Entry: PS00482

General information about the entry

Entry name [info] DIHYDROOROTASE_1
Accession [info] PS00482
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); JUL-1999 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00401

Name and characterization of the entry

Description [info] Dihydroorotase signature 1.
Pattern [info]
D-[LIVMFYWSAP]-H-[LIVA]-H-[LIVF]-[RN]-x-[PGANF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 295 in 295 different sequences
Number of true positive hits 281 in 281 different sequences
Number of 'unknown' hits 0
Number of false positive hits 14 in 14 different sequences
Number of false negative sequences 64
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 95.25 %
Recall (true positives / (true positives + false negatives)) 81.45 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] zinc(?) at position 3
Site [info] zinc(?) at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
281 sequences

ALN1_DICDI  (Q54SV3    ), ALN2_DICDI  (Q55C91    ), ALN_LITCT   (P40757    ), 
ALN_YEAST   (P32375    ), PYR1_DICDI  (P20054    ), PYR1_DROME  (P05990    ), 
PYR1_HUMAN  (P27708    ), PYR1_MESAU  (P08955    ), PYR1_MOUSE  (B2RQC6    ), 
PYR1_SQUAC  (Q91437    ), PYRC_ACAM1  (B0CF78    ), PYRC_ACIAD  (Q6FD29    ), 
PYRC_ACIB3  (B7GX48    ), PYRC_ACIB5  (B7I9G6    ), PYRC_ACIBC  (B2HWF6    ), 
PYRC_ACIBS  (B0VKW9    ), PYRC_ACIBT  (A3M3K3    ), PYRC_ACIBY  (B0VAC1    ), 
PYRC_ACISJ  (A1WC79    ), PYRC_AGRFC  (Q8UI99    ), PYRC_AGRRK  (B9J8H5    ), 
PYRC_AGRVS  (B9JQV9    ), PYRC_ALCBS  (Q0VNK6    ), PYRC_ALISL  (B6ER91    ), 
PYRC_ALKEH  (Q0AB36    ), PYRC_ANAD2  (B8JAE8    ), PYRC_ANADE  (Q2IIB0    ), 
PYRC_ANAPZ  (Q2GL89    ), PYRC_ANASK  (B4UDQ2    ), PYRC_ANOFW  (B7GFA5    ), 
PYRC_AQUAE  (O66990    ), PYRC_ARATH  (O04904    ), PYRC_ARCFU  (O28034    ), 
PYRC_AROAE  (Q5P6Y5    ), PYRC_AZOSB  (A1K3T5    ), PYRC_AZOVD  (C1DQV1    ), 
PYRC_BACAA  (C3P658    ), PYRC_BACAC  (C3L738    ), PYRC_BACAH  (A0RHR0    ), 
PYRC_BACAN  (Q81WF0    ), PYRC_BACC0  (B7JJX5    ), PYRC_BACC1  (Q732I1    ), 
