Entry: PS00778

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General information about the entry

Entry name [info] HIS_ACID_PHOSPHAT_2
Accession [info] PS00778
Entry type [info] PATTERN
Date [info] DEC-1992 (CREATED); APR-2006 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00538

Name and characterization of the entry

Description [info] Histidine acid phosphatases active site signature.
Pattern [info]
[LIVMF]-x-[LIVMFAG]-{T}-x-[STAGI]-H-D-[STANQ]-{V}-[LIVM]-x(2)-[LIVMFY]-
x(2)-[STA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 85 in 85 different sequences
Number of true positive hits 43 in 43 different sequences
Number of 'unknown' hits
Number of false positive hits 42 in 42 different sequences
Number of false negative sequences 30
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 50.59 %
Recall (true positives / (true positives + false negatives)) 58.90 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
43 sequences

AGP_ECOLI   (P19926), AGP_PRORE   (Q52309), AGP_SALTY   (O33921), 
PHO10_CAEEL (Q09448), PHO11_CAEEL (Q09451), PHO5_CAEEL  (Q10944), 
PHYA1_ASPTE (O00085), PHYA2_ASPTE (O00100), PHYA_ASPAW  (P34753), 
PHYA_ASPFU  (O00092), PHYA_ASPNG  (P34752), PHYA_ASPOR  (Q9C1T1), 
PHYA_ASPTN  (Q0CLV1), PHYA_THIHE  (O00107), PHYB_ASPAW  (P34755), 
PHYB_ASPNG  (P34754), PHYB_EMENI  (O00093), PPA1_PICPA  (P52291), 
PPA1_SCHPO  (P08091), PPA2_SCHPO  (Q01682), PPA3_SCHPO  (O60172), 
PPA3_YEAST  (P24031), PPA5_KLULA  (P52289), PPA5_YEAST  (P00635), 
PPAB_YEAST  (P35842), PPAC_YEAST  (P38693), PPAD_YEAST  (P52290), 
PPAL_BOVIN  (Q0P5F0), PPAL_HUMAN  (P11117), PPAL_MACFA  (Q4R5N9), 
PPAL_MOUSE  (P24638), PPAL_PONAB  (Q5NVF6), PPAL_RAT    (P20611), 
PPAL_XENLA  (B1H1P9), PPAP_BOVIN  (A6H730), PPAP_HUMAN  (P15309), 
PPAP_MOUSE  (Q8CE08), PPAT_HUMAN  (Q9BZG2), PPAT_XENLA  (Q3KQG9), 
PPAX_CAEEL  (Q09549), PPA_ECOLI   (P07102), STPA_SYNY3  (Q55034), 
Y4755_DICDI (Q54P71)
» More

UniProtKB/Swiss-Prot
False negative sequences
30 sequences

ACP1_CAEBR  (Q619N4), ACP1_CAEEL  (Q23534), ACPH1_APIME (Q5BLY5), 
ACPL2_DANRE (Q6DH46), ACPL2_HUMAN (Q8TE99), ACPL2_MOUSE (Q8BHA9), 
ACPL2_RAT   (Q66H78), ACPL2_XENTR (Q0IHQ9), CF60_DICDI  (Q54PR9), 
PEPP_ALLCE  (Q93WP4), PPA4_SCHPO  (Q9USS6), PPA6_BOVIN  (A6H757), 
PPA6_HUMAN  (Q9NPH0), PPA6_MOUSE  (Q8BP40), PPA6_PONAB  (Q5R8C0), 
PPAP_RAT    (P20646), VIP1_BOVIN  (A7Z050), VIP1_CAEEL  (P91309), 
VIP1_DROME  (Q9VR59), VIP1_HUMAN  (Q6PFW1), VIP1_MOUSE  (A2ARP1), 
VIP1_PONAB  (Q5RDF1), VIP1_RAT    (P0C644), VIP1_SCHPO  (O74429), 
VIP1_YEAST  (Q06685), VIP2_HUMAN  (O43314), VIP2_MOUSE  (Q6ZQB6), 
VIP2_PONAB  (Q5REW0), VIP2_XENLA  (Q5XHF8), Y4753_DICDI (Q54P72)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

PHYB_ASPFI  (P81440)

		
UniProtKB/Swiss-Prot
False positive sequences
42 sequences

ARGB_PROVI  (A4SEI5), AT18C_ARATH (Q8GYD7), AT18D_ARATH (Q0WPK3), 
AT18E_ARATH (Q9FHK8), CTX80_EUPOC (Q9N9X3), DBF4A_CRIGR (Q99MU0), 
DBP9_USTMA  (Q4P7M1), DPOL_SFAVA  (Q779J8), DTPA_CROTZ  (C9Y3M8), 
DTPA_ECO57  (Q8X651), DTPA_ECOL6  (Q8FH91), DTPA_ECOLI  (P77304), 
DTPA_ENT38  (A4W9W3), DTPA_KLEP3  (B5XWP3), DTPA_SALTI  (Q8Z6Q5), 
DTPA_SALTY  (Q8ZPM6), EMAL1_HUMAN (O00423), EMAL1_MOUSE (Q05BC3), 
EMAL1_RAT   (Q4V8C3), EMAL4_HUMAN (Q9HC35), EMAL4_XENLA (Q2TAF3), 
EMAL4_XENTR (Q6DIP5), EMAP_STRPU  (Q26613), GBB3_CANFA  (P79147), 
GBB3_HUMAN  (P16520), GBB3_MOUSE  (Q61011), GBB3_RAT    (P52287), 
INT_BACSU   (P96629), LAL5_ARATH  (Q9LUH3), LRC40_DANRE (Q7SXW3), 
LRC40_HUMAN (Q9H9A6), LRC40_MACFA (Q4R3P6), LRC40_MOUSE (Q9CRC8), 
LRC40_PONAB (Q5RFE9), LRC40_XENLA (Q6GPJ5), LRC40_XENTR (Q5M8G4), 
L_MABVO     (Q6UY63), NBEL2_DANRE (E7FAW3), SURE1_BURS3 (Q390V3), 
VIRB5_AGRT5 (P17795), VIRB5_AGRT9 (P0A3W3), VIRB5_RHIRD (P0A3W2)
» More

PDB
[Detailed view]
22 PDB

1CVI; 1DKL; 1DKM; 1DKN; 1DKO; 1DKP; 1DKQ; 1IHP; 1ND5; 1ND6; 1NT4; 1QFX; 1QWO; 1RPA; 1RPT; 1SK8; 1SK9; 1SKA; 1SKB; 2HPA; 3K4P; 3K4Q
» More

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