Entry: PS00633

General information about the entry

Entry name [info] BROMODOMAIN_1
Accession [info] PS00633
Entry type [info] PATTERN
Date [info] JUN-1992 (CREATED); DEC-2004 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00550

Name and characterization of the entry

Description [info] Bromodomain signature.
Pattern [info]
[STANVFHG]-x(2)-[FAS]-x(4)-[DNSPAKT]-x(0,7)-[DENQTFG]-Y-[HFYLRKT]-x(2)-
[LIVMFY]-x(3)-[LIVM]-x(4)-[LIVM]-x(6,10)-Y-x(12,13)-[LIVM]-x(2)-N-[SACF]-
x(2)-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 137 in 104 different sequences
Number of true positive hits 137 in 104 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 52
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 72.49 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
104 sequences

ATD2B_HUMAN (Q9ULI0), BAZ1A_HUMAN (Q9NRL2), BAZ1A_MOUSE (O88379), 
BAZ1A_XENLA (Q8UVR5), BAZ1B_HUMAN (Q9UIG0), BAZ1B_MOUSE (Q9Z277), 
BAZ2A_HUMAN (Q9UIF9), BAZ2A_MOUSE (Q91YE5), BAZ2A_XENLA (B7ZS37), 
BAZ2B_CHICK (Q9DE13), BAZ2B_HUMAN (Q9UIF8), BDF1_CANAL  (Q5A4W8), 
BDF1_SCHPO  (Q9Y7N0), BDF1_YEAST  (P35817), BDF2_YEAST  (Q07442), 
BPTF_HUMAN  (Q12830), BRD1_HUMAN  (O95696), BRD2_BOVIN  (Q32S26), 
BRD2_CANFA  (Q5TJG6), BRD2_HUMAN  (P25440), BRD2_MOUSE  (Q7JJ13), 
BRD2_RAT    (Q6MGA9), BRD3_HUMAN  (Q15059), BRD3_MOUSE  (Q8K2F0), 
BRD4A_XENLA (Q08D75), BRD4B_XENLA (Q6DFF2), BRD4_DANRE  (F1R5H6), 
BRD4_HUMAN  (O60885), BRD4_MOUSE  (Q9ESU6), BRD9_XENLA  (Q6GLP7), 
BRD9_XENTR  (Q6NVM8), BRDT_DANRE  (F1QW93), BRDT_HUMAN  (Q58F21), 
BRDT_MACFA  (Q4R8Y1), BRDT_MOUSE  (Q91Y44), BRDT_RAT    (D4A7T3), 
BRDT_XENTR  (F7DRV9), BRM_DROME   (P25439), BRPF1_HUMAN (P55201), 
BRPF3_HUMAN (Q9ULD4), BRWD1_HUMAN (Q9NSI6), BRWD1_MOUSE (Q921C3), 
CBP1_CAEEL  (P34545), CBP_HUMAN   (Q92793), CBP_MOUSE   (P45481), 
CBP_RAT     (Q6JHU9), CECR2_HUMAN (Q9BXF3), EP300_HUMAN (Q09472), 
EP300_MOUSE (B2RWS6), FSH_DROME   (P13709), GCN5_ARATH  (Q9AR19), 
GCN5_ASHGO  (Q756G9), GCN5_CANGA  (Q6FTW5), GCN5_DEBHA  (Q6BGW1), 
GCN5_KLULA  (Q6CXW4), GCN5_ORYSJ  (Q338B9), GCN5_SCHPO  (Q9UUK2), 
GCN5_YARLI  (Q8WZM0), GCN5_YEAST  (Q03330), GTE1_ARATH  (Q84XV2), 
KAT2A_HUMAN (Q92830), KAT2A_MOUSE (Q9JHD2), KAT2B_HUMAN (Q92831), 
KAT2B_MOUSE (Q9JHD1), LIN49_CAEEL (Q20318), NU301_DROME (Q9W0T1), 
PB1_CHICK   (Q90941), PB1_HUMAN   (Q86U86), PB1_MOUSE   (Q8BSQ9), 
PHIP_HUMAN  (Q8WWQ0), PHIP_MOUSE  (Q8VDD9), RSC1_SCHPO  (O74964), 
RSC1_YEAST  (P53236), RSC2_YEAST  (Q06488), RSC4_YEAST  (Q02206), 
SMCA2_HUMAN (P51531), SMCA2_MOUSE (Q6DIC0), SMCA4_BOVIN (A7Z019), 
SMCA4_HUMAN (P51532), SMCA4_MOUSE (Q3TKT4), SMCA4_RAT   (Q8K1P7), 
SNF21_SCHPO (Q9UTN6), SNF22_SCHPO (O94421), SNF2_YEAST  (P22082), 
SPT7_SCHPO  (P87152), SPT7_YEAST  (P35177), STH1_YEAST  (P32597), 
TAF1B_ARATH (Q6PUA2), TAF1L_HUMAN (Q8IZX4), TAF1_ARATH  (Q8LRK9), 
TAF1_DICDI  (Q54DH8), TAF1_DROME  (P51123), TAF1_HUMAN  (P21675), 
TAF1_MESAU  (Q60544), TAF1_MOUSE  (Q80UV9), TAF1_ORYSJ  (Q67W65), 
TBP7_CAEBR  (A8X0L9), TBP7_CAEEL  (P54816), TIF1A_HUMAN (O15164), 
TIF1A_MOUSE (Q64127), Y0170_DICDI (Q55C84), Y1591_ARATH (F4IAE9), 
Y3800_DICDI (Q54BA2), YK82_SCHPO  (Q9HGP4)
» More

