Entry: PS00640

General information about the entry

Entry name [info] THIOL_PROTEASE_ASN
Accession [info] PS00640
Entry type [info] PATTERN
Date [info] JUN-1992 (CREATED); NOV-1995 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00126
Associated ProRule [info] PRU10090

Name and characterization of the entry

Description [info] Eukaryotic thiol (cysteine) proteases asparagine active site.
Pattern [info]
[FYCH]-[WI]-[LIVT]-x-[KRQAG]-N-[ST]-W-x(3)-[FYW]-G-x(2)-G-[LFYW]-
[LIVMFYG]-x-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 186 in 186 different sequences
Number of true positive hits 186 in 186 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 123
Number of 'partial' sequences 25
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 60.19 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
186 sequences

ACP1_ENTHI  (P36184    ), ACP2_ENTHI  (P36185    ), ACTN_ACTCH  (P00785    ), 
ACTN_ACTDE  (A5HII1    ), ALEUL_ARATH (Q8RWQ9    ), ALEU_ARATH  (Q8H166    ), 
ALEU_HORVU  (P05167    ), ANAN_ANACO  (P80884    ), BROM1_ANACO (O23791    ), 
CATB1_GIAIN (P92131    ), CATB2_GIAIN (P92132    ), CATB3_GIAIN (P92133    ), 
CATB_BOVIN  (P07688    ), CATB_CHICK  (P43233    ), CATB_HUMAN  (P07858    ), 
CATB_MACFA  (Q4R5M2    ), CATB_MOUSE  (P10605    ), CATB_PIG    (A1E295    ), 
CATB_PONAB  (Q5R6D1    ), CATB_RAT    (P00787    ), CATC_BOVIN  (Q3ZCJ8    ), 
CATC_CANLF  (O97578    ), CATC_HUMAN  (P53634    ), CATC_MACFA  (Q60HG6    ), 
CATC_MOUSE  (P97821    ), CATC_PLAF7  (Q8IIJ9    ), CATC_PONAB  (Q5RB02    ), 
CATC_RAT    (P80067    ), CATH_BOVIN  (Q3T0I2    ), CATH_HUMAN  (P09668    ), 
CATH_MOUSE  (P49935    ), CATH_PIG    (O46427    ), CATH_RAT    (P00786    ), 
CATJ_MOUSE  (Q9R014    ), CATJ_RAT    (Q63088    ), CATK_BOVIN  (Q5E968    ), 
CATK_CANLF  (Q3ZKN1    ), CATK_CHICK  (Q90686    ), CATK_HUMAN  (P43235    ), 
CATK_MACFA  (P61276    ), CATK_MACMU  (P61277    ), CATK_PIG    (Q9GLE3    ), 
CATK_RABIT  (P43236    ), CATK_RAT    (O35186    ), CATL1_BOVIN (P25975    ), 
CATL1_CANLF (Q9GL24    ), CATL1_CHICK (P09648    ), CATL1_CHLAE (Q9GKL8    ), 
CATL1_FELCA (P25773    ), CATL1_HUMAN (P07711    ), CATL1_MOUSE (P06797    ), 
CATL1_PIG   (Q28944    ), CATL1_RAT   (P07154    ), CATL1_SHEEP (Q10991    ), 
CATL2_BOVIN (Q5E998    ), CATL2_HUMAN (O60911    ), CATLL_FASHE (Q24940    ), 
CATLL_PHACE (O97397    ), CATL_BRUPA  (O17473    ), CATL_DROME  (Q95029    ), 
CATL_SARPE  (Q26636    ), CATL_SCHMA  (Q26534    ), CATQ_RAT    (Q9QZE3    ), 
CATR_MOUSE  (Q9JIA9    ), CATS_BOVIN  (P25326    ), CATS_CANLF  (Q8HY81    ), 
CATS_HUMAN  (P25774    ), CATS_MOUSE  (O70370    ), CATS_RAT    (Q02765    ), 
CATS_SAIBB  (Q8HY82    ), CATV_GVCPM  (O91466    ), CATV_GVXN   (Q9PYY5    ), 
CATV_NPVAC  (P25783    ), CATV_NPVAH  (Q80LP4    ), CATV_NPVAP  (Q91CL9    ), 
CATV_NPVBM  (P41721    ), CATV_NPVBS  (Q9YWK4    ), CATV_NPVCD  (Q6VTL7    ), 
