Entry: PS50174

General information about the entry

Entry name [info] G_PATCH
Accession [info] PS50174
Entry type [info] MATRIX
Date [info] JAN-2002 (CREATED); OCT-2013 (DATA UPDATE); JUN-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC50174
Associated ProRule [info] PRU00092

Name and characterization of the entry

Description [info] G-patch domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=47;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=43;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.0889000; R2=0.0170978; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1365.4576416; R2=4.1952276; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=434; H_SCORE=3186; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=317; H_SCORE=2695; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='T'; M= -4, -4,-23, -4, -2,-19,-12,-11,-13, -5,-15,-10, -5, -2, -4, -9,  2,  5,-10,-26,-12, -4;
/M: SY='E'; M= -6,  8,-23,  9, 10,-25, -2, -4,-24,  2,-23,-13,  9,-12,  5,  1,  8, -2,-20,-31,-18,  7;
/M: SY='N'; M= -5, 11,-24,  6, -3,-24,  7, -7,-25, -4,-28,-19, 19, -3, -5, -5,  8,  0,-24,-32,-22, -5;
/M: SY='I'; M= -8,-23,-23,-27,-20,  1,-30,-23, 16,-15,  6,  6,-19,-11,-18,-14,-13, -3, 15,-21, -4,-21;
/M: SY='G'; M=  8,-10,-24,-11,-15,-25, 43,-19,-28,-17,-23,-16, -3,-18,-17,-19,  4,-12,-17,-23,-26,-16;
/M: SY='H'; M= -9, -8,-23,-11, -6, -5,-14, 10,-13, -7,-10, -2, -3,-19, -1, -4, -5, -5,-12,-17,  5, -4;
/M: SY='K'; M= -5, -2,-20, -3,  6,-28,-17, -7,-26, 25,-24,-10, -1,-13, 13, 23, -4, -8,-19,-23,-13,  8;
/M: SY='M'; M= -9,-24,-20,-29,-20,  5,-26,-13, 19,-20, 28, 31,-23,-24,-11,-16,-21, -9, 11,-20,  0,-15;
/M: SY='L'; M=-10,-25,-20,-29,-18,  4,-26,-11, 18,-20, 35, 35,-25,-25, -8,-15,-25,-10,  8,-20,  0,-13;
/M: SY='Q'; M= -3, -7,-19, -7,  7,-20,-19, -8,-12, -2, -6, -2, -8,-11,  9, -1, -5, -5,-11,-25,-13,  7;
/M: SY='K'; M= -1,  2,-24,  0,  4,-27, -9, -9,-26, 23,-26,-13,  4,-12,  5, 15,  2, -3,-18,-25,-14,  4;
/M: SY='M'; M=-10,-17,-16,-24,-16,  0,-18, -2,  6,-10,  8, 31,-15,-21,  0, -8,-13, -6,  0,-16,  4, -9;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='W'; M=-20,-34,-43,-35,-27, 18,-23,-18,-13,-19,-11,-13,-34,-30,-19,-18,-34,-24,-22,109, 40,-20;
/M: SY='K'; M= -9, -5,-26, -5,  5,-20,-19, -8,-21, 23,-19, -9, -2,-13,  5, 23, -3, -1,-14,-22, -8,  3;
/I:         I=-6; MD=-32;
/M: SY='E'; M= -7, -4,-30,  4, 25,-27,-15, -9,-22,  2,-21,-16, -8, 24,  6, -7, -4, -9,-23,-27,-21, 14; D=-6;
/I:         I=-6; MI=-32; IM=-32; DM=-32;
/M: SY='G'; M=  0, -7,-29, -7,-16,-29, 61,-18,-38,-18,-30,-20,  3,-19,-17,-18,  2,-17,-29,-22,-29,-16;
/M: SY='Q'; M=-10,  0,-27,  0, 12,-27,-14,  1,-21, 11,-18, -2, -1,-11, 20,  8, -3, -6,-20,-24,-11, 16;
/M: SY='G'; M=  0,-10,-29,-10,-20,-29, 66,-20,-39,-20,-29,-20,  0,-20,-20,-20,  1,-17,-29,-20,-29,-20;
