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Entry: PS50090

General information about the entry

Entry name [info] MYB_LIKE
Accession [info] PS50090
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED; 01-FEB-2007 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00037
Associated ProRule [info] PRU00133

Name and characterization of the entry

Description [info] Myb-like domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=52;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=52;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.3846165; R2=0.0116124; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=483; N_SCORE=5.9875995; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=301; N_SCORE=3.8741427; MODE=1; TEXT='R?';
/DEFAULT: D=-20; I=-20; B1=-40; E1=-40; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='R'; M= -7,  1,-24, -2, -1,-21, -6, -2,-22,  7,-19,-11,  7,-15,  0, 12,  0, -4,-17,-27,-13, -2;
/M: SY='P'; M= -5, -9,-28, -6,  2,-24,-14,-13,-15, -4,-21,-12, -8, 23, -2, -8, -1, -4,-15,-28,-20, -3;
/M: SY='N'; M= -9,  7,-26,  8,  6,-22, -6, -2,-24,  3,-23,-15,  9, -8,  0,  2,  1, -6,-21,-28,-14,  2;
/M: SY='L'; M= -7,-14,-23,-15, -9,-11,-22, -8, -2, -4,  1,  1,-11,-17, -7,  0,-11, -7,  0,-22, -6, -9;
/M: SY='K'; M= -5,  2,-22, -3,  0,-22,-11, -8,-19, 13,-21,-11,  7,-15,  1, 11, -1, -4,-14,-26,-14,  0;
/M: SY='R'; M= -9, -6,-28, -6,  3,-23,-12, -8,-27, 24,-23,-11, -2,-10,  5, 30, -5, -7,-19,-21,-13,  2;
/M: SY='G'; M= -2, -2,-23, -3, -7,-23, 21,-13,-26, -6,-23,-14,  4,-16, -9, -6,  5, -4,-18,-27,-21, -8;
/M: SY='P'; M=  0, -3,-22, -4,  0,-21,-13,-10,-18,  2,-20,-13,  2,  5, -3,  1,  3, -1,-16,-28,-16, -3;
/M: SY='W'; M=-19,-38,-43,-40,-30, 21,-23,-28,-13,-22,-13,-15,-36,-30,-23,-21,-36,-26,-22,117, 28,-22;
/M: SY='T'; M=  1, -1,-13, -5, -5,-15,-13,-16,-14, -8,-17,-13,  1, -6, -7,-10, 21, 31, -5,-33,-14, -6;
/M: SY='E'; M= -7,  0,-27,  2, 10,-24,-18, -4,-20, 10,-19,-10, -2, -3,  6,  5, -4, -7,-16,-26,-13,  7;
/M: SY='E'; M= -6, 10,-26, 17, 34,-29,-16, -3,-26,  5,-21,-18,  1, -2, 12, -3,  3, -5,-23,-31,-19, 23;
/M: SY='E'; M=-11, 14,-30, 24, 55,-31,-19,  0,-31,  9,-21,-21,  2, -1, 19, -1,  0,-10,-30,-31,-20, 37;
/M: SY='D'; M=-14, 25,-27, 36, 19,-30,-14, -2,-27,  0,-20,-18,  8,-10,  4, -7,  0, -5,-21,-34,-16, 11;
/M: SY='E'; M= -9,  1,-27,  3, 16,-21,-20, -4,-16,  4,-10, -7, -2,-12, 13,  4, -5, -8,-17,-24,-11, 14;
/M: SY='M'; M=  0,-13,-23,-17, -6,-11,-21,-13, -1, -1,  0,  3,-11,-16, -3, -3, -9, -6, -2,-21, -8, -5;
/M: SY='L'; M= -9,-30,-22,-33,-23, 12,-32,-23, 25,-29, 38, 18,-27,-27,-22,-22,-26, -9, 15,-18,  1,-23;
/M: SY='I'; M= -7,-21,-23,-24,-14, -4,-29,-18, 14,-11, 10,  8,-18,-19,-12,-10,-15, -7, 11,-20, -1,-15;
/M: SY='E'; M= -5,  4,-24,  4, 10,-24,-15, -2,-22, 10,-18,-11,  3,-12,  7,  8,  1, -2,-18,-27,-12,  8;
/M: SY='L'; M=  2,-20,-20,-24,-18,  1,-14,-14,  4,-20, 15,  5,-18,-23,-16,-18,-14, -7,  2,-14,  1,-17;
/M: SY='V'; M= -5,-21,-17,-24,-19, -6,-28, -4, 13,-16,  6,  7,-17,-24,-15,-11,-13, -7, 17,-25, -2,-19;
/M: SY='E'; M= -4,  1,-25, -1, 12,-24,-14, -1,-21, 11,-19, -8,  3,-12, 12, 11,  0, -6,-18,-26,-13, 11;
/I:         MD=-15;
/M: SY='E'; M= -7,  0,-25, -1, 13,-21,-18, -5,-16,  9,-14, -7,  0,-12,  8,  5, -3, -4,-15,-25,-12, 10; D=-1;
/I:         MD=-15;