PYRC_BACC2  (B7IUP8    ), PYRC_BACC3  (C1EPQ2    ), PYRC_BACC4  (B7H6M4    ), 
PYRC_BACC7  (B7HLM2    ), PYRC_BACCL  (P46538    ), PYRC_BACCN  (A7GRL3    ), 
PYRC_BACCQ  (B9IVW5    ), PYRC_BACCR  (Q819S1    ), PYRC_BACCZ  (Q636D8    ), 
PYRC_BACHD  (Q9K9V7    ), PYRC_BACHK  (Q6HES6    ), PYRC_BACLD  (Q65JU9    ), 
PYRC_BACP2  (A8FD15    ), PYRC_BACSK  (Q5WFJ0    ), PYRC_BACSU  (P25995    ), 
PYRC_BACWK  (A9VTC8    ), PYRC_BREBN  (C0ZG41    ), PYRC_BUCA5  (B8D9C1    ), 
PYRC_BUCAI  (P57416    ), PYRC_BUCAP  (Q8K9L2    ), PYRC_BUCAT  (B8D7M3    ), 
PYRC_CARHZ  (Q3AC01    ), PYRC_CHESB  (Q11IA4    ), PYRC_CITK8  (A8AI14    ), 
PYRC_CORGL  (Q8NQ39    ), PYRC_CROS8  (A7MG30    ), PYRC_CUPMC  (Q1LRD4    ), 
PYRC_CUPNH  (Q0KEE2    ), PYRC_CUPPJ  (Q475T7    ), PYRC_CUPTR  (B2AH54    ), 
PYRC_DELAS  (A9BSM4    ), PYRC_DESAH  (C0QJ54    ), PYRC_DESPS  (Q6AS41    ), 
PYRC_DESRM  (A4J556    ), PYRC_ECO24  (A7ZKG7    ), PYRC_ECO27  (B7UP76    ), 
PYRC_ECO45  (B7MIK3    ), PYRC_ECO55  (B7LFZ6    ), PYRC_ECO57  (Q8X8N8    ), 
PYRC_ECO5E  (B5YVT2    ), PYRC_ECO7I  (B7NL72    ), PYRC_ECO81  (B7MTJ3    ), 
PYRC_ECO8A  (B7M937    ), PYRC_ECOBW  (C4ZS02    ), PYRC_ECODH  (B1X9H5    ), 
PYRC_ECOHS  (A7ZZ20    ), PYRC_ECOK1  (A1A9V7    ), PYRC_ECOL5  (Q0TJ12    ), 
PYRC_ECOL6  (Q8FIR2    ), PYRC_ECOLC  (B1IV40    ), PYRC_ECOLI  (P05020    ), 
PYRC_ECOLU  (B7NAT7    ), PYRC_ECOSE  (B6I9D9    ), PYRC_ECOSM  (B1LIU8    ), 
PYRC_ECOUT  (Q1RD95    ), PYRC_EHRCJ  (Q3YRI2    ), PYRC_EHRCR  (Q2GH90    ), 
PYRC_ENT38  (A4W975    ), PYRC_ENTFA  (Q834E0    ), PYRC_ERWT9  (B2VDJ8    ), 
PYRC_ERYLH  (Q2NCC9    ), PYRC_ESCF3  (B7LT74    ), PYRC_GEOBB  (B5EB50    ), 
PYRC_GEODF  (B9M4S4    ), PYRC_GEOKA  (Q5L0U5    ), PYRC_GEOLS  (B3E3I1    ), 
PYRC_GEOMG  (Q39US3    ), PYRC_GEOSL  (Q74DP4    ), PYRC_GEOSM  (C6DZ51    ), 
PYRC_GEOSW  (C5D8P8    ), PYRC_GEOTN  (A4IM31    ), PYRC_GEOUR  (A5GF42    ), 
PYRC_HAHCH  (Q2SCE3    ), PYRC_HALHL  (A1WV00    ), PYRC_HALSA  (Q9HMH9    ), 
PYRC_HELAH  (Q17W17    ), PYRC_HELHP  (Q7VIJ1    ), PYRC_HELP2  (B6JLG3    ), 
PYRC_HELPH  (Q1CTU5    ), PYRC_HELPJ  (Q9ZLQ0    ), PYRC_HELPS  (B2UTP7    ), 
PYRC_HELPY  (P56465    ), PYRC_IDILO  (Q5QWC6    ), PYRC_JANSC  (Q28RK3    ), 
PYRC_LACLA  (Q9CGM7    ), PYRC_LACPL  (P77884    ), PYRC_LARHH  (C1D672    ), 
PYRC_LEPCP  (B1XWS5    ), PYRC_LISIN  (Q92AH1    ), PYRC_LISMC  (C1KWD6    ), 
PYRC_LISMF  (Q71YH9    ), PYRC_LISMH  (B8DDR5    ), PYRC_LISMO  (Q8Y663    ), 
PYRC_LISW6  (A0AJU2    ), PYRC_MACCJ  (B9EB67    ), PYRC_MARHV  (A1U3L1    ), 
PYRC_METAC  (Q8TSA6    ), PYRC_METFK  (Q1GYZ0    ), PYRC_METJA  (Q58885    ), 
PYRC_METMA  (Q8PVF4    ), PYRC_METTH  (O27199    ), PYRC_MICAN  (B0JQJ1    ), 
PYRC_NEIG1  (Q5F9Y1    ), PYRC_NEIG2  (B4RJT2    ), PYRC_NEIM0  (A9M2W6    ), 
PYRC_NEIMA  (Q9JVD6    ), PYRC_NEIMB  (Q9K0D1    ), PYRC_NEIMF  (A1KSU5    ), 
PYRC_NITEC  (Q0AFI1    ), PYRC_NITEU  (Q82WF3    ), PYRC_NITOC  (Q3J872    ), 
PYRC_ORYSJ  (Q0JJD1    ), PYRC_PEDPA  (Q03HB2    ), PYRC_PELCD  (Q3A449    ), 
PYRC_PELPD  (A1AS12    ), PYRC_PELTS  (A5D1A4    ), PYRC_PEPD6  (Q18C47    ), 
PYRC_PHOLL  (Q7N5W0    ), PYRC_PHOPR  (Q6LPI7    ), PYRC_PSE14  (Q48F12    ), 
PYRC_PSEA6  (Q15YC5    ), PYRC_PSEA7  (A6V1R9    ), PYRC_PSEA8  (B7UVV3    ), 
PYRC_PSEAB  (Q02QZ8    ), PYRC_PSEAE  (P72170    ), PYRC_PSEE4  (Q1IE05    ), 
PYRC_PSEF5  (Q4K747    ), PYRC_PSEFS  (C3KBZ0    ), PYRC_PSEMY  (A4XS41    ), 
PYRC_PSEP1  (A5VZH8    ), PYRC_PSEPF  (Q3K7J8    ), PYRC_PSEPG  (B0KUE9    ), 
PYRC_PSEPK  (Q88NW7    ), PYRC_PSEPW  (B1J4I2    ), PYRC_PSESM  (Q87XM1    ), 
PYRC_PSEU2  (Q4ZPJ8    ), PYRC_PSEU5  (A4VIU5    ), PYRC_PSYIN  (A1SX20    ), 
PYRC_PYRAB  (Q9UXV6    ), PYRC_PYRFU  (Q8U4A0    ), PYRC_PYRHO  (O57740    ), 
PYRC_RALPJ  (B2UFJ8    ), PYRC_RALSO  (Q8Y249    ), PYRC_RHIE6  (B3Q0A1    ), 
PYRC_RHIEC  (Q2KCZ6    ), PYRC_RHIL3  (Q1MM16    ), PYRC_RHILW  (B5ZNS1    ), 
PYRC_RHIME  (Q92SC7    ), PYRC_RHISN  (C3MF80    ), PYRC_RHOS5  (A4WPB7    ), 
PYRC_ROSDO  (Q163V6    ), PYRC_RUEPO  (Q5LQ43    ), PYRC_RUEST  (Q1GFQ7    ), 
PYRC_SALA4  (B5F944    ), PYRC_SALAR  (A9MH00    ), PYRC_SALCH  (Q57QJ4    ), 
PYRC_SALDC  (B5FL01    ), PYRC_SALEP  (B5QY02    ), PYRC_SALG2  (B5RBD7    ), 
