Entry: PS01206

General information about the entry
Entry name ASC
Accession number PS01206
Entry type PATTERN
Date NOV-1997 (CREATED); APR-2006 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00926
Name and characterization of the entry
DescriptionAmiloride-sensitive sodium channels signature.
Pattern Y-x(2)-[EQTFPMSI]-x-C-x(3)-C-x-[QTAVKS]-x(2)-[LIVMT]-[LIVMSAQ]-x(2)-C-x- C.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 58 hits in 58 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 58 hits in 58 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 6
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 2
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 90.62 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 2
Cross-references
UniProtKB/Swiss-Prot True positive hits:
ASI1A_DANRE (Q708S8), ASI1B_DANRE (Q708S7), ASI1C_DANRE (Q708S6), 
ASI4A_DANRE (Q708S4), ASI4B_DANRE (Q708S3), ASIC1_CAEEL (O01635), 
ASIC1_CHICK (Q1XA76), ASIC1_HUMAN (P78348), ASIC1_MOUSE (Q6NXK8), 
ASIC1_OPSTA (Q7T1N4), ASIC1_RAT   (P55926), ASIC2_CAEEL (Q22851), 
ASIC2_DANRE (Q708S5), ASIC2_HUMAN (Q16515), ASIC2_MOUSE (Q925H0), 
ASIC2_RAT   (Q62962), ASIC3_HUMAN (Q9UHC3), ASIC3_MOUSE (Q6X1Y6), 
ASIC3_RAT   (O35240), ASIC4_HUMAN (Q96FT7), ASIC4_MOUSE (Q7TNS7), 
ASIC4_RAT   (Q9JHS6), DEG1_CAEEL  (P24585), DEL1_CAEEL  (Q19038), 
FANA_HELAS  (Q25011), MEC10_CAEBR (Q60NC0), MEC10_CAEEL (P34886), 
MEC4_CAEBR  (Q17298), MEC4_CAEEL  (P24612), NACH_DROAN  (O61370), 
NACH_DROME  (O61365), NACH_DROVI  (Q9NJP2), PPK11_DROME (Q9VL84), 
SCNNA_BOVIN (P55270), SCNNA_CAVPO (Q9R1N2), SCNNA_CHICK (Q92075), 
SCNNA_HUMAN (P37088), SCNNA_MOUSE (Q61180), SCNNA_RABIT (O97741), 
SCNNA_RAT   (P37089), SCNNA_XENLA (P51167), SCNNB_HUMAN (P51168), 
SCNNB_LITCT (Q9W754), SCNNB_MOUSE (Q9WU38), SCNNB_RABIT (O97742), 
SCNNB_RAT   (P37090), SCNNB_XENLA (P51169), SCNNC_XENLA (O13262), 
SCNND_HUMAN (P51172), SCNND_PANTR (O46547), SCNNG_HUMAN (P51170), 
SCNNG_MOUSE (Q9WU39), SCNNG_RABIT (Q28738), SCNNG_RAT   (P37091), 
SCNNG_XENLA (P51171), SCNNH_XENLA (O13263), UN105_CAEEL (Q09274), 
UNC8_CAEEL  (Q21974)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
ASIC5_HUMAN (Q9NY37), ASIC5_MOUSE (Q9R0Y1), ASIC5_RAT   (Q9R0W5), 
DEGZ_CAEEL  (Q10025), PPK19_DROME (Q9VAJ3), PPK28_DROME (Q86LG1)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
SCNNB_CANFA (Q95165), SCNNB_SHEEP (O62816)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 2QTS; 3HGC; 3IJ4; 3S3W; 3S3X; 4FZ0; 4FZ1;

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