Entry: PS00633

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General information about the entry

Entry name [info] BROMODOMAIN_1
Accession [info] PS00633
Entry type [info] PATTERN
Date [info] JUN-1992 (CREATED); DEC-2004 (DATA UPDATE); JUL-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00550

Name and characterization of the entry

Description [info] Bromodomain signature.
Pattern [info]
[STANVFHG]-x(2)-[FAS]-x(4)-[DNSPAKT]-x(0,7)-[DENQTFG]-Y-[HFYLRKT]-x(2)-
[LIVMFY]-x(3)-[LIVM]-x(4)-[LIVM]-x(6,10)-Y-x(12,13)-[LIVM]-x(2)-N-[SACF]-
x(2)-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_09 which contains 546'439 sequence entries.


Total number of hits 137 in 104 different sequences
Number of true positive hits 137 in 104 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 52
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 72.49 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
104 sequences

ATD2B_HUMAN (Q9ULI0), BAZ1A_HUMAN (Q9NRL2), BAZ1A_MOUSE (O88379), 
BAZ1A_XENLA (Q8UVR5), BAZ1B_HUMAN (Q9UIG0), BAZ1B_MOUSE (Q9Z277), 
BAZ2A_HUMAN (Q9UIF9), BAZ2A_MOUSE (Q91YE5), BAZ2A_XENLA (B7ZS37), 
BAZ2B_CHICK (Q9DE13), BAZ2B_HUMAN (Q9UIF8), BDF1_CANAL  (Q5A4W8), 
BDF1_SCHPO  (Q9Y7N0), BDF1_YEAST  (P35817), BDF2_YEAST  (Q07442), 
BPTF_HUMAN  (Q12830), BRD1_HUMAN  (O95696), BRD2_BOVIN  (Q32S26), 
BRD2_CANFA  (Q5TJG6), BRD2_HUMAN  (P25440), BRD2_MOUSE  (Q7JJ13), 
BRD2_RAT    (Q6MGA9), BRD3_HUMAN  (Q15059), BRD3_MOUSE  (Q8K2F0), 
BRD4A_XENLA (Q08D75), BRD4B_XENLA (Q6DFF2), BRD4_DANRE  (F1R5H6), 
BRD4_HUMAN  (O60885), BRD4_MOUSE  (Q9ESU6), BRD9_XENLA  (Q6GLP7), 
BRD9_XENTR  (Q6NVM8), BRDT_DANRE  (F1QW93), BRDT_HUMAN  (Q58F21), 
BRDT_MACFA  (Q4R8Y1), BRDT_MOUSE  (Q91Y44), BRDT_RAT    (D4A7T3), 
BRDT_XENTR  (F7DRV9), BRM_DROME   (P25439), BRPF1_HUMAN (P55201), 
BRPF3_HUMAN (Q9ULD4), BRWD1_HUMAN (Q9NSI6), BRWD1_MOUSE (Q921C3), 
CBP1_CAEEL  (P34545), CBP_HUMAN   (Q92793), CBP_MOUSE   (P45481), 
CBP_RAT     (Q6JHU9), CECR2_HUMAN (Q9BXF3), EP300_HUMAN (Q09472), 
EP300_MOUSE (B2RWS6), FSH_DROME   (P13709), GCN5_ARATH  (Q9AR19), 
GCN5_ASHGO  (Q756G9), GCN5_CANGA  (Q6FTW5), GCN5_DEBHA  (Q6BGW1), 
GCN5_KLULA  (Q6CXW4), GCN5_ORYSJ  (Q338B9), GCN5_SCHPO  (Q9UUK2), 
GCN5_YARLI  (Q8WZM0), GCN5_YEAST  (Q03330), GTE1_ARATH  (Q84XV2), 
KAT2A_HUMAN (Q92830), KAT2A_MOUSE (Q9JHD2), KAT2B_HUMAN (Q92831), 
KAT2B_MOUSE (Q9JHD1), LIN49_CAEEL (Q20318), NU301_DROME (Q9W0T1), 
PB1_CHICK   (Q90941), PB1_HUMAN   (Q86U86), PB1_MOUSE   (Q8BSQ9), 
PHIP_HUMAN  (Q8WWQ0), PHIP_MOUSE  (Q8VDD9), RSC1_SCHPO  (O74964), 
RSC1_YEAST  (P53236), RSC2_YEAST  (Q06488), RSC4_YEAST  (Q02206), 
SMCA2_HUMAN (P51531), SMCA2_MOUSE (Q6DIC0), SMCA4_BOVIN (A7Z019), 
SMCA4_HUMAN (P51532), SMCA4_MOUSE (Q3TKT4), SMCA4_RAT   (Q8K1P7), 
SNF21_SCHPO (Q9UTN6), SNF22_SCHPO (O94421), SNF2_YEAST  (P22082), 
SPT7_SCHPO  (P87152), SPT7_YEAST  (P35177), STH1_YEAST  (P32597), 
TAF1B_ARATH (Q6PUA2), TAF1L_HUMAN (Q8IZX4), TAF1_ARATH  (Q8LRK9), 
TAF1_DICDI  (Q54DH8), TAF1_DROME  (P51123), TAF1_HUMAN  (P21675), 
TAF1_MESAU  (Q60544), TAF1_MOUSE  (Q80UV9), TAF1_ORYSJ  (Q67W65), 
TBP7_CAEBR  (A8X0L9), TBP7_CAEEL  (P54816), TIF1A_HUMAN (O15164), 
TIF1A_MOUSE (Q64127), Y0170_DICDI (Q55C84), Y1591_ARATH (F4IAE9), 
Y3800_DICDI (Q54BA2), YK82_SCHPO  (Q9HGP4)
» More

