Entry: PS01208

General information about the entry
Entry name VWFC_1
Accession number PS01208
Entry type PATTERN
Date NOV-1997 (CREATED); DEC-2004 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00928
Name and characterization of the entry
DescriptionVWFC domain signature.
Pattern C-x(2,3)-C-{CG}-C-x(6,14)-C-x(3,4)-C-x(2,10)-C-x(9,16)-C-C-x(2,4)-C.
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 265 hits in 134 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 248 hits in 120 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 17 hits in 14 different sequences
  • Number of known missed hits: 19
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 4
  • Precision (true hits / (true hits + false positives)): 93.58 %
  • Recall (true hits / (true hits + false negatives)): 92.88 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 20
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
BMPER_HUMAN (Q8N8U9), BMPER_MOUSE (Q8CJ69), CHRD_DANRE  (O57472), 
CHRD_HUMAN  (Q9H2X0), CHRD_MOUSE  (Q9Z0E2), CHRD_RAT    (Q63148), 
CHRD_XENLA  (Q91713), CO1A1_BOVIN (P02453), CO1A1_CANFA (Q9XSJ7), 
CO1A1_CHICK (P02457), CO1A1_CYNPY (Q9YIB4), CO1A1_HUMAN (P02452), 
CO1A1_MOUSE (P11087), CO1A1_RAT   (P02454), CO2A1_BOVIN (P02459), 
CO2A1_HUMAN (P02458), CO2A1_MOUSE (P28481), CO2A1_XENLA (Q91717), 
CO2A1_XENTR (Q6P4Z2), CO3A1_CHICK (P12105), CO3A1_HUMAN (P02461), 
CO3A1_MOUSE (P08121), CO3A1_RAT   (P13941), CO5A2_HUMAN (P05997), 
CO5A2_MOUSE (Q3U962), CRDL1_CHICK (Q90ZD5), CRDL1_HUMAN (Q9BU40), 
CRDL1_MOUSE (Q920C1), CRDL1_RAT   (Q76LD0), CRDL2_HUMAN (Q6WN34), 
CRDL2_MOUSE (Q8VEA6), CRIM1_CHICK (Q8AWW5), CRIM1_DANRE (Q7T3Q2), 
CRIM1_HUMAN (Q9NZV1), CRIM1_MOUSE (Q9JLL0), CTGF_BOVIN  (O18739), 
CTGF_HUMAN  (P29279), CTGF_MOUSE  (P29268), CTGF_PIG    (O19113), 
CTGF_RAT    (Q9R1E9), CYR61_CHICK (P19336), CYR61_HUMAN (O00622), 
CYR61_MOUSE (P18406), CYR61_PANTR (A5A6L1), CYR61_RAT   (Q9ES72), 
ECM2_BOVIN  (Q3MHH9), ECM2_HUMAN  (O94769), ECM2_MOUSE  (Q5FW85), 
FRAS1_HUMAN (Q86XX4), FRAS1_MOUSE (Q80T14), IDD_HUMAN   (P98153), 
IDD_MOUSE   (P98154), KCP_HUMAN   (Q6ZWJ8), KCP_MOUSE   (Q3U492), 
KCP_XENLA   (Q9IBG7), MUC19_MOUSE (Q6PZE0), MUC2L_RAT   (P98089), 
MUC2_HUMAN  (Q02817), MUC2_MOUSE  (Q80Z19), MUC5A_HUMAN (P98088), 
MUC5B_CHICK (Q98UI9), MUC5B_HUMAN (Q9HC84), MUCAP_PIG   (P12021), 
MUCB1_XENLA (P38565), MUCS_BOVIN  (P98091), NELL1_HUMAN (Q92832), 
NELL1_MOUSE (Q2VWQ2), NELL1_RAT   (Q62919), NELL2_BOVIN (A6QR11), 
NELL2_DANRE (A1A5Y0), NELL2_HUMAN (Q99435), NELL2_MOUSE (Q61220), 
NELL2_PONAB (Q5R3Z7), NELL2_RAT   (Q62918), NELL2_XENLA (Q7ZXL5), 
NELL2_XENTR (A2VCU8), NEL_CHICK   (Q90827), NOV_CHICK   (P28686), 
NOV_COTJA   (P42642), NOV_HUMAN   (P48745), NOV_MOUSE   (Q64299), 
NOV_RAT     (Q9QZQ5), NOV_XENLA   (P51609), PXDNL_HUMAN (A1KZ92), 
PXDN_DROME  (Q9VZZ4), PXDN_HUMAN  (Q92626), PXDN_MOUSE  (Q3UQ28), 
PXDN_XENTR  (A4IGL7), SAS_DROME   (Q04164), SOG_DROME   (Q24025), 
SSPO_BOVIN  (P98167), SSPO_CHICK  (Q2PC93), SSPO_HUMAN  (A2VEC9), 
SSPO_MOUSE  (Q8CG65), SSPO_RAT    (Q700K0), TSP1_BOVIN  (Q28178), 
TSP1_HUMAN  (P07996), TSP1_MOUSE  (P35441), TSP1_XENLA  (P35448), 
TSP2_BOVIN  (Q95116), TSP2_CHICK  (P35440), TSP2_HUMAN  (P35442), 
TSP2_MOUSE  (Q03350), VWC2L_DANRE (B0UZC8), VWC2L_HUMAN (B2RUY7), 
VWC2L_MOUSE (Q505H4), VWC2_HUMAN  (Q2TAL6), VWC2_MOUSE  (Q8C8N3), 
VWCE_HUMAN  (Q96DN2), VWCE_MOUSE  (Q3U515), VWF_CANFA   (Q28295), 
VWF_HUMAN   (P04275), VWF_MOUSE   (Q8CIZ8), VWF_PIG     (Q28833), 
WISP1_HUMAN (O95388), WISP1_MOUSE (O54775), WISP1_RAT   (Q99PP0), 
WISP2_HUMAN (O76076), WISP2_MOUSE (Q9Z0G4), WISP2_RAT   (Q9JHC6)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
AMNLS_CANFA (Q6UKI2), AMNLS_HUMAN (Q9BXJ7), AMNLS_MOUSE (Q99JB7), 
FSTL1_BOVIN (Q58D84), FSTL1_HUMAN (Q12841), FSTL1_MACFA (Q9GKY0), 
FSTL1_MOUSE (Q62356), FSTL1_PONAB (Q5R9Y1), FSTL1_RAT   (Q62632), 
HMCT_BOMMO  (P98092), JAG1B_DANRE (Q90Y54), JAG2_HUMAN  (Q9Y219), 
MUC19_HUMAN (Q7Z5P9), MUC2_RAT    (Q62635), VWC2L_MACFA (Q95K75), 
ZAN_HUMAN   (Q9Y493), ZAN_MOUSE   (O88799), ZAN_PIG     (Q28983), 
ZAN_RABIT   (P57999)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
CO1A1_RABIT (P02456), CO2A1_CHICK (P02460), CO3A1_BOVIN (P04258), 
VWF_BOVIN   (P80012)
False positive hits (sequences which do not belong to the set under consideration):
KR510_HUMAN (Q6L8G5), KRA51_HUMAN (Q6L8H4), KRA51_MOUSE (Q64507), 
KRA53_HUMAN (Q6L8H2), KRA54_HUMAN (Q6L8H1), KRA56_HUMAN (Q6L8G9), 
KRA57_HUMAN (Q6L8G8), KRA58_HUMAN (O75690), KRA59_HUMAN (P26371), 
KRUC_SHEEP  (P26372), MCSP_MOUSE  (P15265), MCSP_RAT    (Q64298), 
MTCU_CALSI  (Q9U620), MT_CARMA    (P55948)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		 1U5M;

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