Entry: PS00708

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General information about the entry

Entry name [info] PRO_ENDOPEP_SER
Accession [info] PS00708
Entry type [info] PATTERN
Date [info] DEC-1992 (CREATED); DEC-1992 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00587
Associated ProRule [info] PRU10084

Name and characterization of the entry

Description [info] Prolyl endopeptidase family serine active site.
Pattern [info]
D-x(3)-A-x(3)-[LIVMFYW]-x(14)-G-x-S-x-G-G-[LIVMFYW](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 45 in 45 different sequences
Number of true positive hits 40 in 40 different sequences
Number of 'unknown' hits 1
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 65
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 90.91 %
Recall (true positives / (true positives + false negatives)) 38.10 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
40 sequences

ACPH_BOVIN  (P80227), ACPH_HUMAN  (P13798), ACPH_PIG    (P19205), 
ACPH_RAT    (P13676), APEH_MOUSE  (Q8R146), DAP2_YEAST  (P18962), 
DAPB_ARTBC  (D4AQT0), DAPB_ASPTN  (Q0CXB1), DAPB_NEUCR  (Q7SHU8), 
DAPB_PARBA  (C1GT79), DAPB_PARBD  (C1FZL3), DAPB_PARBP  (C0S7H1), 
DAPB_SORMK  (D1Z9B4), DAPB_TRIVH  (D4DCG0), DPP4_ARTBC  (D4APE2), 
DPP4_ARTOC  (C5FJE3), DPP4_ARTOT  (A0S5V9), DPP4_BOVIN  (P81425), 
DPP4_FELCA  (Q9N2I7), DPP4_HUMAN  (P27487), DPP4_MOUSE  (P28843), 
DPP4_PIG    (P22411), DPP4_RAT    (P14740), DPP4_TRIEQ  (A7UKV8), 
DPP4_TRIRU  (Q5J6J3), DPP4_TRITO  (B6V868), DPP4_TRIVH  (D4CZ59), 
PPCE_AERHY  (Q06903), PPCE_BOVIN  (Q9XTA2), PPCE_DICDI  (Q86AS5), 
PPCE_ELIME  (P27028), PPCE_HUMAN  (P48147), PPCE_MOUSE  (Q9QUR6), 
PPCE_PIG    (P23687), PPCE_RAT    (O70196), PPCF_ELIMR  (P27195), 
PTRB_ECOLI  (P24555), PTRB_MORLA  (Q59536), YEA8_SCHPO  (O14073), 
YTMA_BACSU  (O34493)
» More

UniProtKB/Swiss-Prot
False negative sequences
65 sequences

APEH_AERPE  (Q9YBQ2), CGEP_ARATH  (Q8VZF3), CGEP_ORYSJ  (Q10MJ1), 
DAPB_AJEC8  (F0U7H7), DAPB_AJECG  (C0NUQ8), DAPB_AJECH  (C6HRC7), 
DAPB_AJECN  (A6RBI0), DAPB_AJEDR  (C5GVF3), DAPB_AJEDS  (C5JC30), 
DAPB_ARTGP  (E4UYL6), DAPB_ARTOC  (C5FYZ3), DAPB_ASPCL  (A1CJQ1), 
DAPB_ASPFC  (B0XYK8), DAPB_ASPFN  (B8N076), DAPB_ASPFU  (Q4WX13), 
DAPB_ASPNC  (A2QEK7), DAPB_ASPNG  (Q96VT7), DAPB_ASPOR  (Q2UPW4), 
DAPB_BOTFB  (A6SL49), DAPB_CHAGB  (Q2HF90), DAPB_COCP7  (C5P334), 
DAPB_COCPS  (E9CUF4), DAPB_COLGM  (E3QKD2), DAPB_EMENI  (Q5B934), 
DAPB_GROCL  (F0XS04), DAPB_MAGO7  (A4QYQ5), DAPB_METAQ  (E9ED72), 
DAPB_METAR  (E9ETL5), DAPB_NECH7  (C7YYG9), DAPB_NEOFI  (A1D7R6), 
DAPB_PENCW  (B6HFS8), DAPB_PENMQ  (B6QVW4), DAPB_PHANO  (Q0UVK7), 
DAPB_PODAN  (B2A951), DAPB_PYRTR  (B2WC36), DAPB_PYRTT  (E3S9K3), 
DAPB_SCLS1  (A7EQZ1), DAPB_TALSN  (B8MTH6), DAPB_TUBMM  (D5GM60), 
DAPB_UNCRE  (C4JHY5), DAPB_VERA1  (C9SJ15), DPF1_CAEEL  (Q7JKY3), 
DPF2_CAEEL  (Q18253), DPF6_CAEEL  (P34422), DPP4_ASPCL  (A1CHP1), 
DPP4_ASPFC  (B0Y6C5), DPP4_ASPFN  (B8N970), DPP4_ASPFU  (Q4WPH9), 
DPP4_ASPOR  (Q2UH35), DPP4_EMENI  (Q5AZ42), DPP4_NEOFI  (A1CX29), 
DPP_GIAIN   (Q95WU5), OPH_PSESP   (Q9LCQ7), OPH_SPHS1   (Q588Z2), 
PPCEL_CHICK (Q5ZKL5), PPCEL_HUMAN (Q4J6C6), PPCEL_MACFA (A5LFV8), 
PPCEL_MOUSE (Q8C167), PPCEL_PONAB (Q5RAK4), PPCEL_RAT   (Q5HZA6), 
PPCEL_XENLA (Q32N48), PTP_PORG3   (B2RJX3), PTP_PORGI   (Q7MUW6), 
STE13_YEAST (P33894), VDPP4_APIME (B2D0J4)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

ACPH_RABIT  (P25154)

		
UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

YTAP_BACSU  (O34973)

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

NAR1_USTMA  (Q4PAR1), SEPR_BOVIN  (A5D7B7), SEPR_HUMAN  (Q12884), 
SEPR_MOUSE  (P97321)
» More


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