PROSITE logo

PROSITE entry PS00722


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] FTHFS_2
Accession [info] PS00722
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00595

Name and characterization of the entry

Description [info] Formate--tetrahydrofolate ligase signature 2.
Pattern [info]
V-[ASV]-[TS]-[IVLA]-[RQ]-[AGS]-[LIM]-[KER]-x-[HN]-[GAS]-[GLKD].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 269 in 269 different sequences
Number of true positive hits 269 in 269 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 43
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.22 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
269 sequences

C1TC_DROME  (O96553), C1TC_HUMAN  (P11586), C1TC_MOUSE  (Q922D8), 
C1TC_PONAB  (Q5R8P0), C1TC_RAT(P27653), C1TC_SCHPO  (Q8WZJ7), 
C1TC_SPOFR  (Q27772), C1TC_YEAST  (P07245), C1TM_BOVIN  (Q0VCR7), 
C1TM_HUMAN  (Q6UB35), C1TM_MOUSE  (Q3V3R1), C1TM_YEAST  (P09440), 
FTHS1_DESHY (Q251P8), FTHS1_RUBXD (Q1AXZ4), FTHS1_STRP1 (Q99ZI9), 
FTHS1_STRP3 (P0DF90), FTHS1_STRP6 (Q5XC12), FTHS1_STRP8 (Q8P0X5), 
FTHS1_STRPB (Q1JBM0), FTHS1_STRPC (Q1JLK2), FTHS1_STRPD (Q1JGN8), 
FTHS1_STRPF (Q1J6F7), FTHS1_STRPG (A2REC4), FTHS1_STRPM (Q48TE8), 
FTHS1_STRPQ (P0DF91), FTHS1_STRSV (A3CL27), FTHS2_DESHY (Q24ZZ8), 
FTHS2_LACAC (Q5FIU5), FTHS2_RUBXD (Q1AVP8), FTHS2_STRP1 (Q99XR2), 
FTHS2_STRP3 (P0DF92), FTHS2_STRP6 (Q5X9K7), FTHS2_STRP8 (Q8NZ49), 
FTHS2_STRPB (Q1J9F2), FTHS2_STRPC (Q1JJK1), FTHS2_STRPD (Q1JEK4), 
FTHS2_STRPF (Q1J4C0), FTHS2_STRPG (A2RGS2), FTHS2_STRPM (Q48QZ2), 
FTHS2_STRPQ (P0DF93), FTHS2_STRSV (A3CN49), FTHS3_RUBXD (Q1AT39), 
FTHS_ACET2  (A3DI22), FTHS_ACICJ  (A5G276), FTHS_AERHH  (A0KIN9), 
FTHS_AERS4  (A4SPE5), FTHS_AGARV  (C4ZBG8), FTHS_ALIF1  (Q5E3V8), 
FTHS_ALIFM  (B5FG96), FTHS_ALISL  (B6EIJ9), FTHS_ALKOO  (A8MIN1), 
FTHS_ALLAM  (B9JZN5), FTHS_ARATH  (Q9SPK5), FTHS_ARTS2  (A0JZ10), 
FTHS_BACAA  (C3P858), FTHS_BACAC  (C3LKJ6), FTHS_BACAH  (A0RD97), 
FTHS_BACAN  (Q81RE1), FTHS_BACC0  (B7JLG8), FTHS_BACC1  (Q739F4), 
FTHS_BACC2  (B7IUA4), FTHS_BACC3  (C1ES77), FTHS_BACC7  (B7HP29), 
FTHS_BACCQ  (B9IYP4), FTHS_BACCR  (Q81E87), FTHS_BACCZ  (Q63C61), 
FTHS_BACFN  (Q5LD60), FTHS_BACFR  (Q64U80), FTHS_BACHK  (Q6HJK9), 
FTHS_BACLD  (Q65IA6), FTHS_BACP2  (A8FEC9), FTHS_BACTN  (Q8A9S8), 
FTHS_BART1  (A9IM41), FTHS_BEII9  (B2IC30), FTHS_BRAHW  (C0QX38), 
FTHS_CALS4  (Q8R7L3), FTHS_CAMC5  (A7GZZ0), FTHS_CARHZ  (Q3A9K2), 
FTHS_CERS1  (A3PM52), FTHS_CERS4  (Q3J047), FTHS_CERS5  (A4WQ11), 
FTHS_CERSK  (B9KLK4), FTHS_CHESB  (Q11G79), FTHS_CHLAA  (A9WIW3), 
FTHS_CHLAD  (B8GC03), FTHS_CHLSY  (B9LKW0), FTHS_CLOAB  (Q97EB3), 
FTHS_CLOAC  (P13419), FTHS_CLOB1  (A7FZB0), FTHS_CLOB6  (C3KVU4), 
FTHS_CLOB8  (A6LPL1), FTHS_CLOBA  (B2UXU5), FTHS_CLOBB  (B2TI29), 
FTHS_CLOBH  (A5I7P9), FTHS_CLOBJ  (C1FND0), FTHS_CLOBK  (B1IGY1), 
FTHS_CLOBL  (A7GJB8), FTHS_CLOBM  (B1KTC6), FTHS_CLOCY  (Q07064), 
FTHS_CLOD6  (Q189R2), FTHS_CLOK1  (B9DYW1), FTHS_CLOK5  (A5N5B3), 
FTHS_CLONN  (A0PXN0), FTHS_CLOP1  (Q0TMI3), FTHS_CLOPE  (Q8XHL4), 
FTHS_CLOPS  (Q0SQ82), FTHS_CLOTE  (Q891R3), FTHS_CORDI  (Q6NH87), 
FTHS_CORJK  (Q4JVW2), FTHS_CUTAK  (Q6ABS5), FTHS_DEHM1  (Q3Z8K3), 
FTHS_DEHMC  (Q3ZX40), FTHS_DESAH  (C0QAX9), FTHS_DESDA  (B8J0C2), 
FTHS_DESPS  (Q6AL19), FTHS_DINSH  (A8LIR1), FTHS_ELUMP  (B2KDK9), 
FTHS_ENTFA  (Q834D6), FTHS_FERNB  (A7HLZ4), FTHS_FUSNN  (Q8RHF4), 
FTHS_GRABC  (Q0BW57), FTHS_HAEDU  (Q7VLW6), FTHS_HALMA  (Q5V5Y2), 
FTHS_HALOH  (B8D067), FTHS_HALWD  (Q18JB5), FTHS_HELMI  (B0TBP1), 
FTHS_HERA2  (A9B4H8), FTHS_HYPNA  (Q0BX04), FTHS_JANSC  (Q28TR4), 
FTHS_KOSOT  (C5CI89), FTHS_LACCB  (B3WEG3), FTHS_LACE2  (C4Z1V6), 
FTHS_LACLA  (Q9CH07), FTHS_LACLM  (A2RLK1), FTHS_LACLS  (Q02ZS7), 
FTHS_LACP3  (Q038Y4), FTHS_LACP7  (A9KNJ5), FTHS_LACPL  (Q88W76), 
FTHS_LATSS  (Q38X32), FTHS_LEUCK  (B1MY45), FTHS_LEUMM  (Q03YB1), 
FTHS_LEVBA  (Q03S45), FTHS_LIGS1  (Q1WTW0), FTHS_LIMF3  (B2GF64), 
FTHS_LIMRD  (A5VHS9), FTHS_LIMRJ  (B2G5A9), FTHS_LISIN  (Q92AD2), 
FTHS_LISMC  (C1KWH6), FTHS_LISMF  (Q71YD9), FTHS_LISMH  (B8DDM6), 
FTHS_LISMO  (Q8Y624), FTHS_LISW6  (A0AJY2), FTHS_MARMM  (Q0APT3), 
FTHS_METC4  (B7L0A5), FTHS_METCA  (Q605Q9), FTHS_METEA  (Q83WS0), 
FTHS_METEP  (A9VZT0), FTHS_METFK  (Q1GZ16), FTHS_METLZ  (A2SS72), 
FTHS_METNO  (B8IBS4), FTHS_METPB  (B1ZJ88), FTHS_METPP  (A2SKX8), 
FTHS_METRJ  (B1M0D1), FTHS_METS4  (B0UQF5), FTHS_METSB  (B8EKB9), 
FTHS_MOOTA  (Q2RM91), FTHS_MOOTH  (P21164), FTHS_MYXXD  (Q1DFW5), 
FTHS_NATTJ  (B2A3Q6), FTHS_NEIG1  (Q5FAG1), FTHS_NEIG2  (B4RP08), 
FTHS_NEIM0  (A9M1J1), FTHS_NEIMA  (Q9JVY8), FTHS_NEIMB  (Q9JXY2), 
FTHS_NEIMF  (A1KS57), FTHS_NOCSJ  (A1SQH3), FTHS_PARD8  (A6LAR6), 
FTHS_PARDP  (A1B1M8), FTHS_PEDPA  (Q03FM6), FTHS_PELUB  (Q4FL49), 
FTHS_PEPAC  (Q5XZD9), FTHS_PETMO  (A9BIV8), FTHS_PHOPR  (Q6LNJ0), 
FTHS_PHOV8  (A6L4P0), FTHS_PICTO  (Q6KZM3), FTHS_PORGI  (Q7MUZ8), 
FTHS_PSELT  (A8F7D5), FTHS_PSYWF  (A5WI04), FTHS_RENSM  (A9WMW3), 
FTHS_RHIE6  (B3PV59), FTHS_RHIEC  (Q2K5P2), FTHS_RHIJ3  (Q1MDG4), 
FTHS_RHILO  (Q98HQ4), FTHS_RHILW  (B5ZYA2), FTHS_RHIME  (Q92N42), 
FTHS_RHIR8  (B9J7E8), FTHS_ROSCS  (A7NGQ9), FTHS_ROSDO  (Q160C2), 
FTHS_ROSS1  (A5UPV2), FTHS_RUEPO  (Q5LNV0), FTHS_RUEST  (Q1GE26), 
FTHS_RUMCH  (B8I3S9), FTHS_SACEN  (A4FL80), FTHS_SHEAM  (A1SAE2), 
FTHS_SHEPW  (B8CI99), FTHS_SINFN  (C3MFQ8), FTHS_SINMW  (A6UBV0), 
FTHS_SPHSK  (O66164), FTHS_SPIOL  (P28723), FTHS_STAA1  (A7X3G5), 
FTHS_STAA2  (A6U2J8), FTHS_STAA3  (Q2FG06), FTHS_STAA8  (Q2G296), 
FTHS_STAA9  (A5ITQ4), FTHS_STAAB  (Q2YTF6), FTHS_STAAC  (Q5HF42), 
FTHS_STAAE  (A6QHR5), FTHS_STAAM  (Q99TD2), FTHS_STAAN  (Q7A535), 
FTHS_STAAR  (Q6GFX6), FTHS_STAAS  (Q6G8J5), FTHS_STAAT  (A8Z2Q0), 
FTHS_STAAW  (Q8NW37), FTHS_STACT  (B9DN77), FTHS_STAEQ  (Q5HNH4), 
FTHS_STAES  (Q8CNV9), FTHS_STAHJ  (Q4L776), FTHS_STRA1  (Q3K138), 
FTHS_STRA3  (Q8E5E3), FTHS_STRA5  (Q8DZP5), FTHS_STRE4  (C0M9N3), 
FTHS_STREM  (B4U2T6), FTHS_STRMU  (Q59925), FTHS_STRP2  (Q04K90), 
FTHS_STRP4  (B5E4W4), FTHS_STRP7  (C1C7J4), FTHS_STRPI  (B1IC26), 
FTHS_STRPJ  (B8ZJQ0), FTHS_STRPN  (Q97QI2), FTHS_STRPS  (B2IPQ3), 
FTHS_STRR6  (Q8DPL5), FTHS_STRS2  (A4W0G0), FTHS_STRS7  (C0MFU5), 
FTHS_STRSY  (A4VU67), FTHS_STRT1  (Q5M083), FTHS_STRT2  (Q5M4U2), 
FTHS_STRTD  (Q03L41), FTHS_STRU0  (B9DS83), FTHS_STRZJ  (C1CEI6), 
FTHS_STRZP  (C1CKW9), FTHS_STRZT  (C1CR74), FTHS_SYMTH  (Q67JH9), 
FTHS_SYNAS  (Q2LU82), FTHS_SYNWW  (Q0AX38), FTHS_THEAC  (Q9HI67), 
FTHS_THEMA  (Q9X287), FTHS_THEP1  (A5ILJ8), FTHS_THEPX  (B0K5A5), 
FTHS_THESQ  (B1LAQ7), FTHS_THET2  (Q72GY9), FTHS_THEVO  (Q97CL3), 
FTHS_VIBA3  (B7VSJ2), FTHS_VIBC1  (A7N5E9), FTHS_VIBCH  (Q9KLX7), 
FTHS_VIBPA  (Q87HX2), FTHS_VIBVU  (Q8D7D8), FTHS_VIBVY  (Q7MEE8), 
FTHS_YERE8  (A1JMA3), FTHS_ZYMMO  (Q5NQC7)
» more

UniProtKB/Swiss-Prot
False negative sequences
43 sequences

FTHS1_LACAC (Q5FJY2), FTHS_ACHLI  (A9NE95), FTHS_ACTP2  (A3MZI4), 
FTHS_ACTP7  (B3GX43), FTHS_BIFLO  (Q8G700), FTHS_CALBD  (B9MM59), 
FTHS_CALS8  (A4XIU2), FTHS_CAMC1  (A8Z6G1), FTHS_DESAL  (B8FGU7), 
FTHS_DESOH  (A8ZZJ0), FTHS_DESRM  (A4J0S6), FTHS_FINM2  (B0S0G1), 
FTHS_LACDA  (Q1GA94), FTHS_LACDB  (Q04AM0), FTHS_LACGA  (Q043I0), 
FTHS_LACJO  (Q74JC1), FTHS_LAWIP  (Q1MPZ9), FTHS_MALP2  (Q8EUQ1), 
FTHS_OENOB  (Q04FS6), FTHS_PAEAT  (A1R8N9), FTHS_PROMH  (B4ET09), 
FTHS_SHEB2  (B8ECE1), FTHS_SHEB5  (A3CZY6), FTHS_SHEB8  (A6WSY9), 
FTHS_SHEB9  (A9L3Z6), FTHS_SHEHH  (B0TVP3), FTHS_SHELP  (A3QA17), 
FTHS_SHEON  (Q8EJA7), FTHS_SHEPA  (A8H8Z4), FTHS_SHEPC  (A4YAP3), 
FTHS_SHESA  (A0KSN0), FTHS_SHESH  (A8FQV1), FTHS_SHESM  (Q0HMS6), 
FTHS_SHESR  (Q0HR05), FTHS_SHESW  (A1RFN3), FTHS_SHEWM  (B1KJC0), 
FTHS_SYNFM  (A0LLR3), FTHS_THEAB  (B7IG29), FTHS_THEM4  (A6LJS5), 
FTHS_THEP3  (B0KC36), FTHS_THEYD  (B5YJE1), FTHS_TREDE  (Q73RR6), 
FTHS_UREPA  (Q9PQS1)
» more

PDB
[Detailed view]
14 PDB

1EG7; 1FP7; 1FPM; 3DO6; 3QUS; 4IOJ; 4IOK; 4IOL; 4IOM; 4JIM; 4JJK; 4JJZ; 4JKI; 7C11
» more