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PROSITE entry PS00741


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General information about the entry

Entry name [info] DH_1
Accession [info] PS00741
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00605

Name and characterization of the entry

Description [info] Dbl homology (DH) domain signature.
Pattern [info]
[LM]-x(2)-[LIVMFYWGS]-[LI]-x(2)-[PEQ]-[LIVMRF]-x(2)-[LIVM]-x-[KRS]-x(2)-
[LT]-x-[LIVM]-x-[DEQN]-[LIVM]-x(3)-[STM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 73 in 73 different sequences
Number of true positive hits 73 in 73 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 125
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 36.87 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
73 sequences

ABR_BOVIN   (A6QNS3), ABR_HUMAN   (Q12979), ABR_MOUSE   (Q5SSL4), 
ABR_RAT (A0A0G2JTR4), ABR_XENLA   (Q8AVG0), ABR_XENTR   (A4II46), 
ARHG3_CHICK (Q5ZLX4), ARHG3_HUMAN (Q9NR81), ARHG3_MACFA (Q9N0A8), 
ARHG3_MOUSE (Q91X46), ARHG3_PONAB (Q5R6F2), ARHG4_HUMAN (Q9NR80), 
ARHG4_MOUSE (Q7TNR9), ARHG5_HUMAN (Q12774), ARHG5_MOUSE (E9Q7D5), 
ARHG6_CHICK (Q5ZLR6), ARHG6_MOUSE (Q8K4I3), ARHG6_RAT   (Q5XXR3), 
ARHG7_HUMAN (Q14155), ARHG7_MOUSE (Q9ES28), ARHG7_RAT   (O55043), 
ARHG8_HUMAN (Q7Z628), ARHG8_MOUSE (Q9Z206), ARHGB_RAT   (Q9ES67), 
ARHGC_HUMAN (Q9NZN5), ARHGC_MOUSE (Q8R4H2), BCR_HUMAN   (P11274), 
BCR_MOUSE   (Q6PAJ1), BCR_RAT (F1LXF1), CDC24_YEAST (P11433), 
DNMBP_CANLF (E2RP94), DNMBP_DANRE (E7F1U2), DNMBP_HUMAN (Q6XZF7), 
DNMBP_MOUSE (Q6TXD4), DNMBP_RAT   (M0R4F8), ECT2_HUMAN  (Q9H8V3), 
ECT2_MOUSE  (Q07139), GEF2_SCHPO  (Q09733), GXCB_DICDI  (Q55E26), 
GXCDD_DICDI (Q1ZXH8), ITSN1_HUMAN (Q15811), ITSN1_MOUSE (Q9Z0R4), 
ITSN1_RAT   (Q9WVE9), ITSN1_XENLA (O42287), MCF2L_HUMAN (O15068), 
MCF2L_MOUSE (Q64096), MCF2L_RAT   (Q63406), MCF2_HUMAN  (P10911), 
OSG1_CAEEL  (Q21653), PREX1_HUMAN (Q8TCU6), PREX1_MOUSE (Q69ZK0), 
PREX2_HUMAN (Q70Z35), PREX2_MOUSE (Q3LAC4), RGRF1_HUMAN (Q13972), 
RGRF1_MOUSE (P27671), RGRF1_RAT   (P28818), SCD1_SCHPO  (P40995), 
SIF1_DROME  (P91621), SIF2_DROME  (P91620), SPT13_MOUSE (Q5DU57), 
TIAM1_HUMAN (Q13009), TIAM1_MOUSE (Q60610), TIAM2_HUMAN (Q8IVF5), 
TIAM2_MOUSE (Q6ZPF3), VAV2_HUMAN  (P52735), VAV2_MOUSE  (Q60992), 
VAV3_HUMAN  (Q9UKW4), VAV3_MOUSE  (Q9R0C8), VAV_BOVIN   (Q08DN7), 
VAV_CAEEL   (Q45FX5), VAV_HUMAN   (P15498), VAV_MOUSE   (P27870), 
VAV_RAT (P54100)
» more

