Entry: PS01258

General information about the entry

Entry name [info] BH2
Accession [info] PS01258
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00829

Name and characterization of the entry

Description [info] Apoptosis regulator, Bcl-2 family BH2 motif signature.
Pattern [info]
W-[LIM]-x(3)-[GR]-G-[WQ]-[DENSAV]-x-[FLGA]-[LIVFTC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_07 which contains 551'705 sequence entries.


Total number of hits 47 in 47 different sequences
Number of true positive hits 45 in 45 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 17
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.74 %
Recall (true positives / (true positives + false negatives)) 72.58 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
45 sequences

AR11_XENLA  (Q91828    ), AR1_XENLA   (Q91827    ), ARBH_ASFB7  (P42485    ), 
ARBH_ASFE4  (Q07818    ), ARBH_ASFK5  (P0C8H4    ), ARBH_ASFM2  (Q07819    ), 
ARBH_ASFP4  (P0C8H5    ), ARBH_ASFWA  (P0C8H6    ), B2CL1_CHICK (Q07816    ), 
B2CL1_HUMAN (Q07817    ), B2CL1_MOUSE (Q64373    ), B2CL1_PIG   (O77737    ), 
B2CL1_RAT   (P53563    ), B2CL2_BOVIN (Q1RMX3    ), B2CL2_CANLF (Q45T69    ), 
B2CL2_HUMAN (Q92843    ), B2CL2_MOUSE (P70345    ), B2L10_HUMAN (Q9HD36    ), 
B2L10_RAT   (Q99M66    ), B2LA1_BOVIN (Q3C2I0    ), B2LA1_HUMAN (Q16548    ), 
B2LA1_MOUSE (Q07440    ), BAK_HUMAN   (Q16611    ), BAK_MOUSE   (O08734    ), 
BAX_BOVIN   (O02703    ), BAX_HUMAN   (Q07812    ), BAX_MOUSE   (Q07813    ), 
BAX_RAT     (Q63690    ), BCL2_BOVIN  (O02718    ), BCL2_CANLF  (Q6R755    ), 
BCL2_CHICK  (Q00709    ), BCL2_CRIGR  (Q9JJV8    ), BCL2_HUMAN  (P10415    ), 
BCL2_MOUSE  (P10417    ), BCL2_RAT    (P49950    ), EAR_EBVA8   (P0C6Z1    ), 
EAR_EBVB9   (P03182    ), EAR_EBVG    (P0C736    ), MCL1_CANLF  (Q8HYS5    ), 
MCL1_FELCA  (Q7YRZ9    ), MCL1_HUMAN  (Q07820    ), MCL1_MOUSE  (P97287    ), 
MCL1_RAT    (Q9Z1P3    ), NR13_CHICK  (Q90ZN1    ), NR13_COTJA  (Q90343    )
» more

UniProtKB/Swiss-Prot
False negative sequences
17 sequences

B2L10_MOUSE (Q9Z0F3    ), B2L12_HUMAN (Q9HB09    ), B2L13_HUMAN (Q9BXK5    ), 
B2L13_MOUSE (P59017    ), B2L14_BOVIN (Q5E9L4    ), B2L14_HUMAN (Q9BZR8    ), 
B2L14_MOUSE (Q9CPT0    ), B2L14_RAT   (Q6AYK4    ), BOKA_DANRE  (Q6DC66    ), 
BOKB_DANRE  (Q7T381    ), BOK_CHICK   (Q9I8I2    ), BOK_HUMAN   (Q9UMX3    ), 
BOK_MOUSE   (O35425    ), BOK_RAT     (Q792S6    ), CED9_CAEBR  (P41957    ), 
CED9_CAEEL  (P41958    ), V039_FOWPN  (Q9J5G4    )
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

DLD3_YEAST  (P39976    ), FRS2_ARATH  (Q3EBQ3    )

		
PDB
[Detailed view]
169 PDB

1AF3; 1BXL; 1F16; 1G5J; 1G5M; 1GJH; 1LXL; 1MAZ; 1MK3; 1O0L; 1PQ0; 1PQ1; 1Q59; 1R2D; 1R2E; 1R2G; 1R2H; 1R2I; 1WSX; 1YSG; 1YSI; 1YSN; 1YSW; 1ZY3; 2B48; 2BZW; 2IMS; 2IMT; 2JCN; 2JM6; 2K7W; 2KBW; 2LP8; 2LPC; 2LR1; 2M03; 2M04; 2M5B; 2ME8; 2ME9; 2MEJ; 2MHS; 2NL9; 2NLA; 2O1Y; 2O21; 2O22; 2O2F; 2O2M; 2O2N; 2P1L; 2PON; 2PQK; 2ROC; 2ROD; 2V6Q; 2VM6; 2VOF; 2VOG; 2VOH; 2VOI; 2W3L; 2WH6; 2XA0; 2XPX; 2Y6W; 2YJ1; 2YQ6; 2YQ7; 2YV6; 2YXJ; 3CVA; 3D7V; 3FDL; 3FDM; 3I1H; 3IHC; 3IHD; 3IHE; 3IHF; 3IIG; 3IIH; 3ILB; 3ILC; 3INQ; 3IO8; 3IO9; 3KJ0; 3KJ1; 3KJ2; 3KZ0; 3MK8; 3MQP; 3PK1; 3PL7; 3QKD; 3R85; 3SP7; 3SPF; 3WIX; 3WIY; 3WIZ; 3ZK6; 3ZLN; 3ZLO; 3ZLR; 4A1U; 4A1W; 4AQ3; 4BD2; 4BD6; 4BD7; 4BD8; 4BPI; 4BPJ; 4BPK; 4C52; 4C5D; 4CIM; 4CIN; 4EHR; 4G35; 4HNJ; 4HW2; 4HW3; 4HW4; 4IEH; 4K5A; 4K5B; 4LVT; 4LXD; 4MAN; 4OQ5; 4OQ6; 4OYD; 4PPI; 4QNQ; 4QVE; 4QVF; 4QVX; 4TUH; 4U2U; 4WGI; 4WMR; 4WMS; 4WMT; 4WMU; 4WMV; 4WMW; 4WMX; 4YJ4; 4YK9; 4Z9V; 4ZBF; 4ZBI; 4ZEQ; 4ZIE; 4ZIF; 4ZIG; 4ZIH; 4ZII; 5AGW; 5AGX; 5C3F; 5C3G; 5FC4; 5FCG; 5FDO; 5FDR
» more

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