CATV_NPVCF  (P41715    ), CATV_NPVEP  (Q91GE3    ), CATV_NPVHC  (Q9WGE0    ), 
CATV_NPVHZ  (Q8V5U0    ), CATV_NPVLD  (Q9YMP9    ), CATV_NPVMC  (Q8QLK1    ), 
CATV_NPVOP  (O10364    ), CATV_NPVR1  (Q8B9D5    ), CATV_NPVSE  (Q9J8B9    ), 
CATW_FELCA  (Q9TST1    ), CATW_HUMAN  (P56202    ), CATW_MOUSE  (P56203    ), 
CATZ_BOVIN  (P05689    ), CATZ_HUMAN  (Q9UBR2    ), CATZ_MOUSE  (Q9WUU7    ), 
CATZ_RAT    (Q9R1T3    ), CEP1_ARATH  (Q9FGR9    ), CEP2_ARATH  (Q9STL4    ), 
CEP3_ARATH  (Q9STL5    ), CPGP1_ZINOF (P82473    ), CPP1_ENTHI  (Q01957    ), 
CPP2_ENTHI  (Q01958    ), CPP3_ENTHI  (Q06964    ), CPR1_CAEEL  (P25807    ), 
CPR1_DROME  (Q9VN93    ), CPR3_CAEEL  (P43507    ), CPR4_CAEEL  (P43508    ), 
CPR5_CAEEL  (P43509    ), CPR6_CAEEL  (P43510    ), CRUST_PANBO (Q86GF7    ), 
CYSEP_PHAVU (P25803    ), CYSEP_RICCO (O65039    ), CYSEP_VIGMU (P12412    ), 
CYSP1_DICDI (P04988    ), CYSP1_HAECO (P19092    ), CYSP1_HOMAM (P13277    ), 
CYSP1_HORVU (P25249    ), CYSP1_LEIPI (P35591    ), CYSP1_MAIZE (Q10716    ), 
CYSP1_ORYSJ (Q7XR52    ), CYSP1_OSTOS (P25802    ), CYSP2_DICDI (P04989    ), 
CYSP2_HAECO (P25793    ), CYSP2_HOMAM (P25782    ), CYSP2_HORVU (P25250    ), 
CYSP2_LEIPI (Q05094    ), CYSP2_MAIZE (Q10717    ), CYSP3_HOMAM (P25784    ), 
CYSP3_OSTOS (Q06544    ), CYSP3_SOLLC (Q40143    ), CYSP4_BRANA (P25251    ), 
CYSP4_DICDI (P54639    ), CYSP5_DICDI (P54640    ), CYSP6_DICDI (Q94503    ), 
CYSP7_DICDI (Q94504    ), CYSP_HEMSP  (P43156    ), CYSP_PEA    (P25804    ), 
CYSP_PLAFA  (P25805    ), CYSP_PLAVN  (P46102    ), CYSP_PLAVS  (P42666    ), 
CYSP_SCHJA  (P43157    ), CYSP_SCHMA  (P25792    ), CYSP_THEAN  (P25781    ), 
CYSP_THEPA  (P22497    ), CYSP_TRYBB  (P14658    ), CYSP_TRYCR  (P25779    ), 
ERVB_TABDI  (P60994    ), ERVC_TABDI  (P83654    ), LMCPA_LEIME (P25775    ), 
LMCPB_LEIME (P36400    ), MDO1_PSEMR  (P83443    ), ORYA_ORYSJ  (P25776    ), 
ORYB_ORYSJ  (P25777    ), ORYC_ORYSJ  (P25778    ), P34_SOYBN   (P22895    ), 
PAPA1_CARPA (P00784    ), PAPA2_CARPA (P14080    ), PAPA3_CARPA (P10056    ), 
PAPA4_CARPA (P05994    ), PAPA5_CARPA (P05993    ), PEPT1_DERFA (P16311    ), 
PEPT1_DERPT (P08176    ), PEPT1_EURMA (P25780    ), PEPT1_PSOOV (Q1EIQ3    ), 
RD19A_ARATH (P43296    ), RD19B_ARATH (P43295    ), RD19C_ARATH (Q9SUL1    ), 
RD19D_ARATH (Q8VYS0    ), RD21A_ARATH (P43297    ), RD21B_ARATH (Q9FMH8    ), 
RD21C_ARATH (Q9LT78    ), RDL1_ARATH  (Q94B08    ), RDL2_ARATH  (Q9LT77    ), 
RDL3_ARATH  (Q9LXW3    ), RDL6_ARATH  (F4JNL3    ), SAG12_ARATH (Q9FJ47    ), 
SAG39_ORYSI (A2XQE8    ), SAG39_ORYSJ (Q7XWK5    ), SERA_PLAF7  (Q9TY95    ), 
SERA_PLAFD  (P69193    ), SERA_PLAFG  (P69192    ), SILIC_PETFI (Q6YD92    ), 
TEST2_MOUSE (Q80UB0    ), TEST2_RAT   (P15242    ), TINAG_BOVIN (Q3SZI1    ), 
TINAG_HUMAN (Q9UJW2    ), XCP2_ARATH  (Q9LM66    ), YCF2E_CAEEL (P90850    )
» more