/M: SY='H'; M=-13,-12,-23,-15,-12,  4,-22, 13, -3,-13,  5,  6, -7,-24, -8, -9,-14, -9, -7,-13, 13,-11; D=-1;
/I:         MD=-15;
/M: SY='G'; M= -2, -7,-27, -5,-13,-25, 39,-16,-29,-14,-24,-16, -2, -8,-14,-16, -1,-15,-23,-20,-23,-14; D=-1;
/I:         I=-4; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='E'; M= -4, -1,-14, -1,  3,-14, -8, -1,-13, -1,-11, -6, -1, -3,  1, -3,  0,  0,-11,-18, -8,  1; D=-1;
/I:         DM=-15;
/M: SY='N'; M= -7,  5,-25,  0, -4,-21,  3, -5,-18, -6,-19,-12, 11,-10, -5, -7,  0, -5,-19,-28,-16, -6;
/M: SY='R'; M=-10,  4,-18,  2,  0,-20,-13, -2,-21,  5,-16,-10,  8,-18,  4, 13, -3, -7,-19,-28,-13,  1;
/M: SY='W'; M=-20,-39,-49,-39,-30, 11,-20,-28,-19,-20,-19,-19,-39,-30,-20,-20,-39,-29,-29,146, 32,-20;
/M: SY='S'; M=  0,  2,-21,  2,  5,-22,-10, -6,-21,  5,-20,-14,  4,-13,  2,  6,  7,  2,-14,-28,-14,  3;
/M: SY='E'; M= -2, -3,-22, -2,  8,-17,-17,-11,-14,  2,-11, -9, -5,-13,  0, -1, -1, -3, -9,-26,-13,  4;
/M: SY='I'; M= -8,-30,-25,-37,-29,  1,-37,-28, 43,-28, 21, 19,-23,-23,-21,-27,-19, -8, 31,-22, -2,-29;
/M: SY='A'; M= 27, -8,-15,-12, -5,-21, -1,-16,-15, -8,-18,-14, -5, -2, -6,-15, 15,  3, -7,-27,-20, -6;
/M: SY='K'; M= -4,  0,-25,  1,  8,-24,-13, -3,-22, 12,-20,-10,  1,-10,  6, 10,  0, -5,-17,-26,-13,  6;
/I:         MD=-18;
/M: SY='H'; M=-11, -6,-22, -8, -4,-12,-17, 12,-15,  2,-10, -2, -1,-19,  1,  7, -8, -9,-15,-20,  2, -3; D=-3;
/I:         MD=-18;
/M: SY='L'; M= -2,-24,-18,-29,-21,  9,-24,-17, 16,-22, 23, 17,-22,-24,-18,-18,-17, -6, 13,-18,  1,-19; D=-3;
/I:         I=-5; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='P'; M= -8,-14,-29,-11, -6,-16, -2,-13,-15,-10,-13, -9,-11, 16, -9,-13, -9,-10,-18,-19,-12,-10; D=-3;
/I:         DM=-18;
/M: SY='N'; M= -6,  3,-23, -1, -6,-20,  8, -4,-23, -4,-20,-13, 10,-17, -5, -2,  3, -2,-19,-27,-15, -6;
/M: SY='R'; M=-18, -8,-30, -8,  2,-22,-20,  1,-30, 32,-22,-10,  0,-18, 10, 60,-10, -9,-20,-20, -9,  2;
/M: SY='T'; M= -1, -2,  0, -9, -9,-15,-14,-16,-13,-11,-16,-11,  1,-13, -9,-10, 16, 24, -6,-34,-15, -9;
/M: SY='D'; M= -6,  4,-29, 10,  2,-27,  3,-11,-28, -4,-26,-20,  0,  4, -6, -9,  0, -7,-23,-24,-18, -3;
/M: SY='K'; M= -8,  6,-24,  1,  5,-20,-16, -4,-16, 11,-19, -9, 11,-15,  4,  6, -2, -3,-15,-25,-12,  4;
/M: SY='Q'; M= -2,  6,-23,  8, 16,-29,-13, -1,-21,  3,-21,-10,  4,-10, 22,  0,  8, -2,-21,-28,-15, 19;
/M: SY='C'; M= -9,-23, 67,-32,-29,-12,-32,-29, -5,-29, -6, -7,-21,-34,-27,-28,-12, -8,  6,-40,-20,-29;
/M: SY='R'; M=-12, -7,-28, -8,  3,-22,-21, -3,-21, 26,-18, -4, -3,-15, 11, 32, -9, -9,-16,-20, -8,  5;
/M: SY='N'; M=-10,  9,-24,  7,  5,-13,-15,  6,-15, -5,-10, -9, 10,-17, -1, -6, -3, -6,-17,-27, -5,  2;
/M: SY='R'; M=-18,-10,-30,-10, -2,-12,-22,  8,-24, 21,-18, -7, -3,-20,  7, 39,-12,-11,-19,-11,  7, -1;
/M: SY='W'; M=-19,-34,-41,-36,-28, 23,-23,-21,-14,-20,-12,-14,-33,-29,-21,-18,-32,-22,-21,104, 36,-21;
/M: SY='N'; M=-10,  3,-23, -2,  2,-17,-17,  2,-14,  3,-12, -6,  9,-17,  5,  8, -4, -4,-16,-26, -9,  2;
/M: SY='N'; M= -6,  7,-21,  0,  1,-19,-11, -6,-18,  7,-20,-12, 14,-15,  2,  7,  4,  3,-15,-29,-14,  1;
/M: SY='Y'; M=-11,-17,-22,-19,-16,  3,-26,  7,  4,-16,  8,  6,-14,-25,-10,-11,-14, -5,  1,-11, 18,-15;
/M: SY='L'; M= -8,-23,-21,-26,-19,  5,-27,-16, 15,-20, 24, 13,-21,-23,-17,-16,-20, -8, 10,-19,  1,-19;
/I:         E1=0; IE=-105; DE=-105;
» more

Post-processing [info]

COMPETES_HIT_WITH PS51294(4); PS51293

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 91 in 76 different sequences
Number of true positive hits 85 in 70 different sequences
Number of 'unknown' hits 0
Number of false positive hits 6 in 6 different sequences
Number of false negative sequences 52
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 93.41 %
Recall (true positives / (true positives + false negatives)) 62.04 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, PS_Langendijk_Genevaux
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 3
Feature key [info] DOMAIN
Feature description [info] myb-like
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
70 sequences

AEF1_GIBZE  (Q4IB96    ), ASR3_ARATH  (Q8VZ20    ), BAS1_YEAST  (P22035    ), 
DMTF1_DANRE (Q6DG03    ), DMTF1_HUMAN (Q9Y222    ), DMTF1_MOUSE (Q8CE22    ), 
DMTF1_RAT   (Q66HG1    ), DOM_DROME   (Q9NDJ2    ), EAF11_USTMA (Q4P209    ), 
EAF1A_ARATH (F4J7T3    ), EAF1B_ARATH (F4J7T2    ), EAF1_ASHGO  (Q756L0    ), 
EAF1_ASPFU  (Q4WP03    ), EAF1_CANAL  (Q5A119    ), EAF1_DEBHA  (Q6BI82    ), 
EAF1_EMENI  (Q5B4Q8    ), EAF1_KLULA  (Q6CMB8    ), EAF1_NEUCR  (Q7SBU6    ), 
EAF1_YARLI  (Q6C7K8    ), EAF1_YEAST  (Q06337    ), EAF_SCHPO   (O59773    ), 
EP400_HUMAN (Q96L91    ), EP400_MOUSE (Q8CHI8    ), ETA2_SCHPO  (O14108    ), 
ETC3_ARATH  (Q9M157    ), GON4L_HUMAN (Q3T8J9    ), GON4L_MOUSE (Q9DB00    ), 
GON4L_RAT   (Q535K8    ), GSTT2_ARATH (Q8L727    ), GSTT3_ARATH (Q9FHE1    ), 
GTL1_ARATH  (Q9C882    ), GTL2_ARATH  (Q8H181    ), MYB1_PLAF7  (Q8IEF6    ), 
MYBC_DICDI  (Q54TN2    ), MYBM_DICDI  (Q55GK3    ), MYBN_DICDI  (Q54CT1    ), 
MYBO_DICDI  (Q54FL0    ), MYBR_DICDI  (Q54DP7    ), MYBS1_ORYSI (B8A9B2    ), 
MYBS1_ORYSJ (Q8LH59    ), MYBT_DICDI  (Q54DQ3    ), MYBV_DICDI  (Q54X08    ), 
MYBW_DICDI  (Q55BV7    ), MYBZ_DICDI  (Q54Q45    ), MYB_AVIMB   (P01104    ), 
MYPOP_HUMAN (Q86VE0    ), MYPOP_MOUSE (Q8R4U1    ), MYPOP_XENLA (Q08B72    ), 
NCOR1_CAEEL (P34333    ), NSI1_YEAST  (Q12457    ), PIE1_ARATH  (Q7X9V2    ), 
PTL_ARATH   (Q9LZS0    ), REB1_YEAST  (P21538    ), RPI1_YEAST  (P23250    ), 
RSFA_BACSU  (P39650    ), SNPC4_CAEEL (P91868    ), SNPC4_HUMAN (Q5SXM2    ), 
SNPC4_MOUSE (Q8BP86    ), TAY1_YARLI  (Q6C9I6    ), TCL1_ARATH  (D3GKW6    ), 
TGT1_ARATH  (Q9FX53    ), TGT2_ARATH  (Q39117    ), TGT3A_ARATH (Q9SDW0    ), 
TGT3B_ARATH (O80450    ), TGT4_ARATH  (Q9LU92    ), TRY_ARATH   (Q8GV05    ), 
TTF1_HUMAN  (Q15361    ), TTF1_MOUSE  (Q62187    ), UBF1A_XENLA (P25979    ), 
YMA9_CAEEL  (P34454    )
» more

