Entry: PS01070

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General information about the entry

Entry name [info] NUCLEASE_NON_SPEC
Accession [info] PS01070
Entry type [info] PATTERN
Date [info] NOV-1995 (CREATED); JUL-1999 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00821
Associated ProRule [info] PRU10047

Name and characterization of the entry

Description [info] DNA/RNA non-specific endonucleases active site.
Pattern [info]
D-R-G-H-[QLIM]-x(3)-[AG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 16 in 16 different sequences
Number of true positive hits 12 in 12 different sequences
Number of 'unknown' hits
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 75.00 %
Recall (true positives / (true positives + false negatives)) 92.31 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
12 sequences

NUC1_CUNEE  (P81203), NUC1_SYNRA  (P81204), NUC1_YEAST  (P08466), 
NUCA_NOSS1  (P38446), NUCA_SERMA  (P13717), NUCE_STRPN  (P0A3S3), 
NUCE_STRR6  (P0A3S4), NUCG_BOVIN  (P38447), NUCG_CAEEL  (Q95NM6), 
NUCG_HUMAN  (Q14249), NUCG_MOUSE  (O08600), PNU1_SCHPO  (Q10480)
» More

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

EXOG_HUMAN  (Q9Y2C4)

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

FHCA_METEA  (C5B137), MURD_PSEPF  (Q3K742), TGA6_ARATH  (Q39140), 
Y4XK_RHISN  (P55703)
» More

PDB
[Detailed view]
6 PDB

1G8T; 1QAE; 1QL0; 1SMN; 3S5B; 4E3Y

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