/M: SY='L'; M=-10,-30,-21,-31,-21,  9,-31,-21, 24,-30, 46, 20,-29,-29,-20,-21,-29,-10, 13,-20,  0,-21;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='K'; M= -6, -9,-24, -9, -1,-17,-19, -6,-15, 14,-12, -5, -6,-13,  2, 11, -6, -5,-11,-21, -5, -1;
/M: SY='N'; M= -4,  6,-23,  3,  4,-24, -7,  4,-23,  5,-23,-13, 12,-11,  6,  5,  5, -4,-21,-29,-14,  4;
/M: SY='E'; M= -5,  2,-23,  3, 15,-24, -2,  3,-27, -1,-21,-15,  5, -8,  3, -1,  1, -9,-24,-29,-17,  8;
/M: SY='Q'; M=-10,  5,-27,  7, 13,-31,-17,  1,-19,  8,-20, -6,  3, -7, 26,  4, -1, -7,-21,-26,-13, 19;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='G'; M=  1, -6,-29, -7,-13,-29, 53,-17,-37,-13,-29,-19,  2,-18,-15,-15,  0,-17,-28,-21,-27,-14;
/M: SY='I'; M=-10,-15,-26,-20,-15, -9,-28,-14, 18,-17,  8, 10,-10,-19, -6,-13,-12, -8,  7,-24, -4,-13;
/M: SY='K'; M=  2,-10,-21,-13, -7,-17,-18,-15, -6,  3,-11, -5, -7, -9, -5,  1, -2, -1, -1,-25,-13, -7;
/M: SY='B'; M= -8, 10,-23,  9,  8,-20,-15,  2,-18, -2,-16,-11,  9,-13,  5, -4,  3,  1,-17,-30,-11,  6;
/M: SY='P'; M= -2,-15,-31,-10, -2,-26,-16,-18,-16, -6,-25,-16,-12, 49, -7,-13, -1, -4,-20,-29,-24, -8;
/M: SY='I'; M= -9,-25,-23,-28,-20,  0,-31,-18, 24,-21, 16, 11,-19,-23,-17,-16,-16, -7, 19,-23, -2,-21;
/M: SY='E'; M= -4, -3,-26, -2,  8,-24,-12, -4,-18,  5,-16, -7, -2, -5,  6,  2, -3, -8,-17,-25,-14,  6;
/M: SY='A'; M= 11,-16,-11,-20,-17,-10, -9,-20, -2,-12, -3, -3,-15,-20,-16,-15, -1,  1,  8,-22,-10,-17;
/M: SY='E'; M= -8, -3,-28, -2, 14,-22,-11, -6,-18,  8,-18,-10, -3,-11,  4,  2, -4, -8,-16,-24,-11,  8;
/M: SY='V'; M= -2,-11,-21,-12,-10,-15,-14,-18,  1, -8, -6, -2, -9,-18, -9,-12, -2, -3,  5,-27,-12,-11;
/M: SY='R'; M= -8, -2,-17, -7, -3,-17,-17, -9,-14,  3,-16, -9,  4,-18,  2,  6,  0,  0,-12,-20,-11, -1;
/I:         I=-4; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='D'; M= -6,  2,-23,  3,  3,-22,-13, -6,-18,  1,-15, -8,  0,-10,  2,  0,  1,  1,-13,-28,-13,  2;
/M: SY='K'; M= -3,  8,-24,  9,  4,-24, -5, -7,-27, 10,-24,-16,  8,-13,  1,  7,  1, -6,-20,-26,-15,  2;
/M: SY='R'; M=-13, -2,-28, -5, -3,-21, -5, -3,-25, 13,-22,-11,  7,-19,  6, 26, -6,-10,-21,-16,-10,  0;
/M: SY='K'; M=  0, -9,-23, -9,  1,-15, -8,-13,-18,  3,-14,-10, -7, -9, -4,  3, -3, -4,-12,-22,-13, -2;
/M: SY='G'; M=  1, -4,-27, -3,-11,-29, 50,-17,-36,-16,-29,-20,  2,-17,-14,-17,  6,-13,-26,-24,-27,-13;
/M: SY='L'; M= -9,-25,-20,-28,-20, 12,-29,-21, 14,-20, 22, 10,-22,-26,-20,-13,-18, -5, 13,-18,  1,-20;
/M: SY='G'; M= -4, -5,-30, -3,-10,-28, 42,-16,-32,-12,-25,-17,  0,-18,-13,-12, -2,-17,-25,-22,-25,-12;
/M: SY='A'; M=  8,-13,-14,-19,-11, -5,-17, -7, -5,-11, -6, -4,-11,-19, -8,-14, -6, -7, -3, -9,  3,-10;
/M: SY='S'; M=  0, -2,-22, -2, -1,-13, -6,-10,-18, -3,-17,-13,  0,-12, -5, -5,  2, -4,-12,-23,-11, -3;
/M:         M= -2,-10,-23,-11, -5,-15, -1,-14,-16,  0, -9, -4, -7,-17, -7, -3, -5, -8,-11,-22,-13, -6;
/M: SY='P'; M= -8, -2,-27,  2,  8,-23,-17,-10,-18,  4,-19,-11, -4,  9,  1, -1,  0, -2,-17,-29,-17,  3;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_08 which contains 551'987 sequence entries.


