PROSITE entry PS50055

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PURL: https://purl.expasy.org/prosite/signature/PS50055

Direct ScanProsite submission

General information about the entry

Entry name [info]	TYR_PHOSPHATASE_PTP
Accession [info]	PS50055
Entry type [info]	MATRIX
Date [info]	01-NOV-1997 CREATED; 12-AUG-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00323
Associated ProRule [info]	PRU00160

Name and characterization of the entry

Description [info]

PTP type protein phosphatase domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=255;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=250;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.3013000; R2=0.0105123; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3465.4118652; R2=26.7058830; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=780; H_SCORE=24296; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=590; H_SCORE=19222; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='F';  M=-12,-27,-22,-32,-22, 27,-29,-20, 14,-25, 22, 12,-23,-21,-24,-20,-21, -9,  8,-11,  7,-22;
/M: SY='E';  M= -4, -4,-24, -1, 15,-14,-18, -8,-18,  2,-13,-11, -5,-12,  4, -1,  0, -4,-15,-17, -8, 10;
/M: SY='E';  M= -3, -1,-26,  1, 17,-24,-14, -3,-20,  8,-15, -8, -3,-10, 11,  4, -2, -6,-18,-24,-13, 14;
/M: SY='E';  M= -9, 10,-29, 18, 48,-32,-19,  0,-29, 10,-21,-17,  1, -3, 23,  1,  0,-10,-29,-28,-18, 35;
/M: SY='F';  M=-19,-26,-23,-33,-27, 61,-29,-10,  0,-24,  7,  0,-18,-30,-31,-17,-20,-10, -3, 15, 39,-26;
/M: SY='E';  M=-11,  3,-26,  5, 23,-25,-17, -3,-23, 13,-17, -9,  1,-10, 16,  8, -5,-10,-23,-25,-13, 19;
/M: SY='E';  M= -5, -5,-23, -6,  5,-14,-17, -6,-15,  2,-10, -5, -3,-11,  3,  5, -2, -3,-13,-24,-11,  3;
/M: SY='L';  M= -9,-29,-22,-33,-24,  7,-33,-24, 29,-29, 36, 19,-26,-27,-21,-23,-24, -8, 19,-21, -1,-24;
/M: SY='D';  M= -8,  1,-21,  2,  2,-22,-17, -8,-19,  0,-18,-11,  0,  1,  2, -3,  0, -1,-17,-27,-13,  1;
/M: SY='Q';  M= -4, -2,-22, -3,  3,-21,-14, -1,-17,  4,-16, -7,  2,-11,  9,  7,  3, -1,-15,-27,-12,  5;
/M:         M= -6,-10,-15,-12, -7,-10,-15,-11, -6, -8, -6, -2, -8,-17, -5, -8, -4, -4, -4,-24, -7, -7;
/M: SY='K';  M= -7, -4,-22, -7, -1,-13, -7,-10,-19,  2,-18,-10,  0,-13, -1,  1, -2, -4,-16,-22,-11, -1;
/I:         I=-5; MI=0; MD=-20; IM=0;
/M: SY='A';  M=  2, -4,-12, -5, -1, -8, -9, -6, -3, -5, -2, -3, -3, -6, -3, -6, -2, -2, -3,-12, -6, -3; D=-2;
/I:         DM=-20;
/M: SY='Q';  M= -7, -2,-21,  0,  2,-19,-13, -2,-13,  1,-12, -4, -2, -5,  4,  1, -1, -4,-12,-23,-10,  2; D=-2;
/I:         DM=-20;
/M: SY='B';  M= -7,  1,-23,  1, -1,-18,-11, -7,-12, -5,-13, -9,  0,-12,  1, -7, -1, -2,-12,-17, -9,  0; D=-2;
/I:         DM=-20;
/M:         M= -9, -6,-20, -7, -6, -5,-12, -7,-12, -9,-11, -8, -4,-20, -6, -7, -5, -7,-10,-15, -1, -7;
/M: SY='S';  M= -5,  3,-23,  5,  4,-23,-14, -9,-20, -1,-21,-15,  2,  6, -1, -5,  7,  7,-16,-31,-17,  0;
/M: SY='C';  M=-11,-15, 11,-20,-14, -4,-24,-13,-12,-13,-10, -6,-12,-19,-11,-11,-10, -6,-10,-16, -4,-13;
/M: SY='S';  M= -2, -2,-21, -3,  1,-15,-14, -6,-17,  2,-15, -9,  0,-14, -1,  2,  4,  2,-11,-26,-10,  0;
/M: SY='T';  M= -1, -6, -8,-10, -5,-11,-18,-11, -7,-13,-10, -8, -5,-16,-10,-14,  3,  7, -2,-28, -9, -8;
/M: SY='A';  M= 23, -5,-17, -8, -7,-23, 11,-15,-19,-11,-17,-14, -3,-13, -7,-16, 10, -3,-11,-24,-19, -7;
/M: SY='N';  M= -9,  6,-22,  4,  4,-18,-16, -1,-16,  2,-12, -7,  7,-16,  5,  1, -3, -6,-16,-27,-10,  4;
/M: SY='R';  M=-10,-13,-24,-15, -7, -3,-19, -8, -7, -1,  2,  0, -8,-20, -6,  3,-13, -8, -8,-19, -3, -7;
/M: SY='P';  M= -6, -7,-31, -2, 13,-27,-18,-10,-20, -1,-21,-14, -9, 32,  4, -8, -4, -8,-24,-28,-21,  6;
/M: SY='E';  M= -6,  0, -7, -1, 11,-23,-14, -5,-22,  0,-18,-13,  0,-15,  1, -2, -2, -6,-16,-30,-16,  5;
/M: SY='N';  M=-10, 34,-21, 16, -1,-18, -2, 12,-18, -1,-27,-16, 52,-20,  0,  0,  8, -1,-28,-37,-15, -1;
/M: SY='R';  M= -8,-10,-24,-13, -5,-16,-19, -6,-10, 11, -9,  3, -6,-17,  2, 15,-10, -8, -7,-21, -6, -4;
/M: SY='E';  M= -8,  4,-23,  5,  6,-21,-10, -3,-22,  2,-20,-12,  4, -8, -1, -1, -1, -6,-18,-28,-14,  2;
/M: SY='K';  M=-12, -3,-30, -3,  7,-25,-20, -7,-27, 42,-25, -7, -2,-12,  9, 32,-11,-10,-18,-19, -7,  7;
/M: SY='N';  M= -8, 34,-16, 16, -2,-20, -2,  6,-19, -2,-28,-19, 51,-20, -2, -3,  9,  0,-26,-39,-20, -2;
/M: SY='R';  M=-19,-10,-30,-10,  1,-21,-20,  0,-29, 28,-20,-10,  0,-17, 12, 65,-10,-10,-21,-20,-10,  2;
/M: SY='Y';  M=-12,-12,-23,-15,-15, 14,-22,  6, -3,-12, -4, -3,-10,-24,-10,-12, -9, -4, -7,  3, 38,-15;
/M: SY='K';  M= -2, -9,-23,-10, -3,-19,-14,-12,-13,  4,-16, -7, -6, -2, -2,  3,  1,  0, -8,-26,-15, -4;
/I:         I=-6; MI=-32; MD=-32; IM=-32;
/M: SY='B';  M=-11, 29,-20, 27,  6,-25, -8,  6,-24, -2,-25,-17, 28,-15,  1, -5,  6, -1,-24,-36,-16,  3; D=-6;
/I:         I=-6; MI=-32; IM=-32; DM=-32;
/M: SY='I';  M= -6,-28,-19,-34,-28,  0,-34,-28, 35,-25, 14, 14,-23,-21,-23,-25,-15, -5, 31,-24, -4,-28;
/M: SY='L';  M= -8,-24,-21,-26,-17,  3,-28,-20, 16,-21, 21, 11,-22,-18,-17,-18,-18, -6, 12,-21, -2,-18;
/M: SY='P';  M= -5,-20,-25,-14, -5,-26,-20,-21,-16,-13,-23,-16,-19, 63,-12,-21, -9, -9,-22,-30,-27,-12;
/M: SY='Y';  M=-15,-18,-27,-20,-19, 25,-26,  5,  0,-13, -1, -2,-15,-19,-15,-13,-16, -8, -7, 11, 47,-20;
/I:         I=-5; MI=0; IM=0; DM=-20; MD=-20;
/M: SY='D';  M=-17, 36,-30, 52, 29,-36,-13, -1,-36,  2,-27,-27, 14, -3,  5, -8,  0,-10,-30,-37,-20, 17;
/M: SY='H';  M=-12, -5,-25, -6, -1, -9,-18, 34,-22, -5,-15, -6,  1,-18,  3,  3, -6,-11,-20,-20,  7, -1;
/M: SY='S';  M=  6,  8, -9,  1, -3,-19, -5, -8,-18, -7,-25,-17, 17,-13, -3, -8, 25, 17,-12,-36,-18, -3;
/M: SY='R';  M=-19,-12,-29,-12, -2,-18,-21, -2,-26, 25,-15, -8, -2,-21,  8, 63,-11,-10,-17,-20, -9, -2;
/M: SY='V';  M= -1,-29,-13,-30,-28,  0,-30,-29, 28,-20,  8,  9,-29,-23,-29,-20,-11, -1, 44,-29,-10,-29;
/M: SY='K';  M=-11,-10,-20,-10, -1,-18,-19, -6,-14,  6,-15, -6, -7, -9, -1,  2,-10,-11,-12,-23, -8, -3;
/M: SY='L';  M=-10,-29,-21,-30,-21,  8,-28,-21, 21,-30, 44, 19,-28,-29,-20,-21,-28,-10, 11,-20, -1,-21;
/M: SY='S';  M= -1, -2,-22, -5, -2,-23, -9, -7,-17,  1,-19,-10,  1, -6,  4, -1,  5,  4,-14,-27,-14,  0;
/I:         I=-5; MI=0; MD=-20; IM=0;
/M: SY='P';  M= -5, -6,-25, -4, -2,-21, -8,-11,-16, -6,-17,-11, -4, 11, -5, -7,  0, -2,-15,-28,-18, -5; D=-3;
/I:         DM=-20;
/M: SY='L';  M= -7,-13,-25,-14, -7,-13,-18,-15,  0, -7,  1,  1,-11,-14, -7, -7,-10, -6, -1,-24,-10, -8;
/M: SY='D';  M= -8,  8,-27, 13, 13,-27,-13, -2,-25,  1,-23,-17,  4,  5,  4, -3,  2, -3,-23,-30,-17,  7;
/M: SY='G';  M= -3,  1,-27,  3, -2,-27, 25,-12,-30,-10,-26,-18,  4, -8, -8,-13,  4, -9,-24,-27,-24, -6;
/M: SY='E';  M= -9,  7,-23, 10, 12,-21,-15, -2,-20,  0,-18,-13,  3, -9,  2, -3,  0, -5,-17,-28,-12,  6;
/I:         MD=-20;
/M: SY='E';  M= -7,  4,-22,  9, 14,-18,-14, -6,-16,  0,-15,-12,  0,  5,  3, -6, -1, -5,-16,-23,-13,  8; D=-1;
/I:         I=-4; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='G';  M= -4,  3,-19,  2, -6,-19, 13, -8,-20,-10,-16,-13,  6,-13, -9,-10,  1, -4,-16,-24,-16, -8; D=-1;
/I:         DM=-20;
/M: SY='S';  M=  5,  0,-10, -2, -4,-14, -5,-11,-14, -9,-18,-13,  4,-11, -4,-10, 22, 18, -6,-30,-13, -4; D=-1;
/I:         DM=-20;
/M: SY='D';  M=-13, 32,-24, 42, 11,-29, -7,  0,-31, -1,-25,-23, 17,-11, -1, -6,  4, -3,-23,-34,-16,  5; D=-1;
/I:         DM=-20;
/M: SY='Y';  M=-20,-21,-29,-22,-21, 33,-30, 16,  1,-12,  1,  1,-20,-30,-12,-11,-20,-10, -8, 27, 74,-21;
/M: SY='I';  M=-10,-29,-29,-38,-28,  0,-38,-27, 44,-28, 18, 18,-21,-18,-19,-28,-19, -9, 27,-19,  1,-28;
/M: SY='N';  M=-10, 37,-17, 18, -1,-20, -1, 10,-20, -1,-30,-20, 56,-20,  0, -1, 10,  0,-29,-40,-19, -1;
/M: SY='A';  M= 46,-11,-11,-21,-11,-19, -1,-20, -8,-11, -8, -7,-10,-11,-10,-20,  8, -1,  1,-20,-19,-11;
/M: SY='S';  M=  5, 12,-14,  5,  1,-20, -1, -4,-19, -6,-28,-19, 24,-13, -1, -7, 26, 11,-15,-38,-20,  0;
/I:         I=-4; MI=0; MD=-15; IM=0;
/M: SY='Y';  M=-14,-18,-24,-21,-16, 22,-25, -6,  0,-10,  3,  0,-15,-23,-15, -9,-16, -8, -4, 10, 27,-16; D=0;
/I:         DM=-15;
/M: SY='I';  M= -8,-24,-18,-29,-23,  0,-29,-21, 26,-20, 12, 14,-19,-21,-18,-17,-15, -6, 22,-21, -3,-23; D=0;
/I:         DM=-15;
/M: SY='D';  M=-11, 10,-26, 15,  3,-23,-10, -5,-20, -2,-19,-10,  3, -2, -3, -7, -3, -5,-16,-28,-14, -1; D=0;
/I:         DM=-15;
/M: SY='G';  M= -1,-10,-25,-11,-15,-20, 27,-14,-19,-15,-18,-10, -3,-17,-13,-16,  0,-10,-14,-21,-16,-15; D=0;
/I:         DM=-15;
/M: SY='Y';  M=-11,-11,-25,-10,-10, 10,-18,  2, -8,-11, -7, -6,-10,-18,-11,-11, -9, -7,-10, -1, 28,-12; D=0;
/I:         DM=-15;
/M: SY='R';  M=-10, -2,-27, -3,  0,-16,-11, -2,-20,  4,-20,-12,  1,-10,  1,  6, -4, -5,-19,-11, -2, -1; D=0;
/I:         DM=-15;
/M: SY='R';  M= -6, -5,-24, -6,  5,-18,-12, -6,-19,  7,-16, -8, -2,-10,  8, 10, -2, -7,-17,-21,-11,  5; D=0;
/I:         DM=-15;
/M: SY='P';  M= -7, -4,-27, -3,  8,-23,-16, -7,-19,  4,-19,-10, -3,  9,  6,  1, -1, -4,-19,-26,-15,  6; D=0;
/I:         DM=-15;
/M: SY='K';  M= -8,  4,-26,  0,  3,-20,-11, -2,-24, 16,-24,-13, 10,-13,  4, 16, -2, -7,-20,-21,-12,  3;
/M: SY='A';  M=  8, -2,-19, -4,  4,-19,-13, -7,-15,  1,-15, -9, -3,-12,  0, -4,  5,  2, -8,-25,-11,  2;
/M: SY='Y';  M=-18,-23,-26,-27,-23, 41,-29,  4,  2,-16,  5,  4,-20,-28,-18,-13,-19, -8, -5, 17, 54,-22;
/M: SY='I';  M=-10,-30,-29,-39,-30,  0,-39,-30, 49,-29, 19, 19,-20,-20,-20,-29,-19, -9, 31,-20,  0,-30;
/M: SY='A';  M= 29,-17, -6,-24,-16,-11,-10,-22,  0,-16,  0, -3,-16,-17,-16,-21,  0, -3,  7,-22,-15,-16;
/M: SY='T';  M= 11, -4, -2,-13,-11,-14,-15,-20,-12,-11,-11,-11, -3,-12,-11,-14, 16, 33, -1,-29,-14,-11;
/M: SY='Q';  M=-10,  0,-30,  0, 21,-40,-20, 10,-20, 10,-20, -1,  0, -9, 59, 10,  0,-10,-30,-20,-10, 40;
/I:         I=-6; MI=0; IM=0; DM=-20; MD=-20;
/M: SY='G';  M=  3,-11,-27,-12,-17,-23, 40,-11,-29,-18,-20,-13, -4,-20,-16,-17, -3,-15,-21,-17,-19,-17;
/M: SY='P';  M=-10,-19,-32,-10,  0,-29,-20,-20,-21,-11,-29,-20,-19, 80,-10,-20, -9, -9,-29,-31,-30,-10;
/M: SY='L';  M= -9,-22,-21,-24,-16,  6,-27,-16, 11,-19, 30, 16,-21,-25,-14,-13,-22, -8,  5,-20, -1,-15;
/M: SY='P';  M= -3, -8,-28, -5,  4,-24,-17, -9,-16, -2,-18,-10, -7, 20,  3, -7, -2, -6,-18,-28,-18,  2;
/M: SY='N';  M= -7, 16,-23, 14, 14,-24, -9, 13,-25,  0,-25,-17, 19,-12,  6, -2,  9, -1,-24,-34,-13,  9;
/M: SY='T';  M= -1,  0,-12, -9, -8,-10,-18,-14,-11,-10,-12,-10,  2,-11, -7, -9, 19, 41, -3,-30, -9, -8;
/I:         I=-6; MI=0; IM=0; DM=-20; MD=-20;
/M: SY='V';  M= -6,-24, -5,-29,-22,  0,-30,-24, 17,-20,  7,  6,-21,-25,-20,-18,-12, -3, 20,-23, -6,-22;
/M: SY='E';  M= -2,  5,-22,  7,  8,-23, -4, -5,-23,  0,-19,-14,  3,-13, -1, -6,  0, -7,-18,-26,-13,  3;
/M: SY='D';  M=-16, 37,-27, 52, 16,-36,-12,  4,-34, -2,-27,-24, 15,-11,  2, -9,  1, -9,-26,-38,-17,  8;
/M: SY='F';  M=-20,-30,-20,-40,-30, 80,-30,-20,  0,-30, 10,  0,-20,-30,-40,-20,-20,-10,  0, 10, 30,-30;
/M: SY='W';  M=-20,-40,-50,-40,-30, 10,-20,-29,-20,-20,-20,-20,-40,-30,-20,-20,-40,-30,-30,148, 31,-20;
/M: SY='R';  M=-15, -8,-28, -8,  4,-20,-21,  1,-22, 17,-14, -5, -3,-17, 17, 36, -8, -8,-19,-18, -6,  8;
/M: SY='M';  M= -8,-20,-17,-29,-20,  0,-21, -4, 18,-12, 20, 52,-20,-21, -3,-11,-19, -8, 11,-21, -1,-12;
/M: SY='V';  M= -4,-29,-14,-33,-29, -1,-33,-29, 34,-24, 14, 13,-25,-26,-25,-24,-14, -4, 37,-26, -6,-29;
/M: SY='W';  M=-16,-33,-39,-34,-26, 14,-21,-20,-14,-19,-12,-13,-31,-28,-19,-18,-29,-20,-20, 96, 27,-19;
/M: SY='E';  M=-10, 12,-29, 19, 38,-33,-18,  5,-27,  7,-20,-15,  3, -6, 26,  1,  0,-10,-29,-28,-16, 32;
/M: SY='Q';  M=-12,  3,-29,  2, 16,-25,-18, 17,-22,  5,-19, -8,  5,-13, 25,  6, -2,-10,-26,-18, -3, 20;
/M: SY='N';  M= -8,  9,-24,  4,  3,-26, -4,  0,-26, 15,-27,-13, 17,-15,  6, 11,  0, -7,-23,-28,-15,  4;
/I:         I=-6; MI=0; MD=-25; IM=0;
/M: SY='S';  M=  3,-12,  5,-16,-15,-13,-17,-18, -3,-17,-11, -8, -7,-18,-14,-17,  9,  7,  6,-34,-16,-15; D=-5;
/I:         DM=-25;
/M: SY='S';  M= -1, -5,-16, -9, -3,-19,-13, -5,-16, -1,-15, -9, -1,-10,  1,  1,  3,  3,-12,-27,-12, -2;
/M: SY='V';  M=  0,-19,-14,-24,-21, -4,-23,-22, 14,-18,  5,  5,-16,-21,-18,-17, -4,  5, 19,-26, -8,-20;
