PROSITE entry PS50219
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General information about the entry
| Entry name [info] | CNH |
| Accession [info] | PS50219 |
| Entry type [info] | MATRIX |
| Date [info] |
01-SEP-2009 CREATED;
26-FEB-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50219 |
| Associated ProRule [info] | PRU00795 |
Name and characterization of the entry
| Description [info] | Citron homology (CNH) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=279; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=274; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6258330; R2=0.0039226; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=42619.5273438; R2=12.3632212; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=2390; H_SCORE=72168; N_SCORE=11.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=1243; H_SCORE=57987; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-16; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='P'; M= -25, -64, 34, 5, -38, -8, -6, -26, 2, -35, -53, 29, 61, -21, 1, 8, 8, -26, -69, -39; /M: SY='S'; M= 5, -34, -48, 11, -15, -6, 8, 5, -11, 14, -21, 13, -30, 6, -6, 23, -10, 4, -62, -6; /M: SY='K'; M= -36, -63, 10, 30, -59, -47, 36, -28, 40, -42, -33, 4, -15, 24, 30, 8, 15, -31, -65, -2; /M: SY='I'; M= -22, -61, -51, -67, -28, -73, -68, 84, -64, 3, -3, -63, -63, -61, -66, -57, -36, 44, -61, -2; /M: SY='N'; M= -31, -13, -31, 15, -14, -52, -4, -33, -13, -7, -47, 60, -37, -13, -2, 16, 57, -37, -68, -19; /M: SY='C'; M= 17, 120, -5, -54, -58, -51, -57, -47, -54, -48, -54, -31, -34, -54, -47, 46, -30, -33, -76, -29; /M: SY='V'; M= 26, -3, -46, -35, 9, -3, -59, 29, -44, 3, 25, -53, -38, -54, -59, 5, 3, 40, -63, -34; /M: SY='E'; M= 33, 34, 33, 38, -16, -38, -13, -24, -21, -12, -48, -21, -54, -4, -50, -2, 19, -10, -67, -25; /M: SY='Y'; M= 17, 8, -31, 4, -5, -31, -30, -3, -31, -19, -45, -46, 20, 12, -39, 32, 27, -5, -8, 33; /M: SY='W'; M= -41, 25, -38, -61, 54, -63, 11, -2, -56, 0, -8, -26, -67, -39, -34, -20, -32, -17, 111, 62; /I: I=-17; MD=-42; /M: SY='D'; M= -50, -18, 26, -12, -87, -43, -43, -30, -38, -69, -50, -8, -35, -27, -56, -13, -13, -23,-100, -58; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='D'; M= -16, -31, 40, 19, -65, 32, 14, -65, -5, -38, -55, 36, -18, 36, 9, 0, -16, -62, -69, -34; /M: SY='D'; M= -34, -40, 47, 6, -64, 0, -13, -51, 10, -55, -54, 42, -28, 43, 23, 11, -3, -23, -70, -25; /M: SY='N'; M= -46, -6, -33, -39, 32, -55, 24, -20, 18, -3, -19, 58, -27, -19, 15, -4, 0, -36, -11, 36; /M: SY='L'; M= -51, -34, -69, -47, -5, -73, -60, 42, -52, 64, -11, -49, -68, -59, -49, -51, -32, 32, -60, -30; /M: SY='Y'; M= -11, -61, -66, -63, 48, -67, -44, 11, -60, 42, -29, -46, -69, -57, -58, -56, -50, -6, -3, 84; /M: SY='V'; M= -13, -13, -70, -64, 15, -70, -63, 47, -49, 35, -4, -64, -66, -61, -63, -56, -26, 57, -60, -6; /M: SY='G'; M= 13, -61, -38, -59, -69, 92, -58, -72, -44, -70, -60, -39, -55, -53, -62, -10, -30, -53, -62, -64; /M: SY='T'; M= -6, 48, -19, -50, -11, -45, -54, -45, -49, 2, -44, -11, -53, -51, -55, 6, 88, -34, -69, -21; /M: SY='S'; M= -18, -29, 35, 38, -64, -34, -42, -51, -4, -63, -56, 45, -52, 19, 2, 47, 12, -58, -71, -28; /M: SY='D'; M= 11, -59, 41, 30, -47, -33, 13, -50, -13, -27, -32, 39, -53, 21, -45, 28, 13, -40, -69, -11; /M: SY='G'; M= -12, -19, -51, -61, -69, 94, -31, -75, -56, -72, -61, -17, -56, -53, -62, 4, -51, -68, -63, -64; /M: SY='V'; M= -30, -38, 21, 26, -37, -28, 7, 23, -14, 20, -18, -6, -58, -5, -21, -17, -3, 29, -67, -23; /M: SY='Y'; M= -55, -62, -68, -50, 46, -71, -49, 34, -61, 45, -16, -48, -69, -59, -60, -60, -50, 8, 27, 69; /M: SY='L'; M= -16, 15, -47, -48, 6, -66, -29, 31, -45, 51, 18, -35, -66, -24, -38, -22, -17, 13, -55, 27; /M: SY='H'; M= -7, 11, -55, -41, -33, -18, 74, 16, -21, 18, 13, -46, -60, -10, -8, 14, -4, 11, -20, -9; /I: I=-5; MD=-12; /M: SY='Y'; M= -60, 2, -63, -82, 45, -66, -36, -36, -77, -18, -21, -60, -59, -76, -76, -56, -43, -52, 5, 75; D=-5; /I: I=-5; MD=-12; /M: SY='V'; M= -41, -41, -52, -27, 4, -80, -1, -24, -13, -52, -66, -14, -51, -32, -29, -2, -10, 8, -84, -22; D=-5; /I: I=-5; MD=-12; /M: SY='C'; M= -61, 8, -79, -17, -31, -44, -46, 5, -61, -7, -63, -54, -62, -27, -12, 0, -44, -12, -88, -44; D=-5; /I: I=-5; MD=-12; /M: SY='F'; M= -65, -90, -15, -14, -6, -72, -47, -13, -29, -11, -43, -21, -28, -49, -36, -32, -23, -42, -87, -21; D=-5; /I: I=-5; MI=0; MD=-12; IM=0; DM=-12; /M: SY='D'; M= -20, -38, 52, 43, -50, -21, 5, -33, 8, -36, -55, 40, -38, 18, -10, 18, -15, -58, -72, -54; /M: SY='R'; M= -1, -29, -14, 8, -17, -11, -14, -3, -16, 24, -6, -12, -2, 1, 24, 6, -7, 2, -62, -14; /M: SY='N'; M= -15, -61, 31, -8, -63, 6, 20, -62, 8, -48, -54, 44, 16, 17, 0, 33, 10, -48, -19, -32; /I: I=-17; MD=-42; /M: SY='N'; M= -23, 0, 13, 2, -65, 12, -50, -32, -19, -42, -9, 41, 16, -12, 4, 13, 17, -30, -74, -39; D=-17; /I: I=-17; MD=-42; /M: SY='Y'; M= -24, -37, -36, -21, 28, -41, -32, -5, -23, 10, -15, -64, 3, -61, -51, -1, -16, -17, 5, 40; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='H'; M= -25, -71, 6, 4, -14, -31, 20, 0, -13, -7, 3, -20, 1, 4, -13, -17, -14, -13, -67, 19; D=-17; /I: I=-17; DM=-42; /M: SY='W'; M= -19, -37, 0, 7, -22, -49, 14, -1, -12, 20, -5, 9, 24, 14, 14, 5, -2, -22, 37, -34; /M: SY='R'; M= 0, -60, -15, -12, -18, -18, -5, -12, 13, -6, -44, 13, -6, 23, 32, 7, 18, 9, -66, -50; /M: SY='S'; M= -27, -16, -4, -2, -40, -2, -28, -12, 23, -1, 2, 13, -28, 5, 7, 34, 21, -19, -25, -23; /M: SY='W'; M= -20, -63, -42, -20, 34, -40, -7, 29, -10, 5, 12, -29, 32, 10, -10, 5, -18, -1, 47, -19; /M: SY='T'; M= -11, -15, 13, 17, -4, -40, 6, -24, 13, -4, -14, -15, -31, 19, 9, 13, 22, 10, -65, -21; /M: SY='K'; M= -35, -30, -31, -10, -60, -34, 36, -32, 51, -18, -16, 31, 7, 28, 39, -1, -20, -34, -66, -50; /M: SY='I'; M= -23, -9, -33, -35, 3, -12, -15, 39, -45, 27, -19, 1, -61, -8, -43, 17, 12, 20, -62, -21; /M: SY='F'; M= -4, -31, -28, -46, 38, -20, -4, 30, -34, 21, -35, 5, -3, -54, -57, 1, 20, 11, -58, -13; /M: SY='S'; M= -15, -1, 28, 11, -45, 16, 24, -58, -12, -42, -35, 21, 25, 23, -13, 28, 2, -15, -70, -54; /I: I=-15; MD=-39; /M: SY='K'; M= -44, -2, 13, -9, -27, -28, -13, -8, 37, -23, -31, 17, 10, 0, 25, 2, 6, -22, -70, -54; D=-15; /I: I=-15; MD=-39; /M: SY='K'; M= -21, -66, -37, -20, -54, -8, -5, -29, 51, -53, -54, 0, -26, 9, 43, 21, -8, -25, -69, -56; D=-15; /I: I=-15; MD=-39; /M: SY='P'; M= -15, -34, 1, -47, -52, -30, -34, -65, 19, -48, -23, 9, 63, -32, 15, 23, -11, -52, -73, -33; D=-15; /I: I=-15; MI=0; MD=-39; IM=0; DM=-39; /M: SY='V'; M= -27, 22, -48, -65, -9, -71, -70, 66, -51, -24, -29, -62, -41, -63, -65, -54, -18, 70, -67, -34; /M: SY='T'; M= -27, -58, 16, 5, -15, -55, -24, -22, 12, -29, -28, 15, -54, 35, 0, 17, 50, 4, -65, -6; /M: SY='Q'; M= -17, -31, -44, -3, -45, -45, -14, -62, 38, -50, -49, -18, -54, 93, 9, 9, -22, -61, 61, -28; /M: SY='I'; M= -51, -4, -72, -67, -21, -73, -63, 73, -64, 40, 53, -64, -64, -59, -64, -46, -30, 19, -62, -43; /M: SY='E'; M= 14, -17, -10, 34, -17, -27, 9, -3, 11, 12, -42, -32, -56, 18, -36, 3, 1, -10, -17, 13; /M: SY='V'; M= 5, 32, -45, -60, -40, -63, -34, 26, -59, 23, -19, -41, -33, -57, -61, -2, -14, 60, -64, 9; /M: SY='L'; M= -20, 1, -3, -59, -7, -66, -29, 43, -60, 51, 16, -16, -65, -40, -61, -14, -36, 25, -62, -28; /M: SY='P'; M= -10, -67, -19, 51, -68, -31, -48, -60, 11, -54, -55, -10, 77, 13, -14, 1, -4, -31, -67, -61; /I: I=-14; MD=-35; /M: SY='E'; M= -21, -66, 16, 49, -24, -23, 15, -34, 15, -35, -55, -17, -1, -1, 12, 18, 1, -50, -69, -35; D=-14; /I: I=-14; MI=0; MD=-35; IM=0; DM=-35; /M: SY='I'; M= -6, -63, -59, -4, 25, -53, 25, 33, -35, 23, -9, -7, -65, -25, -7, -42, -15, 6, -58, 19; D=-14; /I: I=-14; DM=-35; /M: SY='N'; M= -13, -61, 33, 18, -50, 27, -22, -66, 13, -66, -57, 59, -16, 28, -14, 15, -26, -63, -69, -38; /M: SY='L'; M= -42, -29, -43, -37, -30, -46, -53, 31, 32, 37, 7, -40, -42, -22, 31, -37, -5, 7, -14, -11; /M: SY='L'; M= 34, -17, -67, -60, 2, -61, -57, 6, -60, 60, 31, -63, -65, -56, -60, -51, -27, 16, -60, -43; /M: SY='L'; M= -37, 47, -71, -65, 24, -71, -59, 38, -63, 56, 39, -65, -68, -60, -63, -46, -37, 15, -58, -14; /M: SY='V'; M= 12, 17, -64, -38, -17, -62, -63, 39, -58, 1, 25, -58, -62, -57, -61, 2, -12, 62, -66, -28; /M: SY='L'; M= -53, -60, -68, -61, -33, -57, 18, 41, -58, 67, -12, -63, -67, -13, -4, -60, -49, 6, -61, -27; /M: SY='C'; M= 24, 83, -10, -31, -58, -8, -5, -21, -49, -55, -51, -42, -58, -6, -32, 52, 18, -6, -70, -23; /I: I=-20; MI=0; MD=-50; IM=0; DM=-50; /M: SY='D'; M= -15, -63, 71, 15, -69, 19, -11, -67, -21, -59, -60, 52, -9, 1, -36, -4, -5, -64, -76, -58; /M: SY='G'; M= -27, -39, -7, -2, -47, 37, 5, -65, 33, -54, -55, 23, 3, 3, 29, 25, -9, -52, 2, -54; /M: SY='T'; M= -16, -2, -25, -37, -15, -32, 15, -7, 12, -21, 5, -24, -56, 33, 11, 26, 35, 7, -15, 13; /M: SY='L'; M= -30, -57, -71, -64, -24, -55, -60, 25, -63, 67, 5, -67, -68, -59, -47, -60, -37, 41, -61, -30; /M: SY='Y'; M= -13, 47, -32, -32, 28, -60, 27, -17, -11, -10, -25, -26, -62, -21, 22, 1, 21, -11, -9, 60; /M: SY='Y'; M= 20, 6, -61, -47, 36, -49, -5, 4, -54, 15, 5, -30, -64, -10, -27, 4, -36, 33, -17, 38; /M: SY='Y'; M= -36, 19, -60, -60, 59, -42, 58, -4, -46, -4, -23, -42, -68, -54, -54, -32, -43, 0, -10, 85; /M: SY='D'; M= -29, -62, 39, 17, -60, -36, 36, -39, -10, -19, -3, 36, 27, -2, -3, 35, -5, -56, -71, -23; /M: SY='L'; M= -36, -29, -67, -48, -15, -36, -56, 29, -60, 67, 20, -47, -33, -56, -36, -17, -41, -5, 3, -1; /M: SY='P'; M= -23, -64, 33, -4, -23, -23, -5, -9, -9, -29, -50, 0, 63, -8, -12, 25, -7, 0, -67, -24; /M: SY='E'; M= 8, -16, 15, 44, -60, 2, 5, -46, -27, -18, -36, -4, -53, 15, -4, 30, 13, -14, 2, -53; /I: I=-2; MD=-5; /M: SY='L'; M= -56, -75, -64, -63, 1, -88, -75, 17, -44, 50, -10, -82, -57, -74, -77, -49, -65, -12, -75, -56; D=-2; /I: I=-2; MD=-5; /M: SY='D'; M= -54, -53, 3, -11, -34, -55, -13, -14, -48, -29, -9, -55, -60, -21, -34, -14, -15, -16, -93, -45; D=-2; /I: I=-2; MD=-5; /M: SY='P'; M= -34, -42, -29, -11, -95, -13, -77, -90, -22, -66, -83, -5, 24, -9, -57, -1, -25, -73, -97, -88; D=-2; /I: I=-2; MI=0; MD=-5; IM=0; DM=-5; /M: SY='R'; M= -49, -34, -24, -1, -48, -55, -11, -49, -15, -67, -41, -7, -25, -20, 11, 0, -8, -20, -92, -75; D=-2; /I: I=-2; DM=-5; /M: SY='H'; M= -37, -76, 2, -11, -53, 1, 21, -49, 17, -64, -42, -40, 15, -8, -19, 20, 1, -71, -82, -66; D=-2; /I: I=-2; DM=-5; /M: SY='F'; M= -31, -32, 1, -2, 37, -50, 0, -1, -15, 21, -39, -15, 21, -25, 7, 13, 15, -11, -58, -11; /M: SY='V'; M= 20, 15, -20, -2, -43, -22, -52, 9, -7, -16, -28, 15, -6, 9, -6, 20, -6, 27, -67, -25; /M: SY='P'; M= -13, -29, -25, -5, -14, -34, 15, 7, 12, 16, -29, -16, 48, 16, -17, 6, -15, -2, -62, -12; /M: SY='C'; M= -1, 27, -11, -2, 2, -5, -55, 16, 0, -5, -12, -48, 6, 9, -33, 14, 6, 13, 26, -33; /M: SY='T'; M= -14, -35, 3, -2, 26, -17, 9, 3, -7, -21, -25, 17, 5, 20, 2, 6, 26, -26, -59, 8; /M: SY='K'; M= -15, -60, -18, -5, -16, -14, 12, -20, 48, -22, -29, 19, -5, -11, 12, 17, 16, -18, 0, -21; /M: SY='I'; M= -27, -32, -63, -50, 4, -55, -59, 43, -15, 31, 27, -20, -35, -39, -11, -15, -8, 43, -63, -43; /M: SY='P'; M= -1, -62, 9, 11, -34, 25, 4, -39, 8, -37, -18, -13, 42, 13, -21, 13, 22, -33, -66, -38; /M: SY='D'; M= -19, -63, 39, 24, -27, 5, -10, -40, 39, -31, -32, 22, -18, -1, 11, 0, -16, -36, -64, -3; /M: SY='T'; M= -20, 25, -55, -36, 7, -37, 16, 23, -33, 0, 9, -10, -5, -37, -19, 20, 41, 20, -64, -18; /M: SY='K'; M= -40, -7, -1, -21, -47, -17, -12, -58, 67, -46, -18, 25, -44, -15, 43, -4, 7, -16, -66, -52; /M: SY='G'; M= -22, -33, 20, -22, -27, 59, 21, -25, -41, -26, -18, 38, 3, -20, -55, -4, -23, -35, 24, -34; /M: SY='C'; M= 20, 95, -59, -28, -50, -36, -26, 12, -31, -10, 1, -6, -64, -39, -38, -6, -9, 30, -14, -22; /M: SY='H'; M= -17, -59, -9, 7, -9, -14, 48, -5, -29, -16, -3, 16, -56, 8, -8, 13, 36, 12, -65, -1; /M: SY='W'; M= 7, -29, 31, -5, 18, -28, 11, -34, -15, 28, -8, -26, -59, -13, 4, -3, 4, -14, 35, -29; /M: SY='F'; M= -19, 37, -39, -63, 77, -66, -55, 15, -60, 13, -9, -22, -29, -42, -38, -36, -37, 12, 30, 27; /I: I=-24; MI=0; MD=-61; IM=0; DM=-61; /M: SY='C'; M= 24, 47, 10, -18, -14, 9, 11, -37, -4, -42, -51, 25, -38, -32, -18, 33, 2, -24, -64, 6; /M: SY='V'; M= -10, -31, -16, -17, -13, -24, -33, 24, -24, 15, -8, 1, -21, -52, -33, -9, -4, 46, 1, 18; /M: SY='S'; M= 9, -33, 30, -44, -31, 17, -3, -29, 1, -13, -4, 24, -28, -11, -24, 30, 0, 10, -69, -52; /M: SY='R'; M= -48, -64, -10, 28, -47, -32, -24, -29, 41, -23, -5, 5, -20, 25, 51, 4, 3, -28, -64, -25; /I: I=-9; MD=-24; /M: SY='N'; M= -25, 4, -6, -26, -5, -4, 30, 2, -25, -20, -1, 36, -10, 18, -44, 17, -21, -15, -66, 8; D=-9; /I: I=-9; MD=-24; /M: SY='D'; M= -28, -37, 33, 10, -51, -22, 8, -35, 26, -17, -34, 7, 28, -9, -1, 6, -17, -50, -26, -38; D=-9; /I: I=-9; MD=-24; /M: SY='E'; M= -21, -70, 21, 24, -33, 20, -34, -67, -11, -52, -61, 17, -2, 8, -1, 3, -10, -35, -71, -5; D=-9; /I: I=-9; MD=-24; /M: SY='N'; M= -25, -31, -7, -12, -42, 3, 5, -37, -2, -45, -26, 19, -39, -3, 4, 12, 11, -54, -79, -41; D=-9; /I: I=-9; MD=-24; /M: SY='T'; M= -30, -80, -30, -35, -35, 11, -11, -65, -47, -70, -72, -2, 6, -1, -4, 0, 19, -59, -85, -48; D=-9; /I: I=-9; MI=0; MD=-24; IM=0; DM=-24; /M: SY='C'; M= -22, 10, -3, -20, -24, -60, -24, -16, -45, -19, -6, -7, -21, -33, -19, -14, -5, -21, -85, -36; D=-9; /I: I=-9; DM=-24; /M: SY='P'; M= -29, -22, -42, -42, -33, -59, -42, -9, -17, 14, -16, -34, 18, -13, -25, -23, -10, 3, -72, 12; D=-9; /I: I=-9; DM=-24; /M: SY='Y'; M= -37, 4, -24, -14, 16, -44, 22, -5, 11, 9, -11, -9, -33, -21, 23, -2, 5, 12, -54, 42; /M: SY='L'; M= -11, -31, -65, -61, 25, -56, -58, 36, -37, 46, 15, -26, -48, -57, -44, -26, 4, 28, -58, -25; /M: SY='C'; M= 30, 76, -43, -43, 17, -49, -55, 4, -56, 14, 27, -43, -34, -31, -59, 4, -21, 10, -59, 17; /M: SY='V'; M= 19, 14, -32, -35, -19, -7, -58, 26, -40, -10, -10, -40, -60, -10, -57, 5, 1, 51, -62, 10; /M: SY='A'; M= 53, -56, -26, -7, -22, 20, -32, -15, -5, -9, -28, -35, -20, -20, -40, 14, -11, -2, -62, -19; /M: SY='T'; M= -13, -33, -20, -37, -35, -34, -8, 7, 7, 14, -15, -17, -29, -22, 24, 13, 40, 21, -66, -32; /M: SY='K'; M= -31, -65, 16, -7, -65, -10, -6, -52, 64, -55, -54, 27, 26, 14, 30, 2, -44, -52, -65, -38; /M: SY='K'; M= -27, -32, -5, -8, -12, -6, -28, -50, 52, -61, -35, 44, -39, -4, 37, 10, 15, -48, -14, -36; /M: SY='K'; M= -34, -62, -34, -13, -49, -17, -9, -53, 65, -46, -30, -6, -54, 17, 42, 29, 6, -48, -15, -23; /M: SY='I'; M= -42, -28, -41, -62, -38, -47, -63, 63, -30, 36, 13, -60, -45, -30, -61, -25, -12, 41, -64, -46; /M: SY='M'; M= -35, -16, -31, -21, 1, -29, 28, 10, 4, 17, 28, -49, -60, 17, 17, -3, 1, 22, -60, 8; /M: SY='I'; M= -29, -7, -66, -34, -14, -40, -61, 56, -49, 45, -5, -44, -64, -57, -36, -34, -16, 34, -61, -20; /M: SY='Y'; M= -32, -31, -65, -62, 58, -54, -18, 15, -44, 22, 20, -60, -7, -57, -34, -20, -28, 20, -13, 61; /M: SY='Q'; M= -22, -62, -12, 39, -45, -40, 0, -48, 27, -36, -32, -16, -52, 54, 20, 7, 34, -18, -64, -15; /M: SY='W'; M= -11, -64, -51, -49, 33, -65, -24, 44, -39, 12, -20, -43, 5, -57, -39, -39, -22, 6, 99, 33; /M: SY='D'; M= -15, -61, 26, 17, -21, 9, -3, -17, 14, -11, -47, 14, -29, 3, -8, 5, 20, -23, -61, 19; /M: SY='N'; M= -3, -33, 26, 30, -7, -3, 16, -28, 1, -25, -50, 38, -6, 12, 9, 7, -27, -19, -67, -51; /I: I=-12; MI=0; MD=-30; IM=0; DM=-30; /M: SY='D'; M= -29, -32, 38, -13, -77, 17, -6, -62, 14, -76, -44, 30, -52, -26, 14, -20, -15, -62, -30, -66; D=-12; /I: I=-12; DM=-30; /M: SY='P'; M= -9, -61, -2, 19, -62, -4, -24, -31, 17, -34, -11, 32, 42, 8, -15, 23, 13, -14, -69, -56; /M: SY='F'; M= -19, -60, -23, -36, 48, -54, -14, 22, -17, 21, 30, -30, -10, -7, 7, -30, -12, 16, -53, 11; /M: SY='N'; M= -39, -18, 16, 5, -21, -12, -16, -20, 21, -18, -26, 24, -5, 17, 21, 14, 15, 4, -67, -36; /M: SY='K'; M= -7, -14, -21, 24, -22, -16, 8, -18, 30, -9, -15, -13, -11, -8, 23, 14, 5, -14, -2, -2; /M: SY='F'; M= -22, -59, -24, -29, 79, -53, 28, 0, -45, -4, -22, -31, -47, 6, -17, -9, -8, 14, -46, 14; /I: I=-10; MI=0; MD=-25; IM=0; DM=-25; /M: SY='K'; M= -23, 4, -25, -22, -42, -40, 8, -11, 51, -29, 18, 10, -34, 25, 51, -14, -21, -17, -63, -14; /M: SY='E'; M= -26, -62, 24, 44, -14, -33, -3, 3, 19, 0, -7, 14, 17, -39, -21, -12, 4, -15, -66, -29; /M: SY='I'; M= -35, -35, -39, -59, 27, -66, 8, 48, -28, 18, 8, -41, -64, -27, -9, -5, -30, 21, -11, 47; /M: SY='K'; M= 0, -17, 12, 16, -64, -33, -23, -42, 52, -52, -29, 14, 2, 4, 37, 11, -3, -47, -67, -54; /I: I=-20; MD=-50; /M: SY='E'; M= -44, -74, 17, 50, -3, -46, -32, -45, 11, -50, -35, -38, -12, -14, 10, -7, -22, -47, -68, 9; D=-20; /I: I=-20; MD=-50; /M: SY='F'; M= -28, -44, -54, -71, 49, -42, -38, 36, -46, 1, -31, -51, 8, -35, -70, -35, -45, -1, -59, 10; D=-20; /I: I=-20; MI=0; MD=-50; IM=0; DM=-50; /M: SY='Y'; M= -24, -10, -2, -22, -16, -13, 16, -31, -8, -25, -11, -3, -14, 6, -33, 9, -4, -15, -65, 35; D=-20; /I: I=-20; DM=-50; /M: SY='L'; M= -19, 26, -66, -46, 23, -33, -59, 30, -59, 39, 12, -46, -65, -39, -46, -28, 5, 37, -1, -12; /M: SY='P'; M= 5, -7, -10, -24, -61, -22, -13, -16, -1, -23, -18, -7, 83, 3, -40, 17, -19, -16, -67, -41; /M: SY='D'; M= -7, 8, 56, 26, -48, 11, -28, -40, -7, -30, -54, 8, -22, -19, -21, 22, 13, -29, -70, -25; /M: SY='P'; M= 6, -20, 2, 13, -26, 0, -26, -16, 3, -20, -27, -4, 38, -11, 8, 24, 2, -14, -64, -14; /M: SY='P'; M= 13, 56, -59, -41, -29, -40, -61, 18, -54, -8, -41, -43, 60, -36, -45, 8, -1, 36, -68, -55; /M: SY='Q'; M= -29, -32, -49, -35, -3, -57, 0, -6, 22, -7, -19, 10, -3, 34, 31, 14, 19, -10, -21, 25; /M: SY='S'; M= 10, 39, -15, -38, -30, 2, -18, -43, -11, -36, -7, 13, -37, -7, 11, 50, 31, -26, -25, -36; /M: SY='I'; M= -37, -59, -23, -49, 12, -29, -20, 52, -19, 39, 35, -32, -64, -56, -59, -30, -46, 31, -60, -30; /I: I=-8; MD=-19; /M: SY='H'; M= 14, 8, -12, 5, -32, -23, 36, -20, -39, -24, -35, -15, -45, -8, -1, 22, 12, -6, -73, -26; D=-8; /I: I=-8; MD=-19; /M: SY='W'; M= -24, -18, -75, -69, 47, -41, -67, -3, -31, -1, -18, -25, -74, -64, -3, -34, -15, -20, 101, 2; D=-8; /I: I=-8; MD=-19; /M: SY='F'; M= -40, 27, -44, -70, 40, -75, -39, -11, -68, 15, -8, -29, -28, -45, -54, -14, -2, 9, -26, 14; D=-8; /I: I=-8; MD=-19; /M: SY='N'; M= -14, -81, 14, -32, -87, 5, -41, -81, -66, -86, -79, 33, -16, -65, -32, 10, -30, -32, -95, -81; D=-8; /I: I=-8; MI=0; MD=-19; IM=0; DM=-19; /M: SY='D'; M= -77, -93, 16, -31, -34, -25, -28, -86, 15, -59, -78, -66, -10, -2, 11, -55, -47, -55, -87, -13; D=-8; /I: I=-8; DM=-19; /M: SY='N'; M= -21, -61, 41, -1, -59, 10, 7, -42, 2, -30, -53, 43, 27, -29, -4, 11, 24, -57, -68, -2; /M: SY='S'; M= -14, -16, -35, -22, 3, -35, 1, -1, 26, -17, 25, 1, -56, 10, -1, 48, 9, -46, 20, 5; /M: SY='I'; M= -7, -26, -68, -41, 28, -45, -37, 60, -62, 37, -14, -62, -32, -43, -63, -32, -36, 30, -58, -40; /M: SY='C'; M= 12, 110, -36, -62, 11, -41, -62, 21, -61, 3, 3, -56, -68, -45, -64, -21, -46, 14, -27, -20; /M: SY='V'; M= -14, 6, -67, -48, 0, -57, -39, 36, -61, 19, 0, -47, -46, -60, -62, -53, -13, 66, -19, 12; /I: I=-28; MI=0; MD=-71; IM=0; DM=-71; /M: SY='G'; M= 44, 14, -51, -34, -33, 60, 26, -48, -42, -46, -34, -33, -56, -48, -45, 21, -10, -19, -65, -55; /M: SY='C'; M= -33, 43, 13, -39, 17, -32, 5, -12, -28, 6, -14, 8, -44, -50, -33, 24, 39, 10, -62, 10; /I: I=-30; MD=-77; /M: SY='S'; M= 3, -32, -5, -7, -61, -4, 7, -45, 23, -30, -51, 17, -1, 14, 26, 37, -3, -17, -68, -38; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='K'; M= -47, -62, 11, -7, -62, -22, 20, -42, 55, -37, -52, 51, -12, -13, 27, 19, -17, -34, -68, -38; /M: SY='G'; M= -26, -34, 18, 27, -32, 51, -5, -49, -5, -41, -16, 20, -38, 2, -21, 19, 3, -59, -20, -26; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='Y'; M= -41, -63, -64, -64, 78, -54, -39, 0, -58, -13, -36, -35, -70, -58, -56, -30, -42, -36, 1, 98; /M: SY='E'; M= -6, 15, 20, 37, 5, -31, 34, -20, -23, -11, -23, -9, -30, -13, -27, 16, -25, 6, -59, 29; /M: SY='L'; M= -24, -28, -65, -33, -1, -55, -58, 43, -44, 43, 29, -61, -47, -39, -26, -19, -15, 35, -59, -3; /M: SY='I'; M= -43, -17, -68, -63, 11, -70, -33, 46, -61, 41, 33, -34, -37, -39, -61, -38, -24, 41, -56, 20; /M: SY='D'; M= -40, -17, 72, 11, -68, -32, -23, -67, -6, -68, -61, 61, -7, -28, 2, 26, -6, -63, -78, -57; /M: SY='L'; M= -3, -7, -21, -14, 6, -54, -29, 24, -47, 51, 22, -46, -25, -55, -59, -53, -10, 25, -60, -18; /M: SY='D'; M= -6, -15, 47, 30, -12, -29, -28, -58, 11, -44, -54, 26, -18, 20, -18, 27, 7, -26, -21, -39; /I: I=-14; MI=0; MD=-35; IM=0; DM=-35; /M: SY='D'; M= -18, -63, 33, 3, -50, -10, 12, -63, -1, -65, -58, 33, 9, 8, -2, 23, 31, -35, -74, -41; D=-14; /I: I=-14; DM=-35; /M: SY='G'; M= -2, -63, -49, 0, 9, 26, -4, -22, -4, -12, -4, 23, -7, 17, -6, -5, 5, -26, -28, -15; D=-14; /I: I=-14; DM=-35; /M: SY='Q'; M= -8, -60, 12, 9, -46, -14, 9, -39, -12, -6, -28, 18, -6, 43, 11, 22, 18, -4, -22, -51; /M: SY='T'; M= -1, -33, -23, -18, -29, -48, -17, 3, 27, 6, 27, -22, -11, -21, -19, 5, 39, 18, -64, -11; /M: SY='P'; M= -26, -32, -39, -1, -19, -22, -3, 32, -19, -24, -25, -16, 39, 31, -15, 29, 25, -9, -64, -26; /M: SY='P'; M= -24, 5, 30, 30, -65, -31, -28, -58, 10, -46, -55, 12, 60, -2, -23, 33, -13, -16, -71, -58; /M: SY='L'; M= -39, -59, -53, -41, 35, -70, -57, 18, -62, 66, -10, -66, -15, -39, -46, -47, -40, 2, 38, -16; /M: SY='F'; M= -22, -25, -63, -40, 70, -65, 9, -16, -48, 38, 19, -15, 9, -58, -58, -29, -30, -3, -45, 29; /M: SY='P'; M= -29, -65, 25, 7, -61, -18, 32, -40, -13, -28, -32, 36, 63, 13, 2, 8, -5, -41, -68, -15; /I: I=-2; MD=-6; /M: SY='P'; M= -15, -63, -3, -20, -12, -22, -18, 13, -36, 6, -5, -15, 23, -14, -36, -3, 19, 17, -63, 18; D=-2; /I: I=-2; MD=-6; /M: SY='S'; M= -9, -69, 19, 9, -68, -24, -10, -34, -4, -46, -36, -3, -11, -14, -55, 47, -16, -63, 17, -23; D=-2; /I: I=-2; MD=-6; /M: SY='D'; M= -29, -35, 44, -1, -55, -18, -9, -73, -28, -40, -24, 11, -4, -8, -62, 22, -19, -54, -87, -68; D=-2; /I: I=-2; MD=-6; /M: SY='T'; M= -30, -37, -52, -30, -12, -26, -43, -37, -35, -21, -27, -16, -4, -21, -24, 14, 22, -54, -81, -27; D=-2; /I: I=-2; MD=-6; /M: SY='S'; M= -47, -35, 17, -34, -60, -29, -72, -66, -19, -53, -51, -13, -13, -45, -55, 32, -12, -63, -95, -79; D=-2; /I: I=-2; MD=-6; /M: SY='L'; M= -39, -87, -6, -33, -57, -54, -23, -32, -33, 2, -16, -15, -29, -12, -58, -13, -46, -32, -89, -19; D=-2; /I: I=-2; MD=-6; /M: SY='D'; M= -8, -90, 8, -30, 2, -53, -24, -68, -50, -46, -78, -51, -38, -23, -8, -3, -73, -67, -26, -26; D=-2; /I: I=-2; MI=0; MD=-6; IM=0; DM=-6; /M: SY='P'; M= 6, -60, 5, 0, -13, -10, -17, -28, -14, 12, -3, 2, 23, -8, 13, 21, 14, -26, -63, -8; /M: SY='S'; M= -21, -6, 17, 6, -44, -2, -4, 1, 2, -9, -48, 18, -1, 0, -3, 43, 4, -38, -66, -13; /M: SY='E'; M= -13, -17, 6, 35, -22, -22, -23, -23, 5, -23, -28, 23, -30, 14, -1, 33, 14, -16, -24, -12; /M: SY='N'; M= -16, -33, -1, 1, -34, -4, 2, -41, 11, -15, -13, 39, 15, 12, -21, 32, 20, -13, -68, -35; /M: SY='C'; M= -3, 27, -42, -44, -1, -6, -55, 9, -33, 20, 6, -51, 10, -20, -45, 19, 22, 20, -61, 6; /M: SY='K'; M= -25, -63, -5, 23, -19, -24, -1, -40, 50, -46, -11, 21, 15, 25, 23, 10, -20, -38, -63, -22; /M: SY='P'; M= 10, -70, -42, -20, -66, -43, -55, -55, -24, -41, -53, -37, 108, -23, -57, -20, -35, -18, -65, -29; /M: SY='M'; M= -43, -36, -45, -57, -11, -31, 39, 44, -37, 37, 45, -30, -33, 1, -25, -45, -32, 17, 4, -1; /M: SY='I'; M= 18, 12, -27, -32, -24, 12, 19, 40, -17, -6, -15, -17, -59, -24, -31, 5, -6, 15, 16, -34; /M: SY='M'; M= 17, 21, -48, -35, -16, -48, -59, 28, -3, 5, 48, -38, -60, -53, -34, -39, 21, 44, -19, -47; /M: SY='F'; M= -26, -25, -33, -20, 44, -34, 9, 11, -22, 4, -39, -22, 18, -52, -10, 10, -5, 26, 23, 14; /M: SY='Q'; M= -29, -32, -3, -1, 23, -49, -14, -8, 9, 9, -14, -19, 30, 35, 33, -19, -1, -25, -58, -9; /M: SY='I'; M= -34, -10, 20, -27, -25, 4, -30, 32, -44, 26, -8, -21, 10, -34, -32, 5, 10, 14, -66, -35; /M: SY='D'; M= -9, -10, 46, 4, -65, 6, 3, -38, -10, -65, -57, 45, 32, -5, -37, 38, -4, -59, -72, -37; /M: SY='D'; M= -22, -63, 44, 42, -45, 14, -10, -64, 6, -56, -57, 36, -1, 12, -5, 11, -12, -34, -70, -38; /M: SY='E'; M= -36, -11, 44, 51, -21, -18, -12, -29, -1, -44, -23, 28, -6, 5, 2, 5, -5, -38, -20, -14; /I: I=-15; MD=-39; /M: SY='E'; M= -42, -69, 5, 41, 34, -1, -54, -48, 3, -2, -33, -19, -21, -6, -33, -14, -11, -48, -63, -13; D=-15; /I: I=-15; MI=0; MD=-39; IM=0; DM=-39; /M: SY='F'; M= -26, -58, -50, -47, 68, -46, -31, 10, -47, 14, 14, -43, -65, -58, -58, -7, 11, 23, -44, 46; /M: SY='L'; M= -5, -28, -38, -29, -13, -24, -55, 21, -47, 58, 27, -34, -64, -38, -20, -1, -24, -4, 1, -30; /M: SY='L'; M= -42, -13, -10, -21, -6, -56, -56, 11, -40, 58, 1, -32, -6, -41, -59, -20, -4, 26, -62, -19; /M: SY='C'; M= 4, 98, -9, -34, -53, 10, -59, -21, -38, -7, -26, -28, -32, -42, -34, 6, -6, 29, -72, -35; /M: SY='Y'; M= -30, -26, 13, -13, 47, -32, -23, -36, 10, -23, -12, -10, -33, -13, 1, 1, -2, -15, -42, 70; /M: SY='D'; M= -22, -62, 67, 16, -66, -14, -2, -62, -22, -47, -36, 42, 11, 11, -29, 24, 13, -44, -76, -56; /M: SY='N'; M= 0, -32, 17, 42, -47, 5, -11, -49, -20, -51, -31, 52, -53, 11, 0, 10, 21, -40, -17, -42; /M: SY='M'; M= -4, 33, -59, -28, 37, -13, 0, 14, -36, 10, 47, -19, -61, 14, -43, -20, 10, 12, -57, -1; /M: SY='G'; M= 38, 21, -54, -46, -48, 65, -58, -17, -44, -25, -50, -32, -57, -52, -59, 10, -10, 2, -64, -58; /M: SY='M'; M= -4, -12, -66, -61, 24, -54, -15, 41, -27, 9, 54, -58, -63, -43, -44, -27, -10, 50, -61, -29; /M: SY='F'; M= -28, -60, -50, -30, 85, -52, -29, 8, -15, -7, 5, -57, -43, -18, -19, -24, -22, -3, -38, 45; /M: SY='V'; M= -24, -57, -36, -35, -6, -67, -60, 37, -48, 4, 2, -41, -63, -9, -26, -27, -7, 68, -63, 8; /M: SY='N'; M= -35, -59, 66, -15, -64, -16, -20, -49, -14, -43, -57, 86, -56, -28, -35, -25, 17, -49, -80, -41; /M: SY='S'; M= -16, -21, -25, 0, -36, -16, -4, -12, 30, 12, 4, -7, -18, 1, 15, 32, 5, -14, -24, -34; /M: SY='H'; M= -22, -22, 33, 23, 15, -54, 35, -44, -10, -17, 0, 29, -57, 24, -20, 12, 1, -33, -17, 29; /I: I=-4; MI=0; MD=-9; IM=0; DM=-9; /M: SY='G'; M= -31, -13, -20, -27, -37, 90, -56, -71, -53, -57, -30, -21, -56, -33, -36, -6, -33, -49, -62, -61; /M: SY='W'; M= -29, 5, 45, 32, -36, -46, -27, -33, 21, -50, -9, 15, -54, 44, 23, -5, -6, -40, 45, -50; /M: SY='P'; M= -49, -31, -32, -7, -51, -32, -37, 32, 0, 3, 8, -30, 59, -21, 24, -11, -35, 24, -65, -37; /M: SY='T'; M= -14, 1, -20, -23, -29, -43, -52, -14, 10, -24, -47, -1, 1, -13, -28, 50, 52, 14, -69, -52; /M: SY='R'; M= -25, -66, -28, -5, -64, -13, 23, -62, 3, -52, -33, 10, 11, 26, 80, -1, -31, -27, -66, -51; /M: SY='W'; M= -19, -31, 2, -3, -60, 36, -5, -42, 18, -53, -36, 7, 35, -7, -6, 16, 19, -47, 40, -17; /I: I=-14; MD=-37; /M: SY='T'; M= -44, -21, 6, -24, -77, -29, -9, -45, 7, -38, -43, 3, -31, -5, 9, 5, 10, -37, -87, -69; D=-14; /I: I=-14; MI=0; MD=-37; IM=0; DM=-37; /M: SY='W'; M= -18, -21, -8, -28, 5, -51, -47, -20, -58, -40, -21, -15, -3, -70, -46, -10, -7, -30, 39, -19; D=-14; /I: I=-14; DM=-37; /M: SY='T'; M= -25, -14, 16, 19, -9, -45, -52, 18, -25, -31, -20, -22, 27, 2, -15, 14, 49, -29, 41, -23; /M: SY='I'; M= -44, -60, -68, -37, 26, -71, -61, 59, -61, 43, 1, -63, -14, -37, -38, -33, -25, 21, 0, -15; /M: SY='K'; M= -16, -24, 1, 20, -43, -24, 1, -3, 25, -15, 15, 3, 1, 24, -2, -9, 2, 15, 7, -32; /M: SY='W'; M= -21, -69, -45, -51, 66, -34, -65, -26, -32, 11, -24, -67, -32, -31, -59, -48, -59, -50, 137, -3; /M: SY='S'; M= -18, -61, 29, 32, -62, -10, 6, -46, -7, -21, -34, 23, 14, 8, -1, 37, 3, -16, -70, -54; /M: SY='F'; M= -16, -26, 8, 6, 37, 20, 4, -25, -5, -45, -50, -16, -28, -7, 21, 20, 21, -29, -58, -3; /M: SY='Y'; M= -3, -22, -38, -2, -16, -40, 16, -1, 8, -14, -2, -4, 32, -5, -6, -7, 13, -9, -52, 56; /M: SY='P'; M= 2, 30, -57, -31, -33, -39, -35, -1, -53, -18, -48, -58, 103, -54, -50, -33, -37, -10, -66, -61; /M: SY='Q'; M= -31, -61, 20, 21, -41, -40, 0, -10, 23, 5, 1, -5, -55, 35, -3, -6, 32, -3, -66, -26; /M: SY='S'; M= 23, -3, 3, -6, -21, 14, 15, -59, -25, -44, -34, 23, -41, 14, -31, 51, 5, -54, -64, 2; /M: SY='I'; M= 8, -34, -69, -50, 39, -67, -31, 51, -61, 16, 1, -62, -34, -45, -63, -45, -45, 51, -20, -25; /M: SY='A'; M= 42, 21, -22, -44, -37, -2, -17, 4, -32, -29, -16, -38, -58, -24, -34, 14, 13, 40, -66, -17; /M: SY='Y'; M= -38, 45, -49, -27, 40, -52, -28, 9, -45, 13, 17, -58, -66, -55, -30, -7, -30, 27, 20, 65; /M: SY='D'; M= -14, 30, 35, 7, -3, -58, 20, 0, -44, 5, -42, 2, -60, 12, 12, 5, -13, 13, -5, -6; /M: SY='Y'; M= -21, -30, 1, 27, 8, 3, 37, -57, -8, -33, -33, 14, -4, -3, -21, 29, -37, -48, 25, 51; /M: SY='P'; M= -41, -71, 11, -16, -29, 11, -12, -62, -39, -49, -56, 13, 100, -2, -43, -9, -28, -64, -67, -61; /M: SY='Y'; M= -38, 8, -28, -38, 42, -42, 33, -20, -51, -28, -12, -9, -66, -32, -28, 1, -22, -48, 12, 99; /M: SY='L'; M= -36, -58, -66, -40, -24, -59, -58, 42, -60, 50, -14, -36, -66, -20, -45, -34, -45, 47, -58, 19; /M: SY='F'; M= -29, -4, -24, -49, 46, -38, -57, 43, -49, 36, -8, -17, -66, -39, -48, -55, -11, 24, -53, 9; /M: SY='A'; M= 38, -9, -58, -56, -38, 19, -58, -3, -55, 20, -3, -31, -31, -52, -59, 13, 16, 28, -65, -52; /M: SY='F'; M= -4, -58, -36, -30, 64, -22, -56, 19, -58, 21, -9, -17, -34, -46, -46, -15, -6, 27, -50, -1; /M: SY='H'; M= -23, 2, 3, -5, -1, -1, 55, -32, -26, -5, -2, 23, -29, -33, -42, 22, 24, -7, 43, -3; /M: SY='P'; M= -4, -63, 37, 23, -11, -12, 6, -36, 3, -50, -53, -4, 46, -5, -24, 25, -11, -47, -60, 25; /M: SY='N'; M= -16, -61, 31, 12, -38, -8, 21, -63, -12, -63, -37, 58, 9, 25, 3, 32, -7, -51, -70, -23; /M: SY='F'; M= -9, 16, -52, -31, 30, 29, -7, -30, 26, -11, -30, -15, -16, -12, -13, 28, -22, -18, -55, 15; /I: I=-15; MI=0; MD=-39; IM=0; DM=-39; /M: SY='I'; M= -35, -31, -41, -36, -5, -72, -62, 62, -62, 33, 43, -63, -36, -59, -63, -58, -36, 44, -62, -27; /M: SY='E'; M= -27, -37, 23, 76, -62, -58, 11, -48, -23, -33, -52, 7, -50, 51, -30, -23, -23, -13, -66, -1; /M: SY='I'; M= -46, -59, -68, -55, -17, -9, -69, 69, -52, -10, 0, -44, -32, -61, -65, -44, -23, 62, -66, -46; /M: SY='W'; M= -31, -19, -56, -43, 17, -63, 51, -2, -18, -23, -13, -39, -46, -29, 61, -14, -40, -8, 63, 57; /M: SY='N'; M= -27, -59, 36, -2, -59, -22, 40, -56, -24, -8, -29, 48, -28, 11, -6, 48, -8, -33, -72, -35; /M: SY='I'; M= -6, -59, -52, -60, 12, -54, -59, 50, -21, 40, 0, -42, -5, -32, -47, -44, -15, 28, -14, -11; /M: SY='E'; M= -22, -62, 9, 35, -13, -26, 23, -18, 27, -10, -30, -8, -21, 7, 2, 13, -9, 3, -62, 6; /M: SY='N'; M= -28, -58, 39, -26, -45, -13, -21, -39, -27, -32, -52, 54, 18, -10, -22, 28, 47, -26, -72, -24; /M: SY='G'; M= -19, -18, 4, -39, -8, 54, -24, -46, -29, -5, -19, 7, -24, 29, -3, 17, -3, -40, -61, -12; /M: SY='E'; M= 4, -13, 33, 37, -42, -12, -16, -43, 1, -21, -30, 16, -23, 16, -12, 14, 4, -5, -67, -18; /M: SY='L'; M= -41, -17, -24, -12, -43, -40, 41, -6, -4, 44, 8, -5, -25, -9, -24, -14, 11, 12, 41, -43; /I: I=-15; MD=-39; /M: SY='V'; M= -29, -13, -36, -1, -26, -19, -59, 32, -5, -1, -3, -41, 7, -37, -17, -13, -1, 49, -66, -18; D=-15; /I: I=-15; MI=0; MD=-39; IM=0; DM=-39; /M: SY='Q'; M= -30, -31, -25, 7, -46, -46, 50, -61, 8, -57, -6, -37, -37, 100, 1, -4, -3, -49, -64, -46; /M: SY='T'; M= -19, -18, -5, 13, -8, -40, 14, 17, -16, -24, -24, -14, -55, 14, 1, 15, 42, 22, -66, -22; /M: SY='I'; M= -21, -61, -50, -36, -1, -69, -19, 70, -30, 19, 42, -60, -22, -56, -35, -32, -36, 22, -17, -10; /M: SY='N'; M= -22, -14, 15, 16, -59, -19, -4, -45, 8, -25, -28, 34, 29, 12, -9, 21, 27, -18, -19, -23; /M: SY='G'; M= -3, 1, 15, -33, 18, 34, 18, 13, -46, 26, 11, -7, -60, -32, -46, 0, -28, -21, -62, -44; /M: SY='P'; M= -19, -34, 14, 13, -66, -10, -8, -61, 34, -43, -53, 36, 44, 35, 10, 4, -14, -34, -68, -56; /M: SY='N'; M= -27, -33, 34, -3, -63, 18, -9, -19, 33, -61, -37, 37, -11, -6, 25, 17, -11, -41, -68, -25; /M: SY='I'; M= -5, 20, -23, -19, -16, -23, -6, 46, -43, 2, -6, -5, 17, -24, 5, 18, -36, 4, 6, -21; /M: SY='R'; M= -16, -15, -14, 0, -25, -30, -18, -10, 26, -12, -14, -11, -27, 26, 50, 5, 2, -4, -62, -10; /M: SY='F'; M= -31, 16, -17, -27, 33, -52, -7, -1, -29, 28, 29, 2, 14, -18, 0, -14, -2, -16, -6, 29; /M: SY='L'; M= -16, 0, -16, -31, -3, -11, -30, 37, -32, 40, -16, -30, -42, -37, -3, -10, 2, 7, -60, -10; /M: SY='S'; M= -13, 28, 4, -32, -20, -6, 12, 2, -27, 1, 0, 8, 10, -9, -42, 33, 14, 2, 13, -17; /M: SY='S'; M= -2, 12, 11, 13, -7, -15, -6, -17, -21, -11, -29, 1, -22, -14, -11, 45, 14, 0, -23, -36; /M: SY='G'; M= -13, 8, 11, -2, -23, 32, -30, -2, -5, -24, -25, 28, -14, -2, 1, 23, -4, -20, -66, -26; /M: SY='S'; M= -4, -61, 20, -1, -34, 5, -2, -39, 7, -33, -51, 11, 19, 16, 13, 33, 6, -16, -66, -14; /M: SY='D'; M= -17, -63, 49, -2, -26, 9, 26, -30, 0, -34, -18, 3, -2, -14, 20, 15, -2, -17, -4, -9; /M: SY='W'; M= -3, -9, 2, 14, -20, -2, -27, 11, 5, 2, -8, 10, -4, 3, 0, 6, -13, -11, 39, -34; /M: SY='H'; M= -35, 6, 21, -16, 16, -24, 23, 15, -27, -2, -15, 9, 4, 7, -21, 4, 0, 16, -61, 11; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 56 in 56 different sequences |
| Number of true positive hits | 56 in 56 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | CNH |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
56 sequences
CTRO_HUMAN (O14578), CTRO_MOUSE (P49025), CTRO_RAT(E9PSL7), GARL3_CHICK (Q5ZJY3), GARL3_DANRE (A5PF44), GARL3_HUMAN (Q5VVW2), GARL3_MOUSE (Q3V0G7), GEK_DROME (Q9W1B0), M4K1_HUMAN (Q92918), M4K1_MOUSE (P70218), M4K2_HUMAN (Q12851), M4K2_MOUSE (Q61161), M4K3_HUMAN (Q8IVH8), M4K3_MOUSE (Q99JP0), M4K3_RAT(Q924I2), M4K4_HUMAN (O95819), M4K4_MOUSE (P97820), M4K5_HUMAN (Q9Y4K4), M4K5_MOUSE (Q8BPM2), MIG15_CAEEL (Q23356), MINK1_HUMAN (Q8N4C8), MINK1_MOUSE (Q9JM52), MINK1_RAT (F1LP90), MRCKA_HUMAN (Q5VT25), MRCKA_MOUSE (Q3UU96), MRCKA_RAT (O54874), MRCKB_HUMAN (Q9Y5S2), MRCKB_MOUSE (Q7TT50), MRCKB_RAT (Q7TT49), MRCKG_HUMAN (Q6DT37), MRCKG_MOUSE (Q80UW5), MRCK_CAEEL (O01583), NRK_HUMAN (Q7Z2Y5), NRK_MOUSE (Q9R0G8), RGF1_SCHPO (Q9Y7U6), RGF2_SCHPO (Q9UTR5), RGF3_SCHPO (Q9Y7U5), ROM1_YEAST (P53046), ROM2_YEAST (P51862), TGFA1_BOVIN (A7MB11), TGFA1_DANRE (A4IG72), TGFA1_HUMAN (Q8WUH2), TGFA1_MOUSE (Q3UR70), TNIK_HUMAN (Q9UKE5), TNIK_MOUSE (P83510), TUS1_YEAST (Q06412), VAM6_SCHPO (O13955), VPS39_ARATH (Q8L5Y0), VPS39_CAEEL (Q1ZXS5), VPS39_DROME (Q9VEA2), VPS39_HUMAN (Q96JC1), VPS39_MOUSE (Q8R5L3), VPS3_ARATH (F4I312), VPS3_SCHPO (O59796), VPS3_YEAST (P23643), Y1510_DICDI (Q54EH3)» more
|
| PDB [Detailed view] |
3 PDB
7Z6E; 8EEC; 8QX8 |