UniProtKB/Swiss-Prot
False negative sequences
125 sequences

AKP13_HUMAN (Q12802), AKP13_MOUSE (E9Q394), AKP13_RAT   (F1M3G7), 
ALS2_HUMAN  (Q96Q42), ALS2_MOUSE  (Q920R0), ALS2_PANTR  (Q5BIW4), 
ALS2_RAT(P0C5Y8), ARG28_HUMAN (Q8N1W1), ARG28_MOUSE (P97433), 
ARG28_RAT   (P0C6P5), ARG33_HUMAN (A8MVX0), ARG33_MOUSE (Q8BW86), 
ARG39_BOVIN (Q0P5E3), ARG39_HUMAN (Q8N4T4), ARG39_MOUSE (Q66JY6), 
ARGAL_BOVIN (Q29RM4), ARGAL_HUMAN (Q9HCE6), ARGAL_MOUSE (A2AWP8), 
ARGAL_PONAB (Q5R5M3), ARH37_HUMAN (A1IGU5), ARH37_MOUSE (A1IGU4), 
ARH37_RAT   (A1IGU3), ARH38_HUMAN (Q9NXL2), ARH38_MOUSE (Q80VK6), 
ARH40_HUMAN (Q8TER5), ARH40_MOUSE (Q3UPH7), ARHG1_HUMAN (Q92888), 
ARHG1_MOUSE (Q61210), ARHG1_RAT   (Q9Z1I6), ARHG2_CANLF (Q865S3), 
ARHG2_HUMAN (Q92974), ARHG2_MOUSE (Q60875), ARHG2_PIG   (B2DCZ9), 
ARHG2_RAT   (Q5FVC2), ARHG6_HUMAN (Q15052), ARHG9_BOVIN (Q58DL7), 
ARHG9_HUMAN (O43307), ARHG9_MOUSE (Q3UTH8), ARHG9_PONAB (Q5RDK0), 
ARHG9_RAT   (Q9QX73), ARHGA_HUMAN (O15013), ARHGA_MOUSE (Q8C033), 
ARHGB_HUMAN (O15085), ARHGF_HUMAN (O94989), ARHGF_MOUSE (Q5FWH6), 
ARHGG_HUMAN (Q5VV41), ARHGG_MOUSE (Q3U5C8), ARHGH_HUMAN (Q96PE2), 
ARHGH_MOUSE (Q80U35), ARHGI_HUMAN (Q6ZSZ5), ARHGI_MOUSE (Q6P9R4), 
ARHGJ_HUMAN (Q8IW93), ARHGJ_MOUSE (Q8BWA8), ARHGP_HUMAN (Q86VW2), 
ARHGP_MOUSE (Q9CWR0), ARHGP_RAT   (Q6P720), ARHGQ_HUMAN (Q96DR7), 
ECT2L_HUMAN (Q008S8), FARP1_CHICK (F1P065), FARP1_HUMAN (Q9Y4F1), 
FARP1_MOUSE (F8VPU2), FARP1_PONAB (Q5RAB8), FARP1_RAT   (F1LYQ8), 
FARP2_HUMAN (O94887), FARP2_MOUSE (Q91VS8), FGD1_HUMAN  (P98174), 
FGD1_MOUSE  (P52734), FGDH_CAEEL  (X5LX76), FUS2_YEAST  (Q05670), 
GEF1_SCHPO  (Q09763), GEF3_SCHPO  (O59679), GEFC_DICDI  (Q8IS20), 
GXCH_DICDI  (Q54J14), GXCI_DICDI  (Q54J11), GXCJJ_DICDI (Q553D3), 
GXCJ_DICDI  (Q54B37), KALRN_HUMAN (O60229), KALRN_RAT   (P97924), 
KXCA_DICDI  (Q54GY6), KXCB_DICDI  (Q54C71), MF2L2_HUMAN (Q86YR7), 
MUG10_SCHPO (P87052), MYOM_DICDI  (Q9TW28), NGEF_HUMAN  (Q8N5V2), 
NGEF_MOUSE  (Q8CHT1), NGEF_PONAB  (Q5RDX5), NGEF_RAT(Q5BKC9), 
OBSCN_DROME (A8DYP0), OBSCN_HUMAN (Q5VST9), OBSCN_MOUSE (A2AAJ9), 
PKH4B_HUMAN (Q96PX9), PKHG1_HUMAN (Q9ULL1), PKHG2_HUMAN (Q9H7P9), 
PKHG2_MOUSE (Q6KAU7), PKHG3_HUMAN (A1L390), PKHG3_MOUSE (Q4VAC9), 
PKHG4_HUMAN (Q58EX7), PKHG5_HUMAN (O94827), PKHG6_HUMAN (Q3KR16), 
PKHG6_MOUSE (Q8R0J1), PKHG7_HUMAN (Q6ZR37), RGF1_SCHPO  (Q9Y7U6), 
RGF2_SCHPO  (Q9UTR5), RGF3_SCHPO  (Q9Y7U5), RGRF2_DANRE (A2CEA7), 
RGRF2_HUMAN (O14827), RGRF2_MOUSE (P70392), RGRF2_RAT   (Q99JE4), 
ROCO5_DICDI (Q1ZXD6), ROM1_YEAST  (P53046), ROM2_YEAST  (P51862), 
SOS1_HUMAN  (Q07889), SOS1_MOUSE  (Q62245), SOS2_HUMAN  (Q07890), 
SOS2_MOUSE  (Q02384), SOS_CAEEL   (Q9N5D3), SOS_DROME   (P26675), 
SPT13_HUMAN (Q96N96), TAG52_CAEEL (Q11100), TRIO_DANRE  (Q1LUA6), 
TRIO_HUMAN  (O75962), TRIO_MOUSE  (Q0KL02), TUS1_YEAST  (Q06412), 
UNC89_CAEEL (O01761), VAV_DROME   (Q9NHV9)
» more

PDB
[Detailed view]
35 PDB

1BY1; 1F5X; 1FOE; 1KI1; 1KZ7; 1KZG; 1LB1; 1RJ2; 1TXD; 1X86; 2DX1; 2PZ1; 2VRW; 2Z0Q; 3BJI; 3EO2; 3JV3; 3KY9; 3QBV; 4XH9; 4YON; 5FI0; 5FI1; 5HZI; 5HZJ; 5HZK; 5N6R; 5N7E; 6L30; 6NEW; 6NF1; 6NFA; 6PCV; 7RX9; 8TUA
» more