Entry: PS01259

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General information about the entry

Entry name [info] BH3
Accession [info] PS01259
Entry type [info] PATTERN
Date [info] NOV-1997 (CREATED); JUL-1998 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00829

Name and characterization of the entry

Description [info] Apoptosis regulator, Bcl-2 family BH3 motif signature.
Pattern [info]
[LIVAT]-x(3)-L-[KARQ]-x-[IVAL]-G-D-[DESG]-[LIMFV]-[DENSHQ]-[LVSHRQ]-
[NSR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 30 in 30 different sequences
Number of true positive hits 30 in 30 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 38
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 44.12 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
30 sequences

B2CL1_CHICK (Q07816), B2CL1_HUMAN (Q07817), B2CL1_MOUSE (Q64373), 
B2CL1_PIG   (O77737), B2CL1_RAT   (P53563), BAK_HUMAN   (Q16611), 
BAK_MOUSE   (O08734), BAX_BOVIN   (O02703), BAX_HUMAN   (Q07812), 
BAX_MOUSE   (Q07813), BAX_RAT     (Q63690), BCL2_BOVIN  (O02718), 
BCL2_CANFA  (Q6R755), BCL2_CHICK  (Q00709), BCL2_CRIGR  (Q9JJV8), 
BCL2_HUMAN  (P10415), BCL2_MOUSE  (P10417), BCL2_RAT    (P49950), 
BID_HUMAN   (P55957), BID_MOUSE   (P70444), BID_RAT     (Q9JLT6), 
BIK_HUMAN   (Q13323), HRK_HUMAN   (O00198), HRK_MOUSE   (P62816), 
HRK_RAT     (P62817), MCL1_CANFA  (Q8HYS5), MCL1_FELCA  (Q7YRZ9), 
MCL1_HUMAN  (Q07820), MCL1_MOUSE  (P97287), MCL1_RAT    (Q9Z1P3)
» More

UniProtKB/Swiss-Prot
False negative sequences
38 sequences

APR_CANFA   (Q1PCT2), APR_HUMAN   (Q13794), APR_MOUSE   (Q9JM54), 
APR_RAT     (Q5U777), B2L11_HUMAN (O43521), B2L11_MOUSE (O54918), 
B2L11_RAT   (O88498), B2L13_HUMAN (Q9BXK5), B2L13_MOUSE (P59017), 
B2L14_BOVIN (Q5E9L4), B2L14_HUMAN (Q9BZR8), B2L14_MOUSE (Q9CPT0), 
B2L14_RAT   (Q6AYK4), BAD_HUMAN   (Q92934), BAD_MOUSE   (Q61337), 
BAD_RAT     (O35147), BBC3_HUMAN  (Q9BXH1), BBC3_MOUSE  (Q99ML1), 
BBC3_RAT    (Q80ZG6), BID_CHICK   (Q8JGM8), BID_PIG     (Q4JHS0), 
BMF_HUMAN   (Q96LC9), BMF_MOUSE   (Q91ZE9), BMF_RAT     (Q8K589), 
BNI3L_BOVIN (Q3T013), BNI3L_HUMAN (O60238), BNI3L_MOUSE (Q9Z2F7), 
BNIP3_BOVIN (Q32KN2), BNIP3_HUMAN (Q12983), BNIP3_MOUSE (O55003), 
BOKA_DANRE  (Q6DC66), BOKB_DANRE  (Q7T381), BOK_CHICK   (Q9I8I2), 
BOK_HUMAN   (Q9UMX3), BOK_MOUSE   (O35425), BOK_RAT     (Q792S6), 
BOP_HUMAN   (Q7L3V2), BOP_PONAB   (Q5R6M8)
» More

PDB
[Detailed view]
124 PDB

1AF3; 1BXL; 1DDB; 1F16; 1G5J; 1G5M; 1GJH; 1LXL; 1MAZ; 1PQ0; 1PQ1; 1R2D; 1R2E; 1R2H; 1R2I; 1WSX; 1YSG; 1YSI; 1YSN; 1YSW; 1ZY3; 2B48; 2BID; 2BZW; 2IMS; 2IMT; 2JBY; 2JCN; 2JM6; 2K7W; 2KBW; 2L58; 2LP8; 2LPC; 2LR1; 2M03; 2M04; 2M5B; 2M5I; 2ME8; 2ME9; 2MEJ; 2NL9; 2NLA; 2O1Y; 2O21; 2O22; 2O2F; 2O2M; 2O2N; 2P1L; 2PON; 2PQK; 2ROC; 2ROD; 2VOH; 2VOI; 2W3L; 2XA0; 2XPX; 2YJ1; 2YQ6; 2YQ7; 2YV6; 2YXJ; 3CVA; 3D7V; 3FDL; 3FDM; 3IHC; 3IHD; 3IHE; 3IHF; 3IIG; 3IIH; 3ILB; 3ILC; 3INQ; 3IO8; 3IO9; 3KJ0; 3KJ1; 3KJ2; 3KZ0; 3MK8; 3PK1; 3PL7; 3QBR; 3QKD; 3R85; 3SP7; 3SPF; 3WIX; 3WIY; 3WIZ; 3ZK6; 3ZLN; 3ZLO; 3ZLR; 4A1U; 4A1W; 4AQ3; 4BD2; 4BD6; 4BD7; 4BD8; 4BDU; 4BPI; 4BPJ; 4BPK; 4C52; 4C5D; 4EHR; 4G35; 4HNJ; 4HW2; 4HW3; 4HW4; 4IEH; 4LVT; 4LXD; 4MAN; 4OQ5; 4OQ6
» More

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