Total number of hits 194 in 194 different sequences
Number of true positive hits 194 in 194 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.98 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, CJA_Sigrist
Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] G-patch
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
194 sequences

AGGF1_HUMAN (Q8N302    ), AGGF1_MOUSE (Q7TN31    ), C3H18_ORYSJ (Q6K687    ), 
C3H22_ARATH (Q9SK49    ), CHERP_HUMAN (Q8IWX8    ), CHERP_MOUSE (Q8CGZ0    ), 
CMTR1_AILME (D2HRF1    ), CMTR1_BOVIN (A2VE39    ), CMTR1_DANRE (Q803R5    ), 
CMTR1_HUMAN (Q8N1G2    ), CMTR1_MOUSE (Q9DBC3    ), CMTR1_PONAB (Q5R981    ), 
CMTR1_RAT   (Q5U2Z5    ), CMTR1_XENLA (Q6GQ76    ), DR111_ARATH (P42698    ), 
GAG_IPMA    (P11365    ), GPAN1_CAEEL (Q09655    ), GPAN1_DROME (Q9V7A7    ), 
GPAN1_HUMAN (O95872    ), GPAN1_MOUSE (Q61858    ), GPKOW_DANRE (Q90X38    ), 
GPKOW_HUMAN (Q92917    ), GPKOW_MOUSE (Q56A08    ), GPKOW_XENLA (Q6NU07    ), 
GPT11_BOVIN (Q2KI19    ), GPT11_DANRE (Q6DGZ0    ), GPT11_HUMAN (Q8N954    ), 
GPT11_MOUSE (Q3UFS4    ), GPT11_XENTR (Q6DF57    ), GPTC1_BOVIN (Q24K12    ), 
GPTC1_CAEEL (Q21827    ), GPTC1_DROME (Q9VUA0    ), GPTC1_HUMAN (Q9BRR8    ), 
GPTC1_MOUSE (Q9DBM1    ), GPTC2_HUMAN (Q9NW75    ), GPTC2_MOUSE (Q7TQC7    ), 
GPTC3_HUMAN (Q96I76    ), GPTC3_MOUSE (Q8BIY1    ), GPTC4_BOVIN (Q2KJE1    ), 
GPTC4_HUMAN (Q5T3I0    ), GPTC4_MOUSE (Q3TFK5    ), GPTC4_RAT   (Q566R3    ), 
GPTC4_XENLA (Q4V842    ), GPTC4_XENTR (Q6P859    ), GPTC8_HUMAN (Q9UKJ3    ), 
GPTC8_MOUSE (A2A6A1    ), MOS2_ARATH  (Q9C801    ), MOS2_CAEEL  (Q21924    ), 
MTR1A_CAEBR (A8XYX2    ), MTR1B_CAEBR (A8XYX3    ), MTR1_CAEEL  (Q9NAA5    ), 
MTR1_DICDI  (Q54WR1    ), MTR1_DROME  (Q9W4N2    ), NKRF_HUMAN  (O15226    ), 
NKRF_MOUSE  (Q8BY02    ), PINX1_HUMAN (Q96BK5    ), PINX1_MOUSE (Q9CZX5    ), 