UniProtKB/Swiss-Prot
False negative sequences
123 sequences

361L_IIV6   (Q91FG3    ), BLH1_YEAST  (Q01532    ), BLMH_CHICK  (P87362    ), 
BLMH_HUMAN  (Q13867    ), BLMH_RAT    (P70645    ), BROM2_ANACO (P14518    ), 
CAN10_HUMAN (Q9HC96    ), CAN10_MACFA (Q95LP4    ), CAN10_MOUSE (Q9ESK3    ), 
CAN10_RAT   (Q9ES66    ), CAN11_HUMAN (Q9UMQ6    ), CAN12_HUMAN (Q6ZSI9    ), 
CAN12_MOUSE (Q9ER56    ), CAN13_HUMAN (Q6MZZ7    ), CAN13_MOUSE (Q3UW68    ), 
CAN13_RAT   (Q5BK10    ), CAN14_HUMAN (A8MX76    ), CAN15_HUMAN (O75808    ), 
CAN15_MOUSE (Q9JLG8    ), CAN1_BOVIN  (Q27970    ), CAN1_HUMAN  (P07384    ), 
CAN1_MACFA  (Q9GLG2    ), CAN1_MOUSE  (O35350    ), CAN1_PIG    (P35750    ), 
CAN1_PONAB  (Q5NVS7    ), CAN1_RAT    (P97571    ), CAN2_BOVIN  (Q27971    ), 
CAN2_CHICK  (Q92178    ), CAN2_HUMAN  (P17655    ), CAN2_MACFA  (Q9GLG1    ), 
CAN2_MOUSE  (O08529    ), CAN2_RAT    (Q07009    ), CAN3_BOVIN  (P51186    ), 
CAN3_CHICK  (Q92177    ), CAN3_HUMAN  (P20807    ), CAN3_MACFA  (Q9GLG7    ), 
CAN3_MOUSE  (Q64691    ), CAN3_PIG    (P43368    ), CAN3_RAT    (P16259    ), 
CAN3_SHEEP  (Q9TTH8    ), CAN5_CAEEL  (Q22036    ), CAN5_HUMAN  (O15484    ), 
CAN5_MOUSE  (O08688    ), CAN5_RAT    (Q8R4C0    ), CAN6_HUMAN  (Q9Y6Q1    ), 
CAN6_MOUSE  (O35646    ), CAN6_RAT    (O88501    ), CAN7_HUMAN  (Q9Y6W3    ), 
CAN7_MOUSE  (Q9R1S8    ), CAN7_PIG    (A0FKG7    ), CAN8_HUMAN  (A6NHC0    ), 
CAN8_MOUSE  (Q91VA3    ), CAN8_RAT    (Q78EJ9    ), CAN9_HUMAN  (O14815    ), 
CAN9_MOUSE  (Q9D805    ), CAN9_RAT    (O35920    ), CANA_DROME  (Q11002    ), 
CANB_DROME  (Q9VT65    ), CANC_DROME  (Q9VXH6    ), CAND_DROME  (P27398    ), 
CANX_CHICK  (P00789    ), CAN_CAEEL   (P34308    ), CAN_SCHMA   (P27730    ), 
CAT7_MOUSE  (Q91ZF2    ), CAT7_RAT    (D3ZZ07    ), CATC_SCHMA  (Q26563    ), 
CATF_HUMAN  (Q9UBX1    ), CATF_MOUSE  (Q9R013    ), CATK_MOUSE  (P55097    ), 
CATL1_PARTE (Q94714    ), CATL2_PARTE (A0E358    ), CATL3_PARTE (Q94715    ), 
CATM_MOUSE  (Q9JL96    ), CATO_HUMAN  (P43234    ), CATO_MOUSE  (Q8BM88    ), 