UniProtKB/Swiss-Prot
False negative sequences
52 sequences

ASH1L_HUMAN (Q9NR48), ASH1L_MOUSE (Q99MY8), ATAD2_HUMAN (Q6PL18), 
ATAD2_MOUSE (Q8CDM1), BAZ1B_DANRE (A2BIL7), BAZ1B_XENLA (A8DZJ1), 
BDC1_SCHPO  (O74350), BRD7_CHICK  (Q5ZKG2), BRD7_HUMAN  (Q9NPI1), 
BRD7_MOUSE  (O88665), BRD7_PONAB  (Q5R8B0), BRD8_HUMAN  (Q9H0E9), 
BRD8_MOUSE  (Q8R3B7), BRD9_DANRE  (Q7ZUF2), BRD9_HUMAN  (Q9H8M2), 
BRD9_MOUSE  (Q3UQU0), BRM_ARATH   (Q6EVK6), BRWD3_HUMAN (Q6RI45), 
BRWD3_MOUSE (A2AHJ4), GTE10_ARATH (Q9FGW9), GTE11_ARATH (Q93ZB7), 
GTE12_ARATH (Q9LS28), GTE2_ARATH  (Q9LXA7), GTE3_ARATH  (Q9S7T1), 
GTE4_ARATH  (Q9LNC4), GTE5_ARATH  (Q8H1D7), GTE6_ARATH  (Q9FT54), 
GTE7_ARATH  (Q7Y214), GTE8_ARATH  (Q9LK27), GTE9_ARATH  (Q93YS6), 
KMT2A_MOUSE (P55200), MBD9_ARATH  (Q9SGH2), NU301_CAEEL (Q6BER5), 
RSC4_SCHPO  (Q09948), SET1_PLAF7  (C6KTD2), SP110_HUMAN (Q9HB58), 
SP140_HUMAN (Q13342), SP14L_HUMAN (Q9H930), TBP7_YEAST  (P40340), 
TIF1B_HUMAN (Q13263), TIF1B_MOUSE (Q62318), TIF1B_RAT   (O08629), 
TRI33_DANRE (Q6E2N3), TRI33_HUMAN (Q9UPN9), TRI33_XENLA (Q56R14), 
TRI66_HUMAN (O15016), TRI66_MOUSE (Q924W6), Y0777_DICDI (Q54UW4), 
Y1118_DICDI (Q55BK3), Y5837_DICDI (Q54MP8), Y7958_DICDI (Q55FT8), 
Y8469_DICDI (Q54Y18)
» More

PDB
[Detailed view]
217 PDB

1E6I; 1EQF; 1F68; 1JM4; 1JSP; 1N72; 1WUG; 1WUM; 1ZS5; 2D82; 2D9E; 2DAT; 2DKW; 2DVV; 2E3K; 2E7N; 2E7O; 2G4A; 2GRC; 2H60; 2KTB; 2L5E; 2L84; 2L85; 2NXB; 2OO1; 2OSS; 2R0V; 2R10; 2RFJ; 2RI7; 2RNW; 2RNX; 2RNY; 2RS9; 2WP1; 2WP2; 2YDW; 2YEK; 2YEL; 2YQD; 2YW5; 2YYN; 3AAD; 3D7C; 3DWY; 3G0J; 3G0L; 3GG3; 3HMF; 3HMH; 3I3J; 3IU5; 3JVJ; 3JVK; 3K2J; 3LJW; 3LXJ; 3MB3; 3MB4; 3MUK; 3MUL; 3MXF; 3NXB; 3O33; 3O34; 3O35; 3O36; 3O37; 3ONI; 3P1C; 3P1D; 3P1E; 3P1F; 3P5O; 3Q2E; 3Q2F; 3QZS; 3QZT; 3QZV; 3RCW; 3S91; 3S92; 3SVF; 3SVG; 3SVH; 3TLP; 3U5J; 3U5K; 3U5L; 3UV2; 3UV4; 3UV5; 3UVD; 3UVW; 3UVX; 3UVY; 3UW9; 3ZYU; 4A9E; 4A9F; 4A9H; 4A9I; 4A9J; 4A9K; 4A9L; 4A9M; 4A9N; 4A9O; 4AKN; 4ALG; 4ALH; 4BHW; 4BJX; 4BW1; 4BW2; 4BW3; 4BW4; 4C66; 4C67; 4CFK; 4CFL; 4CUP; 4CUQ; 4CUR; 4CUS; 4CUT; 4CUU; 4DON; 4E96; 4F3I; 4FLP; 4GPJ; 4HBV; 4HBW; 4HBX; 4HBY; 4HXK; 4HXL; 4HXM; 4HXN; 4HXO; 4HXP; 4HXR; 4HXS; 4IOO; 4IOQ; 4IOR; 4IR3; 4IR4; 4IR5; 4IR6; 4J0R; 4J0S; 4J1P; 4J3I; 4KCX; 4KV1; 4LC2; 4LR6; 4LRG; 4LYI; 4LYS; 4LYW; 4LZ2; 4LZR; 4LZS; 4MEN; 4MEO; 4MEP; 4MEQ; 4MR3; 4MR4; 4MR5; 4MR6; 4N3W; 4N4F; 4NQM; 4NR4; 4NR5; 4NR6; 4NR7; 4NR8; 4NR9; 4NRA; 4NRB; 4NRC; 4NUC; 4NUD; 4NUE; 4NYV; 4NYW; 4NYX; 4O70; 4O71; 4O72; 4O74; 4O75; 4O76; 4O77; 4O78; 4O7A; 4O7B; 4O7C; 4O7E; 4O7F; 4OGI; 4OGJ; 4OUF; 4PCE; 4PCI; 4PS5; 4Q0N; 4Q0O; 4QBM; 4QC1; 4QC3
» More

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