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Entry: PS50245

General information about the entry

Entry name [info] CAP_GLY_2
Accession [info] PS50245
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED; 10-MAY-2017 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00660
Associated ProRule [info] PRU00045

Name and characterization of the entry

Description [info] CAP-Gly domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=44;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=40;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.3912000; R2=0.0139045; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2675.9406738; R2=1.5437037; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=584; H_SCORE=3577; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=440; H_SCORE=3355; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-20; I=-20; B1=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='G'; M= -3,-10,-30,-10,-17,-28, 54,-17,-38,-11,-28,-18,  0,-20,-15, -4, -2,-18,-28,-20,-27,-17;
/M: SY='P'; M=  3, -9,-24, -6,  9,-22,-18,-16,-13, -6,-16,-13,-12, 20, -5,-13,  0,  0,-10,-28,-20,  1;
/M: SY='V'; M= -3,-16,-16,-18,-10, -8,-27,-22, 13,-14,  1,  1,-16,-18,-15,-16, -2,  9, 21,-29,-10,-13;
/M: SY='E'; M=-10,  8,-28, 15, 22,-30,-15, 11,-27, -1,-25,-16,  3,  5, 13, -5,  4, -6,-27,-32,-14, 16;
/M: SY='F'; M= -9,-11,-23,-16,-15,  8, -8,-16,-10,-18, -3, -7, -4, -7,-19,-16, -7, -1,-11,-19, -6,-17;
/M: SY='K'; M= -1, -9,-25,-10, -3,-24, -3,-12,-20, 13,-19, -8, -5,-16,  3, 12, -5, -9,-11,-21,-15, -1;
/M: SY='P'; M=  6, -1,-27,  1,  3,-29,-13,-14,-23,  8,-24,-16, -6, 19, -3, -5, -3, -7,-19,-26,-20, -2;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='M'; M= -3,-21,-23,-26,-19, -1,-23,-10, 13,-14,  5, 18,-20, -7,-11,-17,-14, -7,  8,-14,  6,-17;
/M: SY='W'; M=-20,-34,-38,-37,-29, 34,-24,-20,-11,-22, -8,-11,-31,-30,-24,-19,-31,-21,-18, 91, 37,-23;
/M: SY='V'; M=  1,-24,  3,-28,-24, -1,-27,-21, 12,-21,  8,  4,-23,-27,-22,-21,-12, -5, 18,-21, -1,-24;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='I'; M= -6,-30,-20,-34,-29,  1,-34,-29, 37,-26, 20, 16,-26,-26,-24,-24,-17, -6, 35,-24, -4,-29;
/M: SY='E'; M=-12, 14,-30, 24, 47,-33,-18,  2,-30,  8,-22,-18,  3, -3, 24,  0,  0,-10,-30,-30,-18, 35;
/M: SY='L'; M=-13,-30,-26,-30,-21, 13,-29,-14, 11,-25, 32, 11,-30,-30,-18,-18,-30,-13,  1, 12, 18,-20;
/M: SY='D'; M=-16, 14,-26, 25,  2,-18,-19, -9,-13,-13,  6, -8, -2,-19, -9,-14,-13,-10,-12,-31,-11, -3;
/I:         I=-5; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='E'; M=  9,  6,-20,  2, 16,-23,-11, -8,-20,  5,-18,-15,  5, -8,  3, -3,  6,  2,-16,-27,-18, 10;
/M: SY='P'; M=-10, -6,-35, -1,  9,-28,-17,-12,-21, -6,-29,-20, -5, 60, -4,-14, -5, -8,-30,-32,-27, -1;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='L'; M=-12,-13,-22,-21,-16,  8,-25,-14,  5,-15, 11,  3, -6,-23,-15, -5,-12, -1,  0,-20, -1,-16;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='K'; M=-10,  0,-30,  0, 10,-30,-20,-10,-30, 50,-30,-10,  0,-10, 10, 30,-10,-10,-20,-20,-10, 10;
/M: SY='H'; M=-15, 22,-25, 11,  0,-20, -9, 51,-25, -5,-25,-11, 37,-20,  5,  0,  1, -9,-30,-35, -2,  0;
/M: SY='D'; M=-20, 41,-30, 58, 17,-37,-11,  0,-39,  4,-29,-27, 17,-11,  1,  2, -1,-10,-29,-37,-19,  9;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='S'; M=  4, -8,-12,-11, -9,-12,-11,-13, -4,-11,-13,  0, -3,-15, -6,-11, 19, 16,  4,-34,-14, -8;
/M: SY='F'; M= -3,-23,-16,-28,-23, 19,-25, -8,  8,-20,  3,  3,-19,-26,-25,-17,-11, -6, 18,-17,  5,-23;
/M: SY='K'; M=-11, 11,-27, 11, 14,-27,-16,  0,-21, 16,-20, -3,  7,-11, 14,  7, -5, -9,-21,-27,-13, 14;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='T'; M= -6,-13,-18,-18,-13,-11,-25,-19,  2,  0, -5, -1,-10,-18,-11,  3, -2, 11, 11,-26, -9,-13;
/M: SY='R'; M= -9, -6,-24, -4,  9,-23,-18, -6,-19, 15,-19, -9, -3,-14, 11, 22,  0, -4,-12,-26,-13,  8;
/M: SY='Y'; M=-20,-22,-28,-23,-22, 39,-30, 13,  0,-13,  2,  0,-20,-30,-15,-12,-20,-10, -8, 27, 71,-22;
/M: SY='F'; M=-20,-30,-20,-40,-30, 80,-30,-20,  0,-30, 10,  0,-20,-30,-40,-20,-20,-10,  0, 10, 30,-30;
/M: SY='Q'; M=-11,  4,-30,  6, 17,-30,-22, -4,-17, 14,-18, -7,  0,-10, 20,  6, -6,-10,-18,-24,-12, 18;
/M: SY='C'; M=  2,-14, 44,-24,-21,-15,-24,-26,-11,-21,-11,-11,-13,-24,-20,-23,  1,  9, -1,-36,-19,-21;
/M: SY='K'; M=-11,  3,-29,  7, 13,-27,-19, -9,-27, 16,-24,-16, -1,  7,  4, 12, -3, -1,-22,-27,-16,  7;
/I:         I=-4; MD=-19;
/M: SY='H'; M= -9, -1,-14, -4, -6,  0,-11, 16, -5, -7, -1,  0,  3,-14, -3, -4, -7, -6, -9, -8, 12, -6; D=-4;
/I:         I=-4; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='P'; M=-10,-13,-36, -6,  6,-28, -9,-14,-26, -1,-27,-18,-11, 44, -3, -2, -7,-11,-28,-27,-25, -2;
/M: SY='Y'; M=-11,-11,-26,-12, -4, -6,-24, -2, -9,  6, -4, -1,-11,-19,  4,  2,-10, -2,-11, -8, 16, -1;
/M: SY='H'; M= -8, -4,-24, -5, -3,-17, -6, 24,-21, -8,-19, -7,  2,-17,  8, -5,  4, -1,-20,-21,  5,  0;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='I'; M= -6,-21,-23,-25,-20, -5,-10,-19, 13,-23, 13, 12,-15,-21,-15,-20,-11, -8,  6,-23, -8,-19;
/M: SY='F'; M=-18,-28,-20,-38,-28, 66,-28,-17,  3,-27, 12, 10,-20,-28,-33,-18,-20,-10,  2,  5, 25,-27;
/M: SY='V'; M=  3,-26,  0,-31,-27, -5,-29,-29, 23,-23,  6,  6,-23,-25,-24,-24,-10, -4, 30,-28,-11,-27;
/M: SY='R'; M=-14,-10,-33, -7,  4,-27,-20, -6,-26, 18,-24,-11, -6, 15, 12, 30, -8,-10,-24,-23,-16,  4;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 76 in 54 different sequences
Number of true positive hits 76 in 54 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann, CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Feature key [info] DOMAIN
Feature description [info] CAP-Gly
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
54 sequences

