Entry: PS00589

General information about the entry

Entry name [info] PTS_HPR_SER
Accession [info] PS00589
Entry type [info] PATTERN
Date [info] DEC-1991 (CREATED); APR-2006 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00318

Name and characterization of the entry

Description [info] PTS HPR domain serine phosphorylation site signature.
Pattern [info]
[GSTADE]-[KREQSTIV]-x-{EPRK}-{VPGL}-x-[KRDN]-S-[LIVMF](2)-{EVPL}-[LIVM]-
{EATN}-x-[LIVM]-[GADE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 138 in 137 different sequences
Number of true positive hits 77 in 76 different sequences
Number of 'unknown' hits 0
Number of false positive hits 61 in 61 different sequences
Number of false negative sequences 7
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 55.80 %
Recall (true positives / (true positives + false negatives)) 91.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] phosphorylation at position 8
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
76 sequences

ACRB_ASPCL  (A1CIK0), ACRB_ASPFC  (B0Y4N5), ACRB_ASPFU  (Q4WQG9), 
ACRB_ASPNC  (A2Q9L8), ACRB_ASPOR  (Q2UUI0), ACRB_ASPTN  (Q0CT23), 
ACRB_EMENI  (Q876Q0), ACRB_NEOFI  (A1CW63), CRH_BACHD   (Q9K708), 
CRH_BACSU   (O06976), PTFAH_ECO57 (P69812), PTFAH_ECOLI (P69811), 
PTFAH_HAEIN (P44715), PTFAH_SALTI (Q8Z591), PTFAH_SALTY (P17127), 
PTFAX_RHOCA (P23388), PTFAX_XANCP (P45597), PTHP_BACHD  (Q9K8D2), 
PTHP_BACME  (O69250), PTHP_BACSU  (P08877), PTHP_BACTI  (Q9F166), 
PTHP_BORBU  (O51507), PTHP_BUCAI  (Q9WXI5), PTHP_BUCAP  (Q8KA49), 
PTHP_BUCBP  (Q89B03), PTHP_CHLMU  (Q9PK56), PTHP_CHLPN  (Q9Z9E4), 
PTHP_CHLTR  (O84341), PTHP_CUPNH  (P23537), PTHP_ECO57  (P0AA06), 
PTHP_ECOL6  (P0AA05), PTHP_ECOLI  (P0AA04), PTHP_ENTFA  (P07515), 
PTHP_GEOSE  (P42013), PTHP_HAEIN  (P43921), PTHP_KLEPN  (P16481), 
PTHP_LACCA  (Q9KJV3), PTHP_LACLA  (Q9CJ83), PTHP_LACLC  (Q9ZAD9), 
PTHP_LACSK  (O07125), PTHP_LISIN  (P0A439), PTHP_LISMO  (P0A438), 
PTHP_LYSSH  (Q84F84), PTHP_MYCCT  (P45611), PTHP_MYCGE  (P47287), 
PTHP_MYCPN  (P75061), PTHP_NEIMA  (P65876), PTHP_NEIMB  (P65877), 
PTHP_PSEAE  (Q9HVV2), PTHP_PSEPU  (Q9Z426), PTHP_SALTI  (P0AA08), 
PTHP_SALTY  (P0AA07), PTHP_SHIFL  (P0AA09), PTHP_STAAC  (Q5HH02), 
PTHP_STAAM  (P0A0E1), PTHP_STAAN  (P99143), PTHP_STAAR  (Q6GI02), 
PTHP_STAAS  (Q6GAD1), PTHP_STAAU  (P0A0E3), PTHP_STAAW  (P0A0E2), 
PTHP_STACA  (P23534), PTHP_STAXY  (Q9EYQ9), PTHP_STREI  (Q9WXK8), 
PTHP_STRMU  (P45596), PTHP_STRSL  (P24366), PTHP_TREPA  (O83598), 
PTHP_VIBCH  (Q9KTD6), PTHP_XYLFA  (Q9PDH6), PTHP_XYLFT  (Q87DQ0), 
PTSO_ECO57  (P0A9N2), PTSO_ECOL6  (P0A9N1), PTSO_ECOLI  (P0A9N0), 
PTSO_KLEOX  (P51185), PTSO_PROMH  (Q9ZA86), PTSO_SHIFL  (P0A9N3), 
PTSO_VIBCH  (Q9KP46)
» More

