Entry: PS00501

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General information about the entry

Entry name [info] SPASE_I_1
Accession [info] PS00501
Entry type [info] PATTERN
Date [info] MAY-1991 (CREATED); DEC-2004 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00418
Associated ProRule [info] PRU10097

Name and characterization of the entry

Description [info] Signal peptidases I serine active site.
Pattern [info]
[GS]-{PR}-S-M-{RS}-[PS]-[AT]-[LF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 183 in 183 different sequences
Number of true positive hits 121 in 121 different sequences
Number of 'unknown' hits
Number of false positive hits 62 in 62 different sequences
Number of false negative sequences 21
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 66.12 %
Recall (true positives / (true positives + false negatives)) 85.21 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
121 sequences

IMP1_YEAST  (P28627), IMP2_YEAST  (P46972), LEP1_BACAM  (P41026), 
LEP1_SYNY3  (P72660), LEP2_BACAM  (P41025), LEP2_SYNY3  (P73157), 
LEPP_BACNA  (P37943), LEPQ_BACNA  (Q57350), LEPS_BACSU  (P28628), 
LEPT_BACSU  (P71013), LEPU_BACSU  (P42959), LEPV_BACSU  (O07560), 
LEP_AQUAE   (O67088), LEP_BACCL   (P41027), LEP_BACLI   (P42668), 
LEP_BUCAI   (P57347), LEP_BUCAP   (Q8K9R0), LEP_BUCBP   (Q89AM6), 
LEP_ECOLI   (P00803), LEP_HAEIN   (P44454), LEP_MYCLE   (O33021), 
LEP_MYCTO   (P9WKA0), LEP_MYCTU   (P9WKA1), LEP_PHOLA   (Q51876), 
LEP_PSEAE   (Q9I5G7), LEP_PSEFL   (P26844), LEP_SALTI   (P0A1W3), 
LEP_SALTY   (P0A1W2), LEP_STAAC   (Q5HHB9), LEP_STAAM   (P0A067), 
LEP_STAAN   (P0A068), LEP_STAAR   (Q6GIC3), LEP_STAAS   (Q6GAW1), 
LEP_STAAU   (P0A070), LEP_STAAW   (P0A069), LEP_STRPN   (O07344), 
LEP_STRR6   (P59662), PLSP1_ARATH (Q8H0W1), SC11A_BOVIN (P67810), 
SC11A_CANFA (P67811), SC11A_HUMAN (P67812), SC11A_MOUSE (Q9R0P6), 
SC11A_PONAB (Q5R9C7), SC11A_RAT   (P42667), SC11B_HUMAN (P0C7V7), 
SC11C_CANFA (P13679), SC11C_HUMAN (Q9BY50), SC11C_MOUSE (Q9D8V7), 
SC11C_PONAB (Q5RC30), SC11C_RAT   (Q9WTR7), SEC11_AJEC8 (F0UDD2), 
SEC11_AJECG (C0NKT8), SEC11_AJECH (C6HB29), SEC11_AJECN (A6QX24), 
SEC11_AJEDR (C5G8L5), SEC11_AJEDS (C5JJG5), SEC11_ARTBC (D4ALL0), 
SEC11_ARTGP (E4V4X0), SEC11_ARTOC (C5FQ45), SEC11_ASHGO (Q759W4), 
SEC11_ASPCL (A1CL29), SEC11_ASPFC (B0XWT3), SEC11_ASPFU (Q4WYF4), 
SEC11_ASPOR (Q2UBW3), SEC11_ASPTN (Q0CQC5), SEC11_CANAL (Q5A869), 
SEC11_CANAW (C4YNJ0), SEC11_CANDC (B9WKT4), SEC11_CANTT (C5M4J6), 
SEC11_CHAGB (Q2H1P3), SEC11_CLAL4 (C4Y3D4), SEC11_COCP7 (C5PA33), 
SEC11_COCPS (E9CXH2), SEC11_COLGM (E3QXY4), SEC11_DEBHA (Q6BP15), 
SEC11_DICDI (Q86JD4), SEC11_EMENI (Q5B8K4), SEC11_GROCL (F0XJH4), 
SEC11_KLULA (Q6CMR5), SEC11_LACBS (B0D4L0), SEC11_LACTC (C5DDH1), 
SEC11_LEPMJ (E5A8D2), SEC11_LODEL (A5DS09), SEC11_MAGO7 (A4RGA1), 
SEC11_METAQ (E9E796), SEC11_METAR (E9F8V9), SEC11_NECH7 (C7ZHK5), 
SEC11_NEOFI (A1D6D8), SEC11_NEUCR (Q7RY44), SEC11_OGAPD (E7R7C4), 
SEC11_PARBA (C1GU90), SEC11_PARBD (C1FYD2), SEC11_PARBP (C0S3S0), 
SEC11_PENCW (B6HC89), SEC11_PENMQ (B6Q5G0), SEC11_PICGU (A5DIZ8), 
SEC11_PICPG (C4QXP7), SEC11_PICST (A3LXS1), SEC11_PODAN (B2B3T2), 
SEC11_PYRTR (B2WEL2), SEC11_PYRTT (E3RR70), SEC11_SCHCM (D8Q7Q5), 
SEC11_SCLS1 (A7E716), SEC11_TALSN (B8M5K5), SEC11_TRIVH (D4D5I1), 
SEC11_TUBMM (D5GNC3), SEC11_UNCRE (C4JYM4), SEC11_VERA1 (C9S8G0), 
SEC11_YEAS1 (B3LTI7), SEC11_YEAS2 (C7GLT4), SEC11_YEAS7 (A6ZVU2), 
SEC11_YEAS8 (C8ZAS4), SEC11_YEASA (E7KDY6), SEC11_YEASB (E7Q587), 
SEC11_YEASL (E7KQ01), SEC11_YEAST (P15367), SEC11_YEASV (E7LVX4), 
SEC11_YEASZ (E7QG89), SEC11_ZYGRC (C5E3W1), TPP1_ARATH  (O04348), 
TPP2_ARATH  (Q9M9Z2)
» More

