Entry: PS00671

General information about the entry

Entry name [info] D_2_HYDROXYACID_DH_3
Accession [info] PS00671
Entry type [info] PATTERN
Date [info] JUN-1992 (CREATED); APR-2006 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00063

Name and characterization of the entry

Description [info] D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
Pattern [info]
[LMFATCYV]-[KPQNHAR]-x-[GSTDNK]-x-[LIVMFYWRC]-[LIVMFYW](2)-N-x-[STAGC]-R-
[GP]-x-[LIVH]-[LIVMCT]-[DNVE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 325 in 325 different sequences
Number of true positive hits 324 in 324 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 69
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.69 %
Recall (true positives / (true positives + false negatives)) 82.44 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
324 sequences

CTBP1_HUMAN (Q13363    ), CTBP1_MOUSE (O88712    ), CTBP1_RAT   (Q9Z2F5    ), 
CTBP1_XENLA (Q9YHU0    ), CTBP2_BOVIN (Q0VCQ1    ), CTBP2_HUMAN (P56545    ), 
CTBP2_MOUSE (P56546    ), CTBP2_RAT   (Q9EQH5    ), CTBP2_XENLA (Q9W758    ), 
CTBP_DROME  (O46036    ), DDH_HAEIN   (P44501    ), DDH_ZYMMO   (P30799    ), 
DHD2_LACPA  (P17584    ), DHGY_CUCSA  (P13443    ), DHGY_HYPME  (P36234    ), 
DHGY_METEA  (Q59516    ), FDH1_ORYSJ  (Q9SXP2    ), FDH1_YEAS7  (A6ZN46    ), 
FDH1_YEAS8  (C8ZHD6    ), FDH1_YEASC  (N1P3Y5    ), FDH1_YEAST  (Q08911    ), 
FDH2_YEASC  (P0CT22    ), FDH2_YEAST  (P0CF35    ), FDH_ARATH   (Q9S7E4    ), 
FDH_CANBO   (O13437    ), FDH_CHATD   (G0SGU4    ), FDH_EMENI   (Q03134    ), 
FDH_HORVU   (Q9ZRI8    ), FDH_NEUCR   (Q07103    ), FDH_PICAN   (P33677    ), 
FDH_PSESR   (P33160    ), FDH_SOLTU   (Q07511    ), FLDH_CLOS3  (G9EZR6    ), 
GHRA_CITK8  (A8AI49    ), GHRA_CROS8  (A7MFZ8    ), GHRA_ECO27  (B7UP47    ), 
GHRA_ECO45  (B7MIH3    ), GHRA_ECO55  (B7LFE3    ), GHRA_ECO57  (Q8X9K1    ), 
GHRA_ECO5E  (B5YVQ3    ), GHRA_ECO7I  (B7NLA1    ), GHRA_ECO81  (B7MTG4    ), 
GHRA_ECO8A  (B7M907    ), GHRA_ECOBW  (C4ZRX4    ), GHRA_ECODH  (B1X9E7    ), 
GHRA_ECOHS  (A7ZYY6    ), GHRA_ECOK1  (A1A9T1    ), GHRA_ECOL5  (Q0TJ41    ), 
GHRA_ECOL6  (Q8FIT1    ), GHRA_ECOLC  (B1IV68    ), GHRA_ECOLI  (P75913    ), 
GHRA_ECOLU  (B7N3I0    ), GHRA_ECOSE  (B6I9A9    ), GHRA_ECOSM  (B1LIY1    ), 
GHRA_ECOUT  (Q1RDC8    ), GHRA_ESCF3  (B7LTA2    ), GHRA_PHOLL  (Q7N571    ), 