UniProtKB/Swiss-Prot
False negative sequences
52 sequences

ASIL1_ARATH (Q9SYG2    ), ASIL2_ARATH (Q9LJG8    ), BDP1_HUMAN  (A6H8Y1    ), 
BDP1_MOUSE  (Q571C7    ), CEF1_ASHGO  (Q756C3    ), CEF1_KLULA  (Q6CU65    ), 
CHD6_HUMAN  (Q8TD26    ), CHD6_MOUSE  (A3KFM7    ), CHD6_RAT    (D3ZA12    ), 
CPC_ARATH   (O22059    ), DMAP1_DROME (Q7K3D8    ), EAF1_CRYNB  (P0CO99    ), 
EAF1_CRYNJ  (P0CO98    ), ETC1_ARATH  (Q9LNI5    ), ETC2_ARATH  (Q84RD1    ), 
KNL2_CAEEL  (O44548    ), LIMYB_ARATH (Q9FFJ8    ), MSD1_HUMAN  (Q6ZTZ1    ), 
MSD1_MOUSE  (Q8BIL2    ), MSD2_CHICK  (Q5ZHX5    ), MSD2_HUMAN  (Q6P1R3    ), 
MSD2_MOUSE  (Q6NZR2    ), MSD3_BOVIN  (Q0III0    ), MSD3_HUMAN  (Q96H12    ), 
MSD3_MOUSE  (Q9CR78    ), MSD3_XENLA  (Q7ZYM8    ), MSD3_XENTR  (Q28J92    ), 
MSD4_BOVIN  (Q2KJB9    ), MSD4_HUMAN  (Q8NCY6    ), MSD4_MOUSE  (Q91YU3    ), 
MSD4_RAT    (Q501L3    ), MSD4_XENTR  (Q6GLA1    ), MYBB_DICDI  (O15816    ), 
MYBL_DICDI  (Q54NA6    ), MYBU_DICDI  (Q54QC0    ), MYBY_DICDI  (Q54PP6    ), 
REB1_KLULA  (Q05950    ), RTF_SCHPO   (Q9UUI6    ), TAZ1_SCHPO  (P79005    ), 
TCL2_ARATH  (B3H4X8    ), TE2IP_BOVIN (Q0VCT3    ), TE2IP_CHICK (Q7T0L4    ), 
TE2IP_DANRE (Q6NYJ3    ), TE2IP_HUMAN (Q9NYB0    ), TE2IP_MACFA (Q4R4I0    ), 
TE2IP_MOUSE (Q91VL8    ), TE2IP_RAT   (Q5EAN7    ), TE2IP_XENLA (Q71M44    ), 
TE2IP_XENTR (B8QB46    ), TERB1_DANRE (Q1LX29    ), TERB1_HUMAN (Q8NA31    ), 
TERB1_MOUSE (Q8C0V1    )
» more

UniProtKB/Swiss-Prot
False positive sequences
6 sequences

DNJC1_MOUSE (Q61712    ), DNJC2_BOVIN (Q1RMH9    ), MYB_DROME   (P04197    ), 
SWC4_ASPFU  (Q4WNY4    ), SWC4_CANAL  (Q5AAJ7    ), SWC4_EMENI  (Q5B4T5    )
» more

PDB
[Detailed view]
4 PDB

1H8A; 1UG2; 2EBI; 2JMW

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