Entry: PS01047

General information about the entry

Entry name [info] HMA_1
Accession [info] PS01047
Entry type [info] PATTERN
Date [info] NOV-1995 (CREATED); APR-2006 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00804

Name and characterization of the entry

Description [info] Heavy-metal-associated domain.
Pattern [info]
[LIVNS]-x-{L}-[LIVMFA]-x-C-x-[STAGCDNH]-C-x(3)-[LIVFG]-{LV}-x(2)-[LIV]-
x(9,11)-[IVA]-x-[LVFYS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 211 in 144 different sequences
Number of true positive hits 198 in 131 different sequences
Number of 'unknown' hits 0
Number of false positive hits 13 in 13 different sequences
Number of false negative sequences 22
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 93.84 %
Recall (true positives / (true positives + false negatives)) 90.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 6
Site [info] metal(?) at position 6
Site [info] metal(?) at position 9
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
131 sequences

ATCS_SYNE7  (P37279), ATCS_SYNY3  (P73241), ATCU1_RHIME (P58341), 
ATCU2_RHIME (P58342), ATCU_SINMW  (Q9X5X3), ATOX1_BOVIN (Q3T0E0), 
ATOX1_CANFA (Q9TT99), ATOX1_HUMAN (O00244), ATOX1_MOUSE (O08997), 
ATOX1_RAT   (Q9WUC4), ATOX1_SHEEP (Q9XT28), ATP7A_CRIGR (P49015), 
ATP7A_HUMAN (Q04656), ATP7A_MOUSE (Q64430), ATP7A_RAT   (P70705), 
ATP7B_HUMAN (P35670), ATP7B_MOUSE (Q64446), ATP7B_RAT   (Q64535), 
ATP7B_SHEEP (Q9XT50), ATSY_SYNE7  (P37385), ATSY_SYNP6  (P07893), 
ATU2_SCHPO  (O59666), ATU2_YEAST  (P38995), ATX1_SCHPO  (O74735), 
ATX1_YEAST  (P38636), ATZN_ECOLI  (P37617), ATZN_SYNY3  (Q59998), 
CADA1_STAAU (P20021), CADA2_STAAU (P37386), CADA_BACPE  (P30336), 
CADA_BACSU  (O32219), CADA_LISMN  (Q60048), CADA_LISMO  (P58414), 
CADA_STAAR  (Q6GIX1), COPA1_HELPX (P77871), COPA2_HELPX (Q59467), 
COPA3_HELPX (O08462), COPA_ARCFU  (O29777), COPA_BACSU  (O32220), 
COPA_ECO57  (Q8XD24), COPA_ECOLI  (Q59385), COPA_ENTHA  (P32113), 
COPA_HELFC  (O32619), COPA_HELPJ  (Q9ZM69), COPA_HELPY  (P55989), 
COPA_SALTI  (Q8Z8S4), COPA_SALTY  (Q8ZR95), COPA_STAA1  (A7X6S1), 
COPA_STAA2  (A6U4T8), COPA_STAA3  (Q2FDV0), COPA_STAA8  (Q2FV64), 
COPA_STAA9  (A5IVY3), COPA_STAAB  (Q2YWA3), COPA_STAAC  (Q5HCZ3), 
COPA_STAAE  (A6QK47), COPA_STAAM  (Q99R80), COPA_STAAN  (Q7A3E6), 
COPA_STAAR  (Q6GDP1), COPA_STAAS  (Q6G6B7), COPA_STAAT  (A8Z3F8), 
COPA_STAAW  (Q8NUQ9), COPA_STAEQ  (Q5HL56), COPA_STAES  (Q8CN02), 
COPA_STAHJ  (Q4L970), COPA_STAS1  (Q4A0G1), COPA_VIBCH  (Q9KPZ7), 
COPA_YERPE  (Q8ZCA7), COPP_HELFC  (O32620), COPP_HELPJ  (Q9ZM70), 
COPP_HELPY  (Q48271), COPZ_ARCFU  (O29901), COPZ_BACSU  (O32221), 
COPZ_ENTHA  (Q47840), COPZ_STAA1  (A7X6S3), COPZ_STAA2  (A6U4T9), 
COPZ_STAA3  (Q2FDU9), COPZ_STAA8  (Q2FV63), COPZ_STAA9  (A5IVY4), 
COPZ_STAAB  (P0C885), COPZ_STAAC  (Q5HCZ2), COPZ_STAAE  (A6QK48), 
COPZ_STAAM  (Q99R79), COPZ_STAAN  (Q7A3E5), COPZ_STAAR  (Q6GDP0), 
COPZ_STAAS  (Q6G6B6), COPZ_STAAT  (A8Z3F9), COPZ_STAAW  (Q79ZY4), 
COPZ_STAEQ  (Q5HL55), COPZ_STAES  (Q8CN01), COPZ_STAHJ  (Q4L971), 
COPZ_STAS1  (Q4A0G2), CTPA_MYCLE  (P46839), CTPA_MYCTO  (P9WPU0), 
CTPA_MYCTU  (P9WPU1), CTPB_MYCBO  (P59947), CTPB_MYCLE  (P46840), 
CTPB_MYCTO  (P9WPT8), CTPB_MYCTU  (P9WPT9), FIXI_BRADU  (Q59207), 
FIXI_RHILV  (O33533), FIXI_RHIME  (P18398), HMA5_ARATH  (Q9SH30), 
HMA6_ARATH  (Q9SZC9), HMA7_ARATH  (Q9S7J8), HMCT_HELPJ  (Q9ZL53), 
HMCT_HELPY  (Q59465), MERA_ACICA  (Q52109), MERA_ACIFR  (P17239), 
MERA_ALCSP  (P94188), MERA_BACCE  (P16171), MERA_ENTAG  (P94702), 
MERA_PSEAI  (P00392), MERA_PSEFL  (Q51772), MERA_SERMA  (P08662), 
MERA_SHEPU  (Q54465), MERA_SHIFL  (P08332), MERA_STAAU  (P0A0E5), 
MERA_STAES  (P0A0E4), MERP_ACICA  (Q52107), MERP_ALCSP  (P94186), 
MERP_ENTAG  (P0A217), MERP_ENTCL  (P0A218), MERP_PSEAI  (P04131), 
MERP_PSEFL  (Q51770), MERP_SALTI  (P0A216), MERP_SERMA  (P13113), 
MERP_SHEPU  (Q54463), MERP_SHIFL  (P04129), Y290_HAEIN  (P77868), 
Y291_HAEIN  (P43979), Y292_HAEIN  (O32622)
» More

UniProtKB/Swiss-Prot
False negative sequences
22 sequences

ATOX1_ARATH (Q94BT9), ATOX1_DICDI (Q54PZ2), ATU1_YEAST  (P38360), 
CCH_ARATH   (O82089), CCS1_ASHGO  (Q75DD6), CCS1_CANGA  (Q6FU61), 
CCS1_DEBHA  (Q6BK66), CCS1_KLULA  (Q6CIG2), CCS1_YARLI  (Q6BZU2), 
CCS1_YEAST  (P40202), CCS_ARATH   (Q9LD47), CCS_DICDI   (Q54F73), 
CCS_HUMAN   (O14618), CCS_MOUSE   (Q9WU84), CCS_ORYSJ   (Q7XTY9), 
CCS_RAT     (Q9JK72), HIP26_ARATH (Q9SZN7), HMA2_ARATH  (Q9SZW4), 
HMA3A_ARATH (P0CW77), HMA3B_ARATH (P0CW78), HMA4_ARATH  (O64474), 
HMCT_HELFE  (Q9RQB4)
» More

UniProtKB/Swiss-Prot
False positive sequences
13 sequences

CG013_HUMAN (Q8NI28), CSPL7_ORYSJ (Q6YT98), CYC6_ARTMA  (P00118), 
CYC6_GRATL  (Q6B941), CYC6_MICAE  (P00112), GPI7_YEAST  (P40367), 
HMGB7_ARATH (Q8LDF9), NU5C_NEPOL  (Q9TKV7), RECO_LEIXX  (Q6AED5), 
SYFA_THEFY  (Q47N75), UD2A3_HUMAN (Q6UWM9), UD2A3_PONAB (Q5RFJ3), 
YAB4_ARATH  (Q9LDT3)
» More

PDB
[Detailed view]
70 PDB

1AFI; 1AFJ; 1AW0; 1CC7; 1CC8; 1CPZ; 1FD8; 1FE0; 1FE4; 1FEE; 1FES; 1FVQ; 1FVS; 1JWW; 1K0V; 1KQK; 1KVI; 1KVJ; 1MWY; 1MWZ; 1OPZ; 1OQ3; 1OQ6; 1P6T; 1P8G; 1Q8L; 1S6O; 1S6U; 1TL4; 1TL5; 1Y3J; 1Y3K; 1YG0; 1YJR; 1YJT; 1YJU; 1YJV; 2AJ0; 2AJ1; 2AW0; 2EW9; 2G9O; 2GA7; 2GCF; 2GGP; 2HQI; 2K1R; 2KT2; 2KT3; 2LDI; 2LQ9; 2LQB; 2OFG; 2OFH; 2QIF; 2RML; 2ROP; 2VOY; 2XMW; 3CJK; 3DXS; 3FRY; 3I9Z; 3IWL; 3IWX; 3K7R; 4A48; 4A4J; 4YDX; 4YEA
» More

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