/M: SY='I';  M= -8,-30,-25,-36,-29,  2,-37,-27, 42,-27, 18, 17,-23,-23,-22,-26,-18, -8, 32,-20,  1,-29;
/M: SY='V';  M=  1,-29,-12,-30,-28,  2,-29,-28, 27,-21, 13, 10,-28,-28,-28,-20,-11, -2, 42,-27, -8,-28;
/M: SY='M';  M= -9,-18,-18,-28,-20, -1,-20, -3, 19,-12, 16, 50,-17,-20, -3,-11,-17, -9, 10,-22, -2,-11;
/M: SY='L';  M= -5,-27,-19,-29,-21,  6,-28,-21, 20,-25, 32, 17,-25,-25,-19,-20,-21, -5, 15,-21, -2,-21;
/M: SY='T';  M=  0,  0,-10, -9,-10,-14,-14,-17,-12,-11,-14,-12,  3, -6,-10,-12, 14, 30, -5,-31,-15,-10;
/M: SY='R';  M=-10,  9,-26,  8,  9,-25,-12, -3,-25, 14,-23,-13, 10,-10,  7, 15,  0, -4,-21,-28,-15,  7;
/I:         MD=-20;
/M: SY='L';  M= -8,-14, -9,-14, -6, -8,-23,-17,  1,-18, 12,  1,-16,-18,-12,-17,-14, -7,  0,-27,-10, -9; D=-1;
/I:         MD=-20;
/M: SY='E';  M=-10, -5,-22, -4,  2, -9,-21,-10, -7, -1, -7, -3, -7,-17, -4, -2, -7, -6, -2,-23, -7, -1; D=-1;
/I:         MD=-20;
/M: SY='E';  M=-10, 11,-28, 19, 49,-28,-18,  0,-27,  6,-18,-18,  2, -2, 15, -2,  0, -9,-27,-30,-19, 32; D=-1;
/I:         I=-5; MI=0; IM=0; DM=-20;
/M: SY='E';  M= -7, -2,-22, -3, 10,-19,-21,-10,-10,  3,-12, -8, -2,-12,  2,  1, -3, -4, -7,-28,-14,  5;
/M: SY='K';  M= -8, -1,-27, -2,  5,-26,-17, -9,-22, 30,-22, -7, -1,-12,  7, 17, -8, -7,-15,-22,-10,  5;
/M: SY='C';  M= -8,-18, 91,-26,-23,-17,-27,-27,-26,-26,-17,-18,-18,-35,-25,-26, -7, -7,-10,-43,-25,-24;
/M: SY='D';  M=  0,  2,-22,  4,  3,-18,-14,  2,-19, -6,-16,-11, -2, -9,  0, -8,  0, -4,-14,-25, -8,  0;
/M: SY='Q';  M=-11, -4,-28, -3, 10,-28,-20,  5,-18, 12,-17, -3, -1,-13, 28, 16, -4, -9,-20,-22, -8, 18;
/M: SY='Y';  M=-19,-20,-29,-21,-20, 29,-30, 18,  1,-12,  2,  1,-20,-30,-11,-10,-20,-10, -9, 25, 72,-20;
/M: SY='W';  M=-20,-38,-47,-39,-29, 15,-21,-28,-17,-20,-16,-17,-38,-30,-21,-20,-38,-28,-27,133, 30,-21;
/M: SY='P';  M= -8,-16,-38, -9, -1,-29,-15,-18,-21,-10,-29,-20,-15, 76, -9,-19, -8, -9,-29,-30,-29, -9;
/I:         MD=-15;
/M: SY='D';  M= -4, 10,-20, 13,  9,-19,-11, -5,-19, -3,-14,-14,  6,-11,  0, -5,  4, -1,-15,-28,-14,  4; D=-1;
/I:         MD=-15;
/M: SY='E';  M= -5,  1,-15,  2,  6,-11, -9, -3,-10,  1, -8, -6,  0, -4,  1, -2, -2, -4,-10,-15, -7,  3; D=-1;
/I:         I=-4; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='E';  M= -8,  7,-26, 10, 16,-24, -3, -1,-27,  3,-22,-16,  6,-10,  4,  1,  1, -7,-24,-26,-15, 10; D=-1;
/I:         DM=-15;
/M: SY='G';  M= -4,  2,-25,  4,  4,-25, 11,-10,-26, -4,-21,-13,  2,-13, -2, -4,  2, -5,-20,-26,-19,  1; D=-1;
/I:         DM=-15;
/M: SY='T';  M= -2, -8,-17, -9, -5,-13,-14,-12,-13, -3,-15, -9, -5, -3, -4, -5,  5,  7, -9,-24, -9, -5; D=-1;
/I:         DM=-15;
/M: SY='Q';  M= -4,-11,-20,-12,  1,-13,-20,-10, -5, -3, -5,  0,-10,-16,  2, -6, -6, -7, -4,-21, -9,  1;
/I:         DM=-15;
/M: SY='T';  M= -5,  1,-20, -2,  1,-14,-17, -8,-13, -2,-12,-10,  2,-13,  0,  0,  4,  9, -9,-25, -8,  0; D=-6;
/I:         DM=-15;
/M: SY='Y';  M=-17,-15,-21,-18,-16, 24,-26, 15, -7,-14, -4, -3,-12,-25,-13,-11,-13, -7,-10,  6, 45,-17;
/M: SY='G';  M= -3, -4,-28, -3, -8,-29, 40,-13,-34,-11,-27,-18,  1,-14, -9,-12,  1,-14,-27,-23,-24, -9;
/M: SY='D';  M= -8,  6,-23,  8,  0,-20,-10, -1,-21, -2,-20,-13,  4, -7, -3, -4, -1, -5,-17,-27,-10, -3;
/M: SY='F';  M=-13,-28,-24,-34,-26, 24,-32,-17, 22,-25, 19, 16,-22,-26,-22,-21,-21, -9, 14, -8, 15,-25;
/M: SY='R';  M= -8, -7,-22, -8,  3,-13,-21, -7,-13,  3,-12, -6, -5,-13,  4,  5, -1,  1,-10,-23, -8,  3;
/M: SY='V';  M= -3,-30,-16,-32,-29,  1,-32,-29, 34,-23, 15, 13,-27,-27,-27,-23,-14, -3, 42,-27, -7,-29;
/M: SY='T';  M= -6,  6,-20,  3,  9,-20,-16, -3,-19,  3,-17,-12,  6,-11,  5,  1,  6, 10,-16,-29,-12,  7;
/M: SY='L';  M= -7,-14, -7,-20,-17, -1,-23,-15,  5,-20, 10,  5, -9,-20,-15,-17,-13, -5,  2,-26, -7,-17;
/M: SY='M';  M= -6,-14,-20,-17,-10,-11,-23,-12,  4, -4,  1,  7,-12,-19, -4, -3, -8, -3,  6,-25, -8, -8;
/M: SY='D';  M= -2, 10,-22, 11,  7,-24, -7, -4,-25,  5,-25,-17, 10,-12,  2,  2,  8, -2,-19,-30,-16,  4;
/I:         MD=-18;
/M: SY='E';  M= -5, -3,-17, -1, 14,-17,-20, -8,-11, -1,-11, -8, -6,-12,  0, -5, -1,  1, -6,-27,-11,  6; D=-1;
/I:         MD=-18;
/M: SY='E';  M=-10,  6,-24,  8, 10,-19,-18,  3,-16,  1,-16,-10,  3,-13,  3, -3, -1, -2,-14,-24, -6,  5; D=-1;
/I:         I=-4; MI=0; IM=0; DM=-18;
/M: SY='B';  M= -7,  4,-21,  4,  4,-20,-14, -5,-16, -2,-15,-10,  2,-13, -1, -5, -2, -5,-13,-23,-13,  1;
/M:         M= -7, -8, -8,-10, -6, -8,-20, -6,-10, -9, -5, -2, -8,-16, -7,-10, -6, -4, -9,-23, -3, -7;
/M: SY='E';  M= -2,  1,-20,  4,  6,-25,-10, -8,-21, -3,-22,-16, -1,  4, -2, -8,  4, -2,-17,-31,-19,  1;
/M: SY='D';  M= -6, 11,-21, 15, 13,-25,-10,  0,-25, -2,-20,-16,  5,-11,  4, -6,  1, -5,-21,-27,-11,  8;
/M: SY='Y';  M=-17,-23,-26,-26,-22, 28,-29,  1,  3,-16,  3,  2,-21,-28,-16,-14,-20,-10, -4, 23, 49,-21;
/M: SY='T';  M= -3,-13,-12,-20,-16, -8,-24,-18,  5,-14, -1,  0,-10,-16,-13,-14,  0, 13,  7,-27, -8,-16;
/M: SY='I';  M= -7,-21,-19,-25,-19, -2,-27,-19, 17,-17, 12, 10,-17,-23,-15,-12,-11, -3, 17,-24, -5,-19;
/M: SY='R';  M=-16, -7,-28, -7,  3,-21,-20,  4,-28, 22,-20,-10,  1,-17, 10, 49, -5, -4,-19,-23, -9,  3;
/M: SY='E';  M= -6,  2,-23,  2,  6,-20,-17, -6,-14, -1,-13, -8,  0,-13,  2, -4,  1,  4,-10,-27,-12,  4;
/M: SY='F';  M=-15,-29,-20,-36,-26, 46,-30,-20, 11,-29, 24, 11,-23,-29,-30,-20,-23,-10,  7, -4, 16,-26;
/M: SY='K';  M= -7, -6,-21, -7,  2,-16,-20, -6,-14,  5,-12, -6, -4,-10,  3,  4, -5, -4,-12,-22, -5,  1;
/M: SY='L';  M= -7,-26,-20,-28,-21,  3,-30,-22, 24,-24, 27, 15,-25,-26,-20,-21,-20, -7, 21,-22, -2,-21;
/M: SY='E';  M= -7, -1,-19, -2,  7,-19,-14, -3,-21,  4,-18,-10,  0,-13,  6,  3,  3,  3,-17,-24, -9,  6;
/M: SY='N';  M= -9,  9,-22,  4, -1,-18,-13,  8,-20,  5,-21,-11, 14,-15,  0,  4, -2, -6,-19,-26, -7, -1;
/M: SY='T';  M=  0, -8,-17,-12, -8,-13,-12,-13, -6, -9, -6, -4, -5,-15, -6, -8,  2,  5, -2,-27,-12, -8;
/M: SY='Q';  M= -7,  5,-26,  6,  7,-28, -3, -5,-25,  4,-22,-14,  6, -8,  8,  2,  0, -6,-23,-27,-17,  7;
/I:         MD=-17;
/M: SY='E';  M= -8,  5,-23,  7, 12,-21,-14, -3,-19,  1,-18,-12,  2, -4,  5, -1,  3,  1,-16,-27,-12,  7; D=-1;
/I:         MD=-17;
/M: SY='D';  M= -6,  3,-22,  4,  3,-23, -3, -6,-21,  2,-20,-11,  4, -5,  3, -1,  2, -3,-18,-25,-15,  3; D=-1;
/I:         MD=-17;
/M: SY='E';  M= -6,  2,-20,  4, 13,-18,-12, -2,-15,  5,-14, -9,  1, -6, 10,  0, -1, -5,-15,-18, -7, 11; D=-1;
/I:         MD=-17;
/M: SY='T';  M= -2, -2,-14, -2,  0,-14, -9,-10,-10, -2,-12, -8, -2, -4, -3, -3,  4,  5, -5,-21,-11, -2; D=-1;
/I:         I=-4; MI=0; IM=0; DM=-17;
/M: SY='R';  M=-16,-11,-25,-11, -2,-16,-19,  1,-22, 16,-12, -5, -4,-20,  6, 40,-10, -9,-16,-21, -7, -1;
/M: SY='E';  M= -8, -3,-22, -3,  6,-16,-20, -7,-11, -2, -9, -6, -4,-12,  1, -3,  0,  5, -8,-26, -9,  3;
/M: SY='V';  M= -4,-28,-14,-32,-28,  0,-32,-28, 31,-24, 16, 13,-25,-26,-25,-22,-14, -2, 35,-26, -6,-28;
/M: SY='R';  M= -9,-12,-19,-15, -8, -8,-21, -5,-13,  2, -9, -5, -9,-19, -3,  9, -6,  1, -9,-10,  2, -7;
/M: SY='H';  M=-13, -1,-29, -1, 11,-29,-20, 38,-21,  1,-17,  1,  2,-14, 34,  4, -5,-13,-26,-24,  0, 21;
/M: SY='F';  M=-14,-26,-23,-32,-25, 43,-29,-10,  7,-23, 13,  6,-21,-28,-26,-18,-20, -9,  2,  6, 31,-25;
/M: SY='H';  M=-15, -2,-30, -2,  6,-25,-20, 47,-23, -3,-18, -2,  3,-14, 26,  2, -7,-15,-28,-18,  6, 14;
/M: SY='F';  M=-18,-24,-13,-29,-25, 44,-30, -1, -2,-21,  4, -1,-20,-30,-25,-16,-19,-10, -4, 10, 42,-25;
/M: SY='T';  M= -5, -6,-19,-11, -9,-11,-21, -4, -6, -9, -5, -2, -5,-10, -7, -8,  2, 15, -4,-26, -5, -9;
/M: SY='S';  M=  7,  4,-18,  0, -1,-21, -1,-11,-18, -4,-19,-13,  7,-13, -3, -8, 11,  6,-13,-29,-18, -2;
/I:         I=-5; MI=0; IM=0; DM=-20; MD=-20;
/M: SY='W';  M=-20,-40,-50,-40,-30, 10,-20,-30,-20,-20,-20,-20,-40,-30,-20,-20,-40,-30,-30,150, 30,-20;
/M: SY='P';  M= -8,-16,-36, -9,  1,-28,-19,-17,-20, -5,-27,-17,-15, 66, -6,-13, -8, -9,-27,-28,-26, -6;
/M: SY='D';  M=-15, 32,-29, 45, 17,-33,-10,  2,-32, -1,-25,-23, 14,-11,  2, -9, -1, -9,-26,-33,-17,  9;
/M: SY='H';  M=-13, -7,-23, -8, -2, -7,-20, 33,-17,-10,-10, -1, -3,-16,  0, -6,-10,-13,-16,-22,  7, -3;
/I:         I=-10; MI=0; IM=0; MD=-20; DM=-20;
/M: SY='G';  M= -4,  0,-28,  2, -5,-30, 33,-12,-34, -6,-28,-18,  4,-15, -5, -8,  2,-13,-27,-25,-23, -5;
/M: SY='V';  M=  0,-20,-10,-23,-21, -5,-24,-22, 13,-17,  3,  3,-18,-23,-19,-17, -4,  4, 23,-27, -8,-20;
/M: SY='P';  M=-10,-20,-39,-10, -1,-28,-20,-20,-18,-11,-26,-18,-20, 83,-10,-20,-11,-10,-28,-30,-28,-10;
/M: SY='E';  M= -4,  2,-24,  5, 14,-20,-14, -7,-18, -1,-16,-13, -1, -5,  1, -7,  2, -3,-15,-27,-13,  7;
/I:         MD=-19;
/M: SY='S';  M= -3,  5,-20,  6,  2,-18,-12,  0,-18, -5,-20,-14,  5,-12, -1, -7, 12,  6,-12,-29, -7,  0; D=-4;
/I:         I=-6; MI=0; IM=0; DM=-19;
/M: SY='G';  M= -3, -3,-26,  0, -4,-24,  6,-12,-24,-10,-24,-17, -1,  6, -8,-13,  4, -5,-21,-26,-20, -7;
/M: SY='L';  M=-11,-27,-22,-33,-24, 20,-31,-22, 20,-25, 23, 15,-23,-24,-23,-20,-21, -7, 14,-14,  5,-24;
/M: SY='L';  M= -9,-29,-21,-32,-23, 10,-31,-23, 25,-27, 33, 16,-26,-26,-22,-21,-23, -9, 17,-19,  0,-23;
/M: SY='D';  M= -5, 12,-24, 13, 12,-28,-12, -2,-26, 10,-23,-15,  9,-11, 10,  7,  4, -3,-21,-29,-15, 11;
/M: SY='F';  M=-13,-27,-18,-33,-25, 41,-28,-17,  8,-25, 19, 11,-22,-27,-27,-18,-20, -7,  6, -5, 16,-24;
/M: SY='I';  M= -8,-25,-22,-29,-21, -1,-30,-15, 21,-20, 17, 13,-19,-24,-16,-13,-17, -8, 17,-22, -2,-21;
/M: SY='R';  M= -8, -3,-24, -4,  3,-16,-13,  0,-23,  9,-17,-10,  1,-16,  4, 18, -3, -7,-18,-21, -8,  2;
/M: SY='Q';  M= -7, -4,-25, -3,  6,-19,-19, -2,-15,  9,-14, -4, -4,-14, 10,  8, -4, -6,-13,-21, -5,  7;
/M: SY='V';  M=  0,-25,-12,-28,-25,  1,-27,-25, 21,-19,  8, 10,-23,-26,-23,-19, -9, -1, 32,-26, -7,-24;
/M: SY='R';  M=-13,  1,-27, -2,  3,-19,-17,  5,-21, 14,-18, -7,  6,-15,  7, 21, -6, -8,-19,-24, -8,  4;
/M: SY='E';  M= -5,  7,-23,  7, 13,-26,-14,  3,-24,  9,-23,-12,  7,-11, 12,  4,  4, -2,-20,-28,-12, 12;
/M:         M= -5,-10,-11,-12, -5,-10,-20, -9,-11, -7, -9, -7, -9,-18, -4, -7, -3, -2, -7,-16, -4, -5;
/M: SY='Q';  M= -7, -4,-24, -6, -3,-18,-10, -2,-15,  2,-14, -6,  1,-16,  5,  4, -4, -7,-15,-21, -6,  0;
/I:         MD=-18;
/M: SY='E';  M= -5, -2,-23, -1,  7,-22,-15, -9,-18,  0,-18,-12, -2,  3,  4,  0,  0, -3,-17,-27,-16,  4; D=-1;
/I:         MD=-18;
/M: SY='Q';  M= -6, -2,-19, -3,  0,-19,-10, -2,-17, -3,-14, -8,  0,-10,  4, -2,  0, -3,-15,-25,-11,  1; D=-1;
/I:         MD=-18;
/M: SY='S';  M= -2, -4,-19, -6, -3,-11, -9, -9,-13, -7,-13, -9, -1,-13, -4, -5,  4,  0,-10,-23, -9, -4; D=-1;
/I:         MD=-18;
/M: SY='N';  M=  1,  0,-19, -1, -2,-20,  1,-10,-17, -5,-18,-12,  2, -2, -4, -9,  2, -5,-15,-25,-17, -4; D=-1;
/I:         MD=-18;
/M: SY='G';  M=  1,  1,-17,  1, -1,-22, 10, -7,-22, -7,-20,-14,  3, -8, -3,-10,  4, -6,-17,-24,-17, -3; D=-1;
/I:         MD=-18;
/M: SY='H';  M= -2,  1,-12,  2,  2,-11, -3,  5,-12, -1,-10, -6,  2, -5,  0, -1,  1, -3,-10,-14, -5,  1; D=-1;
/I:         I=-4; MI=0; IM=0; DM=-18;
/M: SY='P';  M= -7,-16,-36, -9, -2,-28,-15,-19,-20,-10,-28,-19,-15, 71,-10,-18, -6, -7,-27,-30,-28,-10;
/M: SY='I';  M= -6,-24,-18,-32,-25, -1,-32,-25, 30,-23, 14, 16,-20,-20,-19,-23,-13,  0, 24,-24, -4,-24;
/M: SY='V';  M= -4,-26, -9,-30,-26, -1,-30,-26, 24,-23, 13, 11,-23,-26,-23,-22,-12, -1, 28,-27, -7,-26;
/M: SY='V';  M= -2,-29,-12,-31,-29,  0,-31,-29, 31,-21, 12, 11,-28,-28,-28,-21,-11, -1, 44,-28, -9,-29;
/M: SY='H';  M=-17, -4,-27, -5, -4,-17,-21, 79,-21,-11,-15,  4,  4,-21,  6, -3,-10,-17,-19,-29, 15, -3;
/M: SY='C';  M= -8,-14, 95,-21,-23,-21,-25,-26,-29,-26,-22,-21,-14,-34,-24,-26, -3, -6,-11,-48,-28,-24;
/M: SY='S';  M=  5, -3,-12, -4, -1,-17, -6, -8,-16, -9,-21,-14,  5,-13, -1, -8, 24, 11,-10,-33,-16, -2;
/M: SY='A';  M= 26, -1,-15, -8, -8,-14, -6,-10,-13, -9,-12,-11, -1,-13, -9,-16,  6,  0, -7,-20,-10, -8;
/I:         I=-6; MI=0; IM=0; DM=-20; MD=-20;
/M: SY='G';  M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='V';  M=  3,-22,  0,-27,-24, -9,-20,-26, 13,-21,  0,  1,-18,-24,-22,-22, -5, -2, 20,-29,-13,-24;
/M: SY='G';  M=  0, -9,-28, -8,-15,-29, 54,-18,-35,-17,-27,-18, -1,-19,-14,-18,  2,-16,-25,-22,-27,-15;
/M: SY='R';  M=-18, -8,-29, -9,  2,-22,-20, -1,-28, 27,-20,-10,  0,-17, 12, 59, -8, -8,-20,-21,-10,  3;
/M: SY='T';  M= 10, -3, -6,-11, -9,-14,-13,-19,-12,-11,-14,-12, -1,-11, -9,-12, 21, 33, -1,-31,-14, -9;
/M: SY='G';  M=  1,-11,-20,-12,-20,-28, 59,-21,-38,-20,-28,-20, -2,-21,-20,-20,  0,-18,-27,-20,-29,-20;
/M: SY='T';  M=  0,-10,  3,-18,-16, -9,-22,-22, -2,-15, -5, -4, -9,-18,-15,-15,  8, 25,  8,-32,-12,-16;
/M: SY='F';  M=-17,-28,-21,-35,-27, 55,-30,-15,  6,-26, 14,  5,-21,-29,-31,-19,-20, -9,  3,  5, 28,-27;
/M: SY='I';  M= -7,-26, 15,-34,-28, -5,-33,-28, 20,-28,  9,  7,-21,-27,-23,-27,-15, -8, 18,-30,-10,-28;
/M: SY='A';  M= 18,-14, -9,-20,-16,-12, -7,-22, -3,-15, -3, -5,-13,-18,-16,-18,  4,  6,  7,-25,-16,-16;
/M: SY='I';  M= -1,-25,-21,-30,-22, -1,-26,-23, 23,-25, 22, 14,-21,-22,-18,-22,-16, -5, 16,-22, -5,-22;
/M: SY='D';  M=-12, 22,-22, 30,  9,-22,-12, -5,-25, -6,-19,-19,  9,-14, -4,-10,  2, -3,-18,-33,-15,  2;
/M: SY='I';  M= -1,-12,-18,-19,-14, -7,-22,-14,  6,-13, -3,  1, -7,-17, -8,-11,  0,  6,  4,-22, -3,-13;
/M: SY='L';  M=  0,-21, -2,-28,-21, -4,-22,-19, 11,-21, 14, 14,-19,-24,-17,-20,-14, -6, 11,-25, -9,-20;
/M: SY='L';  M= -8,-27,-11,-31,-23,  3,-29,-21, 19,-26, 30, 19,-26,-27,-19,-21,-23, -9, 13,-19, -3,-21;
/M: SY='E';  M= -6,  4,-21,  5, 15,-23,-15,  1,-18,  0,-15, -9,  2,-13, 11, -2,  0, -6,-18,-28,-12, 12;
/M: SY='Q';  M=-11, -8,-22, -9,  1,-20,-19,  2,-13,  3, -8,  1, -4,-18, 15, 11, -7, -8,-15,-23, -8,  7;
/M: SY='L';  M= -6,-25,-21,-30,-21,  5,-27,-19, 21,-23, 25, 22,-23,-21,-16,-20,-19, -6, 14,-20, -2,-20;
/M: SY='E';  M=-10,  7,-27, 10, 21,-27,-17, -1,-24, 13,-20,-13,  4,-10, 12, 10, -1, -6,-21,-28,-14, 16;
/M: SY='K';  M= -4,  2,-22,  0,  3,-19,-16,  3,-20,  6,-18,-10,  4,-13,  3,  6, -1, -3,-16,-25, -7,  2;
/M: SY='E';  M= -9,  3,-28,  6, 17,-21, -1, -4,-26,  1,-20,-15,  3,-11,  3, -2, -1, -9,-23,-25,-15, 10;
/M: SY='N';  M= -9,  2,-27,  2,  0,-22,  3, -3,-22, -1,-18,-11,  4,-16, -4, -4, -4,-10,-19,-25,-14, -3;
/M: SY='T';  M= -4, -6,-20, -6, -1,-15,-20,-14, -7, -4, -9, -6, -7, -9, -6, -6, -2,  1, -2,-28,-12, -4;
/I:         I=-4; MI=0; IM=0; DM=-20; MD=-20;
/M: SY='V';  M= -5,-22,-16,-21,-22, -1,-28,-24, 19,-20,  7,  6,-22,-18,-23,-20,-12, -4, 26,-27, -8,-23;
/M: SY='D';  M=-15, 35,-27, 42, 10,-28, -7, -1,-29, -4,-24,-23, 21,-13, -3, -9,  1, -7,-25,-35,-16,  3;
/M: SY='I';  M= -4,-29,-21,-34,-28,  2,-33,-28, 34,-24, 13, 13,-24,-20,-24,-24,-15, -6, 33,-23, -5,-28;
/M: SY='F';  M=-13,-20,-15,-24,-16, 24,-26,-12, -6,-11,  1, -2,-16,-20,-18,-10,-14, -8, -6, -5, 16,-16;
/M: SY='Q';  M= -6,  3,-28,  4, 10,-29, -1,  1,-26,  4,-23,-12,  5,-12, 14,  1,  0, -9,-25,-23,-15, 12;
/M: SY='V';  M= -3,-17,-14,-24,-19,  1,-26,-16, 11,-19,  5,  4,-14,-20,-17,-18, -4,  9, 13,-23, -1,-19;
/M: SY='V';  M=  1,-26,-11,-29,-25, -1,-27,-25, 23,-21, 15, 13,-26,-26,-23,-20,-12, -2, 32,-27, -8,-25;
/M: SY='K';  M= -8, -5,-13, -7, -1,-18,-19, -9,-17, 11,-15, -6, -3,-17,  1,  9, -4, -3,-11,-25,-10,  0;
/M: SY='E';  M= -4, -3,-16, -6,  2,-15,-16,  0,-13, -3,-11, -2, -1,-15,  2, -3,  1, -2,-11,-27, -9,  2;
/M: SY='L';  M= -9,-27,-21,-32,-23,  6,-30,-18, 27,-24, 33, 29,-25,-25,-16,-20,-24, -9, 17,-20,  0,-20;
/M: SY='R';  M=-19, -7,-29, -8,  0,-21,-19, -1,-29, 29,-21,-10,  2,-19,  9, 62, -9, -9,-19,-21,-10,  0;
/M: SY='T';  M= -2, -2,-20, -5, -1,-17,-16, -8,-12,  0, -9, -4, -1,-15,  1, -1,  2,  3, -9,-27,-11,  0;
/M: SY='Q';  M= -8,  1,-27,  1, 15,-27,-18,  8,-19,  4,-17, -3,  1,-12, 35,  3,  0, -8,-24,-21, -6, 24;
/I:         I=-6; MI=-32; MD=-32; IM=-32;
/M: SY='R';  M=-19,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 68,-10,-10,-20,-20,-10,  0; D=-6;
/I:         I=-6; MI=-32; IM=-32; DM=-32;
/M: SY='P';  M= -7,-12,-17,-13, -9,-16,-14,-10,-11,-11,-15, -3, -8, 17, -9,-13, -6, -7,-14,-28,-17,-11;
/M: SY='G';  M= -5,-10,-22,-12,-14,-13, 19, -7,-22,-13,-16, -9, -3,-21,-10,-13, -4,-12,-19,-17, -9,-12;
/M: SY='M';  M= -5,-21,-15,-27,-20, -2,-18,-10, 14,-16, 18, 34,-20,-22, -9,-15,-16, -8, 10,-23, -5,-15;
/M: SY='V';  M= -4,-30,-15,-33,-30,  6,-32,-29, 33,-23, 12, 12,-27,-28,-28,-22,-13, -3, 42,-25, -5,-30;
/I:         I=-6; MI=0; IM=0; DM=-20; MD=-20;
/M: SY='Q';  M= -8,  4,-26,  6, 19,-35,-17,  4,-23,  7,-21, -7,  2,-10, 40,  7,  2, -6,-27,-24,-13, 29;
/M: SY='T';  M=  0,  4,-13, -4, -6,-14,-15,-13,-12, -9,-14,-10,  6,-12, -6, -9, 18, 33, -5,-32,-12, -6;
/M: SY='E';  M= -7,-12,-23,-11,  4, -5,-22,-14, -5, -8, -2, -4,-13,-11, -7,-11,-10, -8, -6,-19, -6, -2;
/M: SY='D';  M= -4, 15,-24, 22, 22,-29,-10, -6,-27, -1,-20,-18,  4, -6,  5, -8,  2, -6,-22,-31,-19, 13;
/M: SY='Q';  M=-10, -1,-30,  0, 20,-38,-20,  8,-20,  8,-19, -1, -1, -7, 54,  8, -1,-10,-29,-21,-11, 37;
/M: SY='Y';  M=-19,-22,-25,-23,-21, 33,-30, 11,  1,-14,  4,  1,-21,-30,-15,-12,-20,-10, -7, 22, 66,-21;
/M: SY='Q';  M= -6,-11,-25,-12, -1,-17,-21,-10, -3,  1, -7,  0, -9,-16,  4,  1, -6, -6, -2,-23, -8,  0;
/M: SY='F';  M=-16,-26,-17,-34,-26, 60,-28,-18, -1,-27,  8, -1,-18,-28,-33,-19,-15, -5, -1,  3, 25,-26;
/M: SY='I';  M= -4,-25,  1,-30,-24, -3,-29,-26, 19,-25, 13,  7,-21,-26,-21,-24,-13, -4, 18,-28, -9,-24;
/M: SY='Y';  M=-19,-14,-21,-15,-15, 13,-27, 37,-10,-11, -6, -1,-11,-28, -6, -8,-16,-13,-15,  7, 54,-15;
/M: SY='E';  M=-11,  5,-27,  9, 11,-24,-17,  2,-21,  6,-15, -8,  0,-13, 10,  6, -5, -8,-19,-25, -9,  9;
/M: SY='A';  M= 20,-18,  1,-25,-19,-12,-16,-24,  4,-17, -2, -1,-16,-19,-17,-21,  0,  0, 14,-26,-15,-19;
/M: SY='I';  M= -1,-27,-20,-31,-24,  0,-29,-23, 27,-23, 22, 17,-24,-24,-19,-21,-17, -6, 23,-22, -5,-23;
/M: SY='L';  M=  0,-20,-18,-23,-15, -1,-23,-17, 10,-20, 19,  9,-18,-22,-12,-17,-14, -7,  6,-21, -4,-14;
/M: SY='E';  M=-10,  6,-22,  9, 21,-21,-18,  3,-23,  2,-17,-13,  2,-11,  9,  0,  0, -5,-22,-27, -9, 15;
/M: SY='Y';  M= -6,-21,-24,-23,-17, 12,-19, -7, -1,-16,  2, -1,-19,-24,-15,-15,-14, -8, -3,  8, 23,-17;
/I:         E1=0; IE=-105; DE=-105;

» more

Post-processing [info]

COMPETES_HIT_WITH

PS50054; PS51181

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	233 in 186 different sequences
Number of true positive hits	233 in 186 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	25
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	90.31 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	2
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	K_Hofmann
Feature key [info]	DOMAIN
Feature description [info]	Tyrosine-protein phosphatase
Version [info]	6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

186 sequences

CSW_DROME   (P29349), CSW_DROVI   (Q24708), DEP1_CAEEL  (G5EGJ9),

EAK5_CAEEL  (G5EGA9), EAK6_CAEEL  (G5EGU2), EGG3_CAEEL  (Q20402), 
EGG4_CAEEL  (O01767), EGG5_CAEEL  (O61789), IDA1_CAEEL  (G5EGJ5), 
LAR_CAEEL   (Q9BMN8), LAR_DROME   (P16621), PTN11_CHICK (Q90687), 
PTN11_HUMAN (Q06124), PTN11_MOUSE (P35235), PTN11_RAT   (P41499), 
PTN12_HUMAN (Q05209), PTN12_MOUSE (P35831), PTN13_HUMAN (Q12923), 
PTN13_MOUSE (Q64512), PTN14_HUMAN (Q15678), PTN14_MOUSE (Q62130), 
PTN18_HUMAN (Q99952), PTN18_MOUSE (Q61152), PTN1_CHICK  (O13016), 
PTN1_HUMAN  (P18031), PTN1_MOUSE  (P35821), PTN1_RAT(P20417), 
PTN20_HUMAN (Q4JDL3), PTN20_MOUSE (O55082), PTN20_RAT   (A1L1L3), 
PTN21_HUMAN (Q16825), PTN21_MOUSE (Q62136), PTN21_RAT   (Q62728), 
PTN22_HUMAN (Q9Y2R2), PTN22_MOUSE (P29352), PTN23_HUMAN (Q9H3S7), 
PTN23_MOUSE (Q6PB44), PTN23_RAT   (O88902), PTN2_HUMAN  (P17706), 
PTN2_MOUSE  (Q06180), PTN2_RAT(P35233), PTN3_HUMAN  (P26045), 
PTN3_MOUSE  (A2ALK8), PTN4_HUMAN  (P29074), PTN4_MOUSE  (Q9WU22), 
PTN5_HUMAN  (P54829), PTN5_MOUSE  (P54830), PTN5_RAT(P35234), 
PTN6_HUMAN  (P29350), PTN6_MOUSE  (P29351), PTN6_RAT(P81718), 
PTN7_HUMAN  (P35236), PTN7_MOUSE  (Q8BUM3), PTN7_RAT(P49445), 
PTN9_HUMAN  (P43378), PTN9_MOUSE  (O35239), PTN9_RAT(Q641Z2), 
PTP10_DROME (P35992), PTP10_STYPL (P28202), PTP11_STYPL (P28203), 
PTP12_STYPL (P28204), PTP13_STYPL (P28205), PTP14_STYPL (P28206), 
PTP15_STYPL (P28207), PTP16_STYPL (P28208), PTP17_STYPL (P28209), 
PTP18_STYPL (P28210), PTP19_STYPL (P28211), PTP1_AEDAE  (A0A6I8TCE0), 
PTP1_ARATH  (O82656), PTP1_CAEEL  (P28191), PTP1_CULQU  (B0X4T2), 
PTP1_DICDI  (P34137), PTP1_STYPL  (P28193), PTP1_YEAST  (P25044), 
PTP20_STYPL (P28212), PTP21_STYPL (P28213), PTP22_STYPL (P28214), 
PTP23_STYPL (P28215), PTP24_STYPL (P28216), PTP25_STYPL (P28217), 
PTP26_STYPL (P28218), PTP27_STYPL (P28219), PTP2_CAEEL  (G5EC24), 
PTP2_DICDI  (P34138), PTP2_STYPL  (P28194), PTP2_YEAST  (P29461), 
PTP3_DICDI  (P54637), PTP3_STYPL  (P28195), PTP3_YEAST  (P40048), 
PTP4_CAEEL  (P28192), PTP4_STYPL  (P28196), PTP5_STYPL  (P28197), 
PTP61_DROME (Q9W0G1), PTP69_DROME (P16620), PTP6_STYPL  (P28198), 
PTP7_STYPL  (P28199), PTP8_STYPL  (P28200), PTP99_DROME (P35832), 
PTP9_STYPL  (P28201), PTPD1_MDBVW (Q5I154), PTPH1_MDBVW (Q5I147), 
PTPH2_MDBVW (Q5I146), PTPH3_MDBVW (Q5I145), PTPH4_MDBVW (Q5I143), 
PTPH5_MDBVW (Q5I142), PTPJ1_MDBVW (Q5I141), PTPJ2_MDBVW (Q5I139), 
PTPJ3_MDBVW (Q5I138), PTPJ4_MDBVW (Q5I137), PTPN1_MDBVW (Q5I128), 
PTPN2_MDBVW (Q5I127), PTPN3_MDBVW (Q5I124), PTPR2_HUMAN (Q92932), 
PTPR2_MACNE (O02695), PTPR2_MOUSE (P80560), PTPR2_RAT   (Q63475), 
PTPRA_HUMAN (P18433), PTPRA_MOUSE (P18052), PTPRA_RAT   (Q03348), 
PTPRB_HUMAN (P23467), PTPRB_MOUSE (B2RU80), PTPRC_CYPCA (Q9IBD8), 
PTPRC_HUMAN (P08575), PTPRC_MOUSE (P06800), PTPRC_RAT   (P04157), 
PTPRD_HUMAN (P23468), PTPRD_MOUSE (Q64487), PTPRE_HUMAN (P23469), 
PTPRE_MOUSE (P49446), PTPRE_RAT   (B2GV87), PTPRF_BOVIN (A7MBJ4), 
PTPRF_DANRE (A4IFW2), PTPRF_HUMAN (P10586), PTPRF_MOUSE (A2A8L5), 
PTPRF_RAT   (Q64604), PTPRG_CHICK (Q98936), PTPRG_HUMAN (P23470), 
PTPRG_MOUSE (Q05909), PTPRH_HUMAN (Q9HD43), PTPRH_MOUSE (E9Q0N2), 
PTPRJ_CHICK (Q9W6V5), PTPRJ_HUMAN (Q12913), PTPRJ_MOUSE (Q64455), 
PTPRK_HUMAN (Q15262), PTPRK_MOUSE (P35822), PTPRM_HUMAN (P28827), 
PTPRM_MOUSE (P28828), PTPRN_BOVIN (P56722), PTPRN_HUMAN (Q16849), 
PTPRN_MOUSE (Q60673), PTPRN_RAT   (Q63259), PTPRO_HUMAN (Q16827), 
PTPRO_MOUSE (E9Q612), PTPRQ_HUMAN (Q9UMZ3), PTPRQ_MOUSE (P0C5E4), 
PTPRQ_RAT   (O88488), PTPRR_HUMAN (Q15256), PTPRR_MOUSE (Q62132), 
PTPRR_RAT   (O08617), PTPRS_CHICK (F1NWE3), PTPRS_HUMAN (Q13332), 
PTPRS_MOUSE (B0V2N1), PTPRS_RAT   (Q64605), PTPRT_HUMAN (O14522), 
PTPRT_MOUSE (Q99M80), PTPRU_CHICK (Q6YI48), PTPRU_DANRE (B3DK56), 
PTPRU_HUMAN (Q92729), PTPRU_MOUSE (B1AUH1), PTPRV_MOUSE (P70289), 
PTPRV_RAT   (Q64612), PTPRZ_HUMAN (P23471), PTPRZ_MOUSE (B9EKR1), 
PTPRZ_RAT   (Q62656), PTPR_CAEEL  (H2KZM6), PYP1_SCHPO  (P27574), 
PYP2_SCHPO  (P32586), PYP3_SCHPO  (P32587), SPTP_SALPA  (Q5PEA9), 
SPTP_SALTI  (P74851), SPTP_SALTY  (P74873), YK13_CAEEL  (P34337), 
YKCA_CAEEL  (P42083), YOPH_YEREN  (P15273), YOPH_YERPS  (P08538)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

