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Entry: PS00589

General information about the entry

Entry name [info] PTS_HPR_SER
Accession [info] PS00589
Entry type [info] PATTERN
Date [info] 01-DEC-1991 CREATED; 01-APR-2006 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00318

Name and characterization of the entry

Description [info] PTS HPR domain serine phosphorylation site signature.
Pattern [info]
[GSTADE]-[KREQSTIV]-x-{EPRK}-{VPGL}-x-[KRDN]-S-[LIVMF](2)-{EVPL}-[LIVM]-
{EATN}-x-[LIVM]-[GADE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 138 in 137 different sequences
Number of true positive hits 77 in 76 different sequences
Number of 'unknown' hits 0
Number of false positive hits 61 in 61 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 55.80 %
Recall (true positives / (true positives + false negatives)) 88.51 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] phosphorylation at position 8
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
76 sequences

ACRB_ASPCL  (A1CIK0    ), ACRB_ASPFC  (B0Y4N5    ), ACRB_ASPFU  (Q4WQG9    ), 
ACRB_ASPNC  (A2Q9L8    ), ACRB_ASPOR  (Q2UUI0    ), ACRB_ASPTN  (Q0CT23    ), 
ACRB_EMENI  (Q876Q0    ), ACRB_NEOFI  (A1CW63    ), CRH_BACHD   (Q9K708    ), 
CRH_BACSU   (O06976    ), PTFAH_ECO57 (P69812    ), PTFAH_ECOLI (P69811    ), 
PTFAH_HAEIN (P44715    ), PTFAH_SALTI (Q8Z591    ), PTFAH_SALTY (P17127    ), 
PTFAX_RHOCA (P23388    ), PTFAX_XANCP (P45597    ), PTHP_BACHD  (Q9K8D2    ), 
PTHP_BACME  (O69250    ), PTHP_BACSU  (P08877    ), PTHP_BACTI  (Q9F166    ), 
PTHP_BORBU  (O51507    ), PTHP_BUCAI  (Q9WXI5    ), PTHP_BUCAP  (Q8KA49    ), 
PTHP_BUCBP  (Q89B03    ), PTHP_CHLMU  (Q9PK56    ), PTHP_CHLPN  (Q9Z9E4    ), 
PTHP_CHLTR  (O84341    ), PTHP_CUPNH  (P23537    ), PTHP_ECO57  (P0AA06    ), 
PTHP_ECOL6  (P0AA05    ), PTHP_ECOLI  (P0AA04    ), PTHP_ENTFA  (P07515    ), 
PTHP_GEOSE  (P42013    ), PTHP_HAEIN  (P43921    ), PTHP_KLEPN  (P16481    ), 
PTHP_LACCA  (Q9KJV3    ), PTHP_LACLA  (Q9CJ83    ), PTHP_LACLC  (Q9ZAD9    ), 
PTHP_LACSK  (O07125    ), PTHP_LISIN  (P0A439    ), PTHP_LISMO  (P0A438    ), 
PTHP_LYSSH  (Q84F84    ), PTHP_MYCCT  (P45611    ), PTHP_MYCGE  (P47287    ), 
PTHP_MYCPN  (P75061    ), PTHP_NEIMA  (P65876    ), PTHP_NEIMB  (P65877    ), 
PTHP_PSEAE  (Q9HVV2    ), PTHP_PSEPU  (Q9Z426    ), PTHP_SALTI  (P0AA08    ), 
PTHP_SALTY  (P0AA07    ), PTHP_SHIFL  (P0AA09    ), PTHP_STAAC  (Q5HH02    ), 
PTHP_STAAM  (P0A0E1    ), PTHP_STAAN  (P99143    ), PTHP_STAAR  (Q6GI02    ), 
PTHP_STAAS  (Q6GAD1    ), PTHP_STAAU  (P0A0E3    ), PTHP_STAAW  (P0A0E2    ), 
PTHP_STACA  (P23534    ), PTHP_STAXY  (Q9EYQ9    ), PTHP_STREI  (Q9WXK8    ), 
PTHP_STRMU  (P45596    ), PTHP_STRSL  (P24366    ), PTHP_TREPA  (O83598    ), 
PTHP_VIBCH  (Q9KTD6    ), PTHP_XYLFA  (Q9PDH6    ), PTHP_XYLFT  (Q87DQ0    ), 
PTSO_ECO57  (P0A9N2    ), PTSO_ECOL6  (P0A9N1    ), PTSO_ECOLI  (P0A9N0    ), 
PTSO_KLEOX  (P51185    ), PTSO_PROMH  (Q9ZA86    ), PTSO_SHIFL  (P0A9N3    ), 
PTSO_VIBCH  (Q9KP46    )
» more

