Entry: PS00778

General information about the entry
Entry name HIS_ACID_PHOSPHAT_2
Accession number PS00778
Entry type PATTERN
Date DEC-1992 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00538
Name and characterization of the entry
DescriptionHistidine acid phosphatases active site signature.
Pattern [LIVMF]-x-[LIVMFAG]-{T}-x-[STAGI]-H-D-[STANQ]-{V}-[LIVM]-x(2)-[LIVMFY]- x(2)-[STA].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 85 hits in 85 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 43 hits in 43 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 42 hits in 42 different sequences
  • Number of known missed hits: 29
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 50.59 %
  • Recall (true hits / (true hits + false negatives)): 59.72 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 7,active_site
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
AGP_ECOLI   (P19926), AGP_PRORE   (Q52309), AGP_SALTY   (O33921), 
PHO10_CAEEL (Q09448), PHO11_CAEEL (Q09451), PHO5_CAEEL  (Q10944), 
PHYA1_ASPTE (O00085), PHYA2_ASPTE (O00100), PHYA_ASPAW  (P34753), 
PHYA_ASPFU  (O00092), PHYA_ASPNG  (P34752), PHYA_ASPOR  (Q9C1T1), 
PHYA_ASPTN  (Q0CLV1), PHYA_THIHE  (O00107), PHYB_ASPAW  (P34755), 
PHYB_ASPNG  (P34754), PHYB_EMENI  (O00093), PPA1_PICPA  (P52291), 
PPA1_SCHPO  (P08091), PPA2_SCHPO  (Q01682), PPA3_SCHPO  (O60172), 
PPA3_YEAST  (P24031), PPA5_KLULA  (P52289), PPA5_YEAST  (P00635), 
PPAB_YEAST  (P35842), PPAC_YEAST  (P38693), PPAD_YEAST  (P52290), 
PPAL_BOVIN  (Q0P5F0), PPAL_HUMAN  (P11117), PPAL_MACFA  (Q4R5N9), 
PPAL_MOUSE  (P24638), PPAL_PONAB  (Q5NVF6), PPAL_RAT    (P20611), 
PPAL_XENLA  (B1H1P9), PPAP_BOVIN  (A6H730), PPAP_HUMAN  (P15309), 
PPAP_MOUSE  (Q8CE08), PPAT_HUMAN  (Q9BZG2), PPAT_XENLA  (Q3KQG9), 
PPAX_CAEEL  (Q09549), PPA_ECOLI   (P07102), STPA_SYNY3  (Q55034), 
Y4755_DICDI (Q54P71)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
ACP1_CAEBR  (Q619N4), ACP1_CAEEL  (Q23534), ACPH1_APIME (Q5BLY5), 
ACPL2_DANRE (Q6DH46), ACPL2_HUMAN (Q8TE99), ACPL2_MOUSE (Q8BHA9), 
ACPL2_RAT   (Q66H78), ACPL2_XENTR (Q0IHQ9), CF60_DICDI  (Q54PR9), 
PEPP_ALLCE  (Q93WP4), PPA4_SCHPO  (Q9USS6), PPA6_HUMAN  (Q9NPH0), 
PPA6_MOUSE  (Q8BP40), PPA6_PONAB  (Q5R8C0), PPAP_RAT    (P20646), 
VIP1_BOVIN  (A7Z050), VIP1_CAEEL  (P91309), VIP1_DROME  (Q9VR59), 
VIP1_HUMAN  (Q6PFW1), VIP1_MOUSE  (A2ARP1), VIP1_PONAB  (Q5RDF1), 
VIP1_RAT    (P0C644), VIP1_SCHPO  (O74429), VIP1_YEAST  (Q06685), 
VIP2_HUMAN  (O43314), VIP2_MOUSE  (Q6ZQB6), VIP2_PONAB  (Q5REW0), 
VIP2_XENLA  (Q5XHF8), Y4753_DICDI (Q54P72)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
PHYB_ASPFI  (P81440)
False positive hits (sequences which do not belong to the set under consideration):
ARGB_PROVI  (A4SEI5), AT18C_ARATH (Q8GYD7), AT18D_ARATH (Q0WPK3), 
AT18E_ARATH (Q9FHK8), CTX80_EUPOC (Q9N9X3), DBF4A_CRIGR (Q99MU0), 
DBP9_USTMA  (Q4P7M1), DPOL_SFAVA  (Q779J8), DTPA_CROTZ  (C9Y3M8), 
DTPA_ECO57  (Q8X651), DTPA_ECOL6  (Q8FH91), DTPA_ECOLI  (P77304), 
DTPA_ENT38  (A4W9W3), DTPA_KLEP3  (B5XWP3), DTPA_SALTI  (Q8Z6Q5), 
DTPA_SALTY  (Q8ZPM6), EMAL1_HUMAN (O00423), EMAL1_MOUSE (Q05BC3), 
EMAL1_RAT   (Q4V8C3), EMAL4_HUMAN (Q9HC35), EMAL4_XENLA (Q2TAF3), 
EMAL4_XENTR (Q6DIP5), EMAP_STRPU  (Q26613), GBB3_CANFA  (P79147), 
GBB3_HUMAN  (P16520), GBB3_MOUSE  (Q61011), GBB3_RAT    (P52287), 
INT_BACSU   (P96629), LAL5_ARATH  (Q9LUH3), LRC40_DANRE (Q7SXW3), 
LRC40_HUMAN (Q9H9A6), LRC40_MACFA (Q4R3P6), LRC40_MOUSE (Q9CRC8), 
LRC40_PONAB (Q5RFE9), LRC40_XENLA (Q6GPJ5), LRC40_XENTR (Q5M8G4), 
L_MABVO     (Q6UY63), NBEL2_DANRE (E7FAW3), SURE1_BURS3 (Q390V3), 
VIRB5_AGRT5 (P17795), VIRB5_AGRT9 (P0A3W3), VIRB5_RHIRD (P0A3W2)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

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PDB
[Detailed view]		 1CVI; 1DKL; 1DKM; 1DKN; 1DKO; 1DKP; 1DKQ; 1IHP; 1ND5; 1ND6; 1NT4; 1QFX; 1QWO; 1RPA; 1RPT; 1SK8; 1SK9; 1SKA; 1SKB; 2HPA; 3K4P; 3K4Q;

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