PINX1_RAT   (A4L691    ), POK9_HUMAN  (P63128    ), PXR1_AJECN  (A6R371    ), 
PXR1_ASHGO  (Q751P0    ), PXR1_ASPCL  (A1CD56    ), PXR1_ASPFU  (Q4WG40    ), 
PXR1_ASPNC  (A2R156    ), PXR1_ASPOR  (Q2UDW7    ), PXR1_ASPTN  (Q0CU52    ), 
PXR1_BOTFB  (A6RIE1    ), PXR1_CANAL  (Q5A660    ), PXR1_CANGA  (Q6FTR8    ), 
PXR1_CHAGB  (Q2HFA6    ), PXR1_COCIM  (Q1DQE9    ), PXR1_DEBHA  (Q6BUE3    ), 
PXR1_KLULA  (Q6CTA7    ), PXR1_LODEL  (A5E4P1    ), PXR1_MAGO7  (A4R0T9    ), 
PXR1_NEOFI  (A1DC33    ), PXR1_NEUCR  (Q7SHT5    ), PXR1_PHANO  (Q0UWF6    ), 
PXR1_PICGU  (A5DRH5    ), PXR1_SCHPO  (Q9URX9    ), PXR1_SCLS1  (A7EFS3    ), 
PXR1_VANPO  (A7TG30    ), PXR1_YARLI  (Q6C1L3    ), PXR1_YEAS7  (A6ZUT6    ), 
PXR1_YEAST  (P53335    ), RBM10_HUMAN (P98175    ), RBM10_MOUSE (Q99KG3    ), 
RBM10_RAT   (P70501    ), RBM5A_XENLA (A0JMV4    ), RBM5B_XENLA (Q6DDU9    ), 
RBM5_BOVIN  (Q1RMU5    ), RBM5_HUMAN  (P52756    ), RBM5_MOUSE  (Q91YE7    ), 
RBM5_RAT    (B2GV05    ), RBM5_XENTR  (A4IGK4    ), RBM6_HUMAN  (P78332    ), 
SON_HUMAN   (P18583    ), SON_MOUSE   (Q9QX47    ), SP382_YEAST (Q06411    ), 
SPF45_HUMAN (Q96I25    ), SPF45_MOUSE (Q8JZX4    ), SPP2_ASPFU  (Q4WP02    ), 
SPP2_EMENI  (Q5B4R9    ), SPP2_USTMA  (Q4P9X4    ), SQS1_ASHGO  (Q75E62    ), 
SQS1_CANAL  (Q59UG4    ), SQS1_CANGA  (Q6FP19    ), SQS1_DEBHA  (Q6BYP9    ), 
SQS1_KLULA  (Q6CQ59    ), SQS1_LODEL  (A5DSB5    ), SQS1_PICGU  (A5DEF8    ), 
SQS1_PODAS  (Q875B6    ), SQS1_VANPO  (A7TQN2    ), SQS1_YARLI  (Q6C233    ), 
SQS1_YEAS7  (A6ZRL6    ), SQS1_YEAST  (P53866    ), STIP1_ARATH (Q9SHG6    ), 
STIP2_ARATH (Q9SLC6    ), SUA_ARATH   (F4JCU0    ), SUGP1_ARATH (Q94C11    ), 
SUGP1_HUMAN (Q8IWZ8    ), SUGP1_MOUSE (Q8CH02    ), SUGP1_RAT   (Q68FU8    ), 
SUGP2_HUMAN (Q8IX01    ), SUGP2_MOUSE (Q8CH09    ), TFP11_BOVIN (Q29RR5    ), 
TFP11_CAEEL (Q17784    ), TFP11_CANLF (A1XD97    ), TFP11_CHICK (Q5ZII9    ), 
