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Entry: PS50056

General information about the entry

Entry name [info] TYR_PHOSPHATASE_2
Accession [info] PS50056
Entry type [info] MATRIX
Date [info] NOV-1997 (CREATED); OCT-2013 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC00323

Name and characterization of the entry

Description [info] Tyrosine specific protein phosphatases family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=68;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=63;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.7969000; R2=0.0165700; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2939.9223633; R2=3.8252428; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=465; H_SCORE=4719; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=345; H_SCORE=4260; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105; MM=1; M0=-1;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='E'; M= -9, -3,-21,  0,  5,-18,-20, -6,-15,  1, -6, -7, -6,-13,  1,  2, -8, -7,-13,-25,-10,  2;
/M: SY='D'; M= -9, 10,-25, 13, 10,-22,-12,  0,-24,  5,-20,-15,  8,-12,  3,  2,  2, -4,-20,-28,-11,  6;
/M: SY='F'; M=-14,-27,-24,-34,-26, 39,-27,-18,  6,-25,  9,  2,-21,-25,-28,-20,-19,-10,  2, 10, 19,-25;
/M: SY='L'; M= -6,-22,-21,-24,-16,  2,-26,-18, 13,-19, 14,  8,-19,-20,-15,-16,-14, -6, 11,-20, -3,-16;
/M: SY='E'; M= -7,  5,-26,  7, 10,-24,-10, -2,-24,  7,-22,-13,  5, -8,  8,  6,  1, -5,-21,-27,-14,  8;
/M: SY='M'; M= -4,-13,-21,-15, -5, -2,-19,-12, -4, -7,  1,  3,-12,-17, -6, -6, -9, -6, -3,-19, -4, -5;
/M: SY='V'; M=  1,-24,-12,-27,-23, -2,-27,-24, 19,-19, 11,  8,-22,-24,-21,-19,-10, -1, 24,-25, -7,-22;
/M: SY='R'; M=-10,  5,-25,  4,  7,-23,-17,  2,-22, 13,-20, -9,  6,-14,  9, 14, -2, -6,-19,-26,-10,  7;
/M: SY='E'; M= -4,  1,-22, -2,  3,-12,-17, -3,-14, -2,-13, -7,  2,-13,  2, -4,  2,  3,-12,-23, -6,  2;
/I:         MD=-15;
/M: SY='I'; M= -6,-19,-13,-23,-17,  4,-24,-14,  7,-15,  5,  4,-16,-21,-15,-13,-10, -4,  7,-16,  1,-16; D=-2;
/I:         MD=-15;
/M: SY='Y'; M=-10, -7,-22, -9, -6, -4,-19, -5, -5, -5, -3, -2, -5,-17, -5, -2, -8, -4, -5,-18,  1, -7; D=-2;
/I:         MD=-15;
/M: SY='E'; M= -6,  3,-19,  4,  9,-22,-12, -5,-20,  6,-19,-12,  2, -1,  5,  4,  0, -4,-18,-24,-15,  6; D=-2;
/I:         MD=-15;
/M: SY='E'; M= -3, -3,-19, -3,  5,-16,-14, -3,-13,  4,-12, -6, -4, -7,  4,  0, -2, -5,-10,-19, -9,  4; D=-2;
/I:         I=-4; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='K'; M= -3, -2,-14, -2,  2,-11, -6, -4,-12,  3, -9, -5, -2, -5,  1,  2, -1, -2, -9,-13, -7,  1; D=-2;
/I:         DM=-15;
/M: SY='S'; M= -4,  2,-19,  1,  3,-21, -9, -1,-21, -1,-19,-11,  3,-12,  4, -2,  5, -1,-17,-28,-11,  3;
/M: SY='E'; M= -4, -1,-25,  0,  5,-24,-14, -3,-20,  5,-21,-12,  1,  4,  4,  2,  0, -4,-19,-27,-15,  3;
