Entry: PS01185

General information about the entry

Entry name [info] CTCK_1
Accession [info] PS01185
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); JUN-2015 (INFO UPDATE).
PROSITE Doc. [info] PDOC00912

Name and characterization of the entry

Description [info] C-terminal cystine knot signature.
Pattern [info]
C-C-x(13)-C-x(2)-[GN]-x(12)-C-x-C-x(2,4)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 48 in 48 different sequences
Number of true positive hits 48 in 48 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 33
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 59.26 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 4
Site [info] disulfide at position 8
Site [info] disulfide at position 10
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
48 sequences

CTGF_BOVIN  (O18739), CTGF_HUMAN  (P29279), CTGF_MOUSE  (P29268), 
CTGF_PIG    (O19113), CTGF_RAT    (Q9R1E9), CYR61_CHICK (P19336), 
CYR61_HUMAN (O00622), CYR61_MOUSE (P18406), CYR61_PANTR (A5A6L1), 
CYR61_RAT   (Q9ES72), GPHA2_MOUSE (Q925Q5), GPHA2_RAT   (Q925Q4), 
HMCT_BOMMO  (P98092), MUC19_HUMAN (Q7Z5P9), MUC19_MOUSE (Q6PZE0), 
MUC2L_RAT   (P98089), MUC2_HUMAN  (Q02817), MUC2_MOUSE  (Q80Z19), 
MUC5A_HUMAN (P98088), MUC5B_HUMAN (Q9HC84), MUCAP_PIG   (P12021), 
MUCB1_XENLA (P38565), MUCS_BOVIN  (P98091), NDP_BOVIN   (Q2KI78), 
NDP_HUMAN   (Q00604), NDP_MACFA   (Q60HE4), NDP_MOUSE   (P48744), 
NOV_CHICK   (P28686), NOV_COTJA   (P42642), NOV_HUMAN   (P48745), 
NOV_MOUSE   (Q64299), NOV_RAT     (Q9QZQ5), SLIT1_HUMAN (O75093), 
SLIT1_MOUSE (Q80TR4), SLIT1_RAT   (O88279), SLIT2_HUMAN (O94813), 
SLIT2_MOUSE (Q9R1B9), SLIT3_HUMAN (O75094), SLIT3_MOUSE (Q9WVB4), 
SLIT3_RAT   (O88280), SLIT_DROME  (P24014), VWF_CANFA   (Q28295), 
VWF_HUMAN   (P04275), VWF_MOUSE   (Q8CIZ8), VWF_PIG     (Q28833), 
WISP1_HUMAN (O95388), WISP1_MOUSE (O54775), WISP1_RAT   (Q99PP0)
» More

UniProtKB/Swiss-Prot
False negative sequences
33 sequences

BURS_AEDAE  (P85316), BURS_ANOGA  (Q66Q82), BURS_APIME  (A2VB89), 
BURS_BOMMO  (Q566B1), BURS_CULPP  (P85315), BURS_DROME  (Q9VD83), 
BURS_MANSE  (Q4FCM6), CER1_CHICK  (Q9PWB0), CER1_HUMAN  (O95813), 
CER1_MOUSE  (O55233), CER1_XENLA  (P70041), CER1_XENTR  (Q07G34), 
NOV_XENLA   (P51609), PBURS_ANOGA (Q566B3), PBURS_APIME (A2VB90), 
PBURS_BOMMO (Q566B2), PBURS_DROME (Q9VJS7), SOSD1_CHICK (Q6VYA3), 
SOSD1_HUMAN (Q6X4U4), SOSD1_MOUSE (Q9CQN4), SOSD1_PONAB (Q5R5D2), 
SOSD1_RAT   (Q642G2), SOST_BOVIN  (Q9BG79), SOST_CHLAE  (Q9BG78), 
SOST_HUMAN  (Q9BQB4), SOST_MOUSE  (Q99P68), SOST_RAT    (Q99P67), 
SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), SSPO_HUMAN  (A2VEC9), 
SSPO_MOUSE  (Q8CG65), SSPO_RAT    (Q700K0), WISP3_HUMAN (O95389)
» More

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

BURS_PERAM  (P84118), VWF_BOVIN   (P80012)

		
PDB
[Detailed view]
2 PDB

4MY2; 4NT5

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission