PROSITE entry PS00914

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General information about the entry

Entry name [info]	SYNTAXIN
Accession [info]	PS00914
Entry type [info]	PATTERN
Date [info]	01-OCT-1993 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00709

Name and characterization of the entry

Description [info]

Syntaxin / epimorphin family signature.

Pattern [info]

[RQLKA]-x(3)-[LIVMAW]-x(2)-[LIVM]-[ESHLKAGQV]-x(2)-[LIVMT]-x-[DEVMNRAST]-
[LIVMT]-x(2)-[LIVMQ]-[FSAQGVM]-x(2)-[LIVMF]-x(3)-[LIVT]-x(2)-Q-
[GADEQVST]-x(2)-[LIVMA]-[DNQTEI]-x-[LIVMF]-[DESVHAG]-x(2,3)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.

Total number of hits	103 in 103 different sequences
Number of true positive hits	103 in 103 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	14
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	88.03 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

103 sequences

PEP12_YEAST (P32854), PSY1_SCHPO  (Q9USH7), SED5_YEAST  (Q01590),

SSO1_YEAST  (P32867), SSO2_CANAL  (Q59YF0), SSO2_YEAST  (P39926), 
STX10_HUMAN (O60499), STX11_HUMAN (O75558), STX11_MOUSE (Q9D3G5), 
STX12_HUMAN (Q86Y82), STX12_MOUSE (Q9ER00), STX12_PONAB (Q5RBW6), 
STX12_RAT   (G3V7P1), STX16_HUMAN (O14662), STX16_MOUSE (Q8BVI5), 
STX17_BOVIN (Q5E9Y2), STX17_HUMAN (P56962), STX17_MOUSE (Q9D0I4), 
STX17_RAT   (Q9Z158), STX18_DANRE (Q4VBI7), STX18_HUMAN (Q9P2W9), 
STX18_MOUSE (Q8VDS8), STX18_PONAB (Q5REB4), STX18_RAT   (Q68FW4), 
STX19_BOVIN (Q0VCI2), STX19_HUMAN (Q8N4C7), STX19_MOUSE (Q8R1Q0), 
STX19_PONAB (Q5RAL4), STX1A_ANOGA (Q5TX47), STX1A_BOVIN (P32850), 
STX1A_CAEBR (A8WVD0), STX1A_CAEEL (O16000), STX1A_DROME (Q24547), 
STX1A_HUMAN (Q16623), STX1A_MOUSE (O35526), STX1A_PONAB (Q5R4L2), 
STX1A_RAT   (P32851), STX1B_BOVIN (P61267), STX1B_HUMAN (P61266), 
STX1B_MOUSE (P61264), STX1B_RAT   (P61265), STX1B_SHEEP (P61268), 
STX2_CAEEL  (Q20574), STX2_HUMAN  (P32856), STX2_MOUSE  (Q00262), 
STX2_RAT(P50279), STX3_CAEEL  (Q20024), STX3_HUMAN  (Q13277), 
STX3_MOUSE  (Q64704), STX3_RAT(Q08849), STX4_BOVIN  (Q3SWZ3), 
STX4_CAEEL  (P91409), STX4_HUMAN  (Q12846), STX4_MOUSE  (P70452), 
STX4_RAT(Q08850), STX5_BOVIN  (Q08DB5), STX5_CAEEL  (Q20797), 
STX5_DROME  (Q24509), STX5_HUMAN  (Q13190), STX5_MOUSE  (Q8K1E0), 
STX5_RAT(Q08851), STX6_CAEEL  (P83528), STX6_CHICK  (Q5ZL19), 
STX6_HUMAN  (O43752), STX6_MOUSE  (Q9JKK1), STX6_PONAB  (Q5R6Q2), 
STX6_RAT(Q63635), STX7A_DICDI (Q54JY7), STX7_BOVIN  (Q3ZBT5), 
STX7_HUMAN  (O15400), STX7_MOUSE  (O70439), STX7_PONAB  (Q5R602), 
STX7_RAT(O70257), STX_APLCA   (Q16932), SY111_ARATH (Q42374), 
SY111_ORYSJ (Q84R43), SY112_ARATH (Q9ZPV9), SY121_ARATH (Q9ZSD4), 
SY121_ORYSJ (Q6F3B4), SY122_ARATH (Q9SVC2), SY123_ARATH (Q9ZQZ8), 
SY124_ARATH (O64791), SY125_ARATH (Q9SXB0), SY131_ARATH (Q9SRV7), 
SY132_ARATH (Q8VZU2), SY132_ORYSJ (Q7XIE2), SYP21_ARATH (Q39233), 
SYP22_ARATH (P93654), SYP23_ARATH (O04378), SYP31_ARATH (Q9FFK1), 
SYP32_ARATH (Q9LK09), SYP41_ARATH (O65359), SYP42_ARATH (Q9SWH4), 
SYP43_ARATH (Q9SUJ1), SYP51_ARATH (Q9SA23), SYP52_ARATH (Q94KK7), 
SYP61_ARATH (Q946Y7), SYP71_ARATH (Q9SF29), SYP72_ARATH (Q94KK6), 
SYP73_ARATH (Q94KK5), TLG1_YEAST  (Q03322), TLG2_YEAST  (Q08144), 
VAM3_YEAST  (Q12241)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

14 sequences

FSV1_SCHPO  (O14222), PEP12_SCHPO (O94651), SED5_SCHPO  (O13644),

STX8A_DICDI (Q553P5), STX8_BOVIN  (Q3T075), STX8_HUMAN  (Q9UNK0), 
STX8_MOUSE  (O88983), STX8_RAT(Q9Z2Q7), SYP24_ARATH (Q9C615), 
SYP81_ARATH (P59277), TLG1_SCHPO  (Q9HGN3), TLG2_SCHPO  (Q9P6P1), 
UFE1_SCHPO  (O94531), UFE1_YEAST  (P41834)

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PDB
[Detailed view]

38 PDB

1GL2; 1HVV; 1JTH; 1KIL; 1N7S; 1SFC; 1URQ; 2M8R; 2N1T; 2NPS; 3B5N; 3C98; 3HD7; 3IPD; 3J96; 3J97; 3J98; 3J99; 3RK2; 3RK3; 3RL0; 4JEH; 4JEU; 5CCG; 5CCH; 5CCI; 5KJ7; 5KJ8; 5W5C; 5W5D; 6IP1; 6MDM; 6MDN; 6MTI; 6WVW; 7BV6; 7Q83; 7XSJ
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