CATV_NPVST  (Q91BH1    ), CFAD_DICDI  (Q54TR1    ), CPGP2_ZINOF (P82474    ), 
CPLA_DICDI  (Q8MUF9    ), CTSB_DICDI  (Q54QD9    ), CYSP3_DICDI (Q23894    ), 
CYSPL_SOLLC (P20721    ), DEK1_ARATH  (Q8RVL2    ), DEK1_MAIZE  (Q8RVL1    ), 
DEK1_ORYSJ  (Q6ZFZ4    ), ECPA_STAEP  (P0C0P9    ), ECPA_STAEQ  (Q5HKF6    ), 
ECPA_STAES  (P0C0Q0    ), GMSA_DICDI  (Q54ME1    ), MEX1_JACME  (P84346    ), 
MEX2_JACME  (P84347    ), PEPC_LACDL  (Q48543    ), PEPC_LACHE  (Q10744    ), 
PEPC_LACLA  (Q9CEG3    ), PEPC_LACLC  (Q04723    ), PEPC_LISIN  (Q928V0    ), 
PEPC_LISMO  (O69192    ), PEPC_STRTR  (Q56115    ), PEPE_LACHE  (P94870    ), 
PEPG_LACDL  (P94869    ), PEPW_LACDL  (P94868    ), RDL4_ARATH  (Q9SUT0    ), 
RDL5_ARATH  (Q9SUS9    ), SSPB_STAA8  (Q2FZL3    ), SSPB_STAAC  (Q5HH36    ), 
SSPB_STAAM  (Q99V46    ), SSPB_STAAN  (Q7A6A7    ), SSPB_STAAR  (Q6GI35    ), 
SSPB_STAAS  (Q6GAG5    ), SSPB_STAAU  (P0C1S6    ), SSPB_STAAW  (Q8NX99    ), 
SSPP_STAA8  (Q2G2R8    ), SSPP_STAAC  (Q5HEL3    ), SSPP_STAAM  (P65825    ), 
SSPP_STAAN  (P65826    ), SSPP_STAAR  (Q6GFE8    ), SSPP_STAAS  (Q6G824    ), 
SSPP_STAAU  (P81297    ), SSPP_STAAW  (Q8NVS9    ), TPR_PORGI   (P25806    ), 
VF224_IIV3  (Q197D6    ), VF224_IIV6  (Q91FU7    ), XCP1_ARATH  (O65493    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
25 sequences

BLMH_RABIT  (P13019    ), CAL1_CALGI  (P20728    ), CAN1_RABIT  (P06815    ), 
CAN2_PIG    (P43367    ), CAN2_RABIT  (P06814    ), CATB_COTJA  (P81494    ), 
CATB_SHEEP  (P83205    ), CATL1_FASHE (Q09093    ), CATL2_FASHE (P80342    ), 
CATL3_FASHE (P80532    ), CATL4_FASHE (P80528    ), CATL9_FASHE (P80533    ), 
CYSB_FASHE  (P80529    ), CYSP1_VASCU (P32954    ), CYSP2_VASCU (P32955    ), 
CYSP3_VASCU (P32956    ), CYSP4_VASCU (P32957    ), CYSP_TRIFO  (P33403    ), 
CYSP_TRIVA  (P33404    ), HP29_SARPE  (P29184    ), KARA_BROPL  (P22442    ), 
MDO2_PSEMR  (P83447    ), PEPT1_DERMI (P16312    ), PHIG1_PHIGI (P84789    ), 
THPA_THADA  (P21381    )
» more

