Entry: PS00640

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General information about the entry

Entry name [info] THIOL_PROTEASE_ASN
Accession [info] PS00640
Entry type [info] PATTERN
Date [info] JUN-1992 (CREATED); NOV-1995 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00126
Associated ProRule [info] PRU10090

Name and characterization of the entry

Description [info] Eukaryotic thiol (cysteine) proteases asparagine active site.
Pattern [info]
[FYCH]-[WI]-[LIVT]-x-[KRQAG]-N-[ST]-W-x(3)-[FYW]-G-x(2)-G-[LFYW]-
[LIVMFYG]-x-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 181 in 181 different sequences
Number of true positive hits 181 in 181 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 123
Number of 'partial' sequences 25
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 59.54 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
181 sequences

A494_ARATH  (P43295), ACP1_ENTHI  (P36184), ACP2_ENTHI  (P36185), 
ACTN_ACTCH  (P00785), ACTN_ACTDE  (A5HII1), ALEUL_ARATH (Q8RWQ9), 
ALEU_ARATH  (Q8H166), ALEU_HORVU  (P05167), ANAN_ANACO  (P80884), 
BROM1_ANACO (O23791), CATB1_GIAIN (P92131), CATB2_GIAIN (P92132), 
CATB3_GIAIN (P92133), CATB_BOVIN  (P07688), CATB_CHICK  (P43233), 
CATB_HUMAN  (P07858), CATB_MACFA  (Q4R5M2), CATB_MOUSE  (P10605), 
CATB_PIG    (A1E295), CATB_PONAB  (Q5R6D1), CATB_RAT    (P00787), 
CATC_BOVIN  (Q3ZCJ8), CATC_CANFA  (O97578), CATC_HUMAN  (P53634), 
CATC_MACFA  (Q60HG6), CATC_MOUSE  (P97821), CATC_PLAF7  (Q8IIJ9), 
CATC_PONAB  (Q5RB02), CATC_RAT    (P80067), CATH_BOVIN  (Q3T0I2), 
CATH_HUMAN  (P09668), CATH_MOUSE  (P49935), CATH_PIG    (O46427), 
CATH_RAT    (P00786), CATJ_MOUSE  (Q9R014), CATJ_RAT    (Q63088), 
CATK_BOVIN  (Q5E968), CATK_CANFA  (Q3ZKN1), CATK_CHICK  (Q90686), 
CATK_HUMAN  (P43235), CATK_MACFA  (P61276), CATK_MACMU  (P61277), 
CATK_PIG    (Q9GLE3), CATK_RABIT  (P43236), CATK_RAT    (O35186), 
CATL1_BOVIN (P25975), CATL1_CANFA (Q9GL24), CATL1_CHICK (P09648), 
CATL1_CHLAE (Q9GKL8), CATL1_FELCA (P25773), CATL1_HUMAN (P07711), 
CATL1_MOUSE (P06797), CATL1_PIG   (Q28944), CATL1_RAT   (P07154), 
CATL1_SHEEP (Q10991), CATL2_BOVIN (Q5E998), CATL2_HUMAN (O60911), 
CATLL_FASHE (Q24940), CATLL_PHACE (O97397), CATL_BRUPA  (O17473), 
CATL_DROME  (Q95029), CATL_SARPE  (Q26636), CATL_SCHMA  (Q26534), 
CATQ_RAT    (Q9QZE3), CATR_MOUSE  (Q9JIA9), CATS_BOVIN  (P25326), 
CATS_CANFA  (Q8HY81), CATS_HUMAN  (P25774), CATS_MOUSE  (O70370), 
CATS_RAT    (Q02765), CATS_SAIBB  (Q8HY82), CATV_GVCPM  (O91466), 
