDB
[Detailed view]
61 PDB

1A7I; 1B8T; 1CTL; 1CXX; 1G47; 1IBI; 1IML; 1J2O; 1M3V; 1NYP; 1QLI; 1RUT; 1U5S; 1V6G; 1WIG; 1WYH; 1X3H; 1X4K; 1X4L; 1X61; 1X62; 1X63; 1X64; 1X68; 1X6A; 2CO8; 2COR; 2CU8; 2CUP; 2CUQ; 2CUR; 2D8X; 2D8Y; 2D8Z; 2DFY; 2DJ7; 2DLO; 2EGQ; 2EHE; 2JTN; 2KBX; 2L4Z; 2L6Y; 2L6Z; 2LXD; 2LZU; 2MIU; 2O10; 2O13; 2RGT; 2XJY; 2XJZ; 2XQN; 2YPA; 3F6Q; 3IXE; 3MMK; 4HI8; 4HI9; 4JCJ; 4KFZ
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission