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Entry: PS00497
General information about the entry
Entry nameTYROSINASE_1
Accession numberPS00497
Entry typePATTERN
DateMAY-1991 (CREATED); APR-2006 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00398
Name and characterization of the entry
DescriptionTyrosinase CuA-binding region signature.
PatternH-x(4,5)-F-[LIVMFTP]-x-[FW]-H-R-x(2)-[LVMT]-x(3)-E.
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 67 hits in 59 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 67 hits in 59 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 9
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 31
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 88.16 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 7
  • `Interesting' site in the pattern: 1,copper
  • `Interesting' site in the pattern: 7,copper
  • VERSION: 2
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
HC2C_MEGCR  (P81732), HCY2A_RAPVE (P80960), HCY2E_RAPVE (P83040), 
HCYA_ENTDO  (P12659), HCYB_HELPO  (P12031), HCYC_SEPOF  (P56824), 
HCYE_SEPOF  (P56825), HCYG_ENTDO  (O61363), HCYG_HELPO  (P56823), 
HCYG_SEPOF  (P56826), PPO1_AGABI  (Q00024), PPO1_IPOBA  (Q9ZP19), 
PPO2_IPOBA  (Q9MB14), PPOA_SOLLC  (Q08303), PPOB_SOLLC  (Q08304), 
PPOB_SOLTU  (Q06355), PPOC_SOLLC  (Q08305), PPOD_SOLLC  (Q08306), 
PPOE_SOLLC  (Q08307), PPOF_SOLLC  (Q08296), PPO_MALDO   (P43309), 
PPO_SPIOL   (P43310), PPO_VICFA   (Q06215), PPO_VITVI   (P43311), 
TYR1_CAEEL  (P34269), TYR3_CAEEL  (Q19673), TYRO_AGABI  (O42713), 
TYRO_ASPFU  (Q8J130), TYRO_ASPOR  (Q00234), TYRO_BOVIN  (Q8MIU0), 
TYRO_CANFA  (P54834), TYRO_CHICK  (P55024), TYRO_COTJA  (Q08410), 
TYRO_GORGO  (Q9BDE0), TYRO_HUMAN  (P14679), TYRO_MOUSE  (P11344), 
TYRO_NEUCR  (P00440), TYRO_ORYLA  (P55025), TYRO_PELNI  (Q04604), 
TYRO_PELSI  (P55026), TYRO_PHONA  (A7BHQ9), TYRO_PINMA  (P86952), 
TYRO_PODAS  (Q92396), TYRO_RHIML  (P33180), TYRO_STRAT  (P07524), 
TYRO_STRGA  (P06845), TYRO_STRGB  (P55022), TYRO_STRLN  (P55023), 
TYRP1_AMBME (P55027), TYRP1_BOVIN (Q8WN57), TYRP1_CARAU (P55028), 
TYRP1_CHICK (O57405), TYRP1_HUMAN (P17643), TYRP1_MOUSE (P07147), 
TYRP2_BOVIN (Q95119), TYRP2_CHICK (O93505), TYRP2_HUMAN (P40126), 
TYRP2_MOUSE (P29812), TYRP2_PIG   (Q4R1H1)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
PHCY1_HOMAM (Q6KF82), PHCY2_HOMAM (Q6KF81), PRP1_BOMMO  (Q27451), 
PRP1_MANSE  (O44249), PRP2_BOMMO  (Q27452), PRP2_MANSE  (Q25519), 
PRPA3_DROME (Q9V521), PRPD3_DROER (Q8I1F6), PRPD3_DROME (Q9W1V6)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
HCY1_HOMAM  (P82296), HCY1_LIODE  (P84461), HCY1_MAISQ  (P82302), 
HCY1_NECPU  (P84846), HCY2_HOMAM  (P82297), HCY2_LIODE  (P84462), 
HCY2_MAISQ  (P82303), HCY2_PANJA  (P82312), HCY3_HOMAM  (P82298), 
HCY3_MAISQ  (P82304), HCY3_PANJA  (P82313), HCY4E_MAISQ (P82306), 
HCY4_CARMA  (P82309), HCY4_HOMAM  (P82299), HCY4_MAISQ  (P82305), 
HCY5_HOMAM  (P82300), HCY5_MAISQ  (P82307), HCY6_HOMAM  (P82301), 
HCY6_MAISQ  (P82308), HCYA_CONCC  (P84619), HCYB_CONCC  (P84620), 
HCYIA_PANJA (P82310), HCYIB_PANJA (P82311), LEC_LITSE   (P84821), 
PHCY_LIODE  (P84460), PHCY_LIOHO  (P84768), PHCY_LIOMA  (P84769), 
PHCY_NECPU  (P84847), PPO_ZINOF   (P85026), PRP1_SIMDA  (P85046), 
TYRO_FELCA  (P55033)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		1BT1; 1BT2; 1BT3; 1BUG; 1JS8; 1LNL; 2P3X;

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