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

DHAM_ECOLI  (P37349    ), DHAM_KLEOK  (A0A0H3H456), DHAM_PANAM  (D4GL26    ), 
DHAM_PROSM  (P0DN88    ), PTFX1_ECOLI (P77439    ), PTFX2_ECOLI (P32670    ), 
PTFX_ECO57  (Q8XBQ8    ), PTFX_ECOL6  (Q8FFD8    ), PTFX_SHIFL  (Q83QP3    ), 
PTSO_SHEVD  (Q9S0K8    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

PTHP_STRSA  (P24365    )

		
UniProtKB/Swiss-Prot
False positive sequences
61 sequences

206L_IIV6   (Q91FW4    ), AB39G_ARATH (Q7PC84    ), AB5F_ARATH  (Q9LV93    ), 
ABTB1_MOUSE (Q99LJ2    ), ABTB1_RAT   (Q5XIU1    ), AMPM_HELVI  (Q11000    ), 
ATX2_YEAST  (Q12067    ), DGGGP_SULAC (Q4J8K2    ), DNLJ_MYCGA  (Q7NAF8    ), 
FAP1_ARATH  (Q9M1X2    ), FOXF_DROME  (Q9VS05    ), GPPA_PSEA6  (Q15N19    ), 
HNMT_XENTR  (Q0V9P1    ), ILVD_PROMT  (Q46LF6    ), IQG1_CANAL  (Q5AH02    ), 
LRCH1_HUMAN (Q9Y2L9    ), MABP1_HUMAN (O60336    ), MABP1_MOUSE (Q6NS57    ), 
MASZ1_PSESM (Q88AB2    ), MASZ_ECOL6  (Q8FDN6    ), MASZ_ECOLI  (P37330    ), 
MASZ_PSEFL  (O05137    ), MASZ_PSEPK  (Q88QX8    ), MASZ_SHIFL  (P59663    ), 
MHPA1_BURVG (A4JPY1    ), MHPA_COMTE  (Q9S158    ), MHPA_CUPNJ  (Q476N1    ), 
MHPA_PARXL  (Q13QI0    ), NRG1_RAT    (P43322    ), OR83A_DROME (Q9VNB3    ), 
PHYB1_SOLLC (Q9ZS62    ), PKS5_DICDI  (Q86JI5    ), PPA14_ARATH (Q84LR6    ), 
PPA29_ARATH (Q9FMK9    ), PRIS_HALMA  (Q5V554    ), RBGA_BACCR  (Q819W8    ), 
RBGA_BACLD  (Q65JP4    ), RK14_BIGNA  (Q06J57    ), RL14_BDEBA  (Q6MJ24    ), 
RPOC2_PROM1 (A2C4N0    ), RPOC2_PROMT (Q46J24    ), RS1_BUCBP   (Q89AJ3    ), 
RS5_RHOBA   (Q7UN03    ), SATC_AQUAE  (O67174    ), SSTT_DESHY  (Q24XD0    ), 
SYC_TREDE   (Q73RJ6    ), TEX2_HUMAN  (Q8IWB9    ), TEX2_MOUSE  (Q6ZPJ0    ), 
TM41B_HUMAN (Q5BJD5    ), TM41B_PONAB (Q5RBZ8    ), TM41B_RAT   (Q5FVN2    ), 
TM41B_XENLA (Q5U4K5    ), TM41B_XENTR (A4II98    ), TP53B_MOUSE (P70399    ), 
TRM5_ENCCU  (Q8SVV3    ), TRPG_CRYNB  (P0CN87    ), TRPG_CRYNH  (P27710    ), 
TRPG_CRYNJ  (P0CN86    ), VPS25_DANRE (Q6NWF4    ), Y389_CHLPN  (Q9Z8F4    ), 
YCF2_PSINU  (Q8WHW9    )
» more

PDB
[Detailed view]
34 PDB

1CM2; 1CM3; 1GGR; 1HDN; 1J6T; 1JEM; 1K1C; 1KA5; 1KKL; 1MU4; 1PCH; 1PFH; 1POH; 1PTF; 1QFR; 1QR5; 1TXE; 1VRC; 1Y4Y; 1Y50; 1Y51; 2HID; 2HPR; 2JEL; 2LRK; 2LRL; 2RLZ; 2XDF; 3CCD; 3EZA; 3EZB; 3EZE; 4XWJ; 5T17
» more

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