Entry: PS00761

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General information about the entry

Entry name [info] SPASE_I_3
Accession [info] PS00761
Entry type [info] PATTERN
Date [info] DEC-1992 (CREATED); APR-2006 (DATA UPDATE); FEB-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00418

Name and characterization of the entry

Description [info] Signal peptidases I signature 3.
Pattern [info]
[LIVMFYW](2)-{NLPA}-{T}-G-D-[NH]-{PIEW}-x(2)-[SND]-x(2)-[SG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_03 which contains 542'782 sequence entries.


Total number of hits 105 in 105 different sequences
Number of true positive hits 87 in 87 different sequences
Number of 'unknown' hits
Number of false positive hits 18 in 18 different sequences
Number of false negative sequences 61
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 82.86 %
Recall (true positives / (true positives + false negatives)) 58.78 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
87 sequences

IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4), IMP2L_HUMAN (Q96T52), 
IMP2L_MOUSE (Q8BPT6), IMP2L_XENLA (Q5PQ63), IMP2_YEAST  (P46972), 
LEP1_BACAM  (P41026), LEP1_SYNY3  (P72660), LEP2_BACAM  (P41025), 
LEP2_SYNY3  (P73157), LEPP_BACNA  (P37943), LEPQ_BACNA  (Q57350), 
LEPS_BACSU  (P28628), LEPT_BACSU  (P71013), LEPU_BACSU  (P42959), 
LEPV_BACSU  (O07560), LEP_AQUAE   (O67088), LEP_BACCL   (P41027), 
LEP_BACLI   (P42668), LEP_BUCAI   (P57347), LEP_BUCAP   (Q8K9R0), 
LEP_BUCBP   (Q89AM6), LEP_ECOLI   (P00803), LEP_HAEIN   (P44454), 
LEP_HELPJ   (Q9ZLQ5), LEP_HELPY   (O25300), LEP_MYCLE   (O33021), 
LEP_MYCTU   (Q10789), LEP_PHOLA   (Q51876), LEP_PSEAE   (Q9I5G7), 
LEP_PSEFL   (P26844), LEP_RICAH   (A8GM78), LEP_RICB8   (A8GYE1), 
LEP_RICBR   (Q1RHA1), LEP_RICCK   (A8EXI2), LEP_RICCN   (Q92JB1), 
LEP_RICFE   (Q4UKA7), LEP_RICM5   (A8F0M1), LEP_RICPR   (Q9ZE32), 
LEP_RICRS   (A8GQT7), LEP_RICTY   (Q8L2J7), LEP_SALTI   (P0A1W3), 
LEP_SALTY   (P0A1W2), LEP_STAAC   (Q5HHB9), LEP_STAAM   (P0A067), 
LEP_STAAN   (P0A068), LEP_STAAR   (Q6GIC3), LEP_STAAS   (Q6GAW1), 
LEP_STAAU   (P0A070), LEP_STAAW   (P0A069), PLSP1_ARATH (Q8H0W1), 
SC11A_BOVIN (P67810), SC11A_CANFA (P67811), SC11A_HUMAN (P67812), 
SC11A_MOUSE (Q9R0P6), SC11A_PONAB (Q5R9C7), SC11A_RAT   (P42667), 
SC11B_HUMAN (P0C7V7), SC11C_CANFA (P13679), SC11C_HUMAN (Q9BY50), 
SC11C_MOUSE (Q9D8V7), SC11C_PONAB (Q5RC30), SC11C_RAT   (Q9WTR7), 
SEC11_CANAL (Q5A869), SEC11_CANAW (C4YNJ0), SEC11_CANDC (B9WKT4), 
SEC11_CANTT (C5M4J6), SEC11_CLAL4 (C4Y3D4), SEC11_DEBHA (Q6BP15), 
SEC11_LODEL (A5DS09), SEC11_PICGU (A5DIZ8), SEC11_PICPG (C4QXP7), 
SEC11_PICST (A3LXS1), SEC11_SCHCM (D8Q7Q5), SEC11_YARLI (Q6CAG9), 
SEC11_YEAS1 (B3LTI7), SEC11_YEAS2 (C7GLT4), SEC11_YEAS7 (A6ZVU2), 
SEC11_YEAS8 (C8ZAS4), SEC11_YEASA (E7KDY6), SEC11_YEASB (E7Q587), 
SEC11_YEASL (E7KQ01), SEC11_YEAST (P15367), SEC11_YEASV (E7LVX4), 
SEC11_YEASZ (E7QG89), TPP1_ARATH  (O04348), TPP2_ARATH  (Q9M9Z2)
» More