CATV_GVXN   (Q9PYY5), CATV_NPVAC  (P25783), CATV_NPVAH  (Q80LP4), 
CATV_NPVAP  (Q91CL9), CATV_NPVBM  (P41721), CATV_NPVBS  (Q9YWK4), 
CATV_NPVCD  (Q6VTL7), CATV_NPVCF  (P41715), CATV_NPVEP  (Q91GE3), 
CATV_NPVHC  (Q9WGE0), CATV_NPVHZ  (Q8V5U0), CATV_NPVLD  (Q9YMP9), 
CATV_NPVMC  (Q8QLK1), CATV_NPVOP  (O10364), CATV_NPVR1  (Q8B9D5), 
CATV_NPVSE  (Q9J8B9), CATW_FELCA  (Q9TST1), CATW_HUMAN  (P56202), 
CATW_MOUSE  (P56203), CATZ_BOVIN  (P05689), CATZ_HUMAN  (Q9UBR2), 
CATZ_MOUSE  (Q9WUU7), CATZ_RAT    (Q9R1T3), CEP1_ARATH  (Q9FGR9), 
CEP2_ARATH  (Q9STL4), CEP3_ARATH  (Q9STL5), CPGP1_ZINOF (P82473), 
CPP1_ENTHI  (Q01957), CPP2_ENTHI  (Q01958), CPP3_ENTHI  (Q06964), 
CPR1_ARATH  (Q9LT77), CPR1_CAEEL  (P25807), CPR1_DROME  (Q9VN93), 
CPR2_ARATH  (Q9LXW3), CPR3_CAEEL  (P43507), CPR4_CAEEL  (P43508), 
CPR5_CAEEL  (P43509), CPR6_CAEEL  (P43510), CRUST_PANBO (Q86GF7), 
CYSEP_PHAVU (P25803), CYSEP_RICCO (O65039), CYSEP_VIGMU (P12412), 
CYSP1_DICDI (P04988), CYSP1_HAECO (P19092), CYSP1_HOMAM (P13277), 
CYSP1_HORVU (P25249), CYSP1_LEIPI (P35591), CYSP1_MAIZE (Q10716), 
CYSP1_ORYSJ (Q7XR52), CYSP1_OSTOS (P25802), CYSP2_DICDI (P04989), 
CYSP2_HAECO (P25793), CYSP2_HOMAM (P25782), CYSP2_HORVU (P25250), 
CYSP2_LEIPI (Q05094), CYSP2_MAIZE (Q10717), CYSP3_HOMAM (P25784), 
CYSP3_OSTOS (Q06544), CYSP3_SOLLC (Q40143), CYSP4_BRANA (P25251), 
CYSP4_DICDI (P54639), CYSP5_DICDI (P54640), CYSP6_DICDI (Q94503), 
CYSP7_DICDI (Q94504), CYSP_HEMSP  (P43156), CYSP_PEA    (P25804), 
CYSP_PLAFA  (P25805), CYSP_PLAVN  (P46102), CYSP_PLAVS  (P42666), 
CYSP_SCHJA  (P43157), CYSP_SCHMA  (P25792), CYSP_THEAN  (P25781), 
CYSP_THEPA  (P22497), CYSP_TRYBB  (P14658), CYSP_TRYCR  (P25779), 
ERVB_TABDI  (P60994), ERVC_TABDI  (P83654), GCP1_ARATH  (Q94B08), 
LMCPA_LEIME (P25775), LMCPB_LEIME (P36400), MDO1_PSEMR  (P83443), 
ORYA_ORYSJ  (P25776), ORYB_ORYSJ  (P25777), ORYC_ORYSJ  (P25778), 
P34_SOYBN   (P22895), PAPA1_CARPA (P00784), PAPA2_CARPA (P14080), 
PAPA3_CARPA (P10056), PAPA4_CARPA (P05994), PAPA5_CARPA (P05993), 
PEPT1_DERFA (P16311), PEPT1_DERPT (P08176), PEPT1_EURMA (P25780), 
PEPT1_PSOOV (Q1EIQ3), RD19A_ARATH (P43296), RD21A_ARATH (P43297), 
SAG12_ARATH (Q9FJ47), SAG39_ORYSI (A2XQE8), SAG39_ORYSJ (Q7XWK5), 
SERA_PLAF7  (Q9TY95), SERA_PLAFD  (P69193), SERA_PLAFG  (P69192), 
SILIC_PETFI (Q6YD92), TEST2_MOUSE (Q80UB0), TEST2_RAT   (P15242), 
TINAG_BOVIN (Q3SZI1), TINAG_HUMAN (Q9UJW2), XCP2_ARATH  (Q9LM66), 
YCF2E_CAEEL (P90850)
» More

