PROSITE logo

PROSITE entry PS01180


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS01180
Entry name [info] CUB
Accession [info] PS01180
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00908
Associated ProRule [info] PRU00059

Name and characterization of the entry

Description [info] CUB domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=113;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=110;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.4270475; R2=0.0141260; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6357.4711914; R2=6.2621794; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=501; H_SCORE=9495; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=360; H_SCORE=8612; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-100; E1=-100; MI=-210; MD=-210; IM=0; DM=0;
...
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 608 in 206 different sequences
Number of true positive hits 608 in 206 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.75 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 27
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, P_Bucher
Feature key [info] DOMAIN
Feature description [info] CUB
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
206 sequences

AGRB3_HUMAN (O60242), AGRG6_DANRE (C6KFA3), AGRG6_HUMAN (Q86SQ4), 
» more

UniProtKB/Swiss-Prot
False negative sequences
14 sequences

AGRB3_MOUSE (Q80ZF8), ATS13_HUMAN (Q76LX8), ATS13_MOUSE (Q769J6), 
» more

PDB
[Detailed view]
55 PDB

1NT0; 1NZI; 1SFP; 1SPP; 1SZB; 2QQK; 2QQL; 2QQM; 2QQO; 2WNO; 3DEM; 3KQ4;
» more