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PROSITE entry PS00721


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General information about the entry

Entry name [info] FTHFS_1
Accession [info] PS00721
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00595

Name and characterization of the entry

Description [info] Formate--tetrahydrofolate ligase signature 1.
Pattern [info]
[GN]-[LIVMS]-K-G-[GST]-[AG]-[AST]-G-[GAS]-G-[YLHRKF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 297 in 297 different sequences
Number of true positive hits 297 in 297 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 16
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.89 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
297 sequences

C1TC_DROME  (O96553), C1TC_HUMAN  (P11586), C1TC_MOUSE  (Q922D8), 
C1TC_PONAB  (Q5R8P0), C1TC_RAT(P27653), C1TC_SCHPO  (Q8WZJ7), 
C1TC_SPOFR  (Q27772), C1TC_YEAST  (P07245), C1TM_BOVIN  (Q0VCR7), 
C1TM_HUMAN  (Q6UB35), C1TM_MOUSE  (Q3V3R1), C1TM_SCHPO  (O43007), 
C1TM_YEAST  (P09440), FTHS1_DESHY (Q251P8), FTHS1_LACAC (Q5FJY2), 
FTHS1_RUBXD (Q1AXZ4), FTHS1_STRP1 (Q99ZI9), FTHS1_STRP3 (P0DF90), 
FTHS1_STRP6 (Q5XC12), FTHS1_STRP8 (Q8P0X5), FTHS1_STRPB (Q1JBM0), 
FTHS1_STRPC (Q1JLK2), FTHS1_STRPD (Q1JGN8), FTHS1_STRPF (Q1J6F7), 
FTHS1_STRPG (A2REC4), FTHS1_STRPM (Q48TE8), FTHS1_STRPQ (P0DF91), 
FTHS1_STRSV (A3CL27), FTHS2_DESHY (Q24ZZ8), FTHS2_LACAC (Q5FIU5), 
FTHS2_RUBXD (Q1AVP8), FTHS2_STRP1 (Q99XR2), FTHS2_STRP3 (P0DF92), 
FTHS2_STRP6 (Q5X9K7), FTHS2_STRP8 (Q8NZ49), FTHS2_STRPB (Q1J9F2), 
FTHS2_STRPC (Q1JJK1), FTHS2_STRPD (Q1JEK4), FTHS2_STRPF (Q1J4C0), 
FTHS2_STRPG (A2RGS2), FTHS2_STRPM (Q48QZ2), FTHS2_STRPQ (P0DF93), 
FTHS2_STRSV (A3CN49), FTHS3_RUBXD (Q1AT39), FTHS_ACET2  (A3DI22), 
FTHS_ACTP2  (A3MZI4), FTHS_ACTP7  (B3GX43), FTHS_AERHH  (A0KIN9), 
FTHS_AERS4  (A4SPE5), FTHS_AGARV  (C4ZBG8), FTHS_ALIF1  (Q5E3V8), 
FTHS_ALIFM  (B5FG96), FTHS_ALISL  (B6EIJ9), FTHS_ALKOO  (A8MIN1), 