/M: SY='G'; M= -3,  0,-27,  0,-10,-27, 40,-11,-34,-13,-28,-19,  7,-18,-11,-13,  4,-12,-27,-24,-23,-11;
/M: SY='P'; M= -5,-10,-14,-10, -5,-24,  0,-13,-24, -4,-22,-14, -6,  4, -7, -5, -3, -8,-19,-28,-21, -8;
/I:         MD=-21;
/M: SY='P'; M= -6, -7,-17, -6,  0,-17,-10, -9,-14,  2,-14, -8, -6,  8, -2,  1, -5, -6,-13,-20,-13, -3; D=-4;
/I:         I=-5; MI=0; IM=0; DM=-21;
/M: SY='I'; M= -4,-27,-18,-32,-26, -1,-32,-27, 30,-24, 15, 13,-22,-21,-22,-23,-14, -3, 28,-24, -5,-26;
/M: SY='V'; M= -2,-25,-13,-28,-23,  0,-24,-22, 18,-23, 17,  9,-23,-26,-22,-21,-14, -3, 21,-24, -6,-23;
/M: SY='V'; M= -1,-29,-14,-31,-29,  1,-31,-29, 32,-22, 12, 11,-28,-28,-28,-22,-11, -1, 44,-28, -8,-29;
/M: SY='H'; M=-19, -1,-29, -1, -1,-19,-20, 94,-28,-10,-20,  0,  9,-20,  9, -1, -9,-18,-28,-29, 19, -1;
/M: SY='C'; M=-10,-20,117,-30,-30,-20,-28,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-49,-30,-30;
/M: SY='S'; M=  3, -6,-15, -8, -4,-15, -9,-11,-12, -7,-15, -9,  0,-15, -1, -4, 16,  8, -6,-31,-13, -3;
/M: SY='A'; M= 30, -4,-11,-11, -8,-20, -1,-13,-13,-10,-12, -9, -4,-13, -9,-17,  6, -2, -5,-24,-18, -9;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='V'; M= -3,-24,-14,-28,-22, -4,-27,-21, 19,-20, 10,  8,-20,-24,-18,-18,-12, -4, 21,-25, -6,-22;
/M: SY='G'; M=  1, -4,-25, -5,-13,-27, 46,-15,-34,-15,-29,-19,  6,-17,-12,-15,  9,-10,-25,-25,-26,-13;
/M: SY='R'; M=-18,-10,-29,-10,  1,-20,-20, -1,-28, 28,-19,-10,  0,-19, 10, 64, -9, -9,-19,-20,-10,  1;
/M: SY='T'; M=  6, -1, -8, -7, -6,-15,-11,-16,-14,-10,-18,-14,  3,-10, -6,-11, 27, 35, -4,-34,-15, -6;
/M: SY='G'; M=  8,-11,-23,-12,-16,-26, 42,-20,-30,-16,-25,-17, -4,-12,-17,-19,  3,-12,-20,-22,-26,-17;
/M: SY='T'; M=  0,-11, -3,-18,-16, -7,-22,-20,  0,-15, -3, -3,-10,-18,-14,-15,  6, 22,  8,-28, -8,-16;
/M: SY='F'; M=-12,-29,-20,-34,-26, 35,-30,-19, 15,-26, 20, 11,-24,-28,-28,-20,-20, -8, 13, -7, 15,-26;
/M: SY='I'; M= -2,-24,  0,-31,-26, -5,-30,-27, 22,-24,  8,  7,-20,-24,-21,-24,-11, -3, 22,-27, -9,-26;
/M: SY='A'; M= 16,-18, -8,-24,-19,-10,-12,-22,  4,-18,  3,  1,-16,-20,-17,-20, -3, -1, 11,-24,-14,-18;
/M: SY='I'; M=  8,-21,-12,-27,-19, -5,-22,-21, 13,-19, 11,  8,-18,-21,-16,-19, -9, -4, 12,-23, -9,-19;
/M: SY='Y'; M=-12,  1,-25,  5,  0, -4,-18,  3,-17, -8,-11,-10, -5,-19, -6,-10, -8, -9,-16, -4, 14, -4;
/M: SY='L'; M= -6,-20,-17,-25,-19,  1,-27,-17, 15,-21, 17, 11,-17,-23,-16,-17,-14, -4, 10,-20,  0,-19;
/M: SY='M'; M= -6,-23,-15,-29,-22, -1,-22,-16, 19,-20, 18, 27,-20,-23,-14,-18,-17, -7, 14,-23, -5,-19;
/I:         I=-5; MI=0; IM=0; DM=-15; MD=-15;
/M: SY='E'; M= -6,  4,-25,  4, 14,-21,-12, -4,-20,  2,-18,-13,  3, -8,  4, -2,  1, -2,-19,-25,-11,  8;
/M: SY='E'; M= -8, -3,-20, -3,  1,-15,-10, -4,-18, -2,-11, -7, -3,-15, -1, -2, -6, -8,-16,-23, -8, -1;
/M:         M= -6, -3,-18, -5, -5,-19, -3,-10,-15, -6,-16, -9,  0,-14, -5, -6, -1, -4,-10,-27,-15, -6;