PYRC_SALHS  (B4TET5    ), PYRC_SALNS  (B4T2Z5    ), PYRC_SALPA  (Q5PGW5    ), 
PYRC_SALPB  (A9N5P9    ), PYRC_SALPC  (C0Q845    ), PYRC_SALPK  (B5BBC6    ), 
PYRC_SALSV  (B4TSS5    ), PYRC_SALTI  (Q8Z7L2    ), PYRC_SALTY  (P06204    ), 
PYRC_SHEAM  (A1S9L6    ), PYRC_SHEB2  (B8E4P5    ), PYRC_SHEB5  (A3D7V9    ), 
PYRC_SHEB8  (A6WK08    ), PYRC_SHEB9  (A9L3F5    ), PYRC_SHEDO  (Q12NL3    ), 
PYRC_SHEFN  (Q087W5    ), PYRC_SHEHH  (B0TRS6    ), PYRC_SHELP  (A3QAV2    ), 
PYRC_SHEON  (Q8EB40    ), PYRC_SHEPA  (A8H7J4    ), PYRC_SHEPC  (A4Y9S5    ), 
PYRC_SHEPW  (B8CT15    ), PYRC_SHESA  (A0L0B8    ), PYRC_SHESH  (A8FZC6    ), 
PYRC_SHESM  (Q0HLX7    ), PYRC_SHESR  (Q0HRV9    ), PYRC_SHESW  (A1RGK8    ), 
PYRC_SHEWM  (B1KEK5    ), PYRC_SHIB3  (B2TTK9    ), PYRC_SHIBS  (Q31ZB7    ), 
PYRC_SHIDS  (Q32ES3    ), PYRC_SHIF8  (Q0T5X0    ), PYRC_SHIFL  (Q83RT8    ), 
PYRC_SHISS  (Q3Z354    ), PYRC_SINMW  (A6U5N6    ), PYRC_SOLUE  (Q01V55    ), 
PYRC_SPHAL  (Q1GT81    ), PYRC_STAAC  (Q5HGN1    ), PYRC_STAAM  (P65905    ), 
PYRC_STAAN  (P65906    ), PYRC_STAAR  (Q6GHN4    ), PYRC_STAAS  (Q6GA12    ), 
PYRC_STAAW  (P65907    ), PYRC_STAEQ  (Q5HPZ0    ), PYRC_STAES  (Q8CPJ6    ), 
PYRC_STRP1  (Q9A071    ), PYRC_STRP3  (P0DD64    ), PYRC_STRP6  (Q5XCK2    ), 
PYRC_STRP8  (Q7CNB0    ), PYRC_STRPN  (Q97QN4    ), PYRC_STRPQ  (P0DD65    ), 
PYRC_STRR6  (Q8DPQ5    ), PYRC_STRT1  (Q5LZQ6    ), PYRC_STRT2  (Q5M4C1    ), 
PYRC_SULAC  (O08357    ), PYRC_SULSY  (B2V5I6    ), PYRC_SULTO  (Q970X5    ), 
PYRC_SYNFM  (A0LK22    ), PYRC_SYNP2  (B1XI96    ), PYRC_SYNS9  (Q3AYG9    ), 
PYRC_SYNSC  (Q3AKY8    ), PYRC_SYNY3  (P74438    ), PYRC_TERTT  (C5BNK6    ), 
PYRC_THEAC  (Q9HIM0    ), PYRC_THEAQ  (P96081    ), PYRC_THEMA  (Q9WYH0    ), 
PYRC_THEVO  (Q97C35    ), PYRC_USTMA  (P31301    ), PYRC_VARPS  (C5CMK6    ), 
PYRC_VIBCB  (A7N655    ), PYRC_VIBCH  (Q9KL24    ), PYRC_VIBF1  (Q5E0G4    ), 
PYRC_VIBFM  (B5ETI9    ), PYRC_VIBPA  (Q87J46    ), PYRC_VIBTL  (B7VQP0    ), 
PYRC_VIBVU  (Q8D3T9    ), PYRC_VIBVY  (Q7MFB3    ), PYRC_WOLTR  (Q5GSJ0    ), 
PYRC_WOLWR  (C0R5K8    ), PYRC_YEAST  (P20051    )
» more

