Entry: PS00697
General information about the entry
Entry nameDNA_LIGASE_A1
Accession numberPS00697
Entry typePATTERN
DateDEC-1992 (CREATED); APR-2006 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00295
Associated ProRulePRU10135
Name and characterization of the entry
DescriptionATP-dependent DNA ligase AMP-binding site.
Pattern[EDQH]-{K}-K-{VEDI}-[DN]-G-{GLYN}-R-[GACIVM].
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 186 hits in 181 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 147 hits in 147 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 39 hits in 34 different sequences
  • Number of known missed hits: 15
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 79.03 %
  • Recall (true hits / (true hits + false negatives)): 90.74 %
Comments
  • Taxonomic range: Archaebacteria, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 4
  • `Interesting' site in the pattern: 3,active_site(?)
  • VERSION: 2
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
DNLI1_ARATH (Q42572), DNLI1_CAEEL (Q27474), DNLI1_DICDI (Q869E1), 
DNLI1_DROME (Q9W1H4), DNLI1_HALWD (Q18HT7), DNLI1_HUMAN (P18858), 
DNLI1_KORCO (B1L3K8), DNLI1_METAC (Q8TSR7), DNLI1_METBF (Q46C04), 
DNLI1_METMA (Q8PVR7), DNLI1_MOUSE (P37913), DNLI1_SCHPO (P12000), 
DNLI1_XENLA (P51892), DNLI1_YEAST (P04819), DNLI2_HALWD (Q18GX5), 
DNLI2_KORCO (B1L3V2), DNLI2_METAC (Q8TMT1), DNLI2_METBF (Q46BA3), 
DNLI2_METMA (Q8PTK1), DNLI2_THEPD (A1RY72), DNLI3_DICDI (Q54QM4), 
DNLI3_HUMAN (P49916), DNLI3_MOUSE (P97386), DNLI3_SCHPO (Q9C1W9), 
DNLI4_ARATH (Q9LL84), DNLI4_ASHGO (Q75CA4), DNLI4_ASPFU (Q4WVG8), 
DNLI4_ASPOR (Q2U6A1), DNLI4_CANAL (P52496), DNLI4_CANGA (Q6FVD8), 
DNLI4_CHICK (Q90YB1), DNLI4_COCIM (Q1DKE7), DNLI4_COPC7 (A8N936), 
DNLI4_COPCI (Q7Z7W5), DNLI4_CRYNB (P0CN09), DNLI4_CRYNJ (P0CN08), 
DNLI4_EMENI (Q5BH83), DNLI4_HUMAN (P49917), DNLI4_MOUSE (Q8BTF7), 
DNLI4_NEUCR (Q7SB49), DNLI4_ORYSJ (Q7X7E9), DNLI4_PHANO (Q0UCI9), 
DNLI4_PONAB (Q5R6L3), DNLI4_SCHPO (O74833), DNLI4_YEAST (Q08387), 
DNLI_ACIAM  (Q02093), DNLI_AERPE  (Q9YD18), DNLI_ANAD2  (B8JBM1), 
DNLI_ANADE  (Q2IH69), DNLI_ANADF  (A7HID3), DNLI_ANASK  (B4UIS1), 
DNLI_AQUAE  (O67398), DNLI_ARCFU  (O29632), DNLI_ARTCA  (B8HCE1), 
DNLI_ASFB7  (P35970), DNLI_ASFK5  (P0C992), DNLI_ASFM2  (P26813), 
DNLI_ASFP4  (P0C990), DNLI_ASFWA  (P0C991), DNLI_BEUC1  (C5BW79), 
DNLI_BPT3   (P07717), DNLI_BPT4   (P00970), DNLI_BPT6   (P19088), 
DNLI_BPT7   (P00969), DNLI_CALMQ  (A8MDU6), DNLI_CENSY  (A0RWD6), 
DNLI_DICT6  (B5YD88), DNLI_DICTD  (B8DZX8), DNLI_FOWPN  (Q67480), 
DNLI_HALLT  (B9LUZ9), DNLI_HALMA  (Q5V4R0), DNLI_HALS3  (B0R4C9), 
DNLI_HALSA  (Q9HR35), DNLI_HYPBU  (A2BJX6), DNLI_IGNH4  (A8AB20), 
DNLI_KINRD  (A6WG40), DNLI_KORVE  (Q1II25), DNLI_META3  (A6UVC4), 
DNLI_METBU  (Q12X08), DNLI_METJA  (Q57635), DNLI_METKA  (Q8TWN3), 
DNLI_METM5  (A4FY19), DNLI_METM6  (A9AAX4), DNLI_METM7  (A6VFQ9), 
DNLI_METMP  (Q6LYM1), DNLI_METS5  (A4YD25), DNLI_METST  (Q2NHF9), 
DNLI_METTF  (P54875), DNLI_METTH  (Q50566), DNLI_METTP  (A0B7F9), 
DNLI_METVS  (A6UNY0), DNLI_MYCA1  (A0QJL0), DNLI_MYCBO  (Q7TTR7), 
DNLI_MYCBP  (A1KN60), DNLI_MYCBT  (C1AGI1), DNLI_MYCGI  (A4TDS2), 
DNLI_MYCMM  (B2HHE1), DNLI_MYCPA  (Q73V97), DNLI_MYCS2  (A0QUP1), 
DNLI_MYCSJ  (A3PXE2), DNLI_MYCSK  (A1UDY9), DNLI_MYCSS  (Q1BB26), 
DNLI_MYCTA  (A5U776), DNLI_MYCTU  (P95096), DNLI_MYCUA  (A0PTC0), 
DNLI_MYCVP  (A1T6P2), DNLI_NATPD  (Q3IPX0), DNLI_NITMS  (A9A3K1), 
DNLI_NOCFA  (Q5YNY7), DNLI_NOCSJ  (A1SKL2), DNLI_NPVLD  (Q9YMV2), 
DNLI_OPITP  (B1ZZL9), DNLI_PERMH  (C0QSL7), DNLI_PYRAB  (P0CL75), 
DNLI_PYRAE  (O93723), DNLI_PYRAR  (A4WH24), DNLI_PYRAY  (P0CL74), 
DNLI_PYRCJ  (A3MS62), DNLI_PYRFU  (P56709), DNLI_PYRHO  (O59288), 
DNLI_PYRIL  (A1RTK4), DNLI_PYRKO  (Q9HHC4), DNLI_RHOOB  (C1AX87), 
DNLI_RHOSR  (Q0SG75), DNLI_SACEN  (A4F870), DNLI_SORC5  (A9GU24), 
DNLI_STAMF  (A3DP49), DNLI_STRAW  (Q826P6), DNLI_STRCO  (Q9FCB1), 
DNLI_STRGG  (B1W5J2), DNLI_SULAC  (Q4JAM1), DNLI_SULIA  (C3MZR1), 
DNLI_SULIK  (C4KIZ2), DNLI_SULIL  (C3MJ14), DNLI_SULIM  (C3MYD2), 
DNLI_SULIN  (C3NF77), DNLI_SULIY  (C3N834), DNLI_SULSH  (Q9P9K9), 
DNLI_SULSO  (Q980T8), DNLI_SULTO  (Q976G4), DNLI_THEFM  (Q9HH07), 
DNLI_THENV  (B1YA52), DNLI_VACCA  (O57250), DNLI_VACCC  (P20492), 
DNLI_VACCW  (P16272), DNLI_VAR67  (P33798), Y1287_AQUAE (O67319)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
DNLI1_RAT   (Q9JHY8), DNLI1_THEPD (A1RXA6), DNLI_HAEIN  (P44121), 
DNLI_METB6  (A7IAA9), DNLI_METHJ  (Q2FTH4), DNLI_METLZ  (A2SR38), 
DNLI_METMJ  (A3CWP1), DNLI_METPE  (B8GGB8), DNLI_METS3  (A5UKX2), 
DNLI_NANEQ  (Q74M64), DNLI_PICTO  (Q6L195), DNLI_THEAC  (Q9HJ26), 
DNLI_THEVO  (Q979A1), DNLI_UNCMA  (Q0W0X1), YKOU_BACSU  (O34398)
False positive hits (sequences which do not belong to the set under consideration):
ACVS_NOCLA  (P27743), ACVS_STRCL  (Q01757), AUBA_PYRKO  (Q5JHN3), 
AUBA_SULAC  (Q4J9H1), BDP1_HUMAN  (A6H8Y1), BDP1_MOUSE  (Q571C7), 
CITS_BACSU  (O34427), COX20_YEAST (Q04935), DDHA_RHOSU  (Q8GPG4), 
DHOM_LACLA  (Q9CGD8), DHOM_LACLC  (P52985), DLTA_LACLA  (Q9CG49), 
DSBC_BORBR  (Q7WEL4), DSBC_BORPA  (Q7W396), DSBC_BORPE  (Q7VU58), 
ERF99_ARATH (Q8L9K1), FABH_PROMM  (Q7V4F6), FOLD_BUCAI  (P57557), 
HAGA1_PORGI (P59915), HAGA2_PORGN (Q51845), INO80_USTMA (Q4PGL2), 
KGP38_PORGN (P72194), KGP66_PORGN (P72197), KGP83_PORGN (Q51817), 
KGP_PORG3   (B2RLK2), KUP_ANADF   (A7H902), MNME_SULNB  (A6QAL0), 
PAL2_SOLTU  (P31426), PDXB_PORGI  (Q7MV70), PKS1_DICDI  (Q55E72), 
QUEA_DEHE1  (Q3Z8C1), RIMM_SYNR3  (A5GQ79), U518_AEDAE  (Q17AI4), 
U518_ANOGA  (Q7PZ36)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1A0I; 1X9N; 2CFM; 2HIV; 2HIX; 3GDE; 3L2P;

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission


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