GHRA_SALAR  (A9MH27    ), GHRA_SERP5  (A8GD46    ), GHRA_SHIB3  (B2TTN6    ), 
GHRA_SHIBS  (Q31Z89    ), GHRA_SHIDS  (Q32HN5    ), GHRA_SHISS  (Q3Z393    ), 
GHRB_CITK8  (A8ARD9    ), GHRB_CROS8  (A7MKR1    ), GHRB_ECO24  (A7ZTA0    ), 
GHRB_ECO27  (B7ULB4    ), GHRB_ECO45  (B7MER0    ), GHRB_ECO55  (B7L6W9    ), 
GHRB_ECO57  (P58220    ), GHRB_ECO5E  (B5YVK6    ), GHRB_ECO7I  (B7NP49    ), 
GHRB_ECO81  (B7N1K7    ), GHRB_ECO8A  (B7M3H6    ), GHRB_ECOBW  (C4ZXE2    ), 
GHRB_ECODH  (B1X8G8    ), GHRB_ECOHS  (A8A609    ), GHRB_ECOK1  (A1AH96    ), 
GHRB_ECOL5  (Q0TBP9    ), GHRB_ECOL6  (Q8FCF1    ), GHRB_ECOLC  (B1IZP1    ), 
GHRB_ECOLI  (P37666    ), GHRB_ECOLU  (B7NEK6    ), GHRB_ECOSE  (B6I3C3    ), 
GHRB_ECOSM  (B1LJB3    ), GHRB_ECOUT  (Q1R543    ), GHRB_ENT38  (A4W577    ), 
GHRB_ENTAG  (P58000    ), GHRB_ERWT9  (B2VCD1    ), GHRB_ESCF3  (B7LTG7    ), 
GHRB_KLEP3  (B5XMZ4    ), GHRB_KLEP7  (A6TFG7    ), GHRB_PECAS  (Q6DB24    ), 
GHRB_PECCP  (C6DJ88    ), GHRB_SALA4  (B5EX58    ), GHRB_SALCH  (Q57IH8    ), 
GHRB_SALDC  (B5FLC2    ), GHRB_SALEP  (B5R4N3    ), GHRB_SALHS  (B4T938    ), 
GHRB_SALNS  (B4SWJ5    ), GHRB_SALPA  (Q5PLL9    ), GHRB_SALPB  (A9MUT4    ), 
GHRB_SALPC  (C0Q1A7    ), GHRB_SALPK  (B5BHT3    ), GHRB_SALSV  (B4TZ41    ), 
GHRB_SALTI  (Q8Z2A8    ), GHRB_SALTY  (Q8ZLA1    ), GHRB_SERP5  (A8G7S7    ), 
GHRB_SHIB3  (B2U573    ), GHRB_SHIBS  (Q31V71    ), GHRB_SHIDS  (Q328L4    ), 
GHRB_SHIF8  (Q0SZE5    ), GHRB_SHIFL  (Q83PR3    ), GHRB_SHISS  (Q3YVT5    ), 
GHRB_YERE8  (A1JT62    ), GHRB_YERP3  (A7FPA2    ), GHRB_YERPA  (Q1C3K4    ), 
GHRB_YERPB  (B2K7F1    ), GHRB_YERPE  (Q0W9V5    ), GHRB_YERPG  (A9R4G6    ), 
GHRB_YERPN  (Q1CD80    ), GHRB_YERPP  (A4TGN1    ), GHRB_YERPS  (Q663W4    ), 
GOR1_YEAST  (P53839    ), GRHPR_HUMAN (Q9UBQ7    ), GRHPR_MOUSE (Q91Z53    ), 
GYAR_AERPE  (Q9YAW4    ), GYAR_KORCO  (B1L765    ), GYAR_PYRAB  (Q9UYR1    ), 
GYAR_PYRFU  (Q8U3Y2    ), GYAR_PYRHO  (O58320    ), GYAR_THEGJ  (C5A1V0    ), 
GYAR_THEKO  (Q5JEZ2    ), GYAR_THELN  (Q9C4M5    ), GYAR_THEON  (B6YWH0    ), 
GYAR_THEPD  (A1RYE4    ), LDHD_DICDI  (Q54UF7    ), LDHD_ECOLI  (P52643    ), 
LDHD_LACDA  (P26297    ), LDHD_LACHE  (P30901    ), LDHD_LACPE  (P26298    ), 
LDHD_LACPL  (Q88VJ2    ), LDHD_LEUMC  (P51011    ), LDHD_PEDAC  (Q59642    ), 
LDHD_STAAC  (Q5HD29    ), LDHD_STAAM  (P63940    ), LDHD_STAAN  (P99116    ), 