UniProtKB/Swiss-Prot
False negative sequences
64 sequences

PYRC_AERPE  (Q9YFI5    ), PYRC_CALBD  (B9MS22    ), PYRC_CALS4  (Q8R9R6    ), 
PYRC_CALS8  (A4XKT2    ), PYRC_CHLTE  (Q8KDK5    ), PYRC_CLOAB  (Q97LN7    ), 
PYRC_CLOBA  (B2UW91    ), PYRC_CLOBB  (B2TNG1    ), PYRC_CLOCE  (B8I770    ), 
PYRC_CLOTH  (A3DE07    ), PYRC_COXBR  (A9NA67    ), PYRC_DEIRA  (Q9RVC3    ), 
PYRC_EDWI9  (C5BA73    ), PYRC_ELUMP  (B2KCN5    ), PYRC_FUSNN  (Q8RG88    ), 
PYRC_HELPG  (B5Z6V2    ), PYRC_KLEP3  (B5XXJ5    ), PYRC_KLEP7  (A6T7D6    ), 
PYRC_LACAC  (Q5FJB8    ), PYRC_LACDA  (Q1G867    ), PYRC_LACDB  (Q047M6    ), 
PYRC_LACF3  (B2GD08    ), PYRC_LACGA  (Q043B0    ), PYRC_LACH4  (A8YVZ5    ), 
PYRC_LACJO  (Q74J32    ), PYRC_LACLE  (P48795    ), PYRC_LACS1  (Q1WVB1    ), 
PYRC_LACSS  (Q38X26    ), PYRC_LEIXX  (Q6AF87    ), PYRC_LYSSC  (B1HQB9    ), 
PYRC_MARMS  (A6VXW9    ), PYRC_METKA  (Q8TXX9    ), PYRC_METST  (Q2NHZ6    ), 
PYRC_MYCBO  (Q7U057    ), PYRC_MYCLE  (Q9CCR4    ), PYRC_MYCTO  (P9WHL2    ), 
PYRC_MYCTU  (P9WHL3    ), PYRC_NOVAD  (Q2G9U3    ), PYRC_PECAS  (Q6D698    ), 
PYRC_PECCP  (C6DKU3    ), PYRC_PYRAE  (Q8ZZC7    ), PYRC_RHOBA  (Q7UNR2    ), 
PYRC_RUBXD  (Q1AVY7    ), PYRC_SCHPO  (Q9UTI0    ), PYRC_SERP5  (A8GD09    ), 
PYRC_STRCO  (Q9KXR3    ), PYRC_SULSO  (Q9UX05    ), PYRC_SYNAS  (Q2LVI3    ), 
PYRC_SYNPX  (Q7U618    ), PYRC_SYNR3  (A5GR03    ), PYRC_THEKO  (Q5JJ91    ), 
PYRC_THEP3  (B0KA35    ), PYRC_THEPX  (B0K2E8    ), PYRC_UNCTG  (B1GYY7    ), 
PYRC_YERE8  (A1JN45    ), PYRC_YERP3  (A7FH16    ), PYRC_YERPA  (Q1C6L6    ), 
PYRC_YERPB  (B2K767    ), PYRC_YERPE  (Q8ZFU4    ), PYRC_YERPG  (A9R7Y6    ), 
PYRC_YERPN  (Q1CI09    ), PYRC_YERPP  (A4TLT2    ), PYRC_YERPS  (Q669K2    ), 
PYRC_YERPY  (B1JHH4    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

PYRC_SERMA  (Q9S3S1    )

		
UniProtKB/Swiss-Prot
False positive sequences
14 sequences

ALLB_BACHD  (Q9KAH8    ), ALLB_DEIGD  (Q1J391    ), ALLB_RUBXD  (Q1AS71    ), 
GROU_DROME  (P16371    ), IGA_NEIGO   (P09790    ), IGSF2_HUMAN (Q93033    ), 
LEVR_BACSU  (P23914    ), SPA11_HUMAN (Q86U17    ), UGPC_CUPNH  (Q0K998    ), 
URE1_HALMA  (Q75ZQ5    ), URE1_NATPD  (Q3IRZ5    ), VPS10_ASPFC (B0YA89    ), 
VPS10_ASPFU (Q4WBM1    ), VPS10_NEOFI (A1DAY6    )
» more

PDB
[Detailed view]
36 PDB

1J79; 1XGE; 1XRF; 1XRT; 2E25; 2EG6; 2EG7; 2EG8; 2Z24; 2Z25; 2Z26; 2Z27; 2Z28; 2Z29; 2Z2A; 2Z2B; 3D6N; 3GRI; 3JZE; 3MJM; 3MPG; 4BJH; 4BY3; 4C6C; 4C6D; 4C6E; 4C6F; 4C6I; 4C6J; 4C6K; 4C6L; 4C6M; 4C6N; 4C6O; 4C6P; 4C6Q
» more

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View entry in raw text format (no links)
Direct ScanProsite submission