FTHS_ALLAM  (B9JZN5), FTHS_ARATH  (Q9SPK5), FTHS_ARTS2  (A0JZ10), 
FTHS_BACAA  (C3P858), FTHS_BACAC  (C3LKJ6), FTHS_BACAH  (A0RD97), 
FTHS_BACAN  (Q81RE1), FTHS_BACC0  (B7JLG8), FTHS_BACC1  (Q739F4), 
FTHS_BACC2  (B7IUA4), FTHS_BACC3  (C1ES77), FTHS_BACC7  (B7HP29), 
FTHS_BACCQ  (B9IYP4), FTHS_BACCR  (Q81E87), FTHS_BACCZ  (Q63C61), 
FTHS_BACFN  (Q5LD60), FTHS_BACFR  (Q64U80), FTHS_BACHK  (Q6HJK9), 
FTHS_BACLD  (Q65IA6), FTHS_BACP2  (A8FEC9), FTHS_BACTN  (Q8A9S8), 
FTHS_BART1  (A9IM41), FTHS_BIFLO  (Q8G700), FTHS_CALS4  (Q8R7L3), 
FTHS_CAMC1  (A8Z6G1), FTHS_CAMC5  (A7GZZ0), FTHS_CARHZ  (Q3A9K2), 
FTHS_CERS1  (A3PM52), FTHS_CERS4  (Q3J047), FTHS_CERS5  (A4WQ11), 
FTHS_CERSK  (B9KLK4), FTHS_CHESB  (Q11G79), FTHS_CHLAA  (A9WIW3), 
FTHS_CHLAD  (B8GC03), FTHS_CHLSY  (B9LKW0), FTHS_CLOAB  (Q97EB3), 
FTHS_CLOAC  (P13419), FTHS_CLOB1  (A7FZB0), FTHS_CLOB6  (C3KVU4), 
FTHS_CLOB8  (A6LPL1), FTHS_CLOBA  (B2UXU5), FTHS_CLOBB  (B2TI29), 
FTHS_CLOBH  (A5I7P9), FTHS_CLOBJ  (C1FND0), FTHS_CLOBK  (B1IGY1), 
FTHS_CLOBL  (A7GJB8), FTHS_CLOBM  (B1KTC6), FTHS_CLOCY  (Q07064), 
FTHS_CLOD6  (Q189R2), FTHS_CLOK1  (B9DYW1), FTHS_CLOK5  (A5N5B3), 
FTHS_CLONN  (A0PXN0), FTHS_CLOP1  (Q0TMI3), FTHS_CLOPE  (Q8XHL4), 
FTHS_CLOPS  (Q0SQ82), FTHS_CLOTE  (Q891R3), FTHS_CORDI  (Q6NH87), 
FTHS_CORJK  (Q4JVW2), FTHS_CUTAK  (Q6ABS5), FTHS_DEHM1  (Q3Z8K3), 
FTHS_DEHMC  (Q3ZX40), FTHS_DESAH  (C0QAX9), FTHS_DESDA  (B8J0C2), 
FTHS_DESPS  (Q6AL19), FTHS_DESRM  (A4J0S6), FTHS_DINSH  (A8LIR1), 
FTHS_ELUMP  (B2KDK9), FTHS_ENTFA  (Q834D6), FTHS_FERNB  (A7HLZ4), 
FTHS_FINM2  (B0S0G1), FTHS_FUSNN  (Q8RHF4), FTHS_GRABC  (Q0BW57), 
FTHS_HAEDU  (Q7VLW6), FTHS_HALMA  (Q5V5Y2), FTHS_HALOH  (B8D067), 
FTHS_HALWD  (Q18JB5), FTHS_HELMI  (B0TBP1), FTHS_HERA2  (A9B4H8), 
FTHS_HYPNA  (Q0BX04), FTHS_JANSC  (Q28TR4), FTHS_KOSOT  (C5CI89), 
FTHS_LACCB  (B3WEG3), FTHS_LACDA  (Q1GA94), FTHS_LACDB  (Q04AM0), 
FTHS_LACE2  (C4Z1V6), FTHS_LACGA  (Q043I0), FTHS_LACJO  (Q74JC1), 
FTHS_LACLA  (Q9CH07), FTHS_LACLM  (A2RLK1), FTHS_LACLS  (Q02ZS7), 