UniProtKB/Swiss-Prot
False negative sequences
7 sequences

DHAM_ECOLI  (P37349), PTFAX_ECO57 (Q8XBQ8), PTFAX_ECOL6 (Q8FFD8), 
PTFAX_SHIFL (Q83QP3), PTFX1_ECOLI (P77439), PTFX2_ECOLI (P32670), 
PTSO_SHEVD  (Q9S0K8)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

PTHP_STRSA  (P24365)

		
UniProtKB/Swiss-Prot
False positive sequences
61 sequences

206L_IIV6   (Q91FW4), AB39G_ARATH (Q7PC84), AB5F_ARATH  (Q9LV93), 
ABTB1_MOUSE (Q99LJ2), ABTB1_RAT   (Q5XIU1), AMPM_HELVI  (Q11000), 
ATX2_YEAST  (Q12067), DGGGP_SULAC (Q4J8K2), DNLJ_MYCGA  (Q7NAF8), 
FAP1_ARATH  (Q9M1X2), FOXF_DROME  (Q9VS05), GPPA_PSEA6  (Q15N19), 
HNMT_XENTR  (Q0V9P1), ILVD_PROMT  (Q46LF6), IQG1_CANAL  (Q5AH02), 
LRCH1_HUMAN (Q9Y2L9), MABP1_HUMAN (O60336), MABP1_MOUSE (Q6NS57), 
MASZ1_PSESM (Q88AB2), MASZ_ECOL6  (Q8FDN6), MASZ_ECOLI  (P37330), 
MASZ_PSEFL  (O05137), MASZ_PSEPK  (Q88QX8), MASZ_SHIFL  (P59663), 
MHPA1_BURVG (A4JPY1), MHPA_BURXL  (Q13QI0), MHPA_COMTE  (Q9S158), 
MHPA_CUPPJ  (Q476N1), NRG1_RAT    (P43322), OR83A_DROME (Q9VNB3), 
PHYB1_SOLLC (Q9ZS62), PKS5_DICDI  (Q86JI5), PPA14_ARATH (Q84LR6), 
PPA29_ARATH (Q9FMK9), PRIS_HALMA  (Q5V554), RBGA_BACCR  (Q819W8), 
RBGA_BACLD  (Q65JP4), RK14_BIGNA  (Q06J57), RL14_BDEBA  (Q6MJ24), 
RPOC2_PROM1 (A2C4N0), RPOC2_PROMT (Q46J24), RS1_BUCBP   (Q89AJ3), 
RS5_RHOBA   (Q7UN03), SATC_AQUAE  (O67174), SSTT_DESHY  (Q24XD0), 
SYC_TREDE   (Q73RJ6), TEX2_HUMAN  (Q8IWB9), TEX2_MOUSE  (Q6ZPJ0), 
TM41B_HUMAN (Q5BJD5), TM41B_PONAB (Q5RBZ8), TM41B_RAT   (Q5FVN2), 
TM41B_XENLA (Q5U4K5), TM41B_XENTR (A4II98), TP53B_MOUSE (P70399), 
TRM5_ENCCU  (Q8SVV3), TRPG_CRYNB  (P0CN87), TRPG_CRYNH  (P27710), 
TRPG_CRYNJ  (P0CN86), VPS25_DANRE (Q6NWF4), Y389_CHLPN  (Q9Z8F4), 
YCF2_PSINU  (Q8WHW9)
» More

PDB
[Detailed view]
32 PDB

1CM2; 1CM3; 1GGR; 1HDN; 1J6T; 1JEM; 1K1C; 1KA5; 1KKL; 1MU4; 1PCH; 1PFH; 1POH; 1PTF; 1QFR; 1QR5; 1TXE; 1VRC; 1Y4Y; 1Y50; 1Y51; 2HID; 2HPR; 2JEL; 2LRK; 2LRL; 2RLZ; 2XDF; 3CCD; 3EZA; 3EZB; 3EZE
» More

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