/M: SY='I'; M= -8,-26,-16,-29,-22,  6,-29,-21, 19,-20, 16, 14,-23,-25,-20,-17,-17, -7, 19,-17, -1,-21;
/M: SY='D'; M= -9, 20,-24, 25,  8,-27, -8, -4,-27,  2,-26,-20, 13,-10,  1, -2,  8,  1,-21,-33,-15,  4;
/M: SY='I'; M= -3,-24,-22,-26,-19, -1,-27,-21, 16,-20,  9,  6,-21,-11,-18,-20,-12, -5, 15,-19, -2,-20;
/M:         M= -9, -4,-23, -6, -1,  0,-16, -6,-15, -5,-10, -9, -3,-13, -7, -4, -7, -8,-15,-17, -1, -4;
/M: SY='D'; M= -9, 14,-27, 20, 16,-29, -8,  1,-28,  3,-23,-16,  8, -9, 10, -1,  1, -8,-25,-29,-16, 13;
/M: SY='A'; M= 17,-16, -9,-23,-17, -7,-16,-20,  3,-16,  1,  0,-14,-17,-15,-19,  0,  4,  9,-23,-11,-16;
/M: SY='V'; M= -7,-27,-19,-31,-26,  8,-31,-21, 24,-21, 15, 12,-24,-27,-22,-18,-16, -5, 26,-15,  6,-26;
/M: SY='K'; M= -9,  2,-21,  5,  8,-23,-16, -3,-22,  9,-16,-11, -1,-14,  6,  8, -3, -7,-18,-26,-11,  6;
/M: SY='Y'; M= -7,-11,-22,-14, -5, -1,-20, -6, -7, -6, -3,  0, -8,-18, -4, -4, -7, -4, -7,-15,  3, -5;
/M: SY='L'; M= -8,-28,-19,-31,-23,  7,-29,-20, 24,-24, 29, 23,-26,-27,-18,-19,-21, -8, 20,-21, -1,-21;
/M: SY='R'; M=-17, -7,-29, -7,  4,-22,-20,  0,-28, 29,-21, -9,  0,-17, 12, 53, -9,-10,-20,-20, -9,  4;
/M: SY='Q'; M= -5,  1,-23,  1,  5,-21,-16, -1,-17,  4,-15, -7,  1,-14,  8,  3,  1, -1,-14,-26,-10,  6;
/M: SY='Q'; M= -7, -5,-22, -6,  3,-21,-19,  2,-18,  8,-15, -4, -3,-16, 17, 11, -4, -8,-17,-20, -5,  9;
/M: SY='R'; M=-19, -8,-30, -8,  1,-21,-20, -1,-30, 31,-21,-10,  1,-19, 10, 65,-10,-10,-20,-20,-10,  1;
/M: SY='P'; M= -7,-12,-27,-11, -6,-20,-12, -9,-15, -8,-17, -8, -7, 26, -7, -8, -6, -7,-18,-28,-19, -9;
/M: SY='G'; M= -3, -4,-25, -8,-13,-18, 27, -6,-23,-14,-19, -9,  5,-20,-10,-13,  0,-11,-21,-22,-15,-12;
/M: SY='M'; M=  0,-19,-19,-25,-17, -4,-16,-11, 11,-14, 14, 27,-17,-20, -8,-13,-11, -6,  7,-22, -6,-13;
/M: SY='V'; M= -2,-28,-16,-31,-28,  2,-28,-28, 28,-22, 10, 11,-24,-26,-26,-22,-11, -3, 36,-25, -7,-28;
/M: SY='Q'; M= -9, -2,-25, -5,  9,-28,-19,  1,-11,  1,-12, -1,  0,-14, 32,  2, -2, -7,-18,-24,-11, 20;
/M: SY='T'; M=  0,  0,-14, -5, -4,-17,-13,-12,-14, -7,-15, -9,  1,-11,  0, -7, 17, 29, -7,-30,-12, -2;
/M: SY='E'; M=-10,  0,-26,  4, 11,-16,-19, -9,-20,  1,-16,-13, -4,  6,  0, -5, -5, -6,-20,-24,-11,  5;
/M: SY='E'; M= -3, 10,-23, 13, 23,-27,-13, -1,-23,  1,-19,-14,  4, -9, 11, -5,  3, -5,-21,-30,-16, 17;
/M: SY='Q'; M=-11, -2,-29, -2, 16,-34,-21, 11,-18,  8,-15,  1, -2,-12, 47,  8, -4,-11,-26,-21, -8, 31;
/M: SY='Y'; M=-17,-14,-29,-13,-12, 14,-27, 11, -6, -5, -2, -2,-15,-23, -5, -5,-16, -9,-12, 11, 48,-12;
/M: SY='Y'; M= -9,-15,-25,-17, -6, -2,-25, -7,  0, -6, -1,  0,-13,-20, -4, -3,-11, -6, -1,-12,  6, -7;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 405 in 365 different sequences
Number of true positive hits 403 in 363 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 42
Number of 'partial' sequences 27
Precision (true positives / (true positives + false positives)) 99.51 %
Recall (true positives / (true positives + false negatives)) 90.56 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 2
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
363 sequences

123R_IIV6   (O55737    ), CC14A_HUMAN (Q9UNH5    ), CC14A_MOUSE (Q6GQT0    ), 
CC14B_HUMAN (O60729    ), CC14B_MOUSE (Q6PFY9    ), CC14C_HUMAN (A4D256    ), 
CC14C_SYMSY (A6N3Q4    ), CDC14_CAEEL (P81299    ), CDC14_CANAL (Q59NH8    ), 
CDC14_EMENI (Q5B323    ), CDC14_YEAST (Q00684    ), CDKN3_HUMAN (Q16667    ), 
CDKN3_MOUSE (Q810P3    ), CDKN3_PIG   (Q9MYN5    ), CDKN3_RAT   (B2RZ50    ), 
CPP1_CANAL  (Q5APU2    ), CSW_DROME   (P29349    ), CSW_DROSI   (Q8ISC9    ), 
CSW_DROVI   (Q24708    ), DEP1_CAEEL  (G5EGJ9    ), DPHS1_ARATH (Q75QN6    ), 
DS13A_HUMAN (Q6B8I1    ), DS13A_MOUSE (Q6B8I0    ), DS13B_HUMAN (Q9UII6    ), 
DS13B_MOUSE (Q9QYJ7    ), DS22A_DANRE (Q1LWL2    ), DS22B_DANRE (Q566R7    ), 
DSP4_ARATH  (Q9FEB5    ), DSP4_CASSA  (G4LTX4    ), DSP8_ARATH  (Q9ZQP1    ), 
DUPD1_ANOCA (P0C598    ), DUPD1_BOVIN (P0C591    ), DUPD1_CALMI (P0C5A2    ), 
DUPD1_CHICK (P0C597    ), DUPD1_DANRE (Q29RA3    ), DUPD1_GASAC (P0C5A0    ), 
DUPD1_HORSE (P0C592    ), DUPD1_HUMAN (Q68J44    ), DUPD1_MONDO (P0C593    ), 
DUPD1_MOUSE (Q8BK84    ), DUPD1_ORYLA (P0C5A1    ), DUPD1_PANTR (P0C594    ), 
DUPD1_PIG   (P0C596    ), DUPD1_RAT   (P0C595    ), DUPD1_TAKRU (P0C599    ), 
DUPD1_TETNG (Q4RQD3    ), DUPD1_XENLA (Q4KL92    ), DUPD1_XENTR (A4IHU7    ), 
DUS10_BOVIN (Q0IID7    ), DUS10_HUMAN (Q9Y6W6    ), DUS10_MOUSE (Q9ESS0    ), 
DUS11_BOVIN (Q5E999    ), DUS11_HUMAN (O75319    ), DUS11_MOUSE (Q6NXK5    ), 
DUS11_RAT   (Q4KM79    ), DUS12_HUMAN (Q9UNI6    ), DUS12_MOUSE (Q9D0T2    ), 
DUS12_RAT   (Q9JIM4    ), DUS14_BOVIN (Q17QM8    ), DUS14_HUMAN (O95147    ), 
DUS14_MOUSE (Q9JLY7    ), DUS15_HUMAN (Q9H1R2    ), DUS15_MOUSE (Q8R4V2    ), 
DUS16_HUMAN (Q9BY84    ), DUS18_BOVIN (Q5BIP9    ), DUS18_HUMAN (Q8NEJ0    ), 
DUS18_MOUSE (Q8VE01    ), DUS18_PONAB (Q5R8X2    ), DUS18_RAT   (Q6AXW7    ), 
DUS19_HUMAN (Q8WTR2    ), DUS19_MOUSE (Q8K4T5    ), DUS1A_XENLA (Q91790    ), 
DUS1B_ARATH (Q9M8K7    ), DUS1B_XENLA (Q90W58    ), DUS1_ARATH  (Q9ZR37    ), 
DUS1_HUMAN  (P28562    ), DUS1_MOUSE  (P28563    ), DUS1_RAT    (Q64623    ), 
DUS21_HUMAN (Q9H596    ), DUS21_MOUSE (Q9D9D8    ), DUS22_HUMAN (Q9NRW4    ), 
DUS22_MOUSE (Q99N11    ), DUS22_XENLA (Q6GQJ8    ), DUS22_XENTR (Q5XHB2    ), 
DUS23_HUMAN (Q9BVJ7    ), DUS23_MOUSE (Q6NT99    ), DUS26_BOVIN (Q17QJ3    ), 
DUS26_HUMAN (Q9BV47    ), DUS26_MOUSE (Q9D700    ), DUS26_PONAB (Q5R6H6    ), 
DUS26_RAT   (Q5FVI9    ), DUS27_HUMAN (Q5VZP5    ), DUS27_MOUSE (Q148W8    ), 
DUS28_HUMAN (Q4G0W2    ), DUS28_MOUSE (Q8BTR5    ), DUS2_HUMAN  (Q05923    ), 
DUS2_MOUSE  (Q05922    ), DUS3_HUMAN  (P51452    ), DUS3_MOUSE  (Q9D7X3    ), 
DUS3_PONAB  (Q5RD73    ), DUS4_CHICK  (Q9PW71    ), DUS4_HUMAN  (Q13115    ), 
DUS4_MOUSE  (Q8BFV3    ), DUS4_RAT    (Q62767    ), DUS5_HUMAN  (Q16690    ), 
DUS5_RAT    (O54838    ), DUS6_BOVIN  (Q2KJ36    ), DUS6_HUMAN  (Q16828    ), 
DUS6_MOUSE  (Q9DBB1    ), DUS6_RAT    (Q64346    ), DUS7_HUMAN  (Q16829    ), 
DUS7_MOUSE  (Q91Z46    ), DUS7_RAT    (Q63340    ), DUS8_HUMAN  (Q13202    ), 
DUS8_MOUSE  (O09112    ), DUS9_HUMAN  (Q99956    ), DUSK3_DROME (Q9VVW5    ), 
DUSP1_DICDI (Q55E39    ), DUSP2_DICDI (Q54R42    ), DUSP3_DICDI (Q55BI8    ), 
DUSP4_DICDI (Q54T76    ), DUSPR_DICDI (Q556Y8    ), DUSP_FOWPN  (Q9J592    ), 
DUSP_MYXVL  (Q85297    ), DUSP_RACVI  (P80994    ), DUSP_VACCC  (P20495    ), 
DUSP_VACCW  (P07239    ), DUSP_VAR67  (P33064    ), EAK6_CAEEL  (G5EGU2    ), 
EPM2A_CANLF (Q1M199    ), EPM2A_HUMAN (O95278    ), EPM2A_MOUSE (Q9WUA5    ), 
EPM2A_RAT   (Q91XQ2    ), FLP1_SCHPO  (Q9P7H1    ), HOPD2_PSESM (Q79LY0    ), 
IBR5_ARATH  (Q84JU4    ), IPHP_NOSCO  (Q05918    ), LAR_CAEEL   (Q9BMN8    ), 
LAR_DROME   (P16621    ), LSF2_ARATH  (Q9SRK5    ), MCE1_CAEEL  (Q17607    ), 
MCE1_DANRE  (Q6NY98    ), MCE1_HUMAN  (O60942    ), MCE1_MOUSE  (O55236    ), 
MKP1_ARATH  (Q9C5S1    ), MPL1_DICDI  (Q55CS7    ), MPL2_DICDI  (Q55CS8    ), 
MPL3_DICDI  (Q54Y32    ), MSG5_YEAST  (P38590    ), MTM1_BOVIN  (A6QLT4    ), 
MTM1_HUMAN  (Q13496    ), MTM1_MOUSE  (Q9Z2C5    ), MTM1_PONAB  (Q5R9S3    ), 
MTM1_XENLA  (Q52KU6    ), MTM1_XENTR  (Q5EB32    ), MTMR1_HUMAN (Q13613    ), 
MTMR1_MOUSE (Q9Z2C4    ), MTMR2_BOVIN (A6QLT2    ), MTMR2_CHICK (Q5ZIV1    ), 
MTMR2_DANRE (A0JMK5    ), MTMR2_HUMAN (Q13614    ), MTMR2_MOUSE (Q9Z2D1    ), 
MTMR2_PONAB (Q5REB9    ), MTMR4_HUMAN (Q9NYA4    ), MTMR4_MOUSE (Q91XS1    ), 
MTMR7_HUMAN (Q9Y216    ), MTMR7_MOUSE (Q9Z2C9    ), MTMR7_PONAB (Q5R6F6    ), 
PMP1_SCHPO  (O13453    ), PPS1_YEAST  (P38148    ), PRPTZ_MOUSE (B9EKR1    ), 
PTN11_CHICK (Q90687    ), PTN11_HUMAN (Q06124    ), PTN11_MOUSE (P35235    ), 
PTN11_RAT   (P41499    ), PTN12_HUMAN (Q05209    ), PTN12_MOUSE (P35831    ), 
PTN13_HUMAN (Q12923    ), PTN13_MOUSE (Q64512    ), PTN14_HUMAN (Q15678    ), 
PTN14_MOUSE (Q62130    ), PTN18_HUMAN (Q99952    ), PTN18_MOUSE (Q61152    ), 
PTN1_CHICK  (O13016    ), PTN1_HUMAN  (P18031    ), PTN1_MOUSE  (P35821    ), 
PTN1_RAT    (P20417    ), PTN20_HUMAN (Q4JDL3    ), PTN20_MOUSE (O55082    ), 
PTN20_RAT   (A1L1L3    ), PTN21_HUMAN (Q16825    ), PTN21_MOUSE (Q62136    ), 
PTN21_RAT   (Q62728    ), PTN22_HUMAN (Q9Y2R2    ), PTN22_MOUSE (P29352    ), 
PTN23_HUMAN (Q9H3S7    ), PTN23_MOUSE (Q6PB44    ), PTN23_RAT   (O88902    ), 
PTN2_HUMAN  (P17706    ), PTN2_MOUSE  (Q06180    ), PTN2_RAT    (P35233    ), 
PTN3_HUMAN  (P26045    ), PTN3_MOUSE  (A2ALK8    ), PTN4_HUMAN  (P29074    ), 
PTN4_MOUSE  (Q9WU22    ), PTN5_HUMAN  (P54829    ), PTN5_MOUSE  (P54830    ), 
PTN5_RAT    (P35234    ), PTN6_HUMAN  (P29350    ), PTN6_MOUSE  (P29351    ), 
PTN6_RAT    (P81718    ), PTN7_HUMAN  (P35236    ), PTN7_MOUSE  (Q8BUM3    ), 
PTN7_RAT    (P49445    ), PTN9_HUMAN  (P43378    ), PTN9_MOUSE  (O35239    ), 
PTN9_RAT    (Q641Z2    ), PTP10_DROME (P35992    ), PTP1_ARATH  (O82656    ), 
PTP1_CAEEL  (P28191    ), PTP1_DICDI  (P34137    ), PTP1_NPVOP  (O10274    ), 
PTP1_YEAST  (P25044    ), PTP2_CAEEL  (G5EC24    ), PTP2_DICDI  (P34138    ), 
PTP2_NPVOP  (O10273    ), PTP2_YEAST  (P29461    ), PTP3_CHLMO  (Q39491    ), 
PTP3_DICDI  (P54637    ), PTP3_YEAST  (P40048    ), PTP4_CAEEL  (P28192    ), 
PTP5_CAEEL  (P34442    ), PTP61_DROME (Q9W0G1    ), PTP69_DROME (P16620    ), 
PTP99_DROME (P35832    ), PTPC1_BOVIN (A7E379    ), PTPC1_DANRE (A1L1R5    ), 
PTPC1_HUMAN (A2A3K4    ), PTPC1_MOUSE (Q6NZK8    ), PTPH1_MDBVW (Q5I147    ), 
PTPH2_MDBVW (Q5I146    ), PTPH3_MDBVW (Q5I145    ), PTPH4_MDBVW (Q5I143    ), 
PTPH_AMEPV  (Q9EMX1    ), PTPH_MIMIV  (Q5UR74    ), PTPJ1_MDBVW (Q5I141    ), 
PTPJ2_MDBVW (Q5I139    ), PTPJ4_MDBVW (Q5I137    ), PTPM1_DROME (Q86BN8    ), 
PTPM1_HUMAN (Q8WUK0    ), PTPM1_MOUSE (Q66GT5    ), PTPM1_RAT   (P0C089    ), 
PTPN1_MDBVW (Q5I128    ), PTPR2_HUMAN (Q92932    ), PTPR2_MACNE (O02695    ), 
PTPR2_MOUSE (P80560    ), PTPR2_RAT   (Q63475    ), PTPRA_HUMAN (P18433    ), 
PTPRA_MOUSE (P18052    ), PTPRA_RAT   (Q03348    ), PTPRB_HUMAN (P23467    ), 
PTPRB_MOUSE (B2RU80    ), PTPRC_CYPCA (Q9IBD8    ), PTPRC_HUMAN (P08575    ), 
PTPRC_MOUSE (P06800    ), PTPRC_RAT   (P04157    ), PTPRD_HUMAN (P23468    ), 
PTPRD_MOUSE (Q64487    ), PTPRE_HUMAN (P23469    ), PTPRE_MOUSE (P49446    ), 
PTPRE_RAT   (B2GV87    ), PTPRF_BOVIN (A7MBJ4    ), PTPRF_DANRE (A4IFW2    ), 
PTPRF_HUMAN (P10586    ), PTPRF_MOUSE (A2A8L5    ), PTPRF_RAT   (Q64604    ), 
PTPRG_CHICK (Q98936    ), PTPRG_HUMAN (P23470    ), PTPRG_MOUSE (Q05909    ), 
PTPRH_HUMAN (Q9HD43    ), PTPRH_MOUSE (E9Q0N2    ), PTPRJ_CHICK (Q9W6V5    ), 
PTPRJ_HUMAN (Q12913    ), PTPRJ_MOUSE (Q64455    ), PTPRK_HUMAN (Q15262    ), 
PTPRK_MOUSE (P35822    ), PTPRM_HUMAN (P28827    ), PTPRM_MOUSE (P28828    ), 
PTPRN_BOVIN (P56722    ), PTPRN_HUMAN (Q16849    ), PTPRN_MOUSE (Q60673    ), 
PTPRN_RAT   (Q63259    ), PTPRO_HUMAN (Q16827    ), PTPRO_MOUSE (E9Q612    ), 
PTPRQ_HUMAN (Q9UMZ3    ), PTPRQ_MOUSE (P0C5E4    ), PTPRQ_RAT   (O88488    ), 
PTPRR_HUMAN (Q15256    ), PTPRR_MOUSE (Q62132    ), PTPRR_RAT   (O08617    ), 
PTPRS_HUMAN (Q13332    ), PTPRS_MOUSE (B0V2N1    ), PTPRS_RAT   (Q64605    ), 
PTPRT_HUMAN (O14522    ), PTPRT_MOUSE (Q99M80    ), PTPRU_CHICK (Q6YI48    ), 
PTPRU_DANRE (B3DK56    ), PTPRU_HUMAN (Q92729    ), PTPRU_MOUSE (B1AUH1    ), 
PTPRV_MOUSE (P70289    ), PTPRV_RAT   (Q64612    ), PTPRZ_HUMAN (P23471    ), 
PTPRZ_RAT   (Q62656    ), PTPR_CAEEL  (H2KZM6    ), PTPX_CANAW  (P43078    ), 
PTP_NPVAC   (P24656    ), PVH1_SCHPO  (O13632    ), PVH1_YEAST  (Q02256    ), 
PYP1_SCHPO  (P27574    ), PYP2_SCHPO  (P32586    ), PYP3_SCHPO  (P32587    ), 
SDP1_YEAST  (P40479    ), SPTP_SALPA  (Q5PEA9    ), SPTP_SALTI  (P74851    ), 
SPTP_SALTY  (P74873    ), SSH1_HUMAN  (Q8WYL5    ), SSH1_MOUSE  (Q76I79    ), 
SSH2_HUMAN  (Q76I76    ), SSH2_MOUSE  (Q5SW75    ), SSH3_HUMAN  (Q8TE77    ), 
SSH3_MOUSE  (Q8K330    ), SSH3_RAT    (Q5XIS1    ), SSH_DROME   (Q6NN85    ), 
SSH_XENLA   (Q6IVY4    ), STYXA_XENLA (Q4V7N3    ), STYXB_XENLA (Q5U593    ), 
STYX_HUMAN  (Q8WUJ0    ), STYX_MOUSE  (Q60969    ), STYX_PONAB  (Q5RDP3    ), 
TP4A1_HUMAN (Q93096    ), TP4A1_MACFA (Q9TSM6    ), TP4A1_MOUSE (Q63739    ), 
TP4A1_PONAB (Q5R7J8    ), TP4A1_RAT   (Q78EG7    ), TP4A2_HUMAN (Q12974    ), 
TP4A2_MOUSE (O70274    ), TP4A2_RAT   (Q6P9X4    ), TP4A3_BOVIN (A2VDT1    ), 
TP4A3_HUMAN (O75365    ), TP4A3_MOUSE (Q9D658    ), TP4AA_DICDI (Q54DU9    ), 
TP4AB_DICDI (Q86IL4    ), VF197_IIV3  (Q196Z3    ), VF197_IIV6  (Q91FX3    ), 
VHP1_CAEEL  (Q10038    ), Y669_CUPNH  (P40289    ), YAV4_XANCP  (P0A0W0    ), 
YAV4_XANEU  (P0A0W1    ), YK13_CAEEL  (P34337    ), YNBD_ECOLI  (P76093    ), 
YO42_CAEEL  (P34680    ), YOPH_YEREN  (P15273    ), YOPH_YERPS  (P08538    )
» more

UniProtKB/Swiss-Prot
False negative sequences
42 sequences

D1060_DICDI (Q1ZXG8    ), EAK5_CAEEL  (G5EGA9    ), LSF1_ARATH  (F4J117    ), 
MTM1_RAT    (Q6AXQ4    ), MTMR3_HUMAN (Q13615    ), MTMR3_MOUSE (Q8K296    ), 
MTMR3_RAT   (Q5PQT2    ), MTMR4_XENLA (Q7ZXF1    ), MTMR6_HUMAN (Q9Y217    ), 
MTMR6_MOUSE (Q8VE11    ), MTMRC_DANRE (A2BGG1    ), MTMRC_HUMAN (Q9C0I1    ), 
MTMRC_MOUSE (Q80TA6    ), MTMRC_PONAB (Q5R989    ), MTMRC_RAT   (Q5FVM6    ), 
MTMR_DICDI  (Q54GQ1    ), MYTM1_ARATH (F4J3T8    ), MYTM2_ARATH (F4JWB3    ), 
OCA1_ASHGO  (Q75B37    ), OCA1_CANAL  (Q59XY9    ), OCA1_CANGA  (Q6FSZ8    ), 
OCA1_DEBHA  (Q6BLZ8    ), OCA1_KLULA  (Q6CTE4    ), OCA1_PICGU  (A5DE24    ), 
OCA1_PICST  (A3LW52    ), OCA1_USTMA  (Q4P7L6    ), OCA1_YARLI  (Q6C4X9    ), 
OCA1_YEAS7  (A6ZRY1    ), OCA1_YEAST  (P50946    ), OCA6_YEAST  (Q12454    ), 
PTPD1_MDBVW (Q5I154    ), PTPH5_MDBVW (Q5I142    ), PTPJ3_MDBVW (Q5I138    ), 
PTPN2_MDBVW (Q5I127    ), PTPN3_MDBVW (Q5I124    ), SIW14_YEAST (P53965    ), 
STYL1_HUMAN (Q9Y6J8    ), Y1500_ARATH (Q9ZVN4    ), Y7071_DICDI (Q550K8    ), 
YKCA_CAEEL  (P42083    ), YMR1_YEAST  (P47147    ), YNF3_SCHPO  (Q9UUF3    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
27 sequences

PTP10_STYPL (P28202    ), PTP11_STYPL (P28203    ), PTP12_STYPL (P28204    ), 
PTP13_STYPL (P28205    ), PTP14_STYPL (P28206    ), PTP15_STYPL (P28207    ), 
PTP16_STYPL (P28208    ), PTP17_STYPL (P28209    ), PTP18_STYPL (P28210    ), 
PTP19_STYPL (P28211    ), PTP1_STYPL  (P28193    ), PTP20_STYPL (P28212    ), 
PTP21_STYPL (P28213    ), PTP22_STYPL (P28214    ), PTP23_STYPL (P28215    ), 
PTP24_STYPL (P28216    ), PTP25_STYPL (P28217    ), PTP26_STYPL (P28218    ), 
PTP27_STYPL (P28219    ), PTP2_STYPL  (P28194    ), PTP3_STYPL  (P28195    ), 
PTP4_STYPL  (P28196    ), PTP5_STYPL  (P28197    ), PTP6_STYPL  (P28198    ), 
PTP7_STYPL  (P28199    ), PTP8_STYPL  (P28200    ), PTP9_STYPL  (P28201    )
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

Y215_METJA  (Q57668    ), Y3520_METJA (Q60280    )

		
PDB
[Detailed view]
360 PDB

1A5Y; 1AAX; 1BZC; 1BZH; 1BZJ; 1C83; 1C84; 1C85; 1C86; 1C87; 1C88; 1ECV; 1EEN; 1EEO; 1FPR; 1FPZ; 1FQ1; 1G1F; 1G1G; 1G1H; 1G4U; 1G4W; 1G7F; 1G7G; 1GFY; 1GWZ; 1I57; 1I9S; 1I9T; 1J4X; 1JF7; 1JLN; 1KAK; 1KAV; 1L8G; 1L8K; 1LAR; 1LQF; 1LYV; 1M3G; 1MKP; 1NL9; 1NNY; 1NO6; 1NWE; 1NWL; 1NZ7; 1OEM; 1OEO; 1OES; 1OET; 1OEU; 1OEV; 1OHC; 1OHD; 1OHE; 1ONY; 1ONZ; 1P15; 1PA1; 1PA9; 1PH0; 1PTT; 1PTU; 1PTV; 1PTY; 1PXH; 1PYN; 1Q1M; 1Q6J; 1Q6M; 1Q6N; 1Q6P; 1Q6S; 1Q6T; 1QXK; 1R6H; 1RPM; 1RXD; 1SUG; 1T48; 1T49; 1T4J; 1V3A; 1VHR; 1WAX; 1WCH; 1WRM; 1X24; 1XBO; 1XM2; 1XXP; 1XXV; 1YFO; 1YGR; 1YGU; 1YN9; 1YPT; 1YTN; 1YTS; 1YTW; 1YZ4; 1ZC0; 1ZCK; 1ZCL; 1ZZW; 2A3K; 2A8B; 2AHS; 2AZR; 2B07; 2B3O; 2B49; 2B4S; 2BGD; 2BGE; 2BIJ; 2BV5; 2BZL; 2C46; 2C7S; 2CFV; 2CJZ; 2CM2; 2CM3; 2CM7; 2CM8; 2CMA; 2CMB; 2CMC; 2CNE; 2CNF; 2CNG; 2CNH; 2CNI; 2E0T; 2ESB; 2F6F; 2F6T; 2F6V; 2F6W; 2F6Y; 2F6Z; 2F70; 2F71; 2FH7; 2FJM; 2FJN; 2G59; 2G6Z; 2GJT; 2GP0; 2GWO; 2H02; 2H03; 2H04; 2H4G; 2H4K; 2H4V; 2HB1; 2HC1; 2HC2; 2HCM; 2HNP; 2HNQ; 2HVL; 2HXP; 2HY3; 2I1Y; 2I3R; 2I3U; 2I42; 2I4E; 2I4G; 2I4H; 2I5X; 2I75; 2IMG; 2J16; 2J17; 2JJD; 2MBC; 2NLK; 2NT2; 2NT7; 2NTA; 2NV5; 2NZ6; 2OC3; 2OOQ; 2OUD; 2P4D; 2P6X; 2PA5; 2PBN; 2PQ5; 2Q05; 2QBP; 2QBQ; 2QBR; 2QBS; 2QCJ; 2QCT; 2QDC; 2QDM; 2QDP; 2QEP; 2R0B; 2RF6; 2SHP; 2VEU; 2VEV; 2VEW; 2VEX; 2VEY; 2WGP; 2Y96; 2ZMM; 2ZN7; 3A5J; 3A5K; 3B7O; 3BLT; 3BLU; 3BM8; 3BRH; 3CM3; 3CWE; 3D42; 3D44; 3D9C; 3EAX; 3EB1; 3EU0; 3EZZ; 3F81; 3F99; 3F9A; 3F9B; 3H2X; 3I7Z; 3I80; 3LJ8; 3MOW; 3NME; 3O4S; 3O4T; 3O4U; 3O5X; 3OLR; 3OMH; 3PS5; 3QCB; 3QCC; 3QCD; 3QCE; 3QCF; 3QCG; 3QCH; 3QCI; 3QCJ; 3QCK; 3QCL; 3QCM; 3QCN; 3QKP; 3QKQ; 3RGO; 3RGQ; 3RZ2; 3S3E; 3S3F; 3S3H; 3S3K; 3S4E; 3SME; 3SR9; 3U96; 3ZM0; 3ZM1; 3ZM2; 3ZM3; 3ZMP; 3ZMQ; 3ZV2; 4B04; 4BJO; 4BPC; 4D3P; 4D3Q; 4D3R; 4DGP; 4DGX; 4ERC; 4GE2; 4GE5; 4GE6; 4GFU; 4GFV; 4GRY; 4GRZ; 4GS0; 4GWF; 4H1O; 4H34; 4HJP; 4HJQ; 4HRF; 4I8N; 4ICZ; 4IKC; 4J51; 4JMJ; 4JMK; 4JNB; 4KI9; 4KYQ; 4KYR; 4MBB; 4NND; 4NWF; 4NWG; 4NYH; 4OHD; 4OHE; 4OHH; 4OHI; 4OHL; 4PVG; 4PYH; 4QAH; 4QAP; 4QBE; 4QBW; 4QUM; 4QUN; 4RDD; 4RH5; 4RH9; 4RHG; 4RI4; 4RI5; 4S0G; 4WOH; 4Y14; 4Y2E; 4YAA; 4YR8; 4Z6B; 4ZI4; 4ZN5; 4ZRT; 5AWX; 5EHP; 5EHR; 5GTJ; 5I6V; 5IBM; 5IBS; 5J8R
» more

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