Entry: PS01173

General information about the entry
Entry name LIPASE_GDXG_HIS
Accession number PS01173
Entry type PATTERN
Date NOV-1997 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00903
Name and characterization of the entry
DescriptionLipolytic enzymes "G-D-X-G" family, putative histidine active site.
Pattern [LIVMF](2)-x-[LIVMF]-H-G-G-[SAG]-[FYW]-x(3)-[STDN]-x(1,2)-[STYA]-[HAGFT].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 45 hits in 45 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 45 hits in 45 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 37
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 54.88 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 4,active_site(?)
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
AAAD_MOUSE  (Q99PG0), AAAD_RAT    (Q9QZH8), AES_ECO24   (A7ZIN6), 
AES_ECO27   (B7UKF6), AES_ECO45   (B7MDZ8), AES_ECO55   (B7L7A1), 
AES_ECO57   (Q8XD38), AES_ECO5E   (B5Z3Y7), AES_ECO7I   (B7NIF4), 
AES_ECO81   (B7MQJ1), AES_ECO8A   (B7M3W8), AES_ECOBW   (C4ZUT0), 
AES_ECODH   (B1XFR3), AES_ECOHS   (A7ZXD4), AES_ECOK1   (A1A8E2), 
AES_ECOL5   (Q0TKG5), AES_ECOL6   (Q8FK82), AES_ECOLC   (B1IZB8), 
AES_ECOLI   (P23872), AES_ECOLU   (B7N929), AES_ECOSE   (B6I0B9), 
AES_ECOSM   (B1LJN4), AES_ECOUT   (Q1RF59), AES_SHIB3   (B2U4S9), 
AES_SHIBS   (Q325C0), AES_SHIF8   (Q0T7A9), AES_SHIFL   (Q83M39), 
AES_SHISS   (Q3Z4S3), BAH_STRHY   (Q01109), CXE16_ARATH (Q8LED9), 
CXE1_ACTER  (Q0ZPV7), CXE2_ARATH  (Q9SX78), CXE8_ARATH  (O64640), 
EST_ACILW   (P18773), GID1A_ARATH (Q9MAA7), GID1B_ARATH (Q9LYC1), 
GID1C_ARATH (Q940G6), GID1_ORYSJ  (Q6L545), LIP2_MORS1  (P24484), 
LIPS_BOVIN  (P16386), LIPS_HUMAN  (Q05469), LIPS_MOUSE  (P54310), 
LIPS_PIG    (Q68J42), LIPS_RAT    (P15304), LIPS_SPETR  (Q9R101)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
AAAD_HUMAN  (P22760), AAAD_RABIT  (Q7M370), ADCL2_HUMAN (Q6P093), 
ADCL3_HUMAN (Q5VUY0), ADCL3_MOUSE (A2A7Z8), ADCL4_HUMAN (Q5VUY2), 
ADCL4_MOUSE (Q8BM81), AES_SALA4   (B5EXN3), AES_SALCH   (Q57S73), 
AES_SALDC   (B5FLK0), AES_SALEP   (B5QU79), AES_SALNS   (B4SWY4), 
AES_SALPA   (Q5PFJ2), AES_SALPB   (A9MW81), AES_SALPK   (B5BD42), 
AES_SALSV   (B4TMG8), AES_SALTI   (Q8Z8T1), AES_SALTY   (Q8ZRA1), 
CXE11_ARATH (Q9LK21), CXE12_ARATH (Q9SMN0), CXE13_ARATH (Q9SMM9), 
CXE15_ARATH (Q9FG13), CXE17_ARATH (Q9LFR7), CXE18_ARATH (Q9LT10), 
CXE1_ARATH  (Q9LMA7), CXE20_ARATH (Q9LVB8), CXE3_ARATH  (Q9FX92), 
CXE4_ARATH  (Q9FX93), CXE5_ARATH  (Q9FX94), CXE6_ARATH  (Q9SX25), 
CXE7_ARATH  (Q9ZQ91), CXE9_ARATH  (O64641), LIPR_MYCTU  (O53301), 
MLHB_RHOER  (Q9EX73), NCEH1_HUMAN (Q6PIU2), NCEH1_MOUSE (Q8BLF1), 
NCEH1_PONAB (Q5R8Y5)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 2O7R; 2O7V; 2ZSH; 2ZSI; 3EBL; 3ED1;

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