TFP11_DANRE (Q6DI35    ), TFP11_DICDI (A1XDC0    ), TFP11_DROME (Q9Y103    ), 
TFP11_HUMAN (Q9UBB9    ), TFP11_MACFA (A1XD95    ), TFP11_MACMU (A1XD94    ), 
TFP11_MONDO (A4UMC6    ), TFP11_MOUSE (Q9ERA6    ), TFP11_PANTR (A1XD93    ), 
TFP11_PIG   (Q06AK6    ), TFP11_PONAB (Q5R5K8    ), TFP11_RABIT (A4UMC5    ), 
TFP11_RAT   (Q5U2Y6    ), TFP11_XENLA (Q66J74    ), TFP11_XENTR (Q0IIX9    ), 
TGHH_ORYSI  (B8B2G4    ), TGHH_ORYSJ  (Q67VW6    ), VP113_HUMAN (P63121    ), 
VPK04_HUMAN (P63124    ), VPK10_HUMAN (P10265    ), VPK18_HUMAN (P63123    ), 
VPK19_HUMAN (P63120    ), VPK21_HUMAN (P63119    ), VPK24_HUMAN (P63129    ), 
VPK25_HUMAN (P63125    ), VPK6_HUMAN  (Q9Y6I0    ), VPK7_HUMAN  (P63131    ), 
VPK8_HUMAN  (P63122    ), VPK9_HUMAN  (P63127    ), VPRT_JSRV   (P31625    ), 
VPRT_MPMV   (P07570    ), VPRT_SMRVH  (P21407    ), VPRT_SRV1   (P04024    ), 
VPRT_SRV2   (P51518    ), Y5282_DICDI (Q54XG0    ), YAB4_SCHPO  (Q09806    ), 
YDMD_SCHPO  (P87143    ), YG0G_SCHPO  (O94728    ), YKR3_SCHPO  (Q9UTK6    ), 
YL271_YEAST (Q06152    ), YND2_SCHPO  (O74363    ), YQ7D_SCHPO  (O94585    ), 
ZGPAT_AEDAE (Q17CQ8    ), ZGPAT_ANOGA (Q7PYU6    ), ZGPAT_BOVIN (Q17QX2    ), 
ZGPAT_DANRE (Q7SXW2    ), ZGPAT_DROAN (B3MPC0    ), ZGPAT_DROER (B3N8L3    ), 
ZGPAT_DROGR (B4JCG4    ), ZGPAT_DROME (Q9VL59    ), ZGPAT_DROMO (B4KH32    ), 
ZGPAT_DROPE (B4G7U3    ), ZGPAT_DROPS (Q29NF3    ), ZGPAT_DROSE (B4HWD7    ), 
ZGPAT_DROSI (B4Q8A7    ), ZGPAT_DROVI (B4M9F7    ), ZGPAT_DROYA (B4NYQ2    ), 
ZGPAT_HUMAN (Q8N5A5    ), ZGPAT_MOUSE (Q8VDM1    ), ZGPAT_NEMVE (A7SBN6    ), 
ZGPAT_RAT   (Q5PPF5    ), ZGPAT_SALSA (C0HAV3    ), ZGPAT_SHEEP (C5IJB0    ), 
ZGPAT_XENLA (Q5U4Z3    ), ZGPAT_XENTR (Q28H71    )
» more

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

SPP2_YEAST  (Q02521    ), TGH_ARATH   (Q8GXN9    )

		

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