FTHS_LACP3  (Q038Y4), FTHS_LACP7  (A9KNJ5), FTHS_LACPL  (Q88W76), 
FTHS_LATSS  (Q38X32), FTHS_LAWIP  (Q1MPZ9), FTHS_LEUMM  (Q03YB1), 
FTHS_LEVBA  (Q03S45), FTHS_LIGS1  (Q1WTW0), FTHS_LIMF3  (B2GF64), 
FTHS_LIMRD  (A5VHS9), FTHS_LIMRJ  (B2G5A9), FTHS_LISIN  (Q92AD2), 
FTHS_LISMC  (C1KWH6), FTHS_LISMF  (Q71YD9), FTHS_LISMH  (B8DDM6), 
FTHS_LISMO  (Q8Y624), FTHS_LISW6  (A0AJY2), FTHS_MALP2  (Q8EUQ1), 
FTHS_METC4  (B7L0A5), FTHS_METCA  (Q605Q9), FTHS_METEA  (Q83WS0), 
FTHS_METEP  (A9VZT0), FTHS_METFK  (Q1GZ16), FTHS_METLZ  (A2SS72), 
FTHS_METNO  (B8IBS4), FTHS_METPB  (B1ZJ88), FTHS_METPP  (A2SKX8), 
FTHS_METRJ  (B1M0D1), FTHS_METS4  (B0UQF5), FTHS_METSB  (B8EKB9), 
FTHS_MOOTA  (Q2RM91), FTHS_MOOTH  (P21164), FTHS_NATTJ  (B2A3Q6), 
FTHS_NEIG1  (Q5FAG1), FTHS_NEIG2  (B4RP08), FTHS_NEIM0  (A9M1J1), 
FTHS_NEIMA  (Q9JVY8), FTHS_NEIMB  (Q9JXY2), FTHS_NEIMF  (A1KS57), 
FTHS_NOCSJ  (A1SQH3), FTHS_OENOB  (Q04FS6), FTHS_PAEAT  (A1R8N9), 
FTHS_PARD8  (A6LAR6), FTHS_PARDP  (A1B1M8), FTHS_PEDPA  (Q03FM6), 
FTHS_PELUB  (Q4FL49), FTHS_PEPAC  (Q5XZD9), FTHS_PETMO  (A9BIV8), 
FTHS_PHOPR  (Q6LNJ0), FTHS_PHOV8  (A6L4P0), FTHS_PICTO  (Q6KZM3), 
FTHS_PORGI  (Q7MUZ8), FTHS_PROMH  (B4ET09), FTHS_PSELT  (A8F7D5), 
FTHS_PSYWF  (A5WI04), FTHS_RENSM  (A9WMW3), FTHS_RHIE6  (B3PV59), 
FTHS_RHIEC  (Q2K5P2), FTHS_RHIJ3  (Q1MDG4), FTHS_RHILO  (Q98HQ4), 
FTHS_RHILW  (B5ZYA2), FTHS_RHIME  (Q92N42), FTHS_RHIR8  (B9J7E8), 
FTHS_ROSCS  (A7NGQ9), FTHS_ROSDO  (Q160C2), FTHS_ROSS1  (A5UPV2), 
FTHS_RUEPO  (Q5LNV0), FTHS_RUMCH  (B8I3S9), FTHS_SACEN  (A4FL80), 
FTHS_SHEAM  (A1SAE2), FTHS_SHEB2  (B8ECE1), FTHS_SHEB5  (A3CZY6), 
FTHS_SHEB8  (A6WSY9), FTHS_SHEB9  (A9L3Z6), FTHS_SHELP  (A3QA17), 
FTHS_SHEON  (Q8EJA7), FTHS_SHEPC  (A4YAP3), FTHS_SHEPW  (B8CI99), 
FTHS_SHESA  (A0KSN0), FTHS_SHESH  (A8FQV1), FTHS_SHESM  (Q0HMS6), 
FTHS_SHESR  (Q0HR05), FTHS_SHESW  (A1RFN3), FTHS_SHEWM  (B1KJC0), 
FTHS_SINFN  (C3MFQ8), FTHS_SINMW  (A6UBV0), FTHS_SPHSK  (O66164), 
FTHS_SPIOL  (P28723), FTHS_STAA1  (A7X3G5), FTHS_STAA2  (A6U2J8), 
