Entry: PS01070

General information about the entry

Entry name [info] NUCLEASE_NON_SPEC
Accession [info] PS01070
Entry type [info] PATTERN
Date [info] NOV-1995 (CREATED); JUL-1999 (DATA UPDATE); MAY-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00821
Associated ProRule [info] PRU10047

Name and characterization of the entry

Description [info] DNA/RNA non-specific endonucleases active site.
Pattern [info]
D-R-G-H-[QLIM]-x(3)-[AG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_07 which contains 548'872 sequence entries.


Total number of hits 16 in 16 different sequences
Number of true positive hits 12 in 12 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 75.00 %
Recall (true positives / (true positives + false negatives)) 92.31 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
12 sequences

NUC1_CUNEE  (P81203), NUC1_SYNRA  (P81204), NUC1_YEAST  (P08466), 
NUCA_NOSS1  (P38446), NUCA_SERMA  (P13717), NUCE_STRPN  (P0A3S3), 
NUCE_STRR6  (P0A3S4), NUCG_BOVIN  (P38447), NUCG_CAEEL  (Q95NM6), 
NUCG_HUMAN  (Q14249), NUCG_MOUSE  (O08600), PNU1_SCHPO  (Q10480)
» More

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

EXOG_HUMAN  (Q9Y2C4)

		
UniProtKB/Swiss-Prot
False positive sequences
4 sequences

FHCA_METEA  (C5B137), MURD_PSEPF  (Q3K742), TGA6_ARATH  (Q39140), 
Y4XK_RHISN  (P55703)
» More

PDB
[Detailed view]
6 PDB

1G8T; 1QAE; 1QL0; 1SMN; 3S5B; 4E3Y

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