UniProtKB/Swiss-Prot
False negative sequences
21 sequences

IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39), 
IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4), IMP2L_HUMAN (Q96T52), 
IMP2L_MOUSE (Q8BPT6), IMP2L_SCHPO (Q9UST2), IMP2L_XENLA (Q5PQ63), 
LEPH_STAAC  (Q5HHC0), LEPH_STAAM  (P0A063), LEPH_STAAN  (P0A064), 
LEPH_STAAR  (Q6GIC4), LEPH_STAAS  (Q6GAW2), LEPH_STAAU  (P0A066), 
LEPH_STAAW  (P0A065), LEP_HELPJ   (Q9ZLQ5), LEP_HELPY   (O25300), 
LEP_RICCN   (Q92JB1), LEP_RICPR   (Q9ZE32), SEC11_YARLI (Q6CAG9)
» More

UniProtKB/Swiss-Prot
False positive sequences
62 sequences

ALDO1_ARATH (Q7G193), AQPZ_ECO57  (Q8X6K6), AQPZ_ECOL6  (P60845), 
AQPZ_ECOLI  (P60844), AQPZ_SHIFL  (O68874), ATG12_ASPCL (A1CTJ1), 
ATG12_ASPFU (A4D9P4), ATG12_ASPOR (Q2UMW6), ATG12_COCIM (Q1E8C2), 
ATG12_MAGO7 (Q51P78), ATG12_NEOFI (A1DMW6), CDKL5_HUMAN (O76039), 
DDL_SYNPW   (A5GML7), ERF1_CAEEL  (O16520), FREM1_HUMAN (Q5H8C1), 
GNL3L_BOVIN (Q3T0J9), GNL3L_HUMAN (Q9NVN8), LVSD_DICDI  (Q55AV3), 
L_CHAVB     (B2C4J3), NAGA_HUMAN  (Q9Y303), NFAA_DICDI  (Q55AR6), 
O51S1_HUMAN (Q8NGJ8), PEPF1_LACLC (P54124), PEPF_LACLA  (Q9CEV7), 
PLSX_PARDP  (A1B363), PLSX_RUEST  (Q1GI68), POC1A_MOUSE (Q8JZX3), 
PPE19_MYCTO (P9WI24), PPE19_MYCTU (P9WI25), PR2_DROME   (Q9I7F7), 
RIMB2_MOUSE (Q80U40), RIMB2_RAT   (Q9JIR1), RS9_STRCO   (Q53875), 
SNL4_ARATH  (O04539), SNT2_YEAST  (P53127), STU1_SCHPO  (O42874), 
TBB1_AVESA  (P25862), TBB1_ORYSJ  (Q43594), TBB1_WHEAT  (Q9ZRB2), 
TBB2_ELEIN  (Q9ZPN9), TBB2_WHEAT  (Q9ZRB1), TBB3_GOSHI  (Q6VAF8), 
TBB3_PEA    (P29502), TBB4_ELEIN  (Q9ZPN7), TBB4_ORYSJ  (P45960), 
TBB5_MAIZE  (Q43697), TBB5_WHEAT  (Q9ZRA8), TBB6_ARATH  (P29514), 
TBB6_MAIZE  (Q41783), TBB6_ORYSJ  (Q76FS3), TBB8_MAIZE  (Q41785), 
TBB8_ORYSJ  (Q76FS2), TBB_HORVU   (P93176), TDA7_CANGA  (Q6FNJ6), 
TPIS_GRAGA  (P48492), TPO5_YEAST  (P36029), TRM51_VITVI (F6H2F8), 
UPP3_SCHPO  (Q9US43), VPS10_NECH7 (C7YGZ0), Y017_OSHVF  (Q6R7K6), 
ZF69B_HUMAN (Q9UJL9), ZN598_DANRE (Q6PFK1)
» More

PDB
[Detailed view]
5 PDB

1B12; 1KN9; 1T7D; 3IIQ; 3S04

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