FTHS_STAA3  (Q2FG06), FTHS_STAA8  (Q2G296), FTHS_STAA9  (A5ITQ4), 
FTHS_STAAB  (Q2YTF6), FTHS_STAAC  (Q5HF42), FTHS_STAAE  (A6QHR5), 
FTHS_STAAM  (Q99TD2), FTHS_STAAN  (Q7A535), FTHS_STAAR  (Q6GFX6), 
FTHS_STAAS  (Q6G8J5), FTHS_STAAT  (A8Z2Q0), FTHS_STAAW  (Q8NW37), 
FTHS_STACT  (B9DN77), FTHS_STAEQ  (Q5HNH4), FTHS_STAES  (Q8CNV9), 
FTHS_STAHJ  (Q4L776), FTHS_STRA1  (Q3K138), FTHS_STRA3  (Q8E5E3), 
FTHS_STRA5  (Q8DZP5), FTHS_STRE4  (C0M9N3), FTHS_STREM  (B4U2T6), 
FTHS_STRMU  (Q59925), FTHS_STRP2  (Q04K90), FTHS_STRP4  (B5E4W4), 
FTHS_STRP7  (C1C7J4), FTHS_STRPI  (B1IC26), FTHS_STRPJ  (B8ZJQ0), 
FTHS_STRPN  (Q97QI2), FTHS_STRPS  (B2IPQ3), FTHS_STRR6  (Q8DPL5), 
FTHS_STRS2  (A4W0G0), FTHS_STRS7  (C0MFU5), FTHS_STRSY  (A4VU67), 
FTHS_STRT1  (Q5M083), FTHS_STRT2  (Q5M4U2), FTHS_STRTD  (Q03L41), 
FTHS_STRU0  (B9DS83), FTHS_STRZJ  (C1CEI6), FTHS_STRZP  (C1CKW9), 
FTHS_STRZT  (C1CR74), FTHS_SYMTH  (Q67JH9), FTHS_SYNAS  (Q2LU82), 
FTHS_SYNWW  (Q0AX38), FTHS_THEAB  (B7IG29), FTHS_THEAC  (Q9HI67), 
FTHS_THEM4  (A6LJS5), FTHS_THEMA  (Q9X287), FTHS_THEP1  (A5ILJ8), 
FTHS_THEP3  (B0KC36), FTHS_THEPX  (B0K5A5), FTHS_THESQ  (B1LAQ7), 
FTHS_THET2  (Q72GY9), FTHS_THEVO  (Q97CL3), FTHS_THEYD  (B5YJE1), 
FTHS_TREDE  (Q73RR6), FTHS_UREPA  (Q9PQS1), FTHS_VIBA3  (B7VSJ2), 
FTHS_VIBC1  (A7N5E9), FTHS_VIBCH  (Q9KLX7), FTHS_VIBPA  (Q87HX2), 
FTHS_VIBVU  (Q8D7D8), FTHS_VIBVY  (Q7MEE8), FTHS_ZYMMO  (Q5NQC7)
» more

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

FTHS_ACHLI  (A9NE95), FTHS_ACICJ  (A5G276), FTHS_BEII9  (B2IC30), 
FTHS_BRAHW  (C0QX38), FTHS_CALBD  (B9MM59), FTHS_CALS8  (A4XIU2), 
FTHS_DESAL  (B8FGU7), FTHS_DESOH  (A8ZZJ0), FTHS_LEUCK  (B1MY45), 
FTHS_MARMM  (Q0APT3), FTHS_MYXXD  (Q1DFW5), FTHS_RUEST  (Q1GE26), 
FTHS_SHEHH  (B0TVP3), FTHS_SHEPA  (A8H8Z4), FTHS_SYNFM  (A0LLR3), 
FTHS_YERE8  (A1JMA3)
» more

PDB
[Detailed view]
14 PDB

1EG7; 1FP7; 1FPM; 3DO6; 3QUS; 4IOJ; 4IOK; 4IOL; 4IOM; 4JIM; 4JJK; 4JJZ; 4JKI; 7C11
» more