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Entry: PS00778

General information about the entry

Entry name [info] HIS_ACID_PHOSPHAT_2
Accession [info] PS00778
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED; 01-APR-2006 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00538

Name and characterization of the entry

Description [info] Histidine acid phosphatases active site signature.
Pattern [info]
[LIVMF]-x-[LIVMFAG]-{T}-x-[STAGI]-H-D-[STANQ]-{V}-[LIVM]-x(2)-[LIVMFY]-
x(2)-[STA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 88 in 88 different sequences
Number of true positive hits 45 in 45 different sequences
Number of 'unknown' hits 0
Number of false positive hits 43 in 43 different sequences
Number of false negative sequences 32
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 51.14 %
Recall (true positives / (true positives + false negatives)) 58.44 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
45 sequences

AGP_ECOLI   (P19926    ), AGP_PRORE   (Q52309    ), AGP_SALTY   (O33921    ), 
PHO10_CAEEL (Q09448    ), PHO11_CAEEL (Q09451    ), PHO5_CAEEL  (Q10944    ), 
PHYA1_ASPTE (O00085    ), PHYA2_ASPTE (O00100    ), PHYA_ARTBC  (D4ANW6    ), 
PHYA_ASPAW  (P34753    ), PHYA_ASPFU  (O00092    ), PHYA_ASPNG  (P34752    ), 
PHYA_ASPOR  (Q9C1T1    ), PHYA_ASPTN  (Q0CLV1    ), PHYA_THIHE  (O00107    ), 
PHYB_ASPAW  (P34755    ), PHYB_ASPNG  (P34754    ), PHYB_EMENI  (O00093    ), 
PPA1_PICPA  (P52291    ), PPA1_SCHPO  (P08091    ), PPA2_SCHPO  (Q01682    ), 
PPA3_SCHPO  (O60172    ), PPA3_YEAST  (P24031    ), PPA5_KLULA  (P52289    ), 
PPA5_YEAST  (P00635    ), PPAB_YEAST  (P35842    ), PPAC_YEAST  (P38693    ), 
PPAD_YEAST  (P52290    ), PPAL_BOVIN  (Q0P5F0    ), PPAL_HUMAN  (P11117    ), 
PPAL_MACFA  (Q4R5N9    ), PPAL_MOUSE  (P24638    ), PPAL_PONAB  (Q5NVF6    ), 
PPAL_RAT    (P20611    ), PPAL_XENLA  (B1H1P9    ), PPAP_BOVIN  (A6H730    ), 
PPAP_HUMAN  (P15309    ), PPAP_MOUSE  (Q8CE08    ), PPAT_HUMAN  (Q9BZG2    ), 
PPAT_MOUSE  (D3YTS9    ), PPAT_XENLA  (Q3KQG9    ), PPAX_CAEEL  (Q09549    ), 
PPA_ECOLI   (P07102    ), STPA_SYNY3  (Q55034    ), Y4755_DICDI (Q54P71    )
» more

UniProtKB/Swiss-Prot
False negative sequences
32 sequences

ACP1_CAEBR  (Q619N4    ), ACP1_CAEEL  (Q23534    ), ACPH1_APIME (Q5BLY5    ), 
CF60_DICDI  (Q54PR9    ), PEPP_ALLCE  (Q93WP4    ), PHO1_CAEEL  (Q19076    ), 
PPA4_SCHPO  (Q9USS6    ), PPA6_BOVIN  (A6H757    ), PPA6_HUMAN  (Q9NPH0    ), 
PPA6_MOUSE  (Q8BP40    ), PPA6_PONAB  (Q5R8C0    ), PPAP_RAT    (P20646    ), 
PXYP1_DANRE (Q6DH46    ), PXYP1_HUMAN (Q8TE99    ), PXYP1_MOUSE (Q8BHA9    ), 
PXYP1_RAT   (Q66H78    ), PXYP1_XENTR (Q0IHQ9    ), VIP1L_ARATH (F4J8C6    ), 
VIP1_BOVIN  (A7Z050    ), VIP1_CAEEL  (P91309    ), VIP1_DROME  (Q9VR59    ), 
VIP1_HUMAN  (Q6PFW1    ), VIP1_MOUSE  (A2ARP1    ), VIP1_PONAB  (Q5RDF1    ), 
VIP1_RAT    (P0C644    ), VIP1_SCHPO  (O74429    ), VIP1_YEAST  (Q06685    ), 
VIP2_HUMAN  (O43314    ), VIP2_MOUSE  (Q6ZQB6    ), VIP2_PONAB  (Q5REW0    ), 
VIP2_XENLA  (Q5XHF8    ), Y4753_DICDI (Q54P72    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

PHYB_ASPFI  (P81440    )

		
UniProtKB/Swiss-Prot
False positive sequences
43 sequences

ARGB_CHLPM  (A4SEI5    ), AT18C_ARATH (Q8GYD7    ), AT18D_ARATH (Q0WPK3    ), 
AT18E_ARATH (Q9FHK8    ), CTX80_EUPOC (Q9N9X3    ), DBF4A_CRIGR (Q99MU0    ), 
DBP9_USTMA  (Q4P7M1    ), DPOL_SFAVA  (Q779J8    ), DTPA_CROTZ  (C9Y3M8    ), 
DTPA_ECO57  (Q8X651    ), DTPA_ECOL6  (Q8FH91    ), DTPA_ECOLI  (P77304    ), 
DTPA_ENT38  (A4W9W3    ), DTPA_KLEP3  (B5XWP3    ), DTPA_SALTI  (Q8Z6Q5    ), 
DTPA_SALTY  (Q8ZPM6    ), DTX18_ARATH (Q9LUH3    ), EMAL1_HUMAN (O00423    ), 
EMAL1_MOUSE (Q05BC3    ), EMAL1_RAT   (Q4V8C3    ), EMAL4_HUMAN (Q9HC35    ), 
EMAL4_XENLA (Q2TAF3    ), EMAL4_XENTR (Q6DIP5    ), EMAP_STRPU  (Q26613    ), 
GBB3_CANLF  (P79147    ), GBB3_HUMAN  (P16520    ), GBB3_MOUSE  (Q61011    ), 
GBB3_RAT    (P52287    ), INT_BACSU   (P96629    ), LRC40_DANRE (Q7SXW3    ), 
LRC40_HUMAN (Q9H9A6    ), LRC40_MACFA (Q4R3P6    ), LRC40_MOUSE (Q9CRC8    ), 
LRC40_PONAB (Q5RFE9    ), LRC40_XENLA (Q6GPJ5    ), LRC40_XENTR (Q5M8G4    ), 
L_MABVO     (Q6UY63    ), NBEL2_DANRE (E7FAW3    ), SURE1_BURL3 (Q390V3    ), 
TRKH_HALED  (E1V6C5    ), VIRB5_AGRFC (P17795    ), VIRB5_AGRT9 (P0A3W3    ), 
VIRB5_RHIRD (P0A3W2    )
» more

PDB
[Detailed view]
23 PDB

1CVI; 1DKL; 1DKM; 1DKN; 1DKO; 1DKP; 1DKQ; 1IHP; 1ND5; 1ND6; 1NT4; 1QFX; 1QWO; 1RPA; 1RPT; 1SK8; 1SK9; 1SKA; 1SKB; 2HPA; 3K4P; 3K4Q; 4TSR
» more

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