UniProtKB/Swiss-Prot
False negative sequences
52 sequences

ASH1L_HUMAN (Q9NR48), ASH1L_MOUSE (Q99MY8), ATAD2_HUMAN (Q6PL18), 
ATAD2_MOUSE (Q8CDM1), BAZ1B_DANRE (A2BIL7), BAZ1B_XENLA (A8DZJ1), 
BDC1_SCHPO  (O74350), BRD7_CHICK  (Q5ZKG2), BRD7_HUMAN  (Q9NPI1), 
BRD7_MOUSE  (O88665), BRD7_PONAB  (Q5R8B0), BRD8_HUMAN  (Q9H0E9), 
BRD8_MOUSE  (Q8R3B7), BRD9_DANRE  (Q7ZUF2), BRD9_HUMAN  (Q9H8M2), 
BRD9_MOUSE  (Q3UQU0), BRM_ARATH   (Q6EVK6), BRWD3_HUMAN (Q6RI45), 
BRWD3_MOUSE (A2AHJ4), GTE10_ARATH (Q9FGW9), GTE11_ARATH (Q93ZB7), 
GTE12_ARATH (Q9LS28), GTE2_ARATH  (Q9LXA7), GTE3_ARATH  (Q9S7T1), 
GTE4_ARATH  (Q9LNC4), GTE5_ARATH  (Q8H1D7), GTE6_ARATH  (Q9FT54), 
GTE7_ARATH  (Q7Y214), GTE8_ARATH  (Q9LK27), GTE9_ARATH  (Q93YS6), 
KMT2A_MOUSE (P55200), MBD9_ARATH  (Q9SGH2), NU301_CAEEL (Q6BER5), 
RSC4_SCHPO  (Q09948), SET1_PLAF7  (C6KTD2), SP110_HUMAN (Q9HB58), 
SP140_HUMAN (Q13342), SP14L_HUMAN (Q9H930), TBP7_YEAST  (P40340), 
TIF1B_HUMAN (Q13263), TIF1B_MOUSE (Q62318), TIF1B_RAT   (O08629), 
TRI33_DANRE (Q6E2N3), TRI33_HUMAN (Q9UPN9), TRI33_XENLA (Q56R14), 
TRI66_HUMAN (O15016), TRI66_MOUSE (Q924W6), Y0777_DICDI (Q54UW4), 
Y1118_DICDI (Q55BK3), Y5837_DICDI (Q54MP8), Y7958_DICDI (Q55FT8), 
Y8469_DICDI (Q54Y18)
» More

