Entry: PS01259

General information about the entry

Entry name [info] BH3
Accession [info] PS01259
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); JUL-1998 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00829

Name and characterization of the entry

Description [info] Apoptosis regulator, Bcl-2 family BH3 motif signature.
Pattern [info]
[LIVAT]-x(3)-L-[KARQ]-x-[IVAL]-G-D-[DESG]-[LIMFV]-[DENSHQ]-[LVSHRQ]-
[NSR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 30 in 30 different sequences
Number of true positive hits 30 in 30 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 38
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 44.12 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
30 sequences

B2CL1_CHICK (Q07816    ), B2CL1_HUMAN (Q07817    ), B2CL1_MOUSE (Q64373    ), 
B2CL1_PIG   (O77737    ), B2CL1_RAT   (P53563    ), BAK_HUMAN   (Q16611    ), 
BAK_MOUSE   (O08734    ), BAX_BOVIN   (O02703    ), BAX_HUMAN   (Q07812    ), 
BAX_MOUSE   (Q07813    ), BAX_RAT     (Q63690    ), BCL2_BOVIN  (O02718    ), 
BCL2_CANLF  (Q6R755    ), BCL2_CHICK  (Q00709    ), BCL2_CRIGR  (Q9JJV8    ), 
BCL2_HUMAN  (P10415    ), BCL2_MOUSE  (P10417    ), BCL2_RAT    (P49950    ), 
BID_HUMAN   (P55957    ), BID_MOUSE   (P70444    ), BID_RAT     (Q9JLT6    ), 
BIK_HUMAN   (Q13323    ), HRK_HUMAN   (O00198    ), HRK_MOUSE   (P62816    ), 
HRK_RAT     (P62817    ), MCL1_CANLF  (Q8HYS5    ), MCL1_FELCA  (Q7YRZ9    ), 
MCL1_HUMAN  (Q07820    ), MCL1_MOUSE  (P97287    ), MCL1_RAT    (Q9Z1P3    )
» more

UniProtKB/Swiss-Prot
False negative sequences
38 sequences

APR_CANLF   (Q1PCT2    ), APR_HUMAN   (Q13794    ), APR_MOUSE   (Q9JM54    ), 
APR_RAT     (Q5U777    ), B2L11_HUMAN (O43521    ), B2L11_MOUSE (O54918    ), 
B2L11_RAT   (O88498    ), B2L13_HUMAN (Q9BXK5    ), B2L13_MOUSE (P59017    ), 
B2L14_BOVIN (Q5E9L4    ), B2L14_HUMAN (Q9BZR8    ), B2L14_MOUSE (Q9CPT0    ), 
B2L14_RAT   (Q6AYK4    ), BAD_HUMAN   (Q92934    ), BAD_MOUSE   (Q61337    ), 
BAD_RAT     (O35147    ), BBC3_HUMAN  (Q9BXH1    ), BBC3_MOUSE  (Q99ML1    ), 
BBC3_RAT    (Q80ZG6    ), BID_CHICK   (Q8JGM8    ), BID_PIG     (Q4JHS0    ), 
BMF_HUMAN   (Q96LC9    ), BMF_MOUSE   (Q91ZE9    ), BMF_RAT     (Q8K589    ), 
BNI3L_BOVIN (Q3T013    ), BNI3L_HUMAN (O60238    ), BNI3L_MOUSE (Q9Z2F7    ), 
BNIP3_BOVIN (Q32KN2    ), BNIP3_HUMAN (Q12983    ), BNIP3_MOUSE (O55003    ), 
BOKA_DANRE  (Q6DC66    ), BOKB_DANRE  (Q7T381    ), BOK_CHICK   (Q9I8I2    ), 
BOK_HUMAN   (Q9UMX3    ), BOK_MOUSE   (O35425    ), BOK_RAT     (Q792S6    ), 
BOP_HUMAN   (Q7L3V2    ), BOP_PONAB   (Q5R6M8    )
» more

PDB
[Detailed view]
163 PDB

1AF3; 1BXL; 1DDB; 1F16; 1G5J; 1G5M; 1GJH; 1LXL; 1MAZ; 1PQ0; 1PQ1; 1R2D; 1R2E; 1R2H; 1R2I; 1WSX; 1YSG; 1YSI; 1YSN; 1YSW; 1ZY3; 2B48; 2BID; 2BZW; 2IMS; 2IMT; 2JBY; 2JCN; 2JM6; 2K7W; 2KBW; 2L58; 2LP8; 2LPC; 2LR1; 2M03; 2M04; 2M5B; 2M5I; 2ME8; 2ME9; 2MEJ; 2MHS; 2NL9; 2NLA; 2O1Y; 2O21; 2O22; 2O2F; 2O2M; 2O2N; 2P1L; 2PON; 2PQK; 2ROC; 2ROD; 2VOH; 2VOI; 2W3L; 2XA0; 2XPX; 2YJ1; 2YQ6; 2YQ7; 2YV6; 2YXJ; 3CVA; 3D7V; 3FDL; 3FDM; 3IHC; 3IHD; 3IHE; 3IHF; 3IIG; 3IIH; 3ILB; 3ILC; 3INQ; 3IO8; 3IO9; 3KJ0; 3KJ1; 3KJ2; 3KZ0; 3MK8; 3PK1; 3PL7; 3QBR; 3QKD; 3R85; 3SP7; 3SPF; 3WIX; 3WIY; 3WIZ; 3ZK6; 3ZLN; 3ZLO; 3ZLR; 4A1U; 4A1W; 4AQ3; 4BD2; 4BD6; 4BD7; 4BD8; 4BDU; 4BPI; 4BPJ; 4BPK; 4C52; 4C5D; 4CIN; 4D2L; 4EHR; 4G35; 4HNJ; 4HW2; 4HW3; 4HW4; 4IEH; 4LVT; 4LXD; 4MAN; 4OQ5; 4OQ6; 4PPI; 4QNQ; 4QVE; 4QVF; 4QVX; 4TUH; 4U2U; 4U2V; 4UF1; 4UF2; 4WGI; 4WMR; 4WMS; 4WMT; 4WMU; 4WMV; 4WMW; 4WMX; 4YJ4; 4Z9V; 4ZBF; 4ZBI; 4ZEQ; 4ZIE; 4ZIF; 4ZIG; 4ZIH; 4ZII; 5AGW; 5AGX; 5AJJ; 5AJK; 5FC4; 5FCG; 5FDO; 5FDR
» more

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