LDHD_STAAR  (Q6GDS2    ), LDHD_STAAS  (Q6G6F1    ), LDHD_STAAU  (P72357    ), 
LDHD_STAAW  (Q8NUT2    ), LDHD_STAEQ  (Q5HLA0    ), LDHD_STAES  (Q8CN22    ), 
LDHD_STRA3  (Q8E6A9    ), LDHD_STRA5  (Q8E0N5    ), LDHD_STRP1  (Q99ZM2    ), 
LDHD_TREPA  (O83080    ), PDXB_ACIAD  (Q6F943    ), PDXB_ALISL  (B6EIW3    ), 
PDXB_AZOVD  (C1DM66    ), PDXB_BACFN  (Q5LIR8    ), PDXB_BACFR  (Q64ZV5    ), 
PDXB_BACTN  (Q8A2E4    ), PDXB_BLOFL  (Q7VRU9    ), PDXB_BLOPB  (Q492H2    ), 
PDXB_CELJU  (B3PK14    ), PDXB_CITK8  (A8ADQ9    ), PDXB_COXBN  (A9KEY5    ), 
PDXB_COXBR  (A9NAQ7    ), PDXB_COXBU  (Q83AR8    ), PDXB_CROS8  (A7MH63    ), 
PDXB_ECO24  (A7ZPD6    ), PDXB_ECO27  (B7UFX8    ), PDXB_ECO45  (B7MG84    ), 
PDXB_ECO55  (B7LBH4    ), PDXB_ECO57  (Q8XCR0    ), PDXB_ECO5E  (B5YXW1    ), 
PDXB_ECO7I  (B7NP01    ), PDXB_ECO81  (B7MXZ7    ), PDXB_ECO8A  (B7M6K1    ), 
PDXB_ECOBW  (C4ZVL3    ), PDXB_ECODH  (B1X931    ), PDXB_ECOHS  (A8A2I9    ), 
PDXB_ECOK1  (A1ADG9    ), PDXB_ECOL5  (Q0TFC6    ), PDXB_ECOL6  (Q8FFH2    ), 
PDXB_ECOLC  (B1IXM2    ), PDXB_ECOLI  (P05459    ), PDXB_ECOLU  (B7N5T2    ), 
PDXB_ECOSE  (B6I4U8    ), PDXB_ECOSM  (B1LLS6    ), PDXB_ECOUT  (Q1R992    ), 
PDXB_EDWI9  (C5B8N0    ), PDXB_ENT38  (A4WCV4    ), PDXB_ESCF3  (B7LLF0    ), 
PDXB_HAHCH  (Q2SJQ9    ), PDXB_KLEP3  (B5XNR7    ), PDXB_LEGPA  (Q5X6I6    ), 
PDXB_LEGPH  (Q5ZX15    ), PDXB_LEGPL  (Q5WXZ0    ), PDXB_PECAS  (Q6D2N5    ), 
PDXB_PECCP  (C6DA76    ), PDXB_PHOLL  (Q7N2B2    ), PDXB_PHOPR  (Q6LNU2    ), 
PDXB_PROMH  (B4EZF9    ), PDXB_PSE14  (Q48KQ3    ), PDXB_PSEA6  (Q15QG8    ), 
PDXB_PSEA7  (A6V8H9    ), PDXB_PSEA8  (B7UVK4    ), PDXB_PSEAB  (Q02JM2    ), 
PDXB_PSEAE  (Q9I3W9    ), PDXB_PSEE4  (Q1I7B3    ), PDXB_PSEF5  (Q4KFD1    ), 
PDXB_PSEFS  (C3K5G7    ), PDXB_PSEMY  (A4XTK4    ), PDXB_PSEP1  (A5W6I8    ), 
PDXB_PSEPF  (Q3K9D1    ), PDXB_PSEPG  (B0KGD9    ), PDXB_PSEPK  (Q88L20    ), 
PDXB_PSEPW  (B1J5D7    ), PDXB_PSESM  (Q884R9    ), PDXB_PSEU2  (Q4ZVE7    ), 
PDXB_PSEU5  (A4VKJ1    ), PDXB_SALA4  (B5EZQ4    ), PDXB_SALAR  (A9MJ55    ), 
PDXB_SALCH  (Q57LY4    ), PDXB_SALDC  (B5FPL4    ), PDXB_SALEP  (B5R3Q1    ), 
PDXB_SALG2  (B5RCJ5    ), PDXB_SALHS  (B4TBN9    ), PDXB_SALNS  (B4SZP2    ), 
PDXB_SALPA  (Q5PCV8    ), PDXB_SALPB  (A9N474    ), PDXB_SALPC  (C0PZZ3    ), 