ALP11_SCHPO (Q10235    ), BIK1_YEAST  (P11709    ), CE350_HUMAN (Q5VT06    ), 
CE350_MOUSE (E9Q309    ), CL190_DROME (Q9VJE5    ), CLIP1_CHICK (O42184    ), 
CLIP1_HUMAN (P30622    ), CLIP1_MOUSE (Q922J3    ), CLIP1_RAT   (Q9JK25    ), 
CLIP2_HUMAN (Q9UDT6    ), CLIP2_MOUSE (Q9Z0H8    ), CLIP2_RAT   (O55156    ), 
CLIP3_HUMAN (Q96DZ5    ), CLIP3_MOUSE (B9EHT4    ), CLIP3_PONAB (Q5R686    ), 
CLIP3_XENLA (Q5U243    ), CLIP4_HUMAN (Q8N3C7    ), CLIP4_MOUSE (Q8CI96    ), 
CLIP4_RAT   (Q66HD5    ), CLP1H_CAEEL (P34531    ), CYLD_BOVIN  (Q1RMU2    ), 
CYLD_HUMAN  (Q9NQC7    ), CYLD_MOUSE  (Q80TQ2    ), CYLD_PONAB  (Q5RED8    ), 
CYLD_RAT    (Q66H62    ), DCTN1_CHICK (P35458    ), DCTN1_DROME (P13496    ), 
DCTN1_HUMAN (Q14203    ), DCTN1_MOUSE (O08788    ), DCTN1_RAT   (P28023    ), 
DCTN1_XENLA (Q6PCJ1    ), DYNA_NEUCR  (Q01397    ), KI13B_HUMAN (Q9NQT8    ), 
NIP80_YEAST (P33420    ), PAC2_YEAST  (P39937    ), SSM4_SCHPO  (O42667    ), 
TBCB_ARATH  (Q67Z52    ), TBCB_BOVIN  (Q5E951    ), TBCB_CAEEL  (Q20728    ), 
TBCB_DICDI  (Q54Z01    ), TBCB_HUMAN  (Q99426    ), TBCB_MOUSE  (Q9D1E6    ), 
TBCB_YEAST  (P53904    ), TBCE_ARATH  (Q8GRL7    ), TBCE_BOVIN  (Q32KS0    ), 
TBCE_DANRE  (Q5U378    ), TBCE_DICDI  (Q55CN0    ), TBCE_DROME  (A1Z6J5    ), 
TBCE_HUMAN  (Q15813    ), TBCE_MOUSE  (Q8CIV8    ), TBCE_PONAB  (Q5RBD9    ), 
TBCE_RAT    (Q5FVQ9    ), TBCE_XENLA  (Q5U508    ), TIP1_SCHPO  (P79065    )
» more

PDB
[Detailed view]
33 PDB

1IXD; 1LPL; 1TOV; 1TXQ; 1WHG; 1WHH; 1WHJ; 1WHK; 1WHL; 2COW; 2COY; 2COZ; 2CP0; 2CP2; 2CP3; 2CP5; 2CP6; 2CP7; 2E3H; 2E3I; 2E4H; 2HKN; 2HKQ; 2HL3; 2HL5; 2HQH; 2M02; 2MPX; 2QK0; 2Z0W; 3E2U; 3RDV; 3TQ7
» more

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