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Entry: PS01226
General information about the entry
Entry nameHMG_COA_SYNTHASE
Accession numberPS01226
Entry typePATTERN
DateNOV-1997 (CREATED); NOV-1997 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00942
Associated ProRulePRU10116
Name and characterization of the entry
DescriptionHydroxymethylglutaryl-coenzyme A synthase active site.
PatternN-x-[DN]-[IV]-E-G-[IV]-D-x(2)-N-A-C-[FY]-x-G.
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 17 hits in 17 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 17 hits in 17 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 1
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 94.44 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 12,active_site
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
HMCS1_BLAGE (P54961), HMCS1_CHICK (P23228), HMCS1_CRIGR (P13704), 
HMCS1_HUMAN (Q01581), HMCS1_MOUSE (Q8JZK9), HMCS1_PONAB (Q5R7Z9), 
HMCS1_RAT   (P17425), HMCS2_BLAGE (P54870), HMCS2_BOVIN (Q2KIE6), 
HMCS2_HUMAN (P54868), HMCS2_MOUSE (P54869), HMCS2_PIG   (O02734), 
HMCS2_RAT   (P22791), HMCS_ARATH  (P54873), HMCS_CAEEL  (P54871), 
HMCS_SCHPO  (P54874), HMCS_YEAST  (P54839)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
HMCSA_DICDI (P54872)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

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PDB
[Detailed view]		2WYA;

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