PDXB_SALPK  (B5BCH6    ), PDXB_SALSV  (B4TQA6    ), PDXB_SALTI  (P60801    ), 
PDXB_SALTY  (P60802    ), PDXB_SERP5  (A8GH44    ), PDXB_SHEAM  (A1S7K2    ), 
PDXB_SHEB2  (B8EEB4    ), PDXB_SHEB5  (A3D669    ), PDXB_SHEB8  (A6WQ07    ), 
PDXB_SHEB9  (A9KTV0    ), PDXB_SHEFN  (Q084S1    ), PDXB_SHEHH  (B0TKZ7    ), 
PDXB_SHELP  (A3QFC7    ), PDXB_SHEON  (Q8ECR2    ), PDXB_SHEPC  (A4Y882    ), 
PDXB_SHESA  (A0KV91    ), PDXB_SHESH  (A8FTT7    ), PDXB_SHESM  (Q0HKB6    ), 
PDXB_SHESP  (Q56731    ), PDXB_SHESR  (Q0HWL8    ), PDXB_SHESW  (A1RIA7    ), 
PDXB_SHEVD  (Q56733    ), PDXB_SHEWM  (B1KKP1    ), PDXB_SHIB3  (B2TWA2    ), 
PDXB_SHIBS  (Q31YD8    ), PDXB_SHIDS  (Q32DL6    ), PDXB_SHIF8  (Q0T2G5    ), 
PDXB_SHIFL  (Q83QR1    ), PDXB_SHISS  (Q3YZP1    ), PDXB_SODGM  (Q2NSH9    ), 
PDXB_TERTT  (C5BR49    ), PDXB_VIBCH  (Q9KQ92    ), PDXB_VIBF1  (Q5E452    ), 
PDXB_VIBFM  (B5FFP0    ), PDXB_VIBPA  (Q87MN8    ), PDXB_VIBTL  (B7VL81    ), 
PDXB_VIBVU  (Q8DB36    ), PDXB_VIBVY  (Q7MIT6    ), PDXB_WIGBR  (Q8D2P6    ), 
PDXB_YERE8  (A1JL55    ), PDXB_YERP3  (A7FGL9    ), PDXB_YERPA  (Q1C676    ), 
PDXB_YERPB  (B2K8H7    ), PDXB_YERPE  (Q8D0U3    ), PDXB_YERPG  (A9R7V0    ), 
PDXB_YERPN  (Q1CHL8    ), PDXB_YERPP  (A4TM66    ), PDXB_YERPS  (Q668W7    ), 
PDXB_YERPY  (B1JGI0    ), PTXD_PSEST  (O69054    ), SER33_YEAST (P40510    ), 
SERA1_ARATH (O49485    ), SERA2_ARATH (O04130    ), SERA3_ARATH (Q9LT69    ), 
SERA_ARCFU  (O29445    ), SERA_BACSU  (P35136    ), SERA_BOVIN  (Q5EAD2    ), 
SERA_ECO57  (P0A9T2    ), SERA_ECOL6  (P0A9T1    ), SERA_ECOLI  (P0A9T0    ), 
SERA_HAEIN  (P43885    ), SERA_HUMAN  (O43175    ), SERA_MACFA  (Q60HD7    ), 
SERA_METJA  (Q58424    ), SERA_METTH  (O27051    ), SERA_MOUSE  (Q61753    ), 
SERA_MYCBO  (P0A545    ), SERA_MYCLE  (O33116    ), SERA_MYCTO  (P9WNX2    ), 
SERA_MYCTU  (P9WNX3    ), SERA_PANTR  (A5A6P1    ), SERA_PIG    (A5GFY8    ), 
SERA_PONAB  (Q5R7M2    ), SERA_RAT    (O08651    ), SERA_SCHPO  (P87228    ), 
SERA_SHIFL  (P0A9T3    ), SERA_SYNY3  (P73821    ), SERA_YEAST  (P40054    ), 
SLCC_CHRSD  (Q1QWN6    ), VANH_ENTFA  (Q47748    ), VANH_ENTFC  (Q05709    ), 
Y1556_HAEIN (P45250    ), Y1879_STAES (Q8CNB8    ), Y1888_STAEQ (Q5HLU4    ), 
Y2355_CORGL (P0C1E8    ), Y752_STAHJ  (Q4L8G4    ), YEAA_SCHPO  (O14075    ), 
YGDH_SCHPO  (O94574    ), YGT5_YEAST  (P53100    ), YPRB2_CORML (P0C1E9    )
» more