UniProtKB/Swiss-Prot
False negative sequences
61 sequences

IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39), 
IMP1_YEAST  (P28627), IMP2L_SCHPO (Q9UST2), LEPH_STAAC  (Q5HHC0), 
LEPH_STAAM  (P0A063), LEPH_STAAN  (P0A064), LEPH_STAAR  (Q6GIC4), 
LEPH_STAAS  (Q6GAW2), LEPH_STAAU  (P0A066), LEPH_STAAW  (P0A065), 
LEP_STRPN   (O07344), LEP_STRR6   (P59662), SEC11_AJEC8 (F0UDD2), 
SEC11_AJECG (C0NKT8), SEC11_AJECH (C6HB29), SEC11_AJECN (A6QX24), 
SEC11_AJEDR (C5G8L5), SEC11_AJEDS (C5JJG5), SEC11_ARTBC (D4ALL0), 
SEC11_ARTGP (E4V4X0), SEC11_ARTOC (C5FQ45), SEC11_ASHGO (Q759W4), 
SEC11_ASPCL (A1CL29), SEC11_ASPFC (B0XWT3), SEC11_ASPFU (Q4WYF4), 
SEC11_ASPOR (Q2UBW3), SEC11_ASPTN (Q0CQC5), SEC11_CHAGB (Q2H1P3), 
SEC11_COCP7 (C5PA33), SEC11_COCPS (E9CXH2), SEC11_COLGM (E3QXY4), 
SEC11_EMENI (Q5B8K4), SEC11_GROCL (F0XJH4), SEC11_KLULA (Q6CMR5), 
SEC11_LACBS (B0D4L0), SEC11_LACTC (C5DDH1), SEC11_LEPMJ (E5A8D2), 
SEC11_MAGO7 (A4RGA1), SEC11_METAQ (E9E796), SEC11_METAR (E9F8V9), 
SEC11_NECH7 (C7ZHK5), SEC11_NEOFI (A1D6D8), SEC11_NEUCR (Q7RY44), 
SEC11_OGAPD (E7R7C4), SEC11_PARBA (C1GU90), SEC11_PARBD (C1FYD2), 
SEC11_PARBP (C0S3S0), SEC11_PENCW (B6HC89), SEC11_PENMQ (B6Q5G0), 
SEC11_PODAN (B2B3T2), SEC11_PYRTR (B2WEL2), SEC11_PYRTT (E3RR70), 
SEC11_SCLS1 (A7E716), SEC11_TALSN (B8M5K5), SEC11_TRIVH (D4D5I1), 
SEC11_TUBMM (D5GNC3), SEC11_UNCRE (C4JYM4), SEC11_VERA1 (C9S8G0), 
SEC11_ZYGRC (C5E3W1)
» More

UniProtKB/Swiss-Prot
False positive sequences
18 sequences

ACSA_PASMU  (Q9CMW1), ADPRL_MIMIV (Q5UQP4), C508D_DICDI (Q1ZXA4), 
CBIK_SALTY  (Q05592), CCDC9_MOUSE (Q8VC31), CT54_CONVE  (Q9BPF7), 
DGOK_ECOLI  (P31459), GLNA1_DICDI (Q86B00), HLDE_DICNV  (A5EWS4), 
MYO7B_MOUSE (Q99MZ6), NACA_DICDI  (Q54U07), OADC_BURXL  (Q13Q00), 
PUM8_ARATH  (Q9LM20), PURT_ACIAD  (Q6FAM6), RECA_IDILO  (Q5QUB8), 
SYR_OCEIH   (Q8EM45), TCPH_PLAF7  (O77323), Y309_MYCGE  (P47551)
» More

PDB
[Detailed view]
5 PDB

1B12; 1KN9; 1T7D; 3IIQ; 3S04

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