PDB
[Detailed view]
243 PDB

1E6I; 1EQF; 1F68; 1JM4; 1JSP; 1N72; 1WUG; 1WUM; 1ZS5; 2D82; 2D9E; 2DAT; 2DKW; 2DVV; 2E3K; 2E7N; 2E7O; 2G4A; 2GRC; 2H60; 2KTB; 2L5E; 2L84; 2L85; 2NXB; 2OO1; 2OSS; 2R0V; 2R10; 2RFJ; 2RI7; 2RNW; 2RNX; 2RNY; 2RS9; 2WP1; 2WP2; 2YDW; 2YEK; 2YEL; 2YQD; 2YW5; 2YYN; 3AAD; 3D7C; 3DWY; 3G0J; 3G0L; 3GG3; 3HMF; 3HMH; 3I3J; 3IU5; 3JVJ; 3JVK; 3K2J; 3LJW; 3LXJ; 3MB3; 3MB4; 3MUK; 3MUL; 3MXF; 3NXB; 3O33; 3O34; 3O35; 3O36; 3O37; 3ONI; 3P1C; 3P1D; 3P1E; 3P1F; 3P5O; 3Q2E; 3Q2F; 3QZS; 3QZT; 3QZV; 3RCW; 3S91; 3S92; 3SVF; 3SVG; 3SVH; 3TLP; 3U5J; 3U5K; 3U5L; 3UV2; 3UV4; 3UV5; 3UVD; 3UVW; 3UVX; 3UVY; 3UW9; 3ZYU; 4A9E; 4A9F; 4A9H; 4A9I; 4A9J; 4A9K; 4A9L; 4A9M; 4A9N; 4A9O; 4AKN; 4ALG; 4ALH; 4BHW; 4BJX; 4BW1; 4BW2; 4BW3; 4BW4; 4C66; 4C67; 4CFK; 4CFL; 4CL9; 4CLB; 4CUP; 4CUQ; 4CUR; 4CUS; 4CUT; 4CUU; 4DON; 4E96; 4F3I; 4FLP; 4GPJ; 4HBV; 4HBW; 4HBX; 4HBY; 4HXK; 4HXL; 4HXM; 4HXN; 4HXO; 4HXP; 4HXR; 4HXS; 4IOO; 4IOQ; 4IOR; 4IR3; 4IR4; 4IR5; 4IR6; 4J0R; 4J0S; 4J1P; 4J3I; 4KCX; 4KV1; 4LC2; 4LR6; 4LRG; 4LYI; 4LYS; 4LYW; 4LZ2; 4LZR; 4LZS; 4MEN; 4MEO; 4MEP; 4MEQ; 4MR3; 4MR4; 4MR5; 4MR6; 4N3W; 4N4F; 4NQM; 4NR4; 4NR5; 4NR6; 4NR7; 4NR8; 4NR9; 4NRA; 4NRB; 4NRC; 4NUC; 4NUD; 4NUE; 4NYV; 4NYW; 4NYX; 4O70; 4O71; 4O72; 4O74; 4O75; 4O76; 4O77; 4O78; 4O7A; 4O7B; 4O7C; 4O7E; 4O7F; 4OGI; 4OGJ; 4OUF; 4PCE; 4PCI; 4PS5; 4Q0N; 4Q0O; 4QB3; 4QBM; 4QC1; 4QC3; 4QEU; 4QEV; 4QEW; 4QYD; 4QYL; 4RVR; 4UIX; 4UIY; 4UIZ; 4UYD; 4UYE; 4UYF; 4UYG; 4UYH; 4WIV; 4XUA; 4XUB; 4XY9; 4XYA; 4Z1Q; 4Z1S; 5AME; 5AMF
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