UniProtKB/Swiss-Prot
False negative sequences
69 sequences

2KGR_GLUOX  (Q5FTU6    ), CTBP1_CAEEL (Q20595    ), CTBP_ARATH  (O23702    ), 
DDH_HALMT   (Q2VEQ7    ), FDH2_ORYSJ  (Q67U69    ), GHRA_ENT38  (A4W948    ), 
GHRA_KLEP3  (B5XXL3    ), GHRA_KLEP7  (A6T7B8    ), GHRA_SALA4  (B5F974    ), 
GHRA_SALCH  (Q57QM2    ), GHRA_SALDC  (B5FL30    ), GHRA_SALEP  (B5QY30    ), 
GHRA_SALG2  (B5RBG3    ), GHRA_SALHS  (B4TEQ6    ), GHRA_SALNS  (B4T2W6    ), 
GHRA_SALPA  (Q5PGZ3    ), GHRA_SALPB  (A9N5T3    ), GHRA_SALPC  (C0Q872    ), 
GHRA_SALPK  (B5BBF3    ), GHRA_SALSV  (B4TSP5    ), GHRA_SALTI  (Q8Z7M6    ), 
GHRA_SALTY  (Q8ZQ30    ), GHRA_YERE8  (A1JRR3    ), GHRB_SALG2  (B5RGN1    ), 
GHRB_YERPY  (B1JH01    ), HPR_THEMA   (Q9X1C1    ), PDXB_ACIB3  (B7GY62    ), 
PDXB_ACIB5  (B7I5Z2    ), PDXB_ACIBC  (B2HX89    ), PDXB_ACIBS  (B0VT23    ), 
PDXB_ACIBT  (A3M810    ), PDXB_ACIBY  (B0VDM7    ), PDXB_AERHH  (A0KLP0    ), 
PDXB_AERS4  (A4SNU1    ), PDXB_ALCBS  (Q0VQC3    ), PDXB_BAUCH  (Q1LTA7    ), 
PDXB_CHRSD  (Q1QXV7    ), PDXB_COLP3  (Q47XK1    ), PDXB_IDILO  (Q5QUE2    ), 
PDXB_MARHV  (A1U1I8    ), PDXB_MARMS  (A6VXM3    ), PDXB_PORGI  (Q7MV70    ), 
PDXB_PSEHT  (Q3IF36    ), PDXB_PSYA2  (Q4FV16    ), PDXB_PSYCK  (Q1QE21    ), 
PDXB_PSYIN  (A1SW94    ), PDXB_PSYWF  (A5WHK7    ), PDXB_RUTMC  (A1AWW7    ), 
PDXB_SACD2  (Q21LK8    ), PDXB_SALRD  (Q2S0U3    ), PDXB_SHEDO  (Q12P58    ), 
PDXB_THICR  (Q31IH6    ), PDXB_TOLAT  (C4LF16    ), PDXB_VESOH  (A5CWD1    ), 
SERA_DICDI  (Q54UH8    ), TKRA_BACSU  (O32264    ), TKRA_DICDI  (Q54DP1    ), 
Y2098_STAAN (Q7A417    ), Y2178_STAAB (Q2YYT9    ), Y2196_STAAS (Q6G716    ), 
Y2224_STAAW (Q8NV80    ), Y2254_STAA3 (Q2FEI9    ), Y2296_STAAC (Q5HDQ4    ), 
Y2305_STAAM (Q99RW8    ), Y2389_STAAR (Q6GEC9    ), Y2577_STAA8 (Q2FVW4    ), 
Y606_STAS1  (Q49ZM5    ), YOAD_BACSU  (O34815    ), YP113_YEAST (Q02961    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

YMP5_STRCH  (P43169    )

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

VF030_IIV3  (Q196V4    )

		
PDB
[Detailed view]
48 PDB

1DXY; 1GDH; 1HKU; 1HL3; 1J49; 1J4A; 1MX3; 1PSD; 1YGY; 2DBR; 2DBZ; 2DLD; 2FSS; 2G76; 2GCG; 2GO1; 2GUG; 2HU2; 2J6I; 2NAC; 2NAD; 2O4C; 2OME; 2P9C; 2P9E; 2P9G; 2PA3; 2WWR; 3DC2; 3DDN; 3GA0; 3JTM; 3N7U; 3NAQ; 3OET; 4E5K; 4E5M; 4E5N; 4E5P; 4EBF; 4LCE; 4LCJ; 4NU5; 4NU6; 4U6Q; 4U6S; 5AOV; 5DT9
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission