Entry: PS00708

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General information about the entry

Entry name [info] PRO_ENDOPEP_SER
Accession [info] PS00708
Entry type [info] PATTERN
Date [info] DEC-1992 (CREATED); DEC-1992 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00587
Associated ProRule [info] PRU10084

Name and characterization of the entry

Description [info] Prolyl endopeptidase family serine active site.
Pattern [info]
D-x(3)-A-x(3)-[LIVMFYW]-x(14)-G-x-S-x-G-G-[LIVMFYW](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 44 in 44 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 1
Number of false positive hits 1
Number of false negative sequences 65
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 97.67 %
Recall (true positives / (true positives + false negatives)) 39.25 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
42 sequences

ACPH_BOVIN  (P80227), ACPH_HUMAN  (P13798), ACPH_PIG    (P19205), 
ACPH_RAT    (P13676), APEH_MOUSE  (Q8R146), DAP2_YEAST  (P18962), 
DAPB_ARTBC  (D4AQT0), DAPB_ASPTN  (Q0CXB1), DAPB_NEUCR  (Q7SHU8), 
DAPB_PARBA  (C1GT79), DAPB_PARBD  (C1FZL3), DAPB_PARBP  (C0S7H1), 
DAPB_SORMK  (D1Z9B4), DAPB_TRIVH  (D4DCG0), DPP4_ARTBC  (D4APE2), 
DPP4_ARTOC  (C5FJE3), DPP4_ARTOT  (A0S5V9), DPP4_BOVIN  (P81425), 
DPP4_FELCA  (Q9N2I7), DPP4_HUMAN  (P27487), DPP4_MOUSE  (P28843), 
DPP4_PIG    (P22411), DPP4_RAT    (P14740), DPP4_TRIEQ  (A7UKV8), 
DPP4_TRIRU  (Q5J6J3), DPP4_TRITO  (B6V868), DPP4_TRIVH  (D4CZ59), 
PPCE_AERHY  (Q06903), PPCE_BOVIN  (Q9XTA2), PPCE_DICDI  (Q86AS5), 
PPCE_ELIME  (P27028), PPCE_HUMAN  (P48147), PPCE_MOUSE  (Q9QUR6), 
PPCE_PIG    (P23687), PPCE_RAT    (O70196), PPCF_ELIMR  (P27195), 
PTRB_ECOLI  (P24555), PTRB_MORLA  (Q59536), SEPR_HUMAN  (Q12884), 
SEPR_MOUSE  (P97321), YEA8_SCHPO  (O14073), YTMA_BACSU  (O34493)
» More

UniProtKB/Swiss-Prot
False negative sequences
65 sequences

APEH_AERPE  (Q9YBQ2), CGEP_ARATH  (Q8VZF3), CGEP_ORYSJ  (Q10MJ1), 
DAPB_AJEC8  (F0U7H7), DAPB_AJECG  (C0NUQ8), DAPB_AJECH  (C6HRC7), 
DAPB_AJECN  (A6RBI0), DAPB_AJEDR  (C5GVF3), DAPB_AJEDS  (C5JC30), 
DAPB_ARTGP  (E4UYL6), DAPB_ARTOC  (C5FYZ3), DAPB_ASPCL  (A1CJQ1), 
DAPB_ASPFC  (B0XYK8), DAPB_ASPFN  (B8N076), DAPB_ASPFU  (Q4WX13), 
DAPB_ASPNC  (A2QEK7), DAPB_ASPNG  (Q96VT7), DAPB_ASPOR  (Q2UPW4), 
DAPB_BOTFB  (A6SL49), DAPB_CHAGB  (Q2HF90), DAPB_COCP7  (C5P334), 
DAPB_COCPS  (E9CUF4), DAPB_COLGM  (E3QKD2), DAPB_EMENI  (Q5B934), 
DAPB_GROCL  (F0XS04), DAPB_MAGO7  (A4QYQ5), DAPB_METAQ  (E9ED72), 
DAPB_METAR  (E9ETL5), DAPB_NECH7  (C7YYG9), DAPB_NEOFI  (A1D7R6), 
DAPB_PENCW  (B6HFS8), DAPB_PENMQ  (B6QVW4), DAPB_PHANO  (Q0UVK7), 
DAPB_PODAN  (B2A951), DAPB_PYRTR  (B2WC36), DAPB_PYRTT  (E3S9K3), 
DAPB_SCLS1  (A7EQZ1), DAPB_TALSN  (B8MTH6), DAPB_TUBMM  (D5GM60), 
DAPB_UNCRE  (C4JHY5), DAPB_VERA1  (C9SJ15), DPF1_CAEEL  (Q7JKY3), 
DPF2_CAEEL  (Q18253), DPF6_CAEEL  (P34422), DPP4_ASPCL  (A1CHP1), 
DPP4_ASPFC  (B0Y6C5), DPP4_ASPFN  (B8N970), DPP4_ASPFU  (Q4WPH9), 
DPP4_ASPOR  (Q2UH35), DPP4_EMENI  (Q5AZ42), DPP4_NEOFI  (A1CX29), 
DPP_GIAIN   (Q95WU5), OPH_PSESP   (Q9LCQ7), OPH_SPHS1   (Q588Z2), 
PPCEL_CHICK (Q5ZKL5), PPCEL_HUMAN (Q4J6C6), PPCEL_MACFA (A5LFV8), 
PPCEL_MOUSE (Q8C167), PPCEL_PONAB (Q5RAK4), PPCEL_RAT   (Q5HZA6), 
PPCEL_XENLA (Q32N48), PTP_PORG3   (B2RJX3), PTP_PORGI   (Q7MUW6), 
STE13_YEAST (P33894), VDPP4_APIME (B2D0J4)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

ACPH_RABIT  (P25154)

		
UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

YTAP_BACSU  (O34973)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

NAR1_USTMA  (Q4PAR1)

		
PDB
[Detailed view]
126 PDB

1E5T; 1H2W; 1H2X; 1H2Y; 1J2E; 1N1M; 1NU6; 1NU8; 1O6F; 1O6G; 1ORV; 1ORW; 1PFQ; 1QFM; 1QFS; 1R9M; 1R9N; 1RWQ; 1TK3; 1TKR; 1U8E; 1VZ2; 1VZ3; 1W1I; 1WCY; 1X70; 1Z68; 2AJ8; 2AJB; 2AJC; 2AJD; 2AJL; 2BGN; 2BGR; 2BUA; 2BUB; 2BUC; 2FJP; 2G5P; 2G5T; 2G63; 2GBC; 2GBF; 2GBG; 2GBI; 2HHA; 2I03; 2I3Z; 2I78; 2IIT; 2IIV; 2JID; 2OAE; 2OAG; 2OGZ; 2OLE; 2ONC; 2OPH; 2OQI; 2OQV; 2P8S; 2QJR; 2QKY; 2QOE; 2QT9; 2QTB; 2RGU; 2RIP; 2XDW; 3BJM; 3C43; 3C45; 3CCB; 3CCC; 3D4L; 3DDU; 3EIO; 3EQ7; 3EQ8; 3EQ9; 3F8S; 3G0B; 3G0C; 3G0D; 3G0G; 3H0C; 3HAB; 3HAC; 3KWF; 3KWJ; 3NOX; 3O95; 3O9V; 3OC0; 3OPM; 3Q0T; 3Q8W; 3QBJ; 3SWW; 3SX4; 3VJK; 3VJL; 3VJM; 3W2T; 4A5S; 4AMY; 4AMZ; 4AN0; 4AN1; 4AX4; 4BCB; 4BCC; 4BCD; 4DSA; 4DSZ; 4DTC; 4FFV; 4FFW; 4G1F; 4J3J; 4JH0; 4KR0; 4L72; 4LKO; 4N8D; 4N8E
» More

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