25 sequences

CDC14_CAEEL (P81299), HOPD2_PSESM (Q79LY0), PRL1_DROME  (O61722),

PRL1_LEIMA  (Q4QEZ7), PRL1_TRYCC  (Q4CUJ8), PTPC1_BOVIN (A7E379), 
PTPC1_DANRE (A1L1R5), PTPC1_HUMAN (A2A3K4), PTPC1_MOUSE (Q6NZK8), 
TP4A1_HUMAN (Q93096), TP4A1_MACFA (Q9TSM6), TP4A1_MOUSE (Q63739), 
TP4A1_PONAB (Q5R7J8), TP4A1_RAT   (Q78EG7), TP4A2_HUMAN (Q12974), 
TP4A2_MOUSE (O70274), TP4A2_RAT   (Q6P9X4), TP4A3_BOVIN (A2VDT1), 
TP4A3_HUMAN (O75365), TP4A3_MOUSE (Q9D658), TP4AA_DICDI (Q54DU9), 
TP4AB_DICDI (Q86IL4), VF197_IIV3  (Q196Z3), VF197_IIV6  (Q91FX3), 
VHP1_CAEEL  (Q10038)

» more

PDB
[Detailed view]

713 PDB

pdb_00001a5y; pdb_00001aax; pdb_00001bzc; pdb_00001bzh; pdb_00001bzj; pdb_00001c83; pdb_00001c84; pdb_00001c85; pdb_00001c86; pdb_00001c87; pdb_00001c88; pdb_00001ecv; pdb_00001een; pdb_00001eeo; pdb_00001fpr; pdb_00001g1f; pdb_00001g1g; pdb_00001g1h; pdb_00001g4u; pdb_00001g4w; pdb_00001g7f; pdb_00001g7g; pdb_00001gfy; pdb_00001gwz; pdb_00001i57; pdb_00001jf7; pdb_00001jln; pdb_00001kak; pdb_00001kav; pdb_00001l8g; pdb_00001l8k; pdb_00001lar; pdb_00001lqf; pdb_00001lyv; pdb_00001nl9; pdb_00001nny; pdb_00001no6; pdb_00001nwe; pdb_00001nwl; pdb_00001nz7; pdb_00001oem; pdb_00001oeo; pdb_00001oes; pdb_00001oet; pdb_00001oeu; pdb_00001oev; pdb_00001ony; pdb_00001onz; pdb_00001p15; pdb_00001pa1; pdb_00001pa9; pdb_00001ph0; pdb_00001ptt; pdb_00001ptu; pdb_00001ptv; pdb_00001pty; pdb_00001pxh; pdb_00001pyn; pdb_00001q1m; pdb_00001q6j; pdb_00001q6m; pdb_00001q6n; pdb_00001q6p; pdb_00001q6s; pdb_00001q6t; pdb_00001qxk; pdb_00001r6h; pdb_00001rpm; pdb_00001rxd; pdb_00001sug; pdb_00001t48; pdb_00001t49; pdb_00001t4j; pdb_00001v3a; pdb_00001wax; pdb_00001wch; pdb_00001x24; pdb_00001xbo; pdb_00001xxp; pdb_00001xxv; pdb_00001yfo; pdb_00001ygr; pdb_00001ygu; pdb_00001ypt; pdb_00001ytn; pdb_00001yts; pdb_00001ytw; pdb_00001zc0; pdb_00001zck; pdb_00002a3k; pdb_00002a8b; pdb_00002ahs; pdb_00002azr; pdb_00002b07; pdb_00002b3o; pdb_00002b49; pdb_00002b4s; pdb_00002bgd; pdb_00002bge; pdb_00002bij; pdb_00002bv5; pdb_00002bzl; pdb_00002c7s; pdb_00002cfv; pdb_00002cjz; pdb_00002cm2; pdb_00002cm3; pdb_00002cm7; pdb_00002cm8; pdb_00002cma; pdb_00002cmb; pdb_00002cmc; pdb_00002cne; pdb_00002cnf; pdb_00002cng; pdb_00002cnh; pdb_00002cni; pdb_00002f6f; pdb_00002f6t; pdb_00002f6v; pdb_00002f6w; pdb_00002f6y; pdb_00002f6z; pdb_00002f70; pdb_00002f71; pdb_00002fh7; pdb_00002fjm; pdb_00002fjn; pdb_00002g59; pdb_00002gjt; pdb_00002gp0; pdb_00002h02; pdb_00002h03; pdb_00002h04; pdb_00002h4g; pdb_00002h4k; pdb_00002h4v; pdb_00002hb1; pdb_00002hc1; pdb_00002hc2; pdb_00002hnp; pdb_00002hnq; pdb_00002hvl; pdb_00002hy3; pdb_00002i1y; pdb_00002i3r; pdb_00002i3u; pdb_00002i42; pdb_00002i4e; pdb_00002i4g; pdb_00002i4h; pdb_00002i5x; pdb_00002i75; pdb_00002jjd; pdb_00002mbc; pdb_00002nlk; pdb_00002nt7; pdb_00002nta; pdb_00002nv5; pdb_00002nz6; pdb_00002oc3; pdb_00002ooq; pdb_00002p6x; pdb_00002pa5; pdb_00002pbn; pdb_00002qbp; pdb_00002qbq; pdb_00002qbr; pdb_00002qbs; pdb_00002qcj; pdb_00002qct; pdb_00002qdc; pdb_00002qdm; pdb_00002qdp; pdb_00002qep; pdb_00002shp; pdb_00002veu; pdb_00002vev; pdb_00002vew; pdb_00002vex; pdb_00002vey; pdb_00002zmm; pdb_00002zn7; pdb_00003a5j; pdb_00003a5k; pdb_00003b7o; pdb_00003blt; pdb_00003blu; pdb_00003bm8; pdb_00003brh; pdb_00003cwe; pdb_00003d42; pdb_00003d44; pdb_00003d9c; pdb_00003eax; pdb_00003eb1; pdb_00003eu0; pdb_00003f99; pdb_00003f9a; pdb_00003f9b; pdb_00003h2x; pdb_00003i7z; pdb_00003i80; pdb_00003mow; pdb_00003o4s; pdb_00003o4t; pdb_00003o4u; pdb_00003o5x; pdb_00003olr; pdb_00003omh; pdb_00003ps5; pdb_00003qcb; pdb_00003qcc; pdb_00003qcd; pdb_00003qce; pdb_00003qcf; pdb_00003qcg; pdb_00003qch; pdb_00003qci; pdb_00003qcj; pdb_00003qck; pdb_00003qcl; pdb_00003qcm; pdb_00003qcn; pdb_00003qkp; pdb_00003qkq; pdb_00003rz2; pdb_00003s3e; pdb_00003s3f; pdb_00003s3h; pdb_00003s3k; pdb_00003s4o; pdb_00003sme; pdb_00003sr9; pdb_00003u96; pdb_00003zm0; pdb_00003zm1; pdb_00003zm2; pdb_00003zm3; pdb_00003zmp; pdb_00003zmq; pdb_00003zv2; pdb_00004bjo; pdb_00004bpc; pdb_00004dgp; pdb_00004dgx; pdb_00004ge2; pdb_00004ge5; pdb_00004ge6; pdb_00004gfu; pdb_00004gfv; pdb_00004gry; pdb_00004grz; pdb_00004gs0; pdb_00004gwf; pdb_00004h1o; pdb_00004h34; pdb_00004hjp; pdb_00004hjq; pdb_00004i8n; pdb_00004icz; pdb_00004ikc; pdb_00004j51; pdb_00004nnd; pdb_00004nwf; pdb_00004nwg; pdb_00004ohd; pdb_00004ohe; pdb_00004ohh; pdb_00004ohi; pdb_00004ohl; pdb_00004pvg; pdb_00004qah; pdb_00004qap; pdb_00004qbe; pdb_00004qbw; pdb_00004qum; pdb_00004qun; pdb_00004rdd; pdb_00004rh5; pdb_00004rh9; pdb_00004rhg; pdb_00004ri4; pdb_00004ri5; pdb_00004s0g; pdb_00004y14; pdb_00004yaa; pdb_00004z6b; pdb_00004zi4; pdb_00004zn5; pdb_00004zrt; pdb_00005awx; pdb_00005bk8; pdb_00005bx1; pdb_00005ehp; pdb_00005ehr; pdb_00005h08; pdb_00005hde; pdb_00005i6v; pdb_00005ibm; pdb_00005ibs; pdb_00005j8r; pdb_00005k22; pdb_00005k23; pdb_00005k24; pdb_00005k25; pdb_00005k9v; pdb_00005k9w; pdb_00005ka0; pdb_00005ka1; pdb_00005ka2; pdb_00005ka3; pdb_00005ka4; pdb_00005ka7; pdb_00005ka8; pdb_00005ka9; pdb_00005kaa; pdb_00005kab; pdb_00005kac; pdb_00005kad; pdb_00005lxq; pdb_00005mmz; pdb_00005ovr; pdb_00005ovx; pdb_00005ow1; pdb_00005qde; pdb_00005qdf; pdb_00005qdg; pdb_00005qdh; pdb_00005qdi; pdb_00005qdj; pdb_00005qdk; pdb_00005qdl; pdb_00005qdm; pdb_00005qdn; pdb_00005qdo; pdb_00005qdp; pdb_00005qdq; pdb_00005qdr; pdb_00005qds; pdb_00005qdt; pdb_00005qdu; pdb_00005qdv; pdb_00005qdw; pdb_00005qdx; pdb_00005qdy; pdb_00005qdz; pdb_00005qe0; pdb_00005qe1; pdb_00005qe2; pdb_00005qe3; pdb_00005qe4; pdb_00005qe5; pdb_00005qe6; pdb_00005qe7; pdb_00005qe8; pdb_00005qe9; pdb_00005qea; pdb_00005qeb; pdb_00005qec; pdb_00005qed; pdb_00005qee; pdb_00005qef; pdb_00005qeg; pdb_00005qeh; pdb_00005qei; pdb_00005qej; pdb_00005qek; pdb_00005qel; pdb_00005qem; pdb_00005qen; pdb_00005qeo; pdb_00005qep; pdb_00005qeq; pdb_00005qer; pdb_00005qes; pdb_00005qet; pdb_00005qeu; pdb_00005qev; pdb_00005qew; pdb_00005qex; pdb_00005qey; pdb_00005qez; pdb_00005qf0; pdb_00005qf1; pdb_00005qf2; pdb_00005qf3; pdb_00005qf4; pdb_00005qf5; pdb_00005qf6; pdb_00005qf7; pdb_00005qf8; pdb_00005qf9; pdb_00005qfa; pdb_00005qfb; pdb_00005qfc; pdb_00005qfd; pdb_00005qfe; pdb_00005qff; pdb_00005qfg; pdb_00005qfh; pdb_00005qfi; pdb_00005qfj; pdb_00005qfk; pdb_00005qfl; pdb_00005qfm; pdb_00005qfn; pdb_00005qfo; pdb_00005qfp; pdb_00005qfq; pdb_00005qfr; pdb_00005qfs; pdb_00005qft; pdb_00005qfu; pdb_00005qfv; pdb_00005qfw; pdb_00005qfx; pdb_00005qfy; pdb_00005qfz; pdb_00005qg0; pdb_00005qg1; pdb_00005qg2; pdb_00005qg3; pdb_00005qg4; pdb_00005qg5; pdb_00005qg6; pdb_00005qg7; pdb_00005qg8; pdb_00005qg9; pdb_00005qga; pdb_00005qgb; pdb_00005qgc; pdb_00005qgd; pdb_00005qge; pdb_00005qgf; pdb_00005t19; pdb_00005xzr; pdb_00006atd; pdb_00006b8e; pdb_00006b8t; pdb_00006b8x; pdb_00006b8z; pdb_00006b90; pdb_00006b95; pdb_00006bai; pdb_00006bmr; pdb_00006bmu; pdb_00006bmv; pdb_00006bmw; pdb_00006bmx; pdb_00006bmy; pdb_00006bn5; pdb_00006cmp; pdb_00006cmq; pdb_00006cmr; pdb_00006cms; pdb_00006crf; pdb_00006crg; pdb_00006cwu; pdb_00006cwv; pdb_00006d3f; pdb_00006d4d; pdb_00006d4f; pdb_00006h8r; pdb_00006h8s; pdb_00006iwd; pdb_00006j6u; pdb_00006kip; pdb_00006kr4; pdb_00006krw; pdb_00006krx; pdb_00006kzq; pdb_00006l03; pdb_00006md7; pdb_00006md9; pdb_00006mda; pdb_00006mdb; pdb_00006mdc; pdb_00006mdd; pdb_00006ntp; pdb_00006ol4; pdb_00006olq; pdb_00006olv; pdb_00006omy; pdb_00006pfw; pdb_00006pg0; pdb_00006pgt; pdb_00006pha; pdb_00006phs; pdb_00006pm8; pdb_00006sub; pdb_00006suc; pdb_00006t36; pdb_00006uzt; pdb_00006w30; pdb_00006wu8; pdb_00006xe8; pdb_00006xea; pdb_00006xed; pdb_00006xee; pdb_00006xef; pdb_00006xeg; pdb_00006xft; pdb_00006zz4; pdb_00007emn; pdb_00007f5n; pdb_00007f5o; pdb_00007fqm; pdb_00007fqn; pdb_00007fqo; pdb_00007fqp; pdb_00007fqq; pdb_00007fqr; pdb_00007fqs; pdb_00007fqt; pdb_00007fqu; pdb_00007fqv; pdb_00007fqw; pdb_00007fqx; pdb_00007fqy; pdb_00007fqz; pdb_00007fre; pdb_00007frf; pdb_00007frg; pdb_00007frh; pdb_00007fri; pdb_00007frj; pdb_00007frk; pdb_00007frl; pdb_00007frm; pdb_00007frn; pdb_00007fro; pdb_00007frp; pdb_00007frq; pdb_00007frr; pdb_00007frs; pdb_00007frt; pdb_00007fru; pdb_00007gs7; pdb_00007gs8; pdb_00007gs9; pdb_00007gsa; pdb_00007gsb; pdb_00007gsc; pdb_00007gsd; pdb_00007gse; pdb_00007gsf; pdb_00007gsg; pdb_00007gsh; pdb_00007gsi; pdb_00007gsj; pdb_00007gsk; pdb_00007gsl; pdb_00007gsm; pdb_00007gsn; pdb_00007gso; pdb_00007gsq; pdb_00007gsr; pdb_00007gst; pdb_00007gsu; pdb_00007gsv; pdb_00007gsw; pdb_00007gsx; pdb_00007gsy; pdb_00007gsz; pdb_00007gt0; pdb_00007gt1; pdb_00007gt2; pdb_00007gt3; pdb_00007gt4; pdb_00007gt5; pdb_00007gt6; pdb_00007gt7; pdb_00007gt8; pdb_00007gt9; pdb_00007gta; pdb_00007gtb; pdb_00007gtc; pdb_00007gtd; pdb_00007gte; pdb_00007gtf; pdb_00007gtg; pdb_00007gth; pdb_00007gti; pdb_00007gtj; pdb_00007gtk; pdb_00007gtl; pdb_00007gtm; pdb_00007gtn; pdb_00007gto; pdb_00007gtp; pdb_00007gtq; pdb_00007gtr; pdb_00007gts; pdb_00007gtt; pdb_00007gtu; pdb_00007gtv; pdb_00007gtw; pdb_00007gtx; pdb_00007gty; pdb_00007gtz; pdb_00007gu0; pdb_00007gu1; pdb_00007gu2; pdb_00007gu3; pdb_00007gu4; pdb_00007gu5; pdb_00007gu6; pdb_00007gu7; pdb_00007gu8; pdb_00007gu9; pdb_00007gua; pdb_00007gub; pdb_00007guc; pdb_00007jvm; pdb_00007jvn; pdb_00007ken; pdb_00007key; pdb_00007klx; pdb_00007l0c; pdb_00007l0h; pdb_00007lfo; pdb_00007mkz; pdb_00007mm1; pdb_00007mn7; pdb_00007mn9; pdb_00007mna; pdb_00007mnb; pdb_00007mnc; pdb_00007mnd; pdb_00007mne; pdb_00007mnf; pdb_00007mou; pdb_00007mov; pdb_00007mow; pdb_00007r75; pdb_00007r7d; pdb_00007r7i; pdb_00007r7l; pdb_00007rct; pdb_00007rin; pdb_00007s4f; pdb_00007tvj; pdb_00007uad; pdb_00007vxg; pdb_00007xc0; pdb_00007xhq; pdb_00008b5y; pdb_00008cbh; pdb_00008du7; pdb_00008exi; pdb_00008exj; pdb_00008exk; pdb_00008exm; pdb_00008exn; pdb_00008eya; pdb_00008eyb; pdb_00008eyc; pdb_00008f88; pdb_00008g65; pdb_00008g67; pdb_00008g68; pdb_00008g69; pdb_00008g6a; pdb_00008gvv; pdb_00008gwh; pdb_00008gww; pdb_00008gxe; pdb_00008jbn; pdb_00008jby; pdb_00008rzw; pdb_00008rzy; pdb_00008s01; pdb_00008s04; pdb_00008s06; pdb_00008s07; pdb_00008s0h; pdb_00008s0i; pdb_00008s0j; pdb_00008s0k; pdb_00008s0o; pdb_00008s0p; pdb_00008s0q; pdb_00008s0s; pdb_00008skl; pdb_00008sls; pdb_00008slt; pdb_00008slu; pdb_00008t6d; pdb_00008t6g; pdb_00008t7q; pdb_00008t8q; pdb_00008u0h; pdb_00008u1e; pdb_00008u7w; pdb_00008u7x; pdb_00008uh6; pdb_00008wfy; pdb_00008wx7; pdb_00008xoy; pdb_00008xqd; pdb_00008yhi; pdb_00009blg; pdb_00009c54; pdb_00009c55; pdb_00009c56; pdb_00009cyo; pdb_00009cyp; pdb_00009cyq; pdb_00009cyr; pdb_00009eex; pdb_00009eey; pdb_00009eez
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