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Entry: PS01258
General information about the entry
Entry nameBH2
Accession numberPS01258
Entry typePATTERN
DateNOV-1997 (CREATED); NOV-1997 (DATA UPDATE); DEC-2011 (INFO UPDATE).
PROSITE DocumentationPDOC00829
Name and characterization of the entry
DescriptionApoptosis regulator, Bcl-2 family BH2 motif signature.
PatternW-[LIM]-x(3)-[GR]-G-[WQ]-[DENSAV]-x-[FLGA]-[LIVFTC].
Numerical results
  • UniProtKB/Swiss-Prot release number: 01, total number of sequence entries in that release: 534242.
  • Total number of hits in UniProtKB/Swiss-Prot: 47 hits in 47 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 45 hits in 45 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 2 hits in 2 different sequences
  • Number of known missed hits: 17
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 95.74 %
  • Recall (true hits / (true hits + false negatives)): 72.58 %
Comments
  • Taxonomic range: Eukaryotes, Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
AR11_XENLA  (Q91828), AR1_XENLA   (Q91827), ARBH_ASFB7  (P42485), 
ARBH_ASFE4  (Q07818), ARBH_ASFK5  (P0C8H4), ARBH_ASFM2  (Q07819), 
ARBH_ASFP4  (P0C8H5), ARBH_ASFWA  (P0C8H6), B2CL1_CHICK (Q07816), 
B2CL1_HUMAN (Q07817), B2CL1_MOUSE (Q64373), B2CL1_PIG   (O77737), 
B2CL1_RAT   (P53563), B2CL2_BOVIN (Q1RMX3), B2CL2_CANFA (Q45T69), 
B2CL2_HUMAN (Q92843), B2CL2_MOUSE (P70345), B2L10_HUMAN (Q9HD36), 
B2L10_RAT   (Q99M66), B2LA1_BOVIN (Q3C2I0), B2LA1_HUMAN (Q16548), 
B2LA1_MOUSE (Q07440), BAK_HUMAN   (Q16611), BAK_MOUSE   (O08734), 
BAX_BOVIN   (O02703), BAX_HUMAN   (Q07812), BAX_MOUSE   (Q07813), 
BAX_RAT     (Q63690), BCL2_BOVIN  (O02718), BCL2_CANFA  (Q6R755), 
BCL2_CHICK  (Q00709), BCL2_CRIGR  (Q9JJV8), BCL2_HUMAN  (P10415), 
BCL2_MOUSE  (P10417), BCL2_RAT    (P49950), EAR_EBVA8   (P0C6Z1), 
EAR_EBVB9   (P03182), EAR_EBVG    (P0C736), MCL1_CANFA  (Q8HYS5), 
MCL1_FELCA  (Q7YRZ9), MCL1_HUMAN  (Q07820), MCL1_MOUSE  (P97287), 
MCL1_RAT    (Q9Z1P3), NR13_CHICK  (Q90ZN1), NR13_COTJA  (Q90343)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
B2L10_MOUSE (Q9Z0F3), B2L12_HUMAN (Q9HB09), B2L13_HUMAN (Q9BXK5), 
B2L13_MOUSE (P59017), B2L14_BOVIN (Q5E9L4), B2L14_HUMAN (Q9BZR8), 
B2L14_MOUSE (Q9CPT0), B2L14_RAT   (Q6AYK4), BOKA_DANRE  (Q6DC66), 
BOKB_DANRE  (Q7T381), BOK_CHICK   (Q9I8I2), BOK_HUMAN   (Q9UMX3), 
BOK_MOUSE   (O35425), BOK_RAT     (Q792S6), CED9_CAEBR  (P41957), 
CED9_CAEEL  (P41958), V039_FOWPN  (Q9J5G4)
False positive hits (sequences which do not belong to the set under consideration):
DLD3_YEAST  (P39976), FRS2_ARATH  (Q3EBQ3)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		1AF3; 1BXL; 1F16; 1G5J; 1G5M; 1GJH; 1LXL; 1MAZ; 1MK3; 1O0L; 1PQ0; 1PQ1; 1Q59; 1R2D; 1R2E; 1R2G; 1R2H; 1R2I; 1WSX; 1YSG; 1YSI; 1YSN; 1YSW; 1ZY3; 2B48; 2BZW; 2IMS; 2IMT; 2JCN; 2JM6; 2K7W; 2KBW; 2NL9; 2NLA; 2O1Y; 2O21; 2O22; 2O2F; 2O2M; 2O2N; 2P1L; 2PON; 2PQK; 2ROC; 2ROD; 2V6Q; 2VM6; 2VOF; 2VOG; 2VOH; 2VOI; 2W3L; 2WH6; 2XA0; 2XPX; 2Y6W; 2YJ1; 2YV6; 2YXJ; 3CVA; 3D7V; 3FDL; 3FDM; 3I1H; 3IHC; 3IHD; 3IHE; 3IHF; 3IIG; 3IIH; 3ILB; 3ILC; 3INQ; 3IO8; 3IO9; 3KJ0; 3KJ1; 3KJ2; 3KZ0; 3MK8; 3MQP; 3PK1; 3PL7; 3QKD; 3R85;

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