Entry: PS00633

General information about the entry

Entry name [info] BROMODOMAIN_1
Accession [info] PS00633
Entry type [info] PATTERN
Date [info] JUN-1992 (CREATED); DEC-2004 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00550

Name and characterization of the entry

Description [info] Bromodomain signature.
Pattern [info]
[STANVFHG]-x(2)-[FAS]-x(4)-[DNSPAKT]-x(0,7)-[DENQTFG]-Y-[HFYLRKT]-x(2)-
[LIVMFY]-x(3)-[LIVM]-x(4)-[LIVM]-x(6,10)-Y-x(12,13)-[LIVM]-x(2)-N-[SACF]-
x(2)-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 139 in 106 different sequences
Number of true positive hits 139 in 106 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 52
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 72.77 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
106 sequences

ATD2B_HUMAN (Q9ULI0    ), BAZ1A_HUMAN (Q9NRL2    ), BAZ1A_MOUSE (O88379    ), 
BAZ1A_XENLA (Q8UVR5    ), BAZ1B_HUMAN (Q9UIG0    ), BAZ1B_MOUSE (Q9Z277    ), 
BAZ2A_HUMAN (Q9UIF9    ), BAZ2A_MOUSE (Q91YE5    ), BAZ2A_XENLA (B7ZS37    ), 
BAZ2B_CHICK (Q9DE13    ), BAZ2B_HUMAN (Q9UIF8    ), BDF1_CANAL  (Q5A4W8    ), 
BDF1_SCHPO  (Q9Y7N0    ), BDF1_YEAST  (P35817    ), BDF2_YEAST  (Q07442    ), 
BET1_CAEEL  (Q95Y80    ), BPTF_HUMAN  (Q12830    ), BRD1_HUMAN  (O95696    ), 
BRD2_BOVIN  (Q32S26    ), BRD2_CANLF  (Q5TJG6    ), BRD2_HUMAN  (P25440    ), 
BRD2_MOUSE  (Q7JJ13    ), BRD2_RAT    (Q6MGA9    ), BRD3_HUMAN  (Q15059    ), 
BRD3_MOUSE  (Q8K2F0    ), BRD4A_XENLA (Q08D75    ), BRD4B_XENLA (Q6DFF2    ), 
BRD4_DANRE  (F1R5H6    ), BRD4_HUMAN  (O60885    ), BRD4_MOUSE  (Q9ESU6    ), 
BRD9_XENLA  (Q6GLP7    ), BRD9_XENTR  (Q6NVM8    ), BRDT_DANRE  (F1QW93    ), 
BRDT_HUMAN  (Q58F21    ), BRDT_MACFA  (Q4R8Y1    ), BRDT_MOUSE  (Q91Y44    ), 
BRDT_RAT    (D4A7T3    ), BRDT_XENTR  (F7DRV9    ), BRM_DROME   (P25439    ), 
BRPF1_HUMAN (P55201    ), BRPF3_HUMAN (Q9ULD4    ), BRWD1_HUMAN (Q9NSI6    ), 
BRWD1_MOUSE (Q921C3    ), CBP1_CAEEL  (P34545    ), CBP_HUMAN   (Q92793    ), 
CBP_MOUSE   (P45481    ), CBP_RAT     (Q6JHU9    ), CECR2_HUMAN (Q9BXF3    ), 
EP300_HUMAN (Q09472    ), EP300_MOUSE (B2RWS6    ), FSH_DROME   (P13709    ), 
GCN5_ARATH  (Q9AR19    ), GCN5_ASHGO  (Q756G9    ), GCN5_CANGA  (Q6FTW5    ), 
GCN5_DEBHA  (Q6BGW1    ), GCN5_KLULA  (Q6CXW4    ), GCN5_ORYSJ  (Q338B9    ), 
GCN5_SCHPO  (Q9UUK2    ), GCN5_YARLI  (Q8WZM0    ), GCN5_YEAST  (Q03330    ), 
GTE1_ARATH  (Q84XV2    ), KAT2A_HUMAN (Q92830    ), KAT2A_MOUSE (Q9JHD2    ), 
KAT2B_HUMAN (Q92831    ), KAT2B_MOUSE (Q9JHD1    ), LIN49_CAEEL (Q20318    ), 
NU301_DROME (Q9W0T1    ), PB1_CHICK   (Q90941    ), PB1_HUMAN   (Q86U86    ), 
PB1_MOUSE   (Q8BSQ9    ), PHIP_HUMAN  (Q8WWQ0    ), PHIP_MOUSE  (Q8VDD9    ), 
RSC1_SCHPO  (O74964    ), RSC1_YEAST  (P53236    ), RSC2_YEAST  (Q06488    ), 
RSC4_YEAST  (Q02206    ), SMCA2_HUMAN (P51531    ), SMCA2_MOUSE (Q6DIC0    ), 
SMCA4_BOVIN (A7Z019    ), SMCA4_HUMAN (P51532    ), SMCA4_MOUSE (Q3TKT4    ), 
SMCA4_RAT   (Q8K1P7    ), SNF21_SCHPO (Q9UTN6    ), SNF22_SCHPO (O94421    ), 
SNF2_YEAST  (P22082    ), SPT7_SCHPO  (P87152    ), SPT7_YEAST  (P35177    ), 
STH1_YEAST  (P32597    ), TAF1B_ARATH (Q6PUA2    ), TAF1L_HUMAN (Q8IZX4    ), 
TAF1_ARATH  (Q8LRK9    ), TAF1_CAEEL  (G5EGM3    ), TAF1_DICDI  (Q54DH8    ), 
TAF1_DROME  (P51123    ), TAF1_HUMAN  (P21675    ), TAF1_MESAU  (Q60544    ), 
TAF1_MOUSE  (Q80UV9    ), TAF1_ORYSJ  (Q67W65    ), TBP7_CAEBR  (A8X0L9    ), 
TBP7_CAEEL  (P54816    ), TIF1A_HUMAN (O15164    ), TIF1A_MOUSE (Q64127    ), 
Y0170_DICDI (Q55C84    ), Y1591_ARATH (F4IAE9    ), Y3800_DICDI (Q54BA2    ), 
YK82_SCHPO  (Q9HGP4    )
» more

UniProtKB/Swiss-Prot
False negative sequences
52 sequences

ASH1L_HUMAN (Q9NR48    ), ASH1L_MOUSE (Q99MY8    ), ATAD2_HUMAN (Q6PL18    ), 
ATAD2_MOUSE (Q8CDM1    ), BAZ1B_DANRE (A2BIL7    ), BAZ1B_XENLA (A8DZJ1    ), 
BDC1_SCHPO  (O74350    ), BRD7_CHICK  (Q5ZKG2    ), BRD7_HUMAN  (Q9NPI1    ), 
BRD7_MOUSE  (O88665    ), BRD7_PONAB  (Q5R8B0    ), BRD8_HUMAN  (Q9H0E9    ), 
BRD8_MOUSE  (Q8R3B7    ), BRD9_DANRE  (Q7ZUF2    ), BRD9_HUMAN  (Q9H8M2    ), 
BRD9_MOUSE  (Q3UQU0    ), BRM_ARATH   (Q6EVK6    ), BRWD3_HUMAN (Q6RI45    ), 
BRWD3_MOUSE (A2AHJ4    ), GTE10_ARATH (Q9FGW9    ), GTE11_ARATH (Q93ZB7    ), 
GTE12_ARATH (Q9LS28    ), GTE2_ARATH  (Q9LXA7    ), GTE3_ARATH  (Q9S7T1    ), 
GTE4_ARATH  (Q9LNC4    ), GTE5_ARATH  (Q8H1D7    ), GTE6_ARATH  (Q9FT54    ), 
GTE7_ARATH  (Q7Y214    ), GTE8_ARATH  (Q9LK27    ), GTE9_ARATH  (Q93YS6    ), 
KMT2A_MOUSE (P55200    ), MBD9_ARATH  (Q9SGH2    ), NU301_CAEEL (Q6BER5    ), 
RSC4_SCHPO  (Q09948    ), SET1_PLAF7  (C6KTD2    ), SP110_HUMAN (Q9HB58    ), 
SP140_HUMAN (Q13342    ), SP14L_HUMAN (Q9H930    ), TBP7_YEAST  (P40340    ), 
TIF1B_HUMAN (Q13263    ), TIF1B_MOUSE (Q62318    ), TIF1B_RAT   (O08629    ), 
TRI33_DANRE (Q6E2N3    ), TRI33_HUMAN (Q9UPN9    ), TRI33_XENLA (Q56R14    ), 
TRI66_HUMAN (O15016    ), TRI66_MOUSE (Q924W6    ), Y0777_DICDI (Q54UW4    ), 
Y1118_DICDI (Q55BK3    ), Y5837_DICDI (Q54MP8    ), Y7958_DICDI (Q55FT8    ), 
Y8469_DICDI (Q54Y18    )
» more

