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PROSITE entry PS50126


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50126
Entry name [info] S1
Accession [info] PS50126
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50126
Associated ProRule [info] PRU00180

Name and characterization of the entry

Description [info] S1 domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=70;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=65;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.3473001; R2=0.0224986; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2886.4855957; R2=3.7428572; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=318; H_SCORE=4077; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=230; H_SCORE=3747; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-70; E1=-70; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 1'309 in 1'040 different sequences
Number of true positive hits 1'309 in 1'040 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 110
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.25 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 14
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] S1 motif
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1040 sequences

CSL4_SACS2  (Q980J9), CSL4_SCHPO  (O59821), DEAH5_ARATH (Q38953), 
» more

UniProtKB/Swiss-Prot
False negative sequences
110 sequences

CSL4_ARCFU  (O30033), EXOS1_HUMAN (Q9Y3B2), EXOS1_MOUSE (Q9DAA6), 
» more

PDB
[Detailed view]
278 PDB

1E3H; 1E3P; 1GO3; 1K0R; 1KL9; 1LUZ; 1Q46; 1Q8K; 1SLJ; 1SMX; 1SN8; 1SRO;
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