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Entry: PS01070

General information about the entry

Entry name [info] NUCLEASE_NON_SPEC
Accession [info] PS01070
Entry type [info] PATTERN
Date [info] 01-NOV-1995 CREATED; 01-JUL-1999 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00821
Associated ProRule [info] PRU10047

Name and characterization of the entry

Description [info] DNA/RNA non-specific endonucleases active site.
Pattern [info]
D-R-G-H-[QLIM]-x(3)-[AG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 16 in 16 different sequences
Number of true positive hits 12 in 12 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 75.00 %
Recall (true positives / (true positives + false negatives)) 92.31 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
12 sequences

NUC1_CUNEE  (P81203    ), NUC1_SYNRA  (P81204    ), NUC1_YEAST  (P08466    ), 
NUCA_NOSS1  (P38446    ), NUCA_SERMA  (P13717    ), NUCE_STRPN  (P0A3S3    ), 
NUCE_STRR6  (P0A3S4    ), NUCG_BOVIN  (P38447    ), NUCG_CAEEL  (Q95NM6    ), 
NUCG_HUMAN  (Q14249    ), NUCG_MOUSE  (O08600    ), PNU1_SCHPO  (Q10480    )
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

EXOG_HUMAN  (Q9Y2C4    )

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

FHCA_METEA  (C5B137    ), MURD_PSEPF  (Q3K742    ), TGA6_ARATH  (Q39140    ), 
Y4XK_SINFN  (P55703    )
» more

PDB
[Detailed view]
7 PDB

1G8T; 1QAE; 1QL0; 1SMN; 3S5B; 4E3Y; 4QN0

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