PDB
[Detailed view]
234 PDB

1AEC; 1AIM; 1ATK; 1AU0; 1AU2; 1AU3; 1AU4; 1AYU; 1AYV; 1AYW; 1BGO; 1BP4; 1BQI; 1BY8; 1CJL; 1CPJ; 1CS8; 1CSB; 1CTE; 1CVZ; 1DEU; 1EF7; 1EWL; 1EWM; 1EWO; 1EWP; 1F29; 1F2A; 1F2B; 1F2C; 1FH0; 1GEC; 1GLO; 1GMY; 1HUC; 1ICF; 1ITO; 1IWD; 1JQP; 1K3B; 1KHP; 1KHQ; 1ME3; 1ME4; 1MEG; 1MEM; 1MHW; 1MIR; 1MS6; 1NB3; 1NB5; 1NL6; 1NLJ; 1NPZ; 1NQC; 1O0E; 1PAD; 1PBH; 1PCI; 1PE6; 1PIP; 1POP; 1PPD; 1PPN; 1PPO; 1PPP; 1Q6K; 1QDQ; 1S4V; 1SNK; 1SP4; 1STF; 1THE; 1TU6; 1U9Q; 1U9V; 1U9W; 1U9X; 1VSN; 1XKG; 1YAL; 1YK7; 1YK8; 1YT7; 2ACT; 2AIM; 2AS8; 2ATO; 2AUX; 2AUZ; 2BDL; 2C0Y; 2CIO; 2DC6; 2DC7; 2DC8; 2DC9; 2DCA; 2DCB; 2DCC; 2DCD; 2DJF; 2DJG; 2F1G; 2F7D; 2FO5; 2FTD; 2FYE; 2G6D; 2H7J; 2HH5; 2HHN; 2HXZ; 2IPP; 2NQD; 2O6X; 2OP3; 2OZ2; 2PAD; 2PBH; 2PNS; 2R6N; 2R9M; 2R9N; 2R9O; 2VHS; 2WBF; 2XU1; 2XU3; 2XU4; 2XU5; 2YJ2; 2YJ8; 2YJ9; 2YJB; 2YJC; 3AI8; 3BC3; 3C9E; 3CBJ; 3CBK; 3CH2; 3CH3; 3D6S; 3E1Z; 3H6S; 3H7D; 3H89; 3H8B; 3H8C; 3HD3; 3HHA; 3HWN; 3I06; 3IEJ; 3IMA; 3IUT; 3IV2; 3K24; 3K9M; 3KFQ; 3KKU; 3KSE; 3KW9; 3KWB; 3KWN; 3KWZ; 3KX1; 3LFY; 3LXS; 3MPE; 3MPF; 3N3G; 3N4C; 3O0U; 3O1G; 3OF8; 3OF9; 3OVX; 3OVZ; 3PBH; 3PDF; 3RVV; 3RVW; 3RVX; 3TNX; 3USV; 4AXL; 4AXM; 4BPV; 4BQV; 4BS5; 4BS6; 4BSQ; 4CDC; 4CDD; 4CDE; 4CDF; 4DMX; 4DMY; 4KLB; 4KP9; 4MZO; 4MZS; 4N79; 4N8W; 4OEL; 4OEM; 4P6E; 4P6G; 4PAD; 4PI3; 4PP1; 4PP2; 4QH6; 4QRG; 4QRV; 4QRX; 4W5B; 4W5C; 4X6H; 4X6I; 4X6J; 4XUI; 4YV8; 4YVA; 5F02; 5I4H; 5J94; 5PAD; 6PAD; 7PCK; 8PCH; 9PAP
» more

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