PDB
[Detailed view]
414 PDB

1E6I; 1EQF; 1F68; 1JM4; 1JSP; 1N72; 1WUG; 1WUM; 1ZS5; 2D82; 2D9E; 2DAT; 2DKW; 2DVV; 2E3K; 2E7N; 2E7O; 2G4A; 2GRC; 2H60; 2KTB; 2L5E; 2L84; 2L85; 2NXB; 2OO1; 2OSS; 2R0V; 2R10; 2RFJ; 2RI7; 2RNW; 2RNX; 2RNY; 2RS9; 2WP1; 2WP2; 2YDW; 2YEK; 2YEL; 2YQD; 2YW5; 2YYN; 3AAD; 3D7C; 3DWY; 3G0J; 3G0L; 3GG3; 3HMF; 3HMH; 3I3J; 3IU5; 3JVJ; 3JVK; 3K2J; 3LJW; 3LXJ; 3MB3; 3MB4; 3MUK; 3MUL; 3MXF; 3NXB; 3O33; 3O34; 3O35; 3O36; 3O37; 3ONI; 3P1C; 3P1D; 3P1E; 3P1F; 3P5O; 3Q2E; 3Q2F; 3QZS; 3QZT; 3QZV; 3RCW; 3S91; 3S92; 3SVF; 3SVG; 3SVH; 3TLP; 3U5J; 3U5K; 3U5L; 3UV2; 3UV4; 3UV5; 3UVD; 3UVW; 3UVX; 3UVY; 3UW9; 3ZYU; 4A9E; 4A9F; 4A9H; 4A9I; 4A9J; 4A9K; 4A9L; 4A9M; 4A9N; 4A9O; 4AKN; 4ALG; 4ALH; 4BHW; 4BJX; 4BW1; 4BW2; 4BW3; 4BW4; 4C66; 4C67; 4CFK; 4CFL; 4CL9; 4CLB; 4CUP; 4CUQ; 4CUR; 4CUS; 4CUT; 4CUU; 4DON; 4E96; 4F3I; 4FLP; 4GPJ; 4HBV; 4HBW; 4HBX; 4HBY; 4HXK; 4HXL; 4HXM; 4HXN; 4HXO; 4HXP; 4HXR; 4HXS; 4IOO; 4IOQ; 4IOR; 4IR3; 4IR4; 4IR5; 4IR6; 4J0R; 4J0S; 4J1P; 4J3I; 4KCX; 4KV1; 4LC2; 4LR6; 4LRG; 4LYI; 4LYS; 4LYW; 4LZ2; 4LZR; 4LZS; 4MEN; 4MEO; 4MEP; 4MEQ; 4MR3; 4MR4; 4MR5; 4MR6; 4N3W; 4N4F; 4NQM; 4NR4; 4NR5; 4NR6; 4NR7; 4NR8; 4NR9; 4NRA; 4NRB; 4NRC; 4NUC; 4NUD; 4NUE; 4NYV; 4NYW; 4NYX; 4O70; 4O71; 4O72; 4O74; 4O75; 4O76; 4O77; 4O78; 4O7A; 4O7B; 4O7C; 4O7E; 4O7F; 4OGI; 4OGJ; 4OUF; 4PCE; 4PCI; 4PS5; 4Q0N; 4Q0O; 4QB3; 4QBM; 4QC1; 4QC3; 4QEU; 4QEV; 4QEW; 4QR3; 4QR4; 4QR5; 4QY4; 4QYD; 4QYL; 4RVR; 4TQN; 4TS8; 4UIX; 4UIY; 4UIZ; 4UYD; 4UYE; 4UYF; 4UYG; 4UYH; 4WHU; 4WHW; 4WIV; 4X2I; 4XUA; 4XUB; 4XY9; 4XYA; 4Y03; 4YAB; 4YAD; 4YAT; 4YAX; 4YBM; 4YBS; 4YBT; 4YC9; 4YH3; 4YH4; 4YK0; 4YYM; 4YYN; 4Z1Q; 4Z1S; 4ZC9; 4ZQL; 4ZW1; 5A5S; 5A7C; 5A85; 5ACY; 5AD2; 5AD3; 5AME; 5AMF; 5BT3; 5BT4; 5BT5; 5C7N; 5C85; 5C87; 5C89; 5CFW; 5CGP; 5COI; 5CP5; 5CPE; 5CQ3; 5CQ4; 5CQ5; 5CQ6; 5CQ7; 5CQ8; 5CQA; 5CQT; 5CRM; 5CRZ; 5CS8; 5CTL; 5CU8; 5CUA; 5CUB; 5CUC; 5CUD; 5CUE; 5CUG; 5CY9; 5D0C; 5D24; 5D25; 5D26; 5D3H; 5D3J; 5D3L; 5D3N; 5D3P; 5D3R; 5D3S; 5D3T; 5D7X; 5DBM; 5DFB; 5DFC; 5DFD; 5DKC; 5DKD; 5DKH; 5DLX; 5DLZ; 5DW1; 5DW2; 5DX4; 5DY7; 5DYA; 5DYC; 5DYU; 5DYX; 5E3D; 5E3G; 5E73; 5E74; 5E9I; 5E9K; 5E9L; 5E9M; 5E9Y; 5EA1; 5EGU; 5EI4; 5EIS; 5EM3; 5ENB; 5ENC; 5ENE; 5ENF; 5ENH; 5ENI; 5ENJ; 5EPR; 5EPS; 5EQ1; 5ETB; 5ETD; 5EV9; 5EVA; 5EWC; 5EWD; 5EWH; 5FBX; 5FDZ; 5FE0; 5FE1; 5FE2; 5FE3; 5FE4; 5FE5; 5FE6; 5FE7; 5FE8; 5FE9; 5FFV; 5FFW; 5FFY; 5FG4; 5FG5; 5FG6; 5FH6; 5FH7; 5FH8; 5G4R; 5G4S; 5HEL; 5HEM; 5HEN; 5HFQ; 5HFR; 5HJC; 5HLS; 5HM0; 5I1Q; 5I29; 5I83; 5I86; 5I89; 5I8B; 5I8G; 5IBN; 5IG6; 5II1; 5II2; 5IID; 5KHM; 5LJ1; 5LJ2
» more

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