Entry: PS01260

General information about the entry
Entry name BH4_1
Accession number PS01260
Entry type PATTERN
Date NOV-1997 (CREATED); NOV-1997 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation PDOC00829
Name and characterization of the entry
DescriptionApoptosis regulator, Bcl-2 family BH4 motif signature.
Pattern [DS]-[NT]-R-[AE]-[LI]-V-x-[KD]-[FY]-[LIV]-[GHS]-Y-K-L-[SR]-Q-[RK]-G- [HY]-x-[CW].
Numerical results
  • UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052.
  • Total number of hits in UniProtKB/Swiss-Prot: 16 hits in 16 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 16 hits in 16 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 10
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 61.54 %
Comments
  • Taxonomic range: Eukaryotes
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-Prot True positive hits:
B2CL1_CHICK (Q07816), B2CL1_HUMAN (Q07817), B2CL1_MOUSE (Q64373), 
B2CL1_PIG   (O77737), B2CL1_RAT   (P53563), B2CL2_BOVIN (Q1RMX3), 
B2CL2_CANFA (Q45T69), B2CL2_HUMAN (Q92843), B2CL2_MOUSE (P70345), 
BCL2_BOVIN  (O02718), BCL2_CANFA  (Q6R755), BCL2_CHICK  (Q00709), 
BCL2_CRIGR  (Q9JJV8), BCL2_HUMAN  (P10415), BCL2_MOUSE  (P10417), 
BCL2_RAT    (P49950)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
B2L13_HUMAN (Q9BXK5), B2L13_MOUSE (P59017), BOKA_DANRE  (Q6DC66), 
BOKB_DANRE  (Q7T381), BOK_CHICK   (Q9I8I2), BOK_HUMAN   (Q9UMX3), 
BOK_MOUSE   (O35425), BOK_RAT     (Q792S6), CED9_CAEBR  (P41957), 
CED9_CAEEL  (P41958)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

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PDB
[Detailed view]		 1AF3; 1BXL; 1G5J; 1G5M; 1GJH; 1LXL; 1MAZ; 1MK3; 1O0L; 1PQ0; 1PQ1; 1R2D; 1R2E; 1R2G; 1R2H; 1R2I; 1YSG; 1YSI; 1YSN; 1YSW; 1ZY3; 2B48; 2BZW; 2LP8; 2LPC; 2M03; 2M04; 2O1Y; 2O21; 2O22; 2O2F; 2P1L; 2PON; 2W3L; 2XA0; 2YJ1; 2YQ6; 2YQ7; 2YXJ; 3CVA; 3FDL; 3FDM; 3IHC; 3IHD; 3IHE; 3IHF; 3IIG; 3IIH; 3ILB; 3ILC; 3INQ; 3IO8; 3PL7; 3QKD; 3R85; 3SP7; 3SPF; 4A1U; 4A1W; 4AQ3; 4EHR; 4HNJ;

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