PROSITE entry PS50199
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General information about the entry
| Entry name [info] | ZF_RANBP2_2 |
| Accession [info] | PS50199 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2001 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50199 |
| Associated ProRule [info] | PRU00322 |
Name and characterization of the entry
| Description [info] | Zinc finger RanBP2 type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=30; /DISJOINT: DEFINITION=PROTECT; N1=4; N2=27; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.1729000; R2=0.0112922; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=941.1036377; R2=2.0848954; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=605; H_SCORE=2202; N_SCORE=8.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=472; H_SCORE=1925; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='R'; M= -9, -6,-27, -5, 2,-23,-18, -9,-21, 20,-20, -9, -3, -7, 4, 22, -4, -6,-15,-24,-12, 1; /M: SY='E'; M= 2, -2,-24, 0, 11,-17,-17,-12,-13, -3,-15,-12, -5, -2, -2,-10, 1, -5,-11,-26,-14, 4; /M: SY='G'; M= -4, 4,-28, 4, -6,-29, 39,-12,-35, -8,-29,-20, 9,-17,-10,-11, 2,-14,-28,-26,-25, -8; /I: I=-8; MI=-5; MD=-10; IM=-5; DM=-10; /M: SY='D'; M=-11, 9,-27, 15, 11,-21,-15, 0,-25, 1,-22,-16, 2, -9, 8, -4, 1, -5,-23,-18, -5, 9; /M: SY='W'; M=-20,-40,-50,-40,-30, 10,-20,-30,-20,-20,-20,-20,-40,-30,-20,-20,-40,-30,-30,150, 30,-20; /M: SY='E'; M= -9, 8,-26, 11, 12,-26,-17, 2,-21, 4,-18,-11, 4, -9, 10, -1, -1, -4,-19,-29,-12, 11; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /I: MI=-5; MD=-10; IM=-5; II=-9; DM=-10; I=0,0,-30,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0; /M: SY='S'; M= -4, 6,-22, 5, 4,-23,-11, -5,-22, -1,-26,-17, 9, 9, -1, -6, 11, 7,-19,-34,-18, 0; /M: SY='S'; M= 1, -8,-18, -9, -5,-17,-10,-12,-11, -3,-13, -8, -4,-15, -5, -6, 8, 7, -2,-29,-13, -5; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='T'; M= -5, -6, -7,-11,-12,-10, -3,-13,-14,-14, -8, -9, 0,-21,-12,-13, 1, 3,-11,-26,-11,-12; /M: SY='V'; M= -7,-13,-18,-17,-15, 4,-24,-14, 8,-14, 6, 2, -9,-25,-18,-12,-10, -2, 12,-22, -1,-16; /M: SY='Q'; M= -8, -6,-23, -8, -3,-16,-19, -4, -9, 4,-11, 3, -3,-16, 8, 6, -2, -1, -7,-24, -8, 2; /M: SY='N'; M=-10, 37,-13, 17, -2,-20, -2, 8,-21, -2,-29,-20, 56,-21, -2, -2, 9, -1,-29,-41,-21, -2; /M: SY='F'; M= -8,-10,-20,-12, 2, 3,-20,-12,-18, -1,-15,-12, -8, -7, -8, -4, -6, -7,-15,-12, -2, -3; /M: SY='A'; M= 22,-11,-17,-14, -6,-20, -7,-17,-13, -7,-15,-11, -9, 4, -6,-12, 7, 1, -7,-25,-19, -7; /M: SY='E'; M= -5, -1,-23, -2, 3,-15,-15, -4,-20, 0,-16,-12, -1,-14, -1, 3, 3, 3,-15,-17, -8, 0; /M: SY='R'; M= 7, -2,-20, -2, 1,-22,-10,-10,-21, 4,-20,-14, 0, -7, 0, 9, 7, -1,-13,-27,-17, -1; /M: SY='T'; M= -6, -6,-20,-11, -8,-10,-19,-12, -3, -6, -6, -3, -1,-14, -7, -4, 1, 6, -2,-27, -8, -9; /M: SY='K'; M= -6, -4,-26, -3, 10,-22,-19, 0,-21, 20,-20, -9, -3,-13, 5, 15, -5, -8,-13,-22, -7, 6; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='V'; M= -5,-10,-18,-17,-18, 8,-21,-17, 7,-16, 0, -1, -4,-23,-20,-15, -7, -4, 10,-22, -4,-19; /M: SY='A'; M= 9, -9,-12,-14, -7,-19,-13,-11,-12, 1,-14, -7, -4,-16, 0, 6, 3, -2, -5,-25,-15, -5; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='G'; M= -7, -2,-29, -3, 2,-25, 8, -8,-27, 0,-24,-13, 2,-15, 8, -2, -1,-10,-26, -8,-14, 5; /M: SY='S'; M= 9, 2,-13, -7, -7,-14, -4,-12,-15, -8,-17,-13, 8,-14, -8,-10, 13, 13, -9,-28,-14, -8; /M: SY='P'; M= -3,-12,-27, -7, 0,-21,-17,-12,-14,-10,-15,-12,-11, 28, -7,-12, -1, -2,-15,-30,-19, -6; /M: SY='K'; M=-10, -1,-28, -2, 4,-25,-16, -7,-27, 34,-25,-11, 3,-14, 7, 34, -7, -9,-18,-22,-12, 4; /M: SY='P'; M= -8, -8,-29, -4, 1,-21,-10,-13,-21, -1,-20,-13, -7, 17, -4, -7, -3, -5,-20,-25,-16, -3; /M: SY='D'; M= -3, 3,-24, 4, 1,-24, -2,-11,-20, -6,-19,-14, 1, -3, -3,-10, 3, -1,-16,-29,-19, -2; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 174 in 103 different sequences |
| Number of true positive hits | 174 in 103 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 12 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 93.55 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 8 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | K_Hofmann |
| Feature key [info] | ZN_FING |
| Feature description [info] | RanBP2-type |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
103 sequences
ARI8_ARATH (Q8W468), CAN15_HUMAN (O75808), CAN15_MOUSE (Q9JLG8), CAND_DROME (P27398), CAZ_DROME (Q27294), DRI1_SCHPO (O13801), DRI1_YEAST (P32770), EWS_HUMAN (Q01844), EWS_MOUSE (Q61545), FUS_BOVIN (Q28009), FUS_HUMAN (P35637), FUS_MOUSE (P56959), HOIL1_DANRE (A9JTG5), HOIL1_DICLA (E6ZIJ1), HOIL1_HUMAN (Q9BYM8), HOIL1_MOUSE (Q9WUB0), HOIL1_RAT (Q62921), MDM2_CANLF (P56950), MDM2_DANRE (O42354), MDM2_FELCA (Q7YRZ8), MDM2_HORSE (P56951), MDM2_HUMAN (Q00987), MDM2_MESAU (Q60524), MDM2_MOUSE (P23804), MDM2_XENLA (P56273), MDM4_BOVIN (Q2HJ21), MDM4_DANRE (Q7ZUW7), MDM4_HUMAN (O15151), MDM4_MOUSE (O35618), MDM4_RAT(Q5XIN1), MDM4_XENLA (Q7ZYI3), NEIL3_BOVIN (Q3MHN7), NEIL3_HUMAN (Q8TAT5), NEIL3_MOUSE (Q8K203), NEIL3_XENLA (A0A1L8HU22), NPL41_CAEEL (H2KYU6), NPL42_CAEEL (Q95QZ9), NPL4_DROME (Q9VBP9), NPL4_HUMAN (Q8TAT6), NPL4_MOUSE (P60670), NPL4_RAT(Q9ES54), NU153_DROME (Q9VXE6), NU153_HUMAN (P49790), NU153_RAT (P49791), NU153_XENLA (Q640Z6), RBL14_ARATH (Q8RXW0), RBM10_HUMAN (P98175), RBM10_MOUSE (Q99KG3), RBM10_RAT (P70501), RBM5A_XENLA (A0JMV4), RBM5B_XENLA (Q6DDU9), RBM5_BOVIN (Q1RMU5), RBM5_HUMAN (P52756), RBM5_MOUSE (Q91YE7), RBM5_RAT(B2GV05), RBM5_XENTR (A4IGK4), RBP2_DROME (A0A0B4K7J2), RBP2_HUMAN (P49792), RBP2_MOUSE (Q9ERU9), RBP2_PANTR (H2QII6), RBP56_HUMAN (Q92804), RNF31_HUMAN (Q96EP0), RNF31_MOUSE (Q924T7), RYBPA_DANRE (Q7SYB3), RYBPB_DANRE (Q5EG55), RYBP_HUMAN (Q8N488), RYBP_MOUSE (Q8CCI5), SHRPN_BOVIN (E1BDF2), SHRPN_HUMAN (Q9H0F6), SHRPN_MOUSE (Q91WA6), SHRPN_RAT (Q9EQL9), SUA_ARATH (F4JCU0), TA15B_ARATH (Q94KD0), TAB2_DANRE (Q5RFW2), TAB2_HUMAN (Q9NYJ8), TAB2_MOUSE (Q99K90), TAB2_RAT(Q5U303), TAB3_HUMAN (Q8N5C8), TAB3_MOUSE (Q571K4), TAB3_XENLA (Q7ZXH3), TAF15_ARATH (Q9AST1), TRBID_DROME (Q9VH90), TX13A_HUMAN (Q9BXU3), VAR3_ARATH (Q8S9K3), YAF2_HUMAN (Q8IY57), YAF2_MOUSE (Q99LW6), YDMD_SCHPO (P87143), ZRAB2_CHICK (Q5ZLX5), ZRAB2_HUMAN (O95218), ZRAB2_MOUSE (Q9R020), ZRAB2_PIG (Q19QU3), ZRAB2_PONAB (Q5R580), ZRAB2_RAT (O35986), ZRAB3_BOVIN (E1BB03), ZRAB3_HUMAN (Q5FWF4), ZRAB3_MOUSE (Q6NZP1), ZRAN1_BOVIN (A6QP16), ZRAN1_HUMAN (Q9UGI0), ZRAN1_MOUSE (Q7M760), ZRAN1_XENTR (B1H2Q2), ZRN1A_XENLA (Q5U595), ZRN1B_DANRE (A0JMQ9), ZRN1B_XENLA (Q6NUB7)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
12 sequences
ARI13_ARATH (Q9FFN9), ARI14_ARATH (Q9FFP1), ARI15_ARATH (Q84RQ8), ARI16_ARATH (Q9C5A4), HDA15_ARATH (Q8GXJ1), LUBEL_DROME (Q8IPJ3), TAMO_DROME (Q9W1A4), TX13C_HUMAN (A0A0J9YWL9), TX13D_HUMAN (A0A0J9YY54), VPS36_SCHPO (O43038), VPS36_YEAST (Q06696), YZR3_ARATH (Q8GZ43)» more |
| PDB [Detailed view] |
62 PDB
1N0Z; 1NJ3; 1Q5W; 2C6A; 2C6B; 2CR8; 2CRC; 2D9G; 2EBQ; 2EBR; 2EBV; 2GQE; 2K0C; 2K1P; 2LK0; 2LK1; 2MXV; 2WWZ; 2WX0; 2WX1; 3A9J; 3A9K; 3B08; 3B0A; 3CH5; 3G9Y; 3GJ3; 3GJ4; 3GJ5; 3GJ6; 3GJ7; 3GJ8; 4OWF; 4S1Z; 4XXB; 5AF6; 5YVG; 5YVH; 6G99; 7E62; 7MNP; 7MNQ; 7MNR; 7MNS; 7MNT; 7MNU; 7MNV; 7MO1; 7MO2; 7MO3; 7MO4; 7MO5; 7PCV; 7PDV; 7R5J; 7R5K; 7TV4; 7YUI; 8BGU; 8IM5; 8ONS; 8PP6 » more |