UniProtKB/Swiss-Prot
False negative sequences
123 sequences

361L_IIV6   (Q91FG3), BLH1_YEAST  (Q01532), BLMH_CHICK  (P87362), 
BLMH_HUMAN  (Q13867), BLMH_RAT    (P70645), BROM2_ANACO (P14518), 
CAN10_HUMAN (Q9HC96), CAN10_MACFA (Q95LP4), CAN10_MOUSE (Q9ESK3), 
CAN10_RAT   (Q9ES66), CAN11_HUMAN (Q9UMQ6), CAN12_HUMAN (Q6ZSI9), 
CAN12_MOUSE (Q9ER56), CAN13_HUMAN (Q6MZZ7), CAN13_MOUSE (Q3UW68), 
CAN13_RAT   (Q5BK10), CAN14_HUMAN (A8MX76), CAN15_HUMAN (O75808), 
CAN15_MOUSE (Q9JLG8), CAN1_BOVIN  (Q27970), CAN1_HUMAN  (P07384), 
CAN1_MACFA  (Q9GLG2), CAN1_MOUSE  (O35350), CAN1_PIG    (P35750), 
CAN1_PONAB  (Q5NVS7), CAN1_RAT    (P97571), CAN2_BOVIN  (Q27971), 
CAN2_CHICK  (Q92178), CAN2_HUMAN  (P17655), CAN2_MACFA  (Q9GLG1), 
CAN2_MOUSE  (O08529), CAN2_RAT    (Q07009), CAN3_BOVIN  (P51186), 
CAN3_CHICK  (Q92177), CAN3_HUMAN  (P20807), CAN3_MACFA  (Q9GLG7), 
CAN3_MOUSE  (Q64691), CAN3_PIG    (P43368), CAN3_RAT    (P16259), 
CAN3_SHEEP  (Q9TTH8), CAN5_CAEEL  (Q22036), CAN5_HUMAN  (O15484), 
CAN5_MOUSE  (O08688), CAN5_RAT    (Q8R4C0), CAN6_HUMAN  (Q9Y6Q1), 
CAN6_MOUSE  (O35646), CAN6_RAT    (O88501), CAN7_HUMAN  (Q9Y6W3), 
CAN7_MOUSE  (Q9R1S8), CAN7_PIG    (A0FKG7), CAN8_HUMAN  (A6NHC0), 
CAN8_MOUSE  (Q91VA3), CAN8_RAT    (Q78EJ9), CAN9_HUMAN  (O14815), 
CAN9_MOUSE  (Q9D805), CAN9_RAT    (O35920), CANA_DROME  (Q11002), 
CANB_DROME  (Q9VT65), CANC_DROME  (Q9VXH6), CAND_DROME  (P27398), 
CANX_CHICK  (P00789), CAN_CAEEL   (P34308), CAN_SCHMA   (P27730), 
CAT7_MOUSE  (Q91ZF2), CAT7_RAT    (D3ZZ07), CATC_SCHMA  (Q26563), 
CATF_HUMAN  (Q9UBX1), CATF_MOUSE  (Q9R013), CATK_MOUSE  (P55097), 
CATL1_PARTE (Q94714), CATL2_PARTE (A0E358), CATL3_PARTE (Q94715), 
CATM_MOUSE  (Q9JL96), CATO_HUMAN  (P43234), CATO_MOUSE  (Q8BM88), 
CATV_NPVST  (Q91BH1), CFAD_DICDI  (Q54TR1), CPGP2_ZINOF (P82474), 
CPLA_DICDI  (Q8MUF9), CPR3_ARATH  (Q9SUT0), CPR4_ARATH  (Q9SUS9), 
CTSB_DICDI  (Q54QD9), CYSP3_DICDI (Q23894), CYSPL_SOLLC (P20721), 
DEK1_ARATH  (Q8RVL2), DEK1_MAIZE  (Q8RVL1), DEK1_ORYSJ  (Q6ZFZ4), 
ECPA_STAEP  (P0C0P9), ECPA_STAEQ  (Q5HKF6), ECPA_STAES  (P0C0Q0), 
GMSA_DICDI  (Q54ME1), MEX1_JACME  (P84346), MEX2_JACME  (P84347), 
PEPC_LACDL  (Q48543), PEPC_LACHE  (Q10744), PEPC_LACLA  (Q9CEG3), 
PEPC_LACLC  (Q04723), PEPC_LISIN  (Q928V0), PEPC_LISMO  (O69192), 
PEPC_STRTR  (Q56115), PEPE_LACHE  (P94870), PEPG_LACDL  (P94869), 
PEPW_LACDL  (P94868), SSPB_STAA8  (Q2FZL3), SSPB_STAAC  (Q5HH36), 
SSPB_STAAM  (Q99V46), SSPB_STAAN  (Q7A6A7), SSPB_STAAR  (Q6GI35), 
SSPB_STAAS  (Q6GAG5), SSPB_STAAU  (P0C1S6), SSPB_STAAW  (Q8NX99), 
SSPP_STAA8  (Q2G2R8), SSPP_STAAC  (Q5HEL3), SSPP_STAAM  (P65825), 
SSPP_STAAN  (P65826), SSPP_STAAR  (Q6GFE8), SSPP_STAAS  (Q6G824), 
SSPP_STAAU  (P81297), SSPP_STAAW  (Q8NVS9), TPR_PORGI   (P25806), 
VF224_IIV3  (Q197D6), VF224_IIV6  (Q91FU7), XCP1_ARATH  (O65493)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
25 sequences

BLMH_RABIT  (P13019), CAL1_CALGI  (P20728), CAN1_RABIT  (P06815), 
CAN2_PIG    (P43367), CAN2_RABIT  (P06814), CATB_COTJA  (P81494), 
CATB_SHEEP  (P83205), CATL1_FASHE (Q09093), CATL2_FASHE (P80342), 
CATL3_FASHE (P80532), CATL4_FASHE (P80528), CATL9_FASHE (P80533), 
CYSB_FASHE  (P80529), CYSP1_CARCN (P32954), CYSP2_CARCN (P32955), 
CYSP3_CARCN (P32956), CYSP4_CARCN (P32957), CYSP_TRIFO  (P33403), 
CYSP_TRIVA  (P33404), HP29_SARPE  (P29184), KARA_BROPL  (P22442), 
MDO2_PSEMR  (P83447), PEPT1_DERMI (P16312), PHIG1_PHIGI (